19 results about "Postoperative Pains" patented technology

The invention discloses a postoperative blackening inhibiting and brightening repairing body lotion and a preparation method thereof, the postoperative blackening inhibiting and brightening repairing body lotion comprises the following components by mass: 1-3% of tranexamic acid, 2-5% of nicotinamide, 3-6% of an aloe vera extract, 0.5-2% of menthol, 0.1-0.5% of an anti-allergy agent, 5-10% of a humectant, 2-4% of an emulsifier, 0.5-1% of a thickener, 0.05-0.2% of a pH regulator, 0.3-0.8% of a preservative, and the balance of deionized water. The invention has the following beneficial effects: by adding tranexamic acid into the formula, the activity of tyrosinase and melanocyte proliferation can be inhibited, melanin generation can be reduced from the source, nicotinamide can block melanin from being transferred to cuticle, and nicotinamide and tranexamic acid generate a synergistic effect, so that the blackness inhibition effect can be enhanced; the anti-inflammatory and moisturizing functions can be provided, then the postoperative skin inflammation reaction is reduced, menthol added in the formula can generate cooling feeling when activated, postoperative pain and scorching discomfort are effectively relieved, and the anti-allergy agent can reduce the skin allergy risk and improve the product safety.

The utility model discloses a kind of postoperative shaping auxiliary devices for neck and back, applied in rehabilitation engineering technical field, including support plate, the top of the support plate is bolted with fixed plate, the top of the front of fixed plate is bolted with adjusting box;The utility model can reduce blood stasis caused by long-term braking by moderate activity design, accelerate inflammation subsides and wound healing, reduce muscle spasm and nerve compression on the basis of maintaining neck physiological curvature, relieve postoperative pain, reduce postoperative muscle fatigue and joint stiffness by dispersing neck pressure, improve patient comfort degree;While maintaining the stability of spine, allow moderate activity, avoid muscle atrophy or joint stiffness caused by long-term complete braking, support device shares back muscle load, relieve postoperative muscle fatigue and spasm caused by compensatory effort, buffer layer reduces the friction of skin and hard brace, reduce the risk of skin damage caused by long-term wearing.

The invention relates to a postoperative anti-regurgitation self-cleaning drainage tube which is suitable for chest drainage after pulmonary lobectomy. In order to solve the problems that a traditional drainage tube depends on gravity to conduct passive drainage, a tube cavity is prone to forming a biological membrane due to sediment to cause blockage and drainage efficiency is insufficient, a plurality of cilia are arranged on the inner wall of a drainage tube body in a surrounding mode in the circumferential direction, the sizes of the cilia are gradually reduced from the root to the top end, and the elasticity modulus is reduced in a gradient mode in the drainage direction; and the vibration device is matched to drive the cilia to swing directionally in the same direction as the drainage direction. According to the design, by simulating the respiratory tract cilia function and utilizing the synergistic effect of cilia structural characteristics and vibration excitation, tube wall sediments are actively and physically stripped, a biological membrane is destroyed to form a foundation, and meanwhile, cilia directionally swings to form drainage auxiliary thrust. According to the application, the occurrence rate of lumen blockage can be obviously reduced, the drainage efficiency is improved, the postoperative pain and medical cost of a patient are reduced, the recovery period is shortened, and the clinical efficient drainage and anti-blockage requirements are met.

This invention discloses the use of Chek2 inhibitors in the preparation of drugs for the prevention and / or treatment of postoperative pain sensitization induced or aggravated by chronic sleep disorders, and its intervention methods, relating to the field of biomedical technology. This invention provides the use of Chek2 inhibitors in the preparation of drugs for the prevention and / or treatment of postoperative pain sensitization induced or aggravated by chronic sleep disorders. This invention is the first to discover and validate Chek2 as a key molecular target linking "chronic sleep disorders" and "postoperative pain sensitization." By constructing a composite animal model of chronic sleep deprivation (CSD) combined with postoperative incision pain, the pathological process of increased postoperative pain in patients with sleep disorders was simulated. Using mRNA-seq and Western blot techniques, this invention is the first to discover and confirm that the expression level of Chek2 in the nucleus accumbens (NAc) brain region is significantly upregulated during postoperative pain sensitization induced by chronic sleep disorders, filling a gap in the field of "sleep disorder-pain interaction" regarding specific central targets.

The utility model discloses a kind of wound decompression nursing pads, including nursing pad main body, nursing pad main body is equipped with the hollow portion for corresponding with wound and the slot for fixing drainage tube, hollow portion is through the upper and lower surfaces of nursing pad main body, slot is set in the upper surface of nursing pad main body.The nursing pad main body of the utility model is equipped with hollow portion, when using, by the hollow portion and the wound of patient corresponding, avoid the wound of patient in body position change or sick lateral decubitus process to be pressed and rub, to avoid appearing wound pain aggravation, ensure that wound tissue has normal healing environment, solve the problem that body position changes difficultly caused by postoperative pain.In addition, the nursing pad main body of the utility model is also equipped with the slot being communicated with hollow portion, the range of activity of drainage tube can be limited by being placed in slot to drainage tube, prevent pipeline from bending when body position changes, ensure the patency of drainage system.

This invention relates to the field of postoperative intelligent analgesia control technology and discloses a postoperative pain prediction and intelligent analgesia drug delivery algorithm system, addressing the technical problems of poor specialist adaptability and delayed intervention in postoperative analgesia management after total hysterectomy. This invention collects specialist characteristics of patients undergoing total hysterectomy, such as menopausal status, pelvic adhesion grade, and gynecologically specific pain types, and performs information entropy weight allocation and fuzzy quantization processing. Standardized features are input into an improved Ornstein-Uhlenbeck process model, which outputs postoperative multi-time-window pain prediction scores. Based on an improved S-shaped maximum effect model combined with gynecological safety hard constraints, personalized drug delivery parameters such as basic infusion rate, single booster dose, and lockout time are generated. A non-singular terminal sliding mode control algorithm drives the analgesia pump to perform precise infusion, and a dual-model decoupled architecture is used to perform closed-loop incremental iteration of the prediction model. This invention can reduce postoperative opioid dosage and control infusion errors within clinically permissible ranges.

The invention relates to the technical field of general surgery department postoperative nursing and intelligent medical auxiliary decision making, in particular to a general surgery department postoperative user pain nursing system and method, and the method comprises the steps: collecting multi-modal sensing data which comprises physiological sign data, behavior characteristic data and environmental parameter data; performing standardization processing and time sequence alignment on the multi-modal sensing data, and constructing a postoperative stress data set; a feature extraction model is utilized, and stress feature vectors comprise autonomic nerve compensation features, mechanical damage stress features and environment induction features; fusing the stress feature vector, and identifying an evolution trajectory of a pain stress shock wave peak; generating a dynamic stress dissipation intervention strategy operation according to the evolution trajectory, wherein the dynamic stress dissipation intervention strategy operation comprises a pharmacological intervention instruction and a non-pharmacological stabilization instruction; correcting the dynamic stress dissipation intervention strategy in real time according to the intervention state fluctuation variance; the method ensures that all intervention actions are accurately deployed before the shock wave peak arrives.

The utility model relates to a connecting rod of a micro-trace spine orthopedic and internal fixation system, which is characterized by comprising a rod body which is connected with a nail seat of an encircling type locking system in a matching way and is used for preventing a ball nail on the nail seat from axially moving, and the rod body comprises a nail seat clamping part and an orthopedic reference part which are connected into a whole along the length direction of the rod body, the top of the shape-righting reference part is provided with a shape-righting reference surface arranged in the axial direction of the shape-righting reference part, and the shape-righting reference surface and the end face of the nail seat after nail locking are kept on the same plane. The connecting rod is used in cooperation with a surrounding type locking nail system, the bending rigidity of the connecting rod can be improved, the torsional rigidity can also be improved, an orthopedic instrument positioning datum plane and an orthopedic loading anchor point can be provided in the spine orthopedic process, the orthopedic position accuracy and the orthopedic efficiency are improved, the incisura after implantation is low, and the orthopedic effect is good. The irritation to surrounding tissues is reduced, and the postoperative pain of a patient is reduced.

The present application relates to a kind of orthopedic implant instruments, including porous layer, porous layer includes variable diameter section, the material of variable diameter section is memory material, so that variable diameter section has original state and deformed state, and variable diameter section can respond to deformation to original state after receiving specific stimulation in deformed state;In deformed state, the surface of porous layer is smooth and the thickness is matched with recipient bone tissue part, and the thickness of variable diameter section is less than original state;By using memory material as variable diameter section, so that in deformed state, orthopedic implant instrument can be directly implanted in corresponding recipient bone tissue part, without the need of tool impact and pressurized implant, reduce the possibility of potential complications and frequent postoperative pain caused by impact and pressurized implant;In addition, after implantation is completed, variable diameter section can respond to special stimulation and deform to original state, and the thickness of variable diameter section increases to realize active pressurization, so that orthopedic implant instrument and recipient bone tissue are fixed by interference fit, so as to achieve better initial stability.

This invention relates to the fields of biomedicine and nanomaterials technology, and provides a bilayer core-shell nanoparticle composite thermosensitive gel for postoperative analgesia, its preparation method, and its applications. The bilayer core-shell nanoparticles comprise: a core of PLGA nanoparticles loaded with magnesium, and a shell of a lipid bilayer loaded with bupivacaine. The composite thermosensitive gel is made by uniformly dispersing the bilayer core-shell nanoparticles in a thermosensitive gel material. By constructing a structure with a lipid shell loaded with bupivacaine and a PLGA core loaded with magnesium, and combining it with a thermosensitive gel, this invention achieves rapid release of bupivacaine for acute postoperative analgesia, and sustained slow release of magnesium ions for long-term anti-inflammatory and repairing effects. This perfectly meets the temporal requirements of postoperative pain management and has broad clinical application prospects.

The invention discloses an application of D-mannose in preparation of a medicine for treating postoperative incision pain, and particularly relates to an application of D-mannose as an effective component in preparation of a local external gel preparation for relieving postoperative pain and promoting wound healing. The invention discloses that D-mannose reduces the expression of proinflammatory factors (such as TNF-alpha, IL-1beta and IL-6) by inhibiting NF-kappa B and MAPK inflammation signal pathways for the first time, so that the dual effects of analgesia and healing promotion are realized. Experiments show that the D-mannose has the optimal effect under the specific concentration (such as 3% w / v), and the D-mannose is high in safety and free of addiction through a local external administration mode. The invention provides a novel, safe and effective non-opioid local treatment choice for postoperative pain management, and has a good clinical application prospect.

This invention discloses a postoperative pain intelligent management system based on multimodal data. The system includes: a data acquisition device for collecting sensor data from multiple modalities of a target patient after gynecological surgery; a data analysis device for analyzing the sensor data according to a preset neural network algorithm to determine the target patient's pain information, pelvic floor exercise information, and current rehabilitation stage, and outputting a corresponding postoperative rehabilitation guidance plan; and a data interaction device connected to the data analysis device and the target patient's mobile device for receiving input data from the target patient or sending the postoperative guidance information to the mobile device for display. Therefore, this invention achieves more automated and efficient postoperative pain monitoring and rehabilitation management, effectively improving the efficiency and effectiveness of postoperative rehabilitation and providing users with more intelligent and comprehensive postoperative rehabilitation services.

The present application relates to the field of orthopedic biomedical technology, specifically, a proximal humerus fracture intramedullary bone cement support rod, which comprises a bone plate, a plurality of first connecting holes and a plurality of second connecting holes are formed on one side of the bone plate, and a solid bone nail is arranged in the first connecting hole. The device can inject bone cement into the bone marrow cavity through the injection channel and the injection port, and then solidify into a rod body to tightly fill the bone marrow cavity space. Through the cooperation of the bone plate and the bone cement support rod in the bone marrow cavity space, a support structure is formed on both sides of the humerus, the stress during the movement of the patient's arm is evenly distributed on both sides of the humerus, the fixation stability is significantly improved, the risk of internal fixation failure such as steel plate displacement and screw cutting is effectively reduced, the bone cement support rod can also prevent the displacement of the fracture block, promote the repair of the fracture, reduce the extrusion and friction of the surrounding tissue of the filling part, reduce the inflammatory reaction and postoperative pain, and improve the comfort of the patient's recovery.

The application discloses a wearable pain relief device and a remote monitoring system thereof, which comprises a multi-modal physiological sensor array, a data fusion processing module, a control module, a transcutaneous electrical stimulation output module, a communication module and a remote monitoring system. The multi-modal sensor array collects pain-related physiological parameters such as electromyography, skin conductance, body surface temperature, heart rate and brain oxygen, the data fusion module generates a pain estimate value, the control module dynamically adjusts the stimulation intensity based on the PID+derivative compensation algorithm, and the transcutaneous electrical stimulation module outputs an electric current to intervene in pain. The communication module uploads data to the remote monitoring system, and medical staff can monitor and remotely adjust parameters in real time through the cloud platform. The application realizes real-time monitoring, intelligent control and remote intervention of pain, has the advantages of personalized treatment, data security and scalability, and is suitable for postoperative pain management, chronic neuropathic pain and the like.

The invention belongs to the technical field of medical instruments in the orthopedics department, and discloses a knee joint revision accessory system and a using method thereof.The knee joint revision accessory system comprises a femoral prosthesis extension rod assembly, a punching guider, a tibia supporting cushion block, a tibia guiding column, a centering drill, a depth limiting sleeve, a supporting platform and a flat head abrasive drill; the thighbone prosthesis extension rod assembly comprises a thighbone prosthesis and a first thighbone extension assembly, through cooperation of a trepanning guider, a centering drill, a depth limiting sleeve and a flat head grinding drill, and through depth limiting design and a guiding function of modular accessories, dependence on experience in an operation is reduced, accuracy of the implant position and depth of the prosthesis is ensured, deviation risks are reduced, and operation efficiency is improved. The tibial plateau supporting condition is improved through leveling treatment of the supporting cushion block and the flat head abrasive drill, in the 1.5-stage operation, periprosthetic joint infection, conversion operation and dislocation are low, prosthesis instability caused by bone defects is avoided, meanwhile, accurate bone treatment and stable prosthesis implantation are achieved, and the possibility of postoperative pain or infection or secondary revision is reduced.

The invention discloses a composition for treating tonsil after low-temperature plasma resection operation as well as a preparation method and application of the composition. The composition is prepared from 12 traditional Chinese medicines including honeysuckle, plantain herb, radix scutellariae, radix rehmanniae recen, cortex moutan, radix paeoniae rubra, radix angelicae, nidus vespae, angelica sinensis, rhizoma corydalis, radix adenophorae and liquorice, and is prepared by the following steps: washing the traditional Chinese medicines, chopping, soaking in a proper amount of water, decocting, filtering, heating and concentrating filtrate, standing at room temperature, cooling, filtering by a filter membrane for sterilization, and adding conventional pharmaceutic adjuvants to prepare corresponding dosage forms. The traditional Chinese medicine composition can be used for low-temperature plasma postoperative treatment of obstructive sleep apnea syndrome tonsil, can effectively relieve postoperative pain symptoms, can effectively promote soft palate edema regression, and can promote formation of healthy white membranes on wound surfaces.