102 results about "Wound pain" patented technology

An intradermal patch having a permeable backing coated with a polyvinylpyrrolidone-based hydrogel and containing one or more local anesthetics. The patch is breathable, non-irritating upon application and removal, soothing, and sterile. The patch is useful for treating the pain associated with non-intact skin indications.

The invention discloses a medical composite chitosan gel containing medicines promoting wound healing. The medical composite chitosan gel comprises the following compositions in parts by weight: 0.5-10 parts of chitosan high-molecular material, 0.1-8 parts of a medicine promoting wound healing, 0-10 parts of a thickening agent, 1-25 parts of a moisturizing agent, 0-30 parts of a co-solvent/solubilizer, 17-98.4 parts of purified water. The medical composite chitosan gel containing medicines promoting wound healing is capable of effectively keeping the wet environment of a wound, promoting generation of granulation tissue, accelerating wound healing and alleviating wound pain. By employing the chitosan high-molecular material as a matrix and the medicine promoting wound healing as an auxiliary material, the wound dressing combines the advantages that the chitosan high-molecular material is capable of absorbing moisture, keeping moisture, inhibiting bacteria, stopping bleeding and the like and the effect that the medicine promoting wound healing is capable of promoting generation of granulation tissue, accelerating wound healing and alleviating pain, and the gel with excellent performances is prepared.

The present invention provides pharmaceutically acceptable salts having local anesthetic and anti-inflammatory activities. The preferred pharmaceutically acceptable salt is a diclofenac salt of lidocaine. Diclofenac is a non-steroidal anti-inflammatory drug (“NSAID”). Lidocaine is a local anesthetic. Other NSAID (except the salicylic acid derivatives of NSAID) can be used to replace diclofenac and/or other local anesthetics can be used to replace lidocaine. The pharmaceutically acceptable salts are crystalline compounds, which are distinctively different from either the NSAID alone or the local anesthetic alone, as indicated by differential scanning calorimetry (DSC), thermogravimetric analysis (TGA), High Performance Liquid Chromatography (HPLC) and Fourier-Transformed Infrared Spectroscopy (FTIR) analyses. These pharmaceutically acceptable salts are suitable for use in topical treatment or parenteral injection to treat patients with localized pain, including muscle pain, joint pain, pain associated with herpes infection, and wound pain (such as surgical wound, burn wound etc.).

The invention discloses an irradiation crosslinking chitosan/gelatin/polyvinyl alcohol hydrogel dressing as well as a preparation method and an application thereof. The preparation method comprises the steps that a chitosan, gelatin and polyvinyl alcohol solution is prepared by using ultrapure water serving as a solvent; the solution is stirred and mixed uniformly and then irradiated, and original hydrogel is obtained; the original hydrogel is put into the ultrapure water to be soaked; and the chitosan/gelatin/polyvinyl alcohol hydrogel dressing is prepared. The hydrogel dressing is extensive in raw material source, simple in preparation technology and stable in performance, and has the advantages of inflammation diminishing, wound pain relieving, scar reduction, wound healing promotion, wound seepage absorption, and excellent biocompatibility. The hydrogel dressing is easy to degrade after abandoned, and has a smaller influence on an environment. The hydrogel dressing can be applied to the fields of trauma hemostasis, inflammation diminishing, scald, postoperative wound healing and the like.

The invention discloses medical composite chitosan gel containing analgesic drug. The medical composite chitosan gel is prepared from, by weight, 0.5-10 parts of chitosan high molecular materials, 0.5-7 parts of analgesic drug, 0-10 parts of thickening agent, 1-25 parts of moistening agent and 48-98 parts of purified water. The medical composite chitosan gel containing the analgesic drug can effectively keep the wet environment for a wound and relieve wound pain; according to the dressing, the chitosan high molecular materials are used as a matrix, the analgesic drug is adopted in an assisted mode, the advantages of moisture absorption, moisturizing, bacteriostasis, hemostasis and the like and the effect of analgesia of the analgesic drug are combined, and the gel with excellent performance is prepared.

The invention discloses a wound pain quick recovery application instrument, which comprises a body, a controller, a keyboard circuit, an indicator light, a display screen, and three current and voltage regulating circuits, wherein the controller is respectively connected with the keyboard circuit, the display screen, the three current and voltage regulating circuits, a timing circuit and the indicator light; and the output ends of the three current and voltage regulating circuits are respectively connected with three groups of positive and negative electrodes which are respectively connected to three groups of application metal sheets. The wound pain quick recovery application instrument has a reasonable structure, is convenient to use, can form an electric field on the wound surface, accelerates the quick healing of the wound surface, reduces scar tissues, alleviates pain, prevents fat liquoring and postoperative pulmonary embolism, and accelerates the recovery of myoneural junctions.

The invention discloses a stem cell extract product medical dressing, and a preparation method thereof, and belongs to the technical field of biological medicine. The stem cell extract product medicaldressing is a wound cover material with excellent effect, is capable of preventing bacterium infection effectively, accelerating wound healing, controlling and absorbing wound exudate, and protectingnew born tissues, possesses excellent biocompatibility, and is excellent in permeability; no toxic or side effect is caused; natural green raw materials are adopted; the adopted accessory materials are edible grade; too much bleeding and patient pain are avoided; delaying of wound healing caused by left residues is avoided; and an environment beneficial for wound healing is providing for promotion of skin regeneration. The stem cell extract product medical dressing is capable of controlling wound exudates, supplying water and maintaining humidity, relieving inflammation and swelling, relieving wound pain and other discomforts, avoiding scars left by wound, and avoiding influences on skin appearance. The stem cell extract product medical dressing is prepared through freeze drying, so thatit is more beneficial for maintenance of the activity of a large amount of cytokines and proteins, and storage and transportation under room temperature conditions can be realized.

The invention discloses a method for preparing a nano-enzyme-loaded composite nanofiber membrane and a wound dressing. The method for preparing the nano-enzyme-loaded composite nanofiber membrane comprises the steps that (1) 0.1-0.5 part, by weight, of a nanoenzyme is dissolved in 100 parts, by weight, of an aqueous solution of polyvinyl alcohol-acrylamide grafted copolymer with the mass fractionof 5-15% to prepare a spinning solution; (2) the prepared spinning solution is spun into a nanofiber membrane by using an electrostatic spinning method; and (3) and the prepared nanofiber membrane iscross-linked at a temperature of 120 DEG C-150 DEG C for 15-30 min to obtain the nano-enzyme-loaded composite nanofiber membrane. According to the method for preparing the nano-enzyme-loaded compositenanofiber membrane and the wound dressing, the formation of wound crusta can be prevented, newly generated granulation tissue is prevented from sticking, and pain during dressing change is avoided; and the fibrin and necrotic tissue are conveniently dissolved, and the number of changing is reduced; a hypoxic environment is created, and capillary formation is promoted; the release of a variety ofgrowth factors is promoted, and activity is exerted; and wound pain is relieved, and scar formation is reduced.

The invention provides an oxygen release hydrogel dressing. The oxygen release hydrogel dressing is characterized by comprising a first dressing and a second dressing, wherein the first dressing is prepared from a hydrogel dressing body, glucose, an oxygen release catalyst and a polyester mesh sheet having a pore structure, the second dressing comprises a hydrogel dressing body and glucose oxidase, and the first dressing and the second dressing cooperate for use. The oxygen release hydrogel material provided by the invention has good water vapor permeability and good water absorption performance, and a final product can release oxygen, iodine elementary substances and water after being in contact with air, so that the oxygen release hydrogel material as a novel functional material can be used for various acute and chronic wounds, can autonomously remove exudate of damaged tissue, and can guarantee a wet wound environment; and besides, the local oxygen concentration is also increased, anti-inflammatory iodine elementary substances are released, and the oxygen release hydrogel material has the effects of relieving wound pain and accelerating the healing speed of the damaged tissue.

The invention provides a physiotherapy and nursing device for the gynecology and obstetrics department. The problems that in the prior art, when the cold application position is numb, a binding belt needs to be dismantled, and then adjustment can be conducted; and during manual massage, the fatigue is generated, and the strength is uneven are solved. The physiotherapy and nursing device comprisesan arc-shaped shell, a cold application device is mounted on the inner wall of the arc-shaped shell and comprises fixing buckles, connecting plates are mounted on the fixing buckles, belt rollers arerotationally mounted at the other ends of the connecting plates, a cold application belt is connected between the belt rollers, the cold application belt is wound around the belt rollers, an ice bag mounting bag is slidably mounted on the cold application belt, one side of the ice bag mounting bag is connected with a water bag, fixing buckle mounting plates are mounted on the inner wall inside thearc-shaped shell, fixing buckle mounting holes are formed in the fixing buckle mounting plates, the fixing buckles are mounted in the fixing buckle mounting holes, and fixing hooks are mounted at thetop and the bottom of the arc-shaped shell. The position of the ice bag can be adjusted according to the knife edge; when a parturient is subjected to cold application, the waist is massaged by keeping away from a cold application area, and the situation that the cold application device is extruded by a massage device and consequently, a wound pains is avoided; and a heating wire is mounted in the massage device, and meanwhile, the uterus is warmed.

The invention provides a multifunctional liquid band-aid and a preparation method thereof, and relates to the field of medical treatment and public health. The multifunctional liquid band-aid comprises the following raw materials in parts by weight: 5-15 parts of a film-forming material, 0.1-4 parts of a local anesthetic, 0.5-1.5 parts of an antioxidant, 2-15 parts of a plasticizer, 1-20 parts ofa skin emollient, 0.1-1 part of an aromatic agent and 20-85 parts of a fast-drying solvent. The invention has the following characteristics: the prepared liquid band-aid is adhesive, can form a film at the wound quickly, and has excellent waterproofness; the local anesthetic lidocaine and the antioxidant vitamin E play a synergistic role to relieve wound pain, effectively inhibit bacteria and accelerate wound healing; the liquid band-aid is applicable to various complex-shaped wounds and has a certain toughness and permeability; the formed film is transparent and regular so that the wound healing conditions can be observed at any time; and the liquid band-aid provided by the invention has high safety, no toxicity and no obvious skin irritation.

The present invention discloses aseptic sticking membrane agent used for postoperation wound acesodyne, which consists of an anti-sticking layer, a drug-storing layer and a back lining layer. The drug-storing layer consists of framework material and microsphere loaded with local anesthetic, and the framework material is macromolecular polymer with film forming ability. The aseptic sticking membrane agent used for the postoperation wound acesodyne of the present invention can realize the uniform, lasting and slow release of the drug to achieve the lasting acesodyne effect, because the local anesthetic is wrapped inside the microsphere by the micro spheroidization technology. The aseptic sticking membrane agent used for the postoperation wound acesodyne of the present invention is used for the postoperation wound acesodyne, which can ensure that a patient does not have obvious painful feeling during the wound healing period.

The invention discloses a patch instrument for accelerating wound paining curing, comprising a body, a circuit control panel, a keyboard circuit, an indicating lamp, a display screen, a positive electrode and a negative electrode, wherein the body is provided with the keyboard circuit, the display screen and the circuit control panel; the circuit control panel comprises a controller, a current and voltage regulating circuit and a timing circuit; the controller is respectively connected with the keyboard circuit, the display screen, the current and voltage regulating circuit, the timing circuit and the indicating lamp; the output end of the current and voltage regulating circuit is connected with the positive electrode and the negative electrode; and the positive electrode and the negativeelectrode are respectively connected with a metal sheet of a plaster; the plaster is made of spunlace nonwoven, and a patch is arranged in the middle of the inner side of the spunlace nonwoven. The invention has simple structure and convenient use, can form an electric field on a surgical wound surface, promotes the blood circulation, accelerates the curing of wound surfaces and wounds and reduces the scar tissue forming and the paining.

The invention discloses an adjustable medicator for treatment in the department of burn. The adjustable medicator comprises a casing, a drug pipe, a piston, a push rod, an inner container, a support,a micro inflation pump, a micro air suction pump, a first pressure sensor, a control switch, a storage battery, a pipe head and sponge. The adjustable medicator has the advantages that the adjustablemedicator is ingenious in design and has powerful functions; through an electric inflation structure, unguent can be spread on wounds of patients evenly, so that increased workload caused by repeatedwound spreading is avoided effectively, wound pain of the patients due to repeated spreading is reduced, and clinical practicability is extended; the adjustable medicator can fully squeeze the unguentin the drug pipe into the sponge, and accordingly, waste of the unguent is avoided; the pipe head is a detachable structure, so that cross infection can be avoided effectively, and promotion and application in clinical burn treatment are benefited.

The invention belongs to the technical field of biomedical dressings and relates to an end-capped modified polyethylene glycol cross-linking agent having an ultraviolet light response function, a preparation method and a hydrogel dressing containing the cross-linking agent and a preparation method thereof. The technical problem is solved that wound pain and secondary wounds care caused by when anexisting hydrogel dressing is removed for secondary wound treatment. The modified polyethylene glycol cross-linking agent having the ultraviolet light response function is formed by adopting an injectable in-site gel forming mode, and the gel forming mode has very good adaptability to wound shapes and meanwhile has better fitting property compared with a blocky dressing to be gelled without auxiliary fixing materials. When wounds need to be further treated, regional selective irradiation can be performed through 10 mw/cm<2> ultraviolet light of 365 nm, gel softening and degradation are achieved. Compared with other dressings, the function can prevent wound pain during gel removal and prevent newly growing tissues from being physically harmed to cause secondary wounds.

The invention discloses a preparation method of a wound nursing composition after anorectal surgery, in order to solve the problem of treating wound pain after anorectal surgery. The preparation method is characterized by heating tea oil to 200-220 DEG C, feeding the ground Murraya paniculata, Anisodus acutangulus, Spina Gleditsiae, Radix Caulophylli and Herba Portulacae to uniformly mix, heatingfor 10-15 min, filtering oil, heating to 80-100 DEG C, adding colophony powder and Kaolinitum powder, mixing again, spraying cold water to the surface so as to eliminate water toxin after decocting the mixture into a thick paste, and cooling to normal temperature to obtain an ointment. Clinical experiments show that the nursing composition prepared by the method can be utilized to improve local blood circulation, accelerate tissue repair, significantly improve wound healing quality, shorten healing time, and relieve pain after anorectal surgery, and the wound nursing composition is reliable in curative effect and safe to use.

The invention discloses a rehabilitation training pedaling device. The device comprises a fixing mechanism, a pedaling moving mechanism and a resistance adjusting mechanism. The pedaling device is characterized in that the fixing mechanism comprises at least a fixing plate, the pedaling moving mechanism comprises at least a pair of pedals and connecting members which are used for connecting the pedals to make each pair of the pedals perform reverse direction linear motion in which one pedal moves upwards and another pedal moves downwards, the connecting members are used for adjusting the motion resistance of the connecting members to further adjust the connection of the resistance adjusting mechanism of the motion resistance of each pair of the pedals, the resistance adjusting mechanism comprises at least a braking sheet and a resistance controlling device, the braking sheet is in contact with the connecting members, the resistance controlling device is connected with the braking sheet, and the connecting members and the resistance controlling device are fixed on the fixing plate. By means of the pedaling device, the problem of how to reduce the influence on wounds of a patient (such as the causing of wound pain, and wound dehiscence of a postoperative patient can be caused under a severe condition) when the postoperative patient performs lower limb exercising in the prior artis solved.

The invention discloses an antibacterial anti-inflammatory and biomedical dressing for promoting wound healing and a preparation method of the dressing, and belongs to the technical field of medical supplies. The dressing uses a curcumin-containing calcium alginate fiber nonwoven fabric as a skin close layer, the curcumin-containing calcium alginate fiber nonwoven fabric can provide an ideal antibacterial environment for wound healing, promote wound healing, and relieve wound pain; the dressing uses a chitosan fiber non-woven fabric as a middle layer, and the chitosan fiber non-woven fabric has the effects of diminishing inflammation, promoting blood coagulation and inhibiting scars while absorbing exudates; the dressing uses a polyurethane film as an isolation layer, and the polyurethanefilm can achieve the effects of preventing dust, water, air leakage and pollution; and the biomedical dressing prepared by compounding the curcumin-containing calcium alginate fiber nonwoven fabric, the chitosan fiber non-woven fabric and the polyurethane film has complementary and synergistic effects, and the advantages of realizing antibacterial and bacteriostatic properties, a good anti-inflammatory effect and anti-adhesion performance, promoting rapid wound healing and having good biocompatibility. The medical hemostatic dressing provided by the invention has no side effects on human bodies and no any irritation to skin, is safe to use, environmentally friendly and pollution-free, and has wide application prospects in the field of biomedical materials.

The invention provides a traditional Chinese medicine composition as well as a preparation method and application thereof. The traditional Chinese medicine composition is prepared from the following components in parts by weight: 1.3 to 12 parts of plant extract, 0.3 to 1.5 parts of thymol, 0.3 to 3 parts of menthol, and 0.1 to 5 parts of bacteriostatic agent. The traditional Chinese medicine composition has the advantages that the recipe containing the plant extract, the thymol, the menthol and the bacteriostatic agent is reasonable, the components can reach synergistic function, the wound healing is promoted, the swelling of local tissues is reduced, the wound pain is relieved, the oral breath is freshened, the growth of harmful bacteria of escherichia coli, staphylococcus aureus and candida albicans in an oral cavity is inhibited, the cleanliness of the oral cavity is maintained, the uncomfortable symptoms of toothache and the like are relieved, and the market prospect is broad.

The invention provides a wound analgesia slow-release system. The wound analgesia slow-release system comprises a permeable packing block, a catheter, a three-way valve and a free catheter bayonet, wherein the permeable packing block is packed into a wound and can be degraded and absorbed by an organism; the catheter is provided with a packing block mounting end mounted in the permeable packing block and a puncture needle end provided with a puncture needle, and a plurality of side holes are formed in the packing block mounting end; three bayonet ports are formed in the three-way valve, the three bayonet ports are provided with a catheter bayonet, an injector bayonet and a drip tube bayonet respectively, and the outer diameter of the catheter bayonet is designed to be gradually increased from the catheter end to the three-way valve end; the free catheter bayonet comprises a middle connecting plate with a through hole, and a catheter connecting end and an injection interface end which are respectively arranged at two ends of the through hole and communicate with each other. According to the wound analgesia slow-release system provided by the invention, local anesthetic can continuously and evenly permeate into nerve endings inside the wound, wound pain after trauma and an operation is solved, and a painless rehabilitation environment is provided for a patient.

The invention belongs to the field of medicine and particularly relates to a method for constructing a trauma animal model and promoting wound healing. According to the method for promoting wound healing disclosed by the invention, phenytoin silver, dendrobium officinale and hyaluronic acid are utilized as active ingredients to be externally coating a trauma wound, have effects of stopping bleeding, easing pain, relieving itching, restraining wound bacterial infection, promoting wound healing and reducing scar, can be widely applied for treating varieties of traumas like knife wounds, traumatic injury, burn scald, cold injury and the like, can obviously shortens healing time of varieties of trauma wounds, reduces wound pain and itching and reduces scar area.

The invention discloses a wound protection device for the thoracic surgery department, and belongs to the field of medical treatment, the wound protection device comprises a fixed plate, the fixed plate is rotatably connected with a movable plate through a hinge, a fixed frame is arranged at the bottom of the fixed plate, a lifting frame is arranged at the bottom of the end, away from the fixed plate, of the movable plate, and a long groove is formed in the top surface of the movable plate; the device comprises a long groove, box bodies are arranged on the two sides of the long groove, roller bodies are rotationally arranged in the box bodies, the roller bodies are driven by a motor, an adjusting belt is installed on the roller bodies in a winding mode, a protection frame is arranged on the upper side of the long groove, and the protection frame and the upper side part of the adjusting belt are installed. The protection frame and the bed body are integrally designed, when a patient lies on the sickbed, the protection frame is used for supporting the chest of the patient, wound pain caused by the fact that a quilt directly covers the chest of the patient is avoided, meanwhile, the patient is not affected when turning over and shifting, and rehabilitation and nursing of the patient are facilitated.