798results about "Blood transfusion" patented technology

In some embodiments, a system can include a fluid delivery assembly and a motor drive assembly. The fluid delivery assembly is configured to be releasably mechanically and, optionally, electrically coupled to the motor drive assembly. When the fluid delivery assembly is releasably coupled to the motor drive assembly, the motor drive assembly can control delivery of fluid from the fluid delivery assembly (e.g., to a patient). For example, the motor drive assembly can be releasably coupled to the fluid delivery assembly to control delivery of fluid from the fluid delivery assembly to provide continuous (e.g., non-pulsatile) fluid flow from the fluid delivery assembly.

Described are embodiments that include methods and devices for separating components from multi-component fluids. Embodiments may involve use of separation vessels and movement of components into and out of separation vessels through ports. Embodiments may involve the separation of plasma from whole blood. Also described are embodiments that include methods and devices for positioning portions, e.g., loops, of disposables in medical devices. Embodiments may involve use of surfaces for automatically guiding loops to position them into a predetermined position.

The present invention includes a spray drying disposable device for use in a spray drying system. The disposable has a spray drying head and a plasma drying chamber. The head has a spray dry nozzle assembly in fluid communication with the plasma source and the pressurized aerosol gas source. The pressurized gas flows in a vortex pattern that atomizes plasma droplets in the chamber. The head also includes a plenum has uniform air pressure of the drying gas. A baffle plate forms the floor of the plenum having drying gas jets that supply drying gas to the chamber. The atomized plasma droplets evaporate in the presence of the drying gas emitted from the jets to obtain dried plasma particles and humid air. A capture filter captures the dried plasma particles and allows the humid air to pass. The humid air passes through the gas outlet and the exhaust port.

An object of the present invention is to provide a method for preserving a platelet in a refrigerated or frozen state while retaining more platelet functions, a platelet preservation solution for use in such a method, and the like. The present invention relates to a platelet preservation solution for refrigeration or freezing, comprising an electrolyte and an anticoagulant. The present invention also relates to a method for preserving a platelet, comprising: suspending a platelet in the platelet preservation solution according to the present invention; and preserving the suspension by refrigeration or freezing at 10°C or lower.

The present invention includes a spray drying disposable device for use in a spray drying system. The disposable has a spray drying head and a plasma drying chamber. The head has a spray dry nozzle assembly in fluid communication with the plasma source and the pressurized aerosol gas source. The pressurized gas flows in a vortex pattern that atomizes plasma droplets in the chamber. The head also includes a plenum has uniform air pressure of the drying gas. A baffle plate forms the floor of the plenum having drying gas jets that supply drying gas to the chamber. The atomized plasma droplets evaporate in the presence of the drying gas emitted from the jets to obtain dried plasma particles and humid air. A capture filter captures the dried plasma particles and allows the humid air to pass. The humid air passes through the gas outlet and the exhaust port.

A prismatic reflector is provided for incorporation into a centrifugal separation chamber. The prismatic reflector is formed of a light-transmissive material and includes inner and outer walls and first and second end walls. The inner wall is configured to receive light traveling along an initial path and transmit the light to the first end wall, with the first end wall receiving the light transmitted through the inner wall and directing the light toward the second end wall in a direction that is angled with respect to the initial path. The second end wall receives the light from the first end wall and transmits the light out of the prismatic reflector. The initial path of the light may be in a direction toward a rotational axis of the centrifugal separation chamber, with the prismatic reflector redirecting the light into a direction substantially parallel to the rotational axis.

The invention relates to the technical field of medical instruments, and discloses an isolation melting device and a pulp melting machine. The isolation melting device comprises a fixed frame which defines a mounting space; the movable support comprises a first support and a second support, one end of the first support is rotatably connected with one end of the second support, and the other end of the first support and the other end of the second support can move towards each other or away from each other; the bag body is provided with a bag opening and is connected with the first bracket and the second bracket; wherein the movable support can move into or out of the installation space, when the movable support moves into the installation space, the installation space limits the first support and the second support, the first support and the second support move oppositely, the bag body shrinks, and the area of the bag opening is reduced; when the movable support moves out of the installation space, the installation space relieves limiting of the first support and the second support, the first support and the second support move away from each other, the bag body expands, and the area of the bag opening is increased. Placement convenience of the plasma bag is improved, and heat exchange efficiency is improved.

A fluid processing system includes a fluid processing device and a fluid flow circuit. The device includes a pump configured to convey a priming fluid through the circuit. The pressure in a conduit of the circuit is measured while the pump is operated at a particular rate. When the magnitude of the pressure is less than the magnitude of a predetermined pressure at the end of a time interval, the pump is operated at an increased rate. When the magnitude of the pressure is greater than the magnitude of the predetermined pressure at the end of the time interval, the pump is instead operated at a decreased rate. The magnitude of the pressure in the conduit is again compared to the magnitude of the predetermined pressure after the pump has operated at the increased or decreased rate for the time interval to determine how to next adjust the operational rate.

The utility model discloses a platelet shaking device for blood transfusion, which relates to the technical field of shaking devices and comprises a shaking box and a box cover. The device comprises a shaking box, a box cover is arranged on the upper side of the shaking box, a placement assembly is arranged in the middle of the interior of the shaking box and comprises an objective table, an electronic scale and a heat preservation plate, the objective table is arranged in the middle of the interior of the shaking box, a cavity is formed in the objective table, the electronic scale is fixedly arranged at the bottommost part of the cavity, and the heat preservation plate is fixedly arranged on the upper side of the electronic scale. A shaking mechanism is arranged on the surface of the rear side of the objective table, and a driving mechanism is arranged on the rear side of the shaking mechanism, so that the blood transfusion bag can be shaken, the cell viability of platelets in blood is further improved, the platelets in the blood are prevented from being accumulated together, and then the body of a patient is prevented from absorbing the platelets in the conveyed blood; the stability of the device can be guaranteed, blood transfusion efficiency can be improved, and practicability is high.

Described are embodiments that include methods and devices for separating components from multi-component fluids. Embodiments may involve use of separation vessels and movement of components into and out of separation vessels through ports. Embodiments may involve the separation of plasma from whole blood. Also described are embodiments that include methods and devices for positioning portions, e.g., loops, of disposables in medical devices. Embodiments may involve use of surfaces for automatically guiding loops to position them into a predetermined position.

The invention discloses a blood bag continuous extrusion method and device, a medium and equipment. The method comprises the steps that the blood bag continuous extrusion process is divided into a plurality of extrusion stages; obtaining a target extrusion parameter, and generating a target pressure value corresponding to each extrusion stage; and the current extrusion pressure is collected, the current extrusion pressure is adjusted to the corresponding target pressure value based on the preset control scheme of each extrusion stage, and continuous extrusion is conducted till the preset extrusion ending condition is met. The extrusion process is divided into a plurality of stages, the actual extrusion pressure of a target monitoring point on a mother bag serves as system input, the running speed of a stepping motor is adjusted in real time through a PID algorithm, and therefore the whole extrusion process is controlled to be within a proper pressure range; and after the pressure reaches the target value, the whole extrusion process is subjected to pressure maintaining according to the set small target pressure, so that the preparation efficiency is high, the hemolysis phenomenon is avoided, the quality of the separation process and the product percent of pass are improved, and the risk of abnormal quality is reduced.

Described are embodiments that include methods and devices for separating components from multi-component fluids. Embodiments may involve use of separation vessels and movement of components into and out of separation vessels through ports. Embodiments may involve the separation of plasma from whole blood. Also described are embodiments that include methods and devices for positioning portions, e.g., loops, of disposables in medical devices. Embodiments may involve use of surfaces for automatically guiding loops to position them into a predetermined position.

A portable centrifuge comprising a base, which includes a rotational mechanism contained within. A sequester wheel having a plurality of concentric rings, forming at least one channel and a central container. The at least one channel comprising a second volume and the central container comprising a first volume. A first cover is disposed over the sequester wheel to create a seal. A second cover is disposed over the first cover and is rotatable to engage with the rotational mechanism to initiate rotation at a predetermined RPM. The whole blood and / or other tissue is separated into its constituent components and deposited into the at least one channel and the central container. Specific volumes of the constituent components may be calculated to match or substantially match the first and second volumes for predetermined volume control and ease of access.

The invention relates to a PRP preparation device and a PRP preparation method, the preparation device comprises a pipe body, an upper cover, a lower cover and a sealing plug, the pipe body comprises an upper section pipe, a middle pipe and a lower section pipe, the upper cover and the upper section pipe are matched to form an upper cavity, the upper cover can move up and down to enable the upper cover to be switched between a first position and a second position, and the upper cover is provided with a liquid injection and suction hole, a liquid suction pipe and a sealing piece; the lower cover is matched with the lower section pipe to form a lower cavity, and the lower cover can move up and down to adjust the volume of the lower cavity; the sealing plug is used for controlling opening and closing of the liquid injection and suction hole and the liquid suction pipe; the part, located in the upper cavity, of the pipette has a set length, and the set length enables the pipette to be located in the platelet-poor plasma layer and keep a gap with the platelet-rich plasma layer when the pipette is located at the second position, and enables the port of the pipette to be located outside the platelet-rich plasma when the port of the pipette is located at the first position. By applying the device, the PRP concentration can be directly adjusted in the preparation device, and the damage to platelets can be avoided when the PRP is extracted.

The present invention refers to a system and method for connecting a concentrate container with a blood treatment device with improved hygiene. Furthermore, the invention refers to a container and blood treatment device to be used in a method according to the present invention.

The present invention refers to a system and method for connecting a concentrate container with a blood treatment device with improved hygiene. Furthermore, the invention refers to a container and blood treatment device to be used in a method according to the present invention.

The utility model discloses a blood platelet rich plasma preparation device which comprises a middle sleeve, an upper storage body, an upper storage cover, a lower storage body and a lower storage cover, a hyperbolic PRP channel and a hyperbolic red blood cell channel are arranged in the upper storage body and the lower storage body respectively, an upper locking bolt and a lower locking bolt are fixed in the middle sleeve, and after the upper locking bolt and the PRP channel are locked in a matched mode, the upper locking bolt and the lower locking bolt are locked in a matched mode. The upper storage body and the upper storage cover form a PRP storage chamber, after the lower locking bolt and the red blood cell channel are matched and locked, the lower storage body and the lower storage cover form a red blood cell storage chamber, the middle sleeve is a plasma storage chamber, a PRP suction opening is formed in the upper storage cover, and the required PRP amount is accurately extracted through the suction opening through the needle head. According to the blood separation device, two times of centrifugal separation can be carried out under the condition that blood is not exposed to air, the blood separation concentration is high, and the PRP extraction amount is accurate.

The present invention relates to a unique method for obtaining secretomes from platelets and the secretome uses in regenerative medicine, in the treatment of diseases, including cell therapy, and in vitro cell culture. This method is developed with the aim of obtaining platelet-derived bio-products enriched in platelet granular cargo, rich in growth factors, and depleted of other platelet-derived molecules and plasma for universal use. The method avoids the use of platelet inhibitors or temperature-shock during the process, assuring the integrity of the platelet biological source. Furthermore, the potential processing of the product would allow additional clinical applications and solve storage limitations. This method and the characterization thereof of secretomes at the molecular level in health and disease will contribute to the identification of biomarkers for disease diagnosis and prognosis.

A blood separation device includes a pump system, a separator, and a controller. The controller is programmed to execute a blood separation procedure including a red blood cell collection stage in which blood is conveyed into the separator, red blood cells are separated from the blood in the separator, and the separated red blood cells are conveyed from the separator into a collection container. The red blood cell collection stage is ended when a target volume of blood has been separated in the separator. The controller then determines a percentage of the red blood cells from the target volume of blood that have been collected in the collection container based on the volume of red blood cells and the hematocrit of the fluid in the collection container, a volumetric flow rate of pure red blood cells in the blood conveyed into the separator, and the procedure time.

The invention relates to the technical field of medical instruments, in particular to a rapid blood recovery and infusion system which comprises a blood storage system and a processing system, the blood storage system comprises a blood storage bag, a blood inlet pipeline and a blood transfusion pipeline, and the blood inlet pipeline and the blood transfusion pipeline are both communicated with the blood storage bag; the treatment system comprises an equipment shell, a main control unit, a driving assembly and a sterilization assembly. The driving assembly is used for driving blood to flow into the blood storage bag from the blood inlet pipeline and / or flow into the blood transfusion pipeline from the blood storage bag. The sterilization assembly is used for sterilizing blood flowing through the blood inlet pipeline and / or the blood transfusion pipeline; and the main control unit is used for controlling the starting and stopping of the driving assembly and the sterilization assembly and the operation mode of the driving assembly, so that the portability of blood recovery and blood transfusion of a patient suffering from massive hemorrhage in a field environment by medical personnel can be improved, and the survival probability of a wounded person is improved.

A method and system are provided for measuring plasma protein levels in whole blood while a plasma donor is connected to an apheresis machine. A refractometer associated with the apheresis machine is capable of receiving a portion of a disposable tubing set including an integrated cuvette and a prism. The integrated cuvette of the disposable tubing set is inserted into a receiving space of the refractometer associated with the apheresis machine such that a light source and a sensor are precisely aligned and oriented with respect to a sensing surface of the prism and the integrated cuvette. Calibration of the refractometer is performed using an anticoagulant pumped through the disposable tubing set including the integrated cuvette and prism. Based on the light intensity associated with this calibration, the whole blood is measured to determine plasma protein levels and donor eligibility.

During a first stage of a priming procedure, a priming fluid is conveyed into a spinning membrane separator via a filtrate outlet port so as to convey air out of the spinning membrane separator via an inlet port and a retentate outlet port of the spinning membrane separator. During an optional second stage of the priming procedure, the priming fluid is conveyed into the spinning membrane separator via the inlet port so as to convey air out of the spinning membrane separator via the retentate outlet port. A rotor positioned within a housing of the spinning membrane separator may be rotated with respect to the housing during the first and second stages to force air from within the rotor into an annulus defined between the rotor and the housing for more complete priming of the spinning membrane separator.

The present invention discloses an autologous blood collection and recovery machine, including a recovery machine body, a moving mechanism and a stabilizing mechanism. The bottom of the recovery machine body is fixedly connected with a bottom plate, the bottom four corners of the bottom of the bottom plate are fixedly connected with the moving mechanism, and the bottom of the recovery machine body and the right side of the moving mechanism are fixedly connected with the stabilizing mechanism. Through the setting of the moving mechanism, the recovery machine is convenient to move, and it is more stable when moving, and the vibration is reduced. When the moving wheel moves, the vibration generated by the bumps on the road is transmitted through the support rod, the fixed ring vibrates, the fixed block slides on the outer wall of the S-shaped curved rod, the moving sleeve slides on the outer wall of the support rod, the moving rod moves and drives the moving block to move, and squeezes the buffer spring. The sliding column on the top of the moving block slides back and forth at the rotating groove of the outer wall of the rotating column. The elastic ring and the buffer pad play a buffering role, which can effectively prevent excessive vibration from affecting the storage of blood. The shock absorption effect and use effect are good, which improves the practicality of the recovery machine.

The invention discloses a blood component collection and separation device and a use method thereof, relates to the technical field of blood separation, and aims to solve the problems of blood loss, blood volume reduction and leucocyte reduction easily occurring in blood donation. The multi-path box is connected with the needle head assembly, the separation assembly, the air bag, the blood sampling bag and the anticoagulant puncture outfit through pipelines, and the saline puncture outfit is connected with a filter and is connected with the multi-path box through a saline pipeline, so that in-vitro residual blood and human body leucocyte loss after blood donation are reduced, and reduction of the blood volume in a human body is avoided.

A medical contact shock freezer (10, figure 1) for fast freezing a plurality of individual bags containing a medical liquid (e.g. blood plasma) comprises a first pair of freezing plates comprising a f