47results about How to "Reduce function" patented technology

The invention discloses a communication method for an enterprise network and remote router equipment of a DCS (Distributed Control System). A communication adaptation module is arranged at an enterprise network end and comprises a protocol conversion unit, a data encryption unit, a flow regulation and control unit and a timestamp embedding unit; the far-end router equipment end is provided with a corresponding reverse communication adaptation module. Two-way interaction of data and control instructions is realized through a two-way communication link, and a dynamic link detection and repair sub-module is configured to guarantee stability of the link. According to the method, the problems of protocol compatibility, data security, flow regulation and control, time management, link maintenance and the like are solved, the communication efficiency and quality are improved, efficient, safe and stable operation of remote communication and control functions of the DCS in industrial production is ensured, and the method has a good application prospect.

The invention discloses a detection method for influence of PGRN regulation on cerebellar synaptic development of ASD rats, and relates to the technical field of autism spectrum disorders. The method specifically comprises the following steps: step 1, breeding an experimental rat; 60 Sprague-Dawley rats in the childbearing age are purchased, the female-male ratio is 2: 1, the rats freely eat and drink water, and the rats are fed for three to five weeks; step 2, preparing a VPA induced ASD rat model; experimental rats are subjected to fertilization culture, female rats are randomly divided into two groups after being fertilized for 12.5 days, a VPA solution is injected into the VPA group through the abdominal cavity, and sterile normal saline with the same volume is injected into the control group. The detection method shows that the PGRN can obviously relieve VPA-induced dyskinesia and autism-like behaviors of ASD rats and relieve cerebellar Purkinje cell synaptic dysplasia, and the mechanism of the PGRN is possibly related to inhibition of the PGRN on lysosomal functions and autophagy activities in cerebells of the ASD rats.

The present invention relates to a method based on D 2 Terahertz phased array device of NNs and implementation method thereof. The phased array device includes an active modulation layer and a two-layer metasurface layer structure. The active modulation layer mainly includes patterned micro-nano metal electrodes and active functional materials, and the optical properties of the active functional materials are adjusted by applying an external voltage, so as to achieve a beam output with a specific phase distribution in the terahertz band. The metasurface layer is composed of a silicon pillar structure array located on the surface of the substrate. The two metasurface layers can finely control the complex electric field distribution of a specific diffraction plane to construct an optical diffraction neural network architecture. For each required control mode, the phase distribution of the metasurface layer is optimized using the gradient descent and back propagation algorithms in the neural network, and active control of a specific beam direction can be achieved under different voltage drives. The present invention solves the problems of terahertz phased array technology in terms of control accuracy, continuity, etc., and provides a more efficient and flexible beam control method.

The invention belongs to the technical field of medicines, and provides application of fritillaria alkaloid in preparation of a medicine for treating cardiomyopathy induced by chemotherapeutic drugs. The fritillaria alkaloid is fritillaria pallidiflora alkaloid; the chemotherapeutic drug is an anthracycline chemotherapeutic drug; the anthracycline chemotherapeutic drug is adriamycin. The fritillaria pallidiflora alkaloid can prevent and / or treat doxorubicin-induced cardiomyopathy by resisting myocardial fibrosis and relieving myocardial damage. The fritillaria pallidiflora alkaloid is a natural fritillaria pallidiflora alkaloid, through a multi-target action mechanism, cardiac function decline and cardiomyopathy damage caused by adriamycin are effectively relieved, and a novel candidate drug with potential and a treatment strategy are provided for preventing or treating chemotherapy drug induced cardiomyopathy.

The application provides a multi-chip stacked package structure and a preparation method thereof. The multi-chip stacked package structure comprises a first chip distributed on a substrate, a side surface of the first chip being covered by a first plastic package structure; a second chip stacked on the first chip, a side surface and a bottom surface of the second chip being covered by a second plastic package structure; and a heat dissipation structure comprising micro-flow channels located on both sides of the first chip and the second chip, the micro-flow channels penetrating a top surface of the second plastic package structure and extending to a bottom surface of the first plastic package structure, and side surfaces of the micro-flow channels being covered by the first plastic package structure and the second plastic package structure. The multi-chip stacked package structure can quickly conduct the heat generated by the chips to the outside of the overall package structure, avoid the accumulation of heat in the plastic package structure, and ensure the reliability and service life of the device.

The application relates to the technical field of integrated circuits and provides a high-speed serial interface physical IP verification platform, method, device and medium. The application provides a unified design and verification platform supporting coexistence and fusion of multiple protocol types and a multi-protocol physical layer intellectual property core design and verification, is based on a modular, parameterized, multi-protocol and harmonious coexistence design idea and a top-level architecture circuit design method, can effectively reduce the circuit design and verification manpower cost of various different protocol types in project development, significantly shortens the function and performance verification period of the physical layer intellectual property core, significantly improves the full-stack and full-field research and development efficiency of the architecture design, circuit development and full-amount function / performance verification for different protocol types, improves the design and verification platform reuse degree between different protocols, and provides an excellent paradigm of unified design and verification with high platform level.

The application provides a composition for improving memory and reducing blood lipid, a preparation method and application thereof, and belongs to the technical field of food, health care products and medicines. In order to solve the problems in the prior art, such as too simple components of health care products with the functions of reducing blood lipid or improving memory, difficulty in achieving the effect, too complex formula, large dosage, lack of function and safety evaluation, and difficulty in evaluating the effect, the application provides a composition which is mainly composed of walnut oil, soybean phospholipid, ginkgo leaf extract and natural vitamin E as raw materials, and suitable excipients, wherein the excipients are soybean oil, beeswax, gelatin, glycerol, purified water, titanium dioxide and cocoa shell pigment. The scientific and reasonable production process is adopted to process the suitable product, so that the function and effect of reducing blood lipid and improving memory are achieved.

This utility model discloses a detection device belonging to the field of X-ray detection technology, specifically an offline X-ray multi-angle detection device, comprising: a lead room, an imaging system, and a detection platform; the imaging system and the detection platform are installed in the lead room, and the imaging system is installed on the detection platform; the lead room is welded from a steel-lead steel structure to provide X-ray protection; the imaging system includes a radiation source fixing module and an imager motion module; the detection platform has structural motion in three directions: X-axis, Y-axis, and Z-axis, including an X-axis drive module, a Y-axis drive module, and a Z-axis drive module; this utility model provides a relatively economical, efficient, and widely applicable online X-ray multi-angle material detection device. It not only meets customers' needs for convenient and efficient 2.5D detection but also greatly reduces customers' procurement costs and eliminates the problem of functional redundancy, meeting the general needs of low-end customers in the industry.

The invention discloses a large-torque ultrathin permanent magnet brake and belongs to the technical field of permanent magnet brake production, the large-torque ultrathin permanent magnet brake comprises an outer groove disc, an inner groove disc, an electromagnetic coil, a retainer and a permanent magnet, the outer groove disc comprises an outer cylinder and an outer disc, the inner wall of the outer disc and the outer wall of one end of the outer cylinder are connected and integrally formed, and the inner groove disc comprises an inner cylinder and an inner disc; the inner wall of the inner disc and the outer wall of one end of the inner cylinder are connected and integrally formed, the part, close to the center position, of the surface of one side of the inner disc is the cavity wall surface of one side of the coil inner cavity, and the permanent magnet and the annular retainer are located between the part, close to the edge position, of the surface of one side of the inner disc and the outer disc. The purposes of remarkably increasing the braking torque and reducing the coil function and temperature rise on the premise that the axial size of the brake is not increased are achieved, finally the purposes of large torque, small power, small temperature rise and ultra-thin (namely extremely-small axial size) functions are achieved, and the application requirements of humanoid robots and other products with extremely-small axial size requirements are met.

The utility model discloses a grounding resistance online monitor, which relates to the field of monitoring equipment and comprises a central processing module, an LCD (liquid crystal display) display module, a communication module, a grounding acquisition module, a power management module and an analog-to-digital conversion module, the output end of the grounding acquisition module is connected to the input end of the analog-to-digital conversion module, and the output end of the analog-to-digital conversion module is respectively connected to the central processing module and the grounding acquisition module; the grounding acquisition module is provided with a first acquisition end P and a second acquisition end C. The power management module is connected with the grounding acquisition module to supply power to the whole device. According to the utility model, the numerical value of the grounding resistance can be regularly recorded and automatically calibrated, multiple lightning induction voltage avoiding or recovering capabilities are provided, and the lightning induction and self-calibration functions are effectively slowed down, so that the manual operation requirement is reduced, and the equipment maintenance cost is reduced.

The present invention relates to anti-FcRH5 antibodies, including anti-FcRH5 antibodies comprising an FcRH5 binding domain and a CD3 binding domain (e.g., FcRH5 T cell-dependent bispecific (TDB) antibodies), and methods of using the same.

The utility model provides a glass curtain wall cleaning structure and a glass curtain wall, which belong to the technical field of glass curtain walls and comprise hollow toughened glass, an inner cavity cleaning mechanism and a reversing locking mechanism. Wherein the two pieces of hollow tempered glass are arranged in parallel at intervals, the edges of the two pieces of hollow tempered glass are used for being fixedly connected into a wall body of a glass curtain wall, and a middle cavity is defined between the two pieces of hollow tempered glass. The inner cavity cleaning mechanism is movably arranged in the middle cavity in the longitudinal direction, and brush heads making contact with the inner walls of the two pieces of hollow tempered glass are arranged on the two sides of the inner cavity cleaning mechanism. The reversing locking mechanism is arranged on the inner cavity cleaning mechanism and is configured to drive the brush head to automatically reverse when the inner cavity cleaning mechanism reaches the top or the bottom of the middle cavity. A series of adverse effects of reduction of local sealing performance of an existing glass curtain wall structure on the curtain wall appearance, the lighting function and the energy-saving effect can be reduced.

The utility model relates to a thermal -insulated quilt roll -out equipment technical field, concretely is a kind of thermal -insulated quilt limiting device, including base rod and the connecting rod connected with the base rod, two support tubes are fixedly arranged on base rod, rotatably connected with movable arm between two support tubes, the connecting rod on the side away from the support tube is fixed with adjusting assembly, and the adjusting assembly upper end is equipped with switch assembly. The utility model adopts the non-contact switch assembly of hall sensor and magnetic piece, replaces traditional mechanical contact structure, avoids the abrasion problem caused by mechanical friction, prolongs service life;Non-contact detection is not interfered with by greenhouse outside water vapor, dust simultaneously, greatly reduces malfunction or malfunction probability, ensures that roll-up curtain system stable trigger stop, reduces equipment damage, thermal -insulated quilt drop risk.

This application relates to an electromagnetic induction coil frame, including an inner frame, insulating columns, an insulating support plate, and an insulating plate. The inner frame is a cuboid, connected by multiple columnar structures bolted together. Multiple insulating columns are evenly distributed on the sides of the inner frame, with the insulating columns on both sides corresponding to each other. The insulating support plate includes upper and lower support plates, which are bolted to the front of the inner frame. The combined shape matches the front of the inner frame, with semi-circular openings of equal radius on the long side. The shape of the insulating plate matches the lower support plate. Multiple insulating plates are fixed between corresponding insulating columns in groups of at least two. This electromagnetic induction coil frame avoids closed-loop heating through a channel steel connection design. The insulating columns provide support to prevent heating from magnetic lines of force, resulting in a stable structure. The detachable design facilitates transportation, installation, inspection, and maintenance. The materials are lightweight and cost-effective. The outer protective cover of the insulating plate provides dust and electric shock protection. Overall insulation reduces potential hazards and meets equipment support requirements.

The invention discloses a flow cell magnetic labeling microdevice based on ultrasound, comprising a microfluidic chip and an ultrasonic device, wherein a first channel, a second channel, a mixing channel and a labeling channel are arranged inside the microfluidic chip, the first channel is used to inject a cell suspension, the second channel is used to inject a magnetic nanoparticle solution, the first channel and the second channel are respectively provided with injection ports on the surface of the microfluidic chip, the first channel and the second channel are both connected to the inflow end of the mixing channel, the outflow end of the mixing channel is connected to the inflow end of the labeling channel, the outflow end of the labeling channel is provided with a mixed liquid outlet on the surface of the microfluidic chip, and the flow area of ​​the mixing channel is smaller than the flow area of ​​the labeling channel; the ultrasonic device comprises a container and an ultrasonic transducer arranged at the bottom of the container, and the ultrasonic transducer is connected to a matching circuit. This scheme can continuously, quickly and safely carry out sufficient magnetic labeling of cells in batches, reducing the influence on the activity and proliferation function of the cells.

The present invention aims to provide a composition for reducing renal function decline or ameliorating renal function and a method of reducing renal function decline or ameliorating renal function. The present invention relates to a composition for reducing renal function decline or ameliorating renal function, the composition containing L-ergothioneine or a salt thereof as an active ingredient.

The invention relates to a file management method, device and system and a storage medium. The method comprises the steps that when an operation request of a client for a target file is received, metadata management operation matched with the operation request is executed in an embedded database of a file management system through a metadata manager of the file management system, and metadata of the target file is obtained; the metadata comprises a data reference identifier; analyzing the data reference identifier to obtain a data storage position; the data storage position is used for indicating a storage position of the target file in a target data storage rear end, and the target data storage rear end is one of a plurality of data storage rear ends butted with a storage abstraction layer of the file management system; and executing a file management operation matched with the operation request on the target file based on the data storage position in the target data storage rear end through a storage abstraction layer of the file management system. According to the scheme provided by the invention, the problems of function redundancy and hierarchical redundancy in the related technology can be solved.

The utility model discloses a schoolbag with talk function, it includes schoolbag, is equipped with at least one shoulder strap on the schoolbag, and one of the shoulder strap is detachably installed with communication equipment, and the communication equipment includes shell, locking piece and strong magnet unlocker, is equipped with lock cylinder and circuit board in the shell interior, is equipped with at least battery, central processing chip to the circuit board, and and central processing chip respectively connected's wireless communication module, positioning module and touch module, and locking piece includes spacing block and steel needle, is equipped with the insertion hole of steel needle in the shell to the lock cylinder is inserted, to install communication equipment on the shoulder strap, the utility model is very mini light and clever, installs it on the shoulder strap of schoolbag, has no weight burden, will not influence the normal back wearing of schoolbag shoulder strap, possesses two -way talk, sos alarm, real -time positioning function, and parents can locate the position of children through mobile phone app in real time, is more reassured, and simple function, will not influence the study of children, and the practicality is strong.

This invention discloses a unified intermediate representation data model and construction method for hardware design, belonging to the field of electronic design automation. The model includes: a unified representation base class; structural relationship graph representation and temporal behavior representation, describing the structural composition and runtime behavior of the design, respectively; formal semantic consistency constraints to ensure semantic consistency between structure and behavior; and a semantic association architecture to establish bidirectional semantic mapping between various scenario representations such as HDL code, schematics, and waveforms and the unified representation base class. The construction method based on this model includes an incremental synchronization process, achieving automatic synchronization after any representation modification through change capture, cross-representation mapping indexing, and change propagation rules. This invention also provides an AI-assisted design method based on this model, improving AI interaction efficiency and the automation level of design verification through multi-dimensional context construction, syntax stripping, incremental interaction protocols, and automatic closed-loop verification.

The invention relates to a low-power-consumption power-on reset circuit, which realizes low-power-consumption and high-stability power-on reset and power-on detection functions by utilizing the hysteresis characteristic of a Schmitt trigger and combining the complementary control of a PMOS (P-channel Metal Oxide Semiconductor) transistor and an NMOS (N-channel Metal Oxide Semiconductor) transistor. Not only is necessary reset time delay provided, but also power consumption of the circuit in the starting process is reduced. Meanwhile, in order to further improve the performance, a voltage detection hysteresis function is provided, an additional protection mechanism is provided, and the situation that the voltage is too low due to power supply fluctuation is prevented. Compared with the prior art, the power-on reset circuit has the advantages that the overall power consumption of the power-on reset circuit is remarkably reduced by utilizing the low power consumption characteristic of the CMOS transistor, the reset stability of the circuit is ensured through accurate voltage detection and delay control, the response speed of the circuit to the power supply change is improved through the optimized voltage detection module, the circuit design is simple, and the cost is low. And the method is easily compatible with the existing integrated circuit process.

The invention belongs to the technical field of biology, and particularly relates to application of nuciferine in preparation of a medicine for relieving pyroptosis of trophoblasts in preeclampsia. Nuciferine inhibits activation of NLRP3 inflammasomes and reduces caspase-1 cleavage and GSDMD mediated pyroptosis, so that placenta inflammation and dysfunction are relieved, and preeclampsia symptoms are improved. The nuciferine remarkably improves the symptoms of fetal growth limitation and placenta weight reduction of preeclampsia mice, and reduces placenta oxidative stress and inflammation level. In a cell model, nuciferine effectively reverses the pyroptosis phenotype of trophoblast cells, and the protein expression of NLRP3, cleaved-caspase-1, GSDMD-NT and IL-1beta is remarkably reduced. The application potential of nuciferine as a promising natural medicine in preeclampsia treatment is clarified, and the understanding of the relationship between inflammation and pyroptosis in preeclampsia pathogenesis is deepened.

According to the automatic batching and mixing device for radioactive waste solidification treatment, a screen is installed on the front face of a working main cabinet, and the position numbers and the grabbing times of all materials can be input in advance. The working main cabinet is connected with the upper cover through a first hinge and a second hinge, a switch is installed on the right side of the working main cabinet, a conveying structure is fixed to the lower portion in the working main cabinet and can enable the feeding structure and the material disc structure to move left and right, and a first support and a second support are fixed to the upper portion and the right side in the working main cabinet respectively. The telescopic structure is connected with the first support and the second support in a fastened mode, the lower end of the telescopic structure is connected with the grabbing structure in a fastened mode, so that the grabbing structure moves up and down, and materials such as radioactive nuclear waste, solidified base materials and additives are grabbed through the grabbing structure. According to the device, on the premise that workers do not make contact with the radioactive waste, materials such as the radioactive nuclear waste are quantitatively grabbed and mixed and solidified, so that the nuclear radiation function is reduced, and the harm of radiation to the workers is reduced.

The present application discloses a method for constructing a model library of a driverless car VCU control system based on Modelica, the method comprising: determining the vehicle parameters of the driverless car and the corresponding vehicle control schematic diagram of the VCU control system, and dividing the functional requirements of the VCU control system to determine the functional modules; determining the correspondence between the input signal and the actual output control signal under different driving states, and establishing a logic judgment module based on the correspondence and the preset electrical signal interface module; establishing a signal interface based on the functional requirements of the VCU control system, connecting the signal interface with the logic judgment module, and establishing a functional module model of the functional module; according to the vehicle control schematic diagram, connecting the functional module models in sequence and performing closed-loop simulation tests to adjust the functional module models. Through the technical solution in the present application, the problems of incomplete configuration of basic vehicle parameters and missing vehicle interface functions in the VCU control system modeling in the related technology are solved.

The application belongs to the technical field of biological medicine, and relates to a BCLAF1 protein Ser564 site phosphorylation antigen peptide, a specific antibody and a preparation method and application thereof. The application identifies BCLAF1 protein Ser564 as a key phosphorylation site through SIK2 kinase screening, and designs and synthesizes a phosphorylation antigen peptide based on the site. After immunizing animals, a polyclonal antibody specifically recognizing BCLAF1 Ser564 site phosphorylation modification is successfully prepared. The antibody has high sensitivity and strong specificity, is suitable for various detection platforms such as immunohistochemistry and immunoblotting, and can be used for evaluating tumor immunotherapy efficacy. The application provides a key tool for analyzing BCLAF1 phosphorylation regulation mechanism, and lays a theoretical foundation for developing an immune combined therapy strategy targeting a SIK2-BCLAF1-CCL5 axis.

The present invention provides a low-profile room-separated antenna, which relates to the field of antenna technology. The low-profile room-separated antenna includes: a first dielectric substrate, a second dielectric substrate, a third dielectric substrate and a fourth dielectric substrate connected in sequence, each of which has a compact structure to achieve a low-profile effect. Moreover, since a plurality of first short-circuit posts, a plurality of second short-circuit posts and a plurality of third short-circuit posts are distributed in a semicircular shape, the circularity of the directional pattern of the radiation signal can be improved. Due to the presence of the second resonant cavity, the function of frequency selection filtering is realized, so that the low-profile room-separated antenna integrates the heterodyne decoupling capability. Compared with the existing quasi-omnidirectional antenna, the low-profile room-separated antenna has the advantages of high performance, low profile and simple structure in addition to realizing the out-of-band harmonic suppression function, and realizes the integrated integration of antenna and filter and functional fusion.

The utility model relates to an anti-disassembly key and an electric appliance, and belongs to the field of electric appliances. An anti-dismounting button comprises a housing assembly which is provided with an installation space, a movable groove and an installation hole; the limiting assembly is arranged on the shell assembly and located in the installation space, and the limiting assembly is spliced with the shell assembly; the pushing assembly is arranged on the shell assembly and located at the movable groove; and the driven assembly is arranged on the shell assembly and located in the mounting space, the pushing assembly and the driven assembly are arranged on the two sides of the mounting hole respectively and spliced, and the pushing assembly can drive the driven assembly to abut against the limiting assembly. According to the anti-disassembly key, the limiting assembly and the shell assembly are spliced through the ultrasonic welding technology, the pushing assembly and the driven assembly are spliced through the ultrasonic welding technology, and easy disassembly caused by loose connection is effectively prevented.

The invention belongs to the field of medicines, and discloses application of an LMP1 expression inhibitor in regulation and control of MCM3 protein. The inventor finds that the LMP1 protein is related to drug resistance of NKTCL cells to drugs synthesized by targeted DNA through research. The LMP1 interacts with a key protein MCM3 synthesized by DNA of a host, other signal channels, related to cell cycle regulation and DNA repair, of the host are influenced through the LMP1-MCM3 type, and overexpression of the LMP1 promotes survival of tumor cells and inhibits cell apoptosis, so that the effect of a chemotherapeutic drug is reduced; knockdown of the LMP1 can significantly enhance the sensitivity of cells to drugs. The function of MCM3 can be reduced by inhibiting the expression or function of LMP1. The interaction between EBV and host cells can be broken, and the curative effect of chemotherapeutic drugs such as cytarabine which are widely used clinically is improved. In addition, the strategy can also be used for preventing reactivation of EBV and reducing the occurrence risk of virus-related tumors.