43 results about "Postoperative Pains" patented technology

The invention discloses a multi-mode postoperative child pain identification method. The method aims at improving the accuracy of child postoperative pain recognition by fusing ECG (electrocardiogram), SPO2 (blood oxygen) and EEG (electroencephalogram) multi-mode data. The method comprises the following steps of: firstly, respectively acquiring and preprocessing each modal data, and converting EEG (electroencephalogram) into two types of two-dimensional frames; then, feature extraction is automatically conducted on the data of all the modes through specific neural networks including the frequency domain flow neural network, the time domain flow neural network, the oxyhemoglobin saturation CNN-GRU neural network and the electrocardio CNN-GRU neural network; and finally, inputting the extracted features into an MLP feature fusion layer to carry out pain identification. Compared with a traditional single-mode identification method, the postoperative child pain related characteristics can be more comprehensively captured, the pain identification accuracy is effectively improved, and powerful support is provided for medical staff to accurately evaluate the postoperative child pain degree in time.

The invention discloses an intelligent drug delivery pain management bracelet, and relates to the fields of wearable equipment, transdermal drug delivery and biological signal processing. The bracelet is integrated with a multi-mode biosensor which comprises a temperature sensor, a pressure sensor, a heart rate sensor, a blood oxygen sensor and a skin electric response sensor, and physiological data related to pain can be collected in real time. Through an embedded microcontroller and a machine learning algorithm, a pain intensity evaluation model is constructed, and real-time evaluation of the pain state of a patient is realized. Based on the pain intensity and the physiological state of a patient, a drug release strategy is dynamically adjusted through an intelligent algorithm, and drugs are released painlessly and accurately through a micro-needle transdermal drug delivery technology, so that the patient obtains the optimal treatment effect. And the functions of data storage, historical analysis and remote doctor monitoring can be expanded. The hand ring is convenient to operate, comfortable to use and suitable for various pain management scenes such as chronic pain and postoperative pain, and the personalized level of pain treatment and patient compliance are remarkably improved.

The invention discloses a postoperative pain degree sensor and an ovum extraction operation pain monitoring system, and belongs to the field of postoperative health monitoring and intelligent nursing equipment. The sensor comprises a flexible substrate, and a skin electric response sensing unit, a temperature sensing unit, a myoelectricity sensing unit, a micro-pressure sensing unit, a signal processing circuit and a wireless communication module which are integrated on the flexible substrate, the monitoring system comprises an edge processing module, a pain index evaluation module, an interaction terminal and a data recording module. The system evaluates the postoperative pain level based on the multi-channel physiological signals, real-time quantification and alarm prompt of the pain state are achieved, and the postoperative nursing response efficiency is improved. The scheme is suitable for assisting pain management after reproductive ovum extraction, and has the advantages of high sensitivity, low delay, structural flexibility and system closed loop.

The invention discloses an orthopedic postoperative rehabilitation node prediction method based on an improved ant colony algorithm. The method comprises the following steps: S1, extracting postoperative pain level features, limb function recovery progress features and exercise ability evaluation data features of a postoperative patient; s2, generating a standardized postoperative patient feature data set; s3, generating a weight matrix containing each feature weight; s4, initializing parameters of the improved ant colony algorithm based on the standardized feature data set and the weight matrix of the postoperative patient; s5, performing path search on the postoperative rehabilitation nodes by adopting an improved ant colony algorithm; s6, taking the result of the improved ant colony algorithm path search as the prediction result of the postoperative rehabilitation node; and S7, generating a postoperative rehabilitation plan of the patient based on a prediction result. According to the method, obvious improvement is achieved in orthopedic postoperative rehabilitation node prediction, the rehabilitation efficiency of a patient can be effectively improved, and the recurrence risk is reduced.

The present invention discloses a nutritional paste and a preparation method thereof, and belongs to the technical field of animal feed preparation, the nutritional paste comprises a plurality of components, the eucommia ulmoides extract has good anti-inflammatory, analgesic and anti-stress effects, can relieve pain and inflammation after dogs and cats are sterilized, and can be used for preparing the nutritional paste for dogs and cats. And the astragalus extract (containing astragalus polysaccharide) has the effect of enhancing the immunity of the organism, so that the postoperative complications of dogs and cats after sterilization can be effectively prevented. The semen ziziphi spinosae, the gamma-aminobutyric acid and the tryptophan have the effects of calming and relieving restlessness, the lactoferrin can assist iron absorption and assist hematogenesis, meanwhile, the glutamine can promote wound healing, and the prebiotics can adjust intestinal flora imbalance caused by stress and use of antibiotics, so that postoperative gastrointestinal discomfort is avoided. The nutritional paste prepared by the invention can guarantee nutrient substances required by pet dogs and cats in the postoperative stage, promote wound healing of the pet dogs and cats after the operation, effectively relieve postoperative pain and restlessness, enhance the immunity of the organism and promote rapid recovery after the operation.

The invention provides a traditional Chinese medicine hot compress bag for relieving endoscopic postoperative pain and a preparation method of the traditional Chinese medicine hot compress bag, and belongs to the technical field of traditional Chinese medicine hot compress bags. The invention provides a traditional Chinese medicine composition for regulating spleen and stomach and activating meridians to stop pain. The traditional Chinese medicine composition is prepared from the following raw materials in parts by weight: 70 to 100 parts of liquorice root, 20 to 80 parts of rhizoma zingiberis, 20 to 80 parts of fructus evodiae, 20 to 80 parts of semen raphani, 20 to 80 parts of malt, 20 to 50 parts of cassia twig, 20 to 50 parts of fructus perillae and 10 to 30 parts of black prepared common monkshood daughter root. The traditional Chinese medicine composition provided by the invention has remarkable effects of regulating spleen and stomach and activating meridians to stop pain, and can play roles of astringing and inducing astringency, tonifying middle-Jiao and Qi, and dispersing blood stasis and relieving pain after being prepared into a traditional Chinese medicine Reyan bag. Due to the design of the self-heating device, the heating time of the traditional Chinese medicine hot compress bag is long, the heating power maintaining time is long, transdermal absorption of medicines in the traditional Chinese medicine hot compress bag is facilitated, and the pain after the endoscopic surgery can be remarkably relieved.

This application relates to the technical field of medical devices, and particularly to an artificial knee joint prosthesis. An artificial knee joint prosthesis includes: a tibial tray; a liner mounted on the tibial tray; a femoral condyle prosthesis, which includes a femoral condyle metal component and a femoral condyle ceramic component. The femoral condyle ceramic component covers the outer wall of the femoral condyle metal component. The femoral condyle ceramic component is in sliding fit with the liner. The inner wall of the femoral condyle metal component is a 3D printed trabecular bone structure, which can achieve biological fixation and bone ingrowth. This application has the effect of reducing the friction between the liner and the femoral condyle prosthesis, reducing the particles generated by polyethylene wear, thereby reducing the occurrence of inflammation in patients, avoiding bone cement reactions, and reducing the occurrence of postoperative pain and joint instability in patients.

The invention provides an injection capable of treating various cancerous pains and postoperative pains and a preparation method of the injection, and relates to the technical field of pharmaceutical preparations. The preparation method comprises the following steps: filling nitrogen into water for injection at the temperature of 30-60 DEG C, sequentially adding sodium chloride, citric acid and sodium citrate according to a preparation amount, stirring to dissolve the sodium chloride, the citric acid and the sodium citrate, then adding butorphanol tartrate according to a preparation amount, and stirring until the butorphanol tartrate is completely dissolved for later use. According to the preparation method of the butorphinol tartrate injection provided by the invention, the technological parameters are accurately controlled, and the reference preparation prescription of the butorphinol tartrate injection does not need to be changed, so that the sterile guarantee level of the butorphinol tartrate injection can be improved, the increase of the impurity content can be effectively controlled, and the good stability of the butorphinol tartrate injection is ensured.

The invention relates to the technical field of pharmaceutical preparations, and particularly discloses an arginine ibuprofen biphasic sustained release preparation and a preparation method thereof. Through a two-phase system of quick-release particles and slow-release particles, the problems that a traditional preparation takes effect slowly, is short in medicine effect and poor in taste are solved. Wherein the quick-release granules are prepared by mixing and granulating ibuprofen arginine, a filling agent, an adhesive and a natural flavoring agent, so that the effective blood concentration can be ensured to be reached within 15 minutes after the medicine is orally taken so as to quickly relieve pain, and the bad flavor of the medicine can be synchronously covered; the sustained-release granules are based on an ibuprofen arginine drug-loading core, the outer layer of the sustained-release granules is coated with a sustained-release film formed by a sustained-release agent and a plasticizer, and the effective blood concentration can be stably maintained for 6-8 hours, so that the medicine taking frequency is reduced, the sustained-release granules only need to be taken for 1-2 times every day, the medication compliance of a patient is greatly improved, and the sustained-release granules are suitable for clinical application. The traditional Chinese medicine composition is especially suitable for clinical scenes needing long-term or repeated analgesia such as chronic arthritis and postoperative pain, has excellent safety and practicability, and has a wide market application prospect.

The invention discloses a postoperative blackening inhibiting and brightening repairing body lotion and a preparation method thereof, the postoperative blackening inhibiting and brightening repairing body lotion comprises the following components by mass: 1-3% of tranexamic acid, 2-5% of nicotinamide, 3-6% of an aloe vera extract, 0.5-2% of menthol, 0.1-0.5% of an anti-allergy agent, 5-10% of a humectant, 2-4% of an emulsifier, 0.5-1% of a thickener, 0.05-0.2% of a pH regulator, 0.3-0.8% of a preservative, and the balance of deionized water. The invention has the following beneficial effects: by adding tranexamic acid into the formula, the activity of tyrosinase and melanocyte proliferation can be inhibited, melanin generation can be reduced from the source, nicotinamide can block melanin from being transferred to cuticle, and nicotinamide and tranexamic acid generate a synergistic effect, so that the blackness inhibition effect can be enhanced; the anti-inflammatory and moisturizing functions can be provided, then the postoperative skin inflammation reaction is reduced, menthol added in the formula can generate cooling feeling when activated, postoperative pain and scorching discomfort are effectively relieved, and the anti-allergy agent can reduce the skin allergy risk and improve the product safety.

The invention discloses a tibial prosthesis and a knee joint prosthesis with the tibial prosthesis. The tibial prosthesis comprises a patellar ligament attachment surface, a lateral collateral ligament attachment surface and a medial collateral ligament attachment surface, and the surface roughness of at least one of the patellar ligament attachment surface, the lateral collateral ligament attachment surface and the medial collateral ligament attachment surface is smaller than or equal to a preset value. The tibia prosthesis has the advantages of being small in friction, low in abrasion, free of inflammatory response and pain, capable of remarkably reducing postoperative pain and discomfort, beneficial to recovery of patients, capable of effectively maintaining stability and functions of knee joints, long in service life and the like.

The invention belongs to the field of traditional Chinese medicines, and particularly relates to a traditional Chinese medicine externally-applied ointment for treating postoperative complications of mixed hemorrhoids as well as a preparation method and application of the traditional Chinese medicine externally-applied ointment. The externally-applied traditional Chinese medicine ointment for treating postoperative complications of mixed hemorrhoids comprises the following raw materials in parts by weight: 150-250 parts of calcined gypsum, 27-45 parts of bryozoatum, 9-15 parts of indigo naturalis, 36-60 parts of borneol, 30-60 parts of sesame oil and 500-850 parts of vaseline, has the effects of clearing heat and promoting diuresis, relieving swelling and pain, and healing sores and stopping bleeding, can treat main symptoms after the mixed hemorrhoids, and has no toxic or side effects. Complications such as postoperative pain, wound edema, anal pendant expansion, bleeding and the like are effectively relieved, and wound healing is accelerated.

The utility model discloses a kind of postoperative shaping auxiliary devices for neck and back, applied in rehabilitation engineering technical field, including support plate, the top of the support plate is bolted with fixed plate, the top of the front of fixed plate is bolted with adjusting box;The utility model can reduce blood stasis caused by long-term braking by moderate activity design, accelerate inflammation subsides and wound healing, reduce muscle spasm and nerve compression on the basis of maintaining neck physiological curvature, relieve postoperative pain, reduce postoperative muscle fatigue and joint stiffness by dispersing neck pressure, improve patient comfort degree;While maintaining the stability of spine, allow moderate activity, avoid muscle atrophy or joint stiffness caused by long-term complete braking, support device shares back muscle load, relieve postoperative muscle fatigue and spasm caused by compensatory effort, buffer layer reduces the friction of skin and hard brace, reduce the risk of skin damage caused by long-term wearing.

The utility model discloses an assessment ruler for postoperative active pain, which relates to the technical field of pain assessment tools, and comprises an assessment ruler main body, one side of the assessment ruler main body is provided with an NRS pain score indication line, the surface of the NRS pain score indication line is provided with a plurality of first lamp bodies, and the first lamp bodies are provided with second lamp bodies. A plurality of first control buttons matched with the first lamp bodies are arranged above the NRS pain score indication line. According to the utility model, the positions of the first indicator and the second indicator are moved, so that the first control button and the second control button which correspond to each other are pressed, the first lamp body and the second lamp body which correspond to each other are lightened, and the voice output device synchronously broadcasts the contents of the NRS pain level and the FAS pain level which reach the positions; according to the design, the postoperative active pain assessment process of the patient can be quicker and more efficient, the patient can express own pain feeling more accurately, and assessment errors caused by unsmooth communication or understanding deviation are reduced.

The invention relates to a postoperative anti-regurgitation self-cleaning drainage tube which is suitable for chest drainage after pulmonary lobectomy. In order to solve the problems that a traditional drainage tube depends on gravity to conduct passive drainage, a tube cavity is prone to forming a biological membrane due to sediment to cause blockage and drainage efficiency is insufficient, a plurality of cilia are arranged on the inner wall of a drainage tube body in a surrounding mode in the circumferential direction, the sizes of the cilia are gradually reduced from the root to the top end, and the elasticity modulus is reduced in a gradient mode in the drainage direction; and the vibration device is matched to drive the cilia to swing directionally in the same direction as the drainage direction. According to the design, by simulating the respiratory tract cilia function and utilizing the synergistic effect of cilia structural characteristics and vibration excitation, tube wall sediments are actively and physically stripped, a biological membrane is destroyed to form a foundation, and meanwhile, cilia directionally swings to form drainage auxiliary thrust. According to the application, the occurrence rate of lumen blockage can be obviously reduced, the drainage efficiency is improved, the postoperative pain and medical cost of a patient are reduced, the recovery period is shortened, and the clinical efficient drainage and anti-blockage requirements are met.

This invention discloses the use of Chek2 inhibitors in the preparation of drugs for the prevention and / or treatment of postoperative pain sensitization induced or aggravated by chronic sleep disorders, and its intervention methods, relating to the field of biomedical technology. This invention provides the use of Chek2 inhibitors in the preparation of drugs for the prevention and / or treatment of postoperative pain sensitization induced or aggravated by chronic sleep disorders. This invention is the first to discover and validate Chek2 as a key molecular target linking "chronic sleep disorders" and "postoperative pain sensitization." By constructing a composite animal model of chronic sleep deprivation (CSD) combined with postoperative incision pain, the pathological process of increased postoperative pain in patients with sleep disorders was simulated. Using mRNA-seq and Western blot techniques, this invention is the first to discover and confirm that the expression level of Chek2 in the nucleus accumbens (NAc) brain region is significantly upregulated during postoperative pain sensitization induced by chronic sleep disorders, filling a gap in the field of "sleep disorder-pain interaction" regarding specific central targets.

The invention discloses a thoracic postoperative neuropathic pain risk prediction method and system based on machine learning, and relates to the technical field of medical information. According to the method, multiple advanced machine learning models and optimization technologies are comprehensively applied, so that the accuracy of postoperative neuropathic pain risk prediction is remarkably improved; pain data at multiple time points before operation, during operation and after operation are comprehensively considered, dynamic updating and iterative prediction can be achieved, and postoperative analgesia management is optimized in time; a set of complete automatic solution is provided, whole-process systematization of data acquisition, risk prediction and result judgment is realized, and powerful data support is provided for clinical decision making. The combination of the method and the system not only improves the accuracy and reliability of prediction, but also optimizes the postoperative pain management, and improves the postoperative life quality of the patient.

The utility model relates to the technical field of medical instruments, in particular to a fracture minimally invasive internal fixation guiding device which comprises a fixing plate, a positioning plate, a clamping mechanism and a sleeve, a plurality of sets of fixing holes are formed in the fixing plate in a penetrating mode, a plurality of sets of positioning holes are formed in the positioning plate in a penetrating mode, and the positioning holes correspond to the fixing holes. The clamping mechanism comprises a clamping plate, a plurality of sets of clamping bases are arranged on the clamping plate in a sliding mode, and a needle hole is formed in the sleeve in a penetrating mode. The positioning plate is used for guiding, a smaller incision can be realized, so that the postoperative pain and trauma are reduced, the minimally invasive property of the surgery is improved, the concept of'minimally invasive, painless and rapid rehabilitation 'pursued by the modern surgery is met, and the minimally invasive property is stronger.

The utility model discloses a kind of wound decompression nursing pads, including nursing pad main body, nursing pad main body is equipped with the hollow portion for corresponding with wound and the slot for fixing drainage tube, hollow portion is through the upper and lower surfaces of nursing pad main body, slot is set in the upper surface of nursing pad main body.The nursing pad main body of the utility model is equipped with hollow portion, when using, by the hollow portion and the wound of patient corresponding, avoid the wound of patient in body position change or sick lateral decubitus process to be pressed and rub, to avoid appearing wound pain aggravation, ensure that wound tissue has normal healing environment, solve the problem that body position changes difficultly caused by postoperative pain.In addition, the nursing pad main body of the utility model is also equipped with the slot being communicated with hollow portion, the range of activity of drainage tube can be limited by being placed in slot to drainage tube, prevent pipeline from bending when body position changes, ensure the patency of drainage system.

The utility model discloses a rigid expander which comprises an inner tube and an outer tube which are sleeved together in a clearance mode, a threaded rod is arranged at the rear end of the inner tube, a handle ring capable of rotating freely is sleeved at the rear end of the outer tube in a limiting mode, and internal threads matched with the threaded rod are arranged on the inner side of the handle ring. A plurality of blades are movably arranged in the circumferential direction between the front end of the inner pipe and the front end of the outer pipe, and when the inner pipe and the outer pipe generate axial relative displacement, the blades expand in the radial direction or close in the radial direction; according to the scheme, the front end of the spine dilator can conduct radial dilation, so that soft tissue blocking the operation visual field in the channel is pushed aside, medical staff do not need to spend a large amount of time to clean the soft tissue blocking the visual field, the operation difficulty is lowered, the operation efficiency is improved, and postoperative pain caused by unnecessary soft tissue cleaning is reduced.

This invention relates to the field of postoperative intelligent analgesia control technology and discloses a postoperative pain prediction and intelligent analgesia drug delivery algorithm system, addressing the technical problems of poor specialist adaptability and delayed intervention in postoperative analgesia management after total hysterectomy. This invention collects specialist characteristics of patients undergoing total hysterectomy, such as menopausal status, pelvic adhesion grade, and gynecologically specific pain types, and performs information entropy weight allocation and fuzzy quantization processing. Standardized features are input into an improved Ornstein-Uhlenbeck process model, which outputs postoperative multi-time-window pain prediction scores. Based on an improved S-shaped maximum effect model combined with gynecological safety hard constraints, personalized drug delivery parameters such as basic infusion rate, single booster dose, and lockout time are generated. A non-singular terminal sliding mode control algorithm drives the analgesia pump to perform precise infusion, and a dual-model decoupled architecture is used to perform closed-loop incremental iteration of the prediction model. This invention can reduce postoperative opioid dosage and control infusion errors within clinically permissible ranges.

The invention relates to the technical field of medical instruments, in particular to colorectal cancer postoperative rehabilitation intelligent wearable equipment which comprises an air bag watchband, a fixing frame is arranged on the air bag watchband, and a magnetic attraction assembly and a monitoring assembly are arranged on the air bag watchband; a display assembly and an energy supply assembly are arranged on the fixed frame; limiting frames are symmetrically arranged in the fixing frame, a driving piece is arranged in the fixing frame, a center connecting rod is arranged on an output shaft of the driving piece, first connecting rods are arranged at the two ends of the center connecting rod, second connecting rods are symmetrically arranged on the two sides of the center connecting rod, the two ends of each second connecting rod are hinged to the adjacent first connecting rods, and first massage assemblies are arranged on the first connecting rods. The first massage assembly comprises a third connecting rod, and a massage rod and a first massage ball are sequentially arranged on the third connecting rod; second massage assemblies are arranged on the second connecting rods; a heat dissipation assembly is arranged on an output shaft of the driving piece. By means of the first massage assembly and the second massage assembly, multiple massage on the wrist of a patient is achieved, postoperative pain of the patient is relieved, and the comfort level of the patient is improved.

The invention discloses a postoperative pain monitoring method based on a wearable flexible sensor, and relates to the technical field of postoperative pain monitoring. According to the method, a postoperative pain monitoring model mapping relation is constructed based on patient basic feature data in a patient information database, and a corresponding postoperative pain monitoring model is determined based on the postoperative pain monitoring model mapping relation; patient pain feature data of a postoperative patient is input into a postoperative pain monitoring model, pain level monitoring is performed, a postoperative pain monitoring model mapping relation is constructed by integrating historical patient physiological data and individual features, and a dual mechanism of rapid screening of a first classification model and accurate verification of a secondary multimode monitoring model is adopted. According to the invention, the method achieves the grading monitoring of the pain grade of a postoperative patient, enhances the adaptability to different patient groups based on the model adaptation of individual features, and solves the problems that the existing postoperative pain monitoring method is too limited in single-mode evaluation, and is insufficient in individual difference adaptability.

The invention discloses a surgical beauty suturing device, and relates to the technical field of medical instruments, the surgical beauty suturing device comprises a needle frame and a suturing needle, the tail end of the suturing needle is provided with a suturing thread in a penetrating manner, the front and rear ends of the needle frame are provided with needle tube sleeves, the needle tube sleeves are used for clamping the suturing needle, and the inner side walls of the needle tube sleeves are matched with the needle body of the suturing needle in shape; an opening is formed in the side of the needle tube sleeve, a driving roller is correspondingly arranged on the outer side of the opening, and the driving roller is pressed on the suture needle in the needle tube sleeve and provides rotation power for the suture needle. The surgical beauty suture auxiliary device assists a doctor in performing surgical beauty suture operation on a wounded person, the suture precision and consistency can be remarkably improved, human errors are reduced, the operation efficiency is improved, the infection risk is reduced, and meanwhile postoperative pain and complications of a patient are reduced. Through accurate control of the device, the device can provide a high-standard, repeatable and standardized suturing effect, and is particularly beneficial to complex and high-requirement cosmetic surgery.

The invention provides a female private plastic post-operation protector based on medical cosmetology, comprising a protective pad which is made of a soft and breathable material, has a shape of a sanitary pad structure, and is used for fitting a post-operation part and providing comfortable support; the cooling module is arranged in the protective pad and used for relieving postoperative local edema and pain through low temperature; the compression module is arranged on the upper surface wall of the protective pad and used for reducing accumulation of local blood and lymph through moderate compression, the compression module can change the acting force of the compression module so as to change the compression strength, and the outer surface wall of the protective pad is sleeved with a detachable protective film so that sanitation and safety can be guaranteed; through compression and cooling functions, postoperative local edema is effectively reduced, postoperative pain is relieved, wound healing is promoted, and the overall satisfaction degree of a patient is improved.

The application discloses a postoperative children's pain recognition method based on an interpretable prototype, aiming to improve the interpretability of postoperative children's pain detection by comparing the similarity of facial feature positions. First, facial expression frames and sparse optical flow frames of each frame of picture are extracted from postoperative children's pain videos. Then, the feature vector of the facial feature position is extracted by using the ResNet convolution network, and the randomly initialized prototype vector is optimized by minimizing the loss function. Then, the similarity of the feature vector and the prototype vector is calculated, and the pain level recognition result of each frame of picture is obtained through the full connection network. Finally, the facial feature positions corresponding to the feature vector and the facial feature positions corresponding to the prototype vector are visually compared. The application improves the interpretability of the postoperative children's pain recognition process by showing the similarity of the facial feature positions on the facial expression and the sparse optical flow, which helps medical professionals better understand the automatic pain recognition result.

The invention relates to the technical field of general surgery department postoperative nursing and intelligent medical auxiliary decision making, in particular to a general surgery department postoperative user pain nursing system and method, and the method comprises the steps: collecting multi-modal sensing data which comprises physiological sign data, behavior characteristic data and environmental parameter data; performing standardization processing and time sequence alignment on the multi-modal sensing data, and constructing a postoperative stress data set; a feature extraction model is utilized, and stress feature vectors comprise autonomic nerve compensation features, mechanical damage stress features and environment induction features; fusing the stress feature vector, and identifying an evolution trajectory of a pain stress shock wave peak; generating a dynamic stress dissipation intervention strategy operation according to the evolution trajectory, wherein the dynamic stress dissipation intervention strategy operation comprises a pharmacological intervention instruction and a non-pharmacological stabilization instruction; correcting the dynamic stress dissipation intervention strategy in real time according to the intervention state fluctuation variance; the method ensures that all intervention actions are accurately deployed before the shock wave peak arrives.

The utility model relates to a connecting rod of a micro-trace spine orthopedic and internal fixation system, which is characterized by comprising a rod body which is connected with a nail seat of an encircling type locking system in a matching way and is used for preventing a ball nail on the nail seat from axially moving, and the rod body comprises a nail seat clamping part and an orthopedic reference part which are connected into a whole along the length direction of the rod body, the top of the shape-righting reference part is provided with a shape-righting reference surface arranged in the axial direction of the shape-righting reference part, and the shape-righting reference surface and the end face of the nail seat after nail locking are kept on the same plane. The connecting rod is used in cooperation with a surrounding type locking nail system, the bending rigidity of the connecting rod can be improved, the torsional rigidity can also be improved, an orthopedic instrument positioning datum plane and an orthopedic loading anchor point can be provided in the spine orthopedic process, the orthopedic position accuracy and the orthopedic efficiency are improved, the incisura after implantation is low, and the orthopedic effect is good. The irritation to surrounding tissues is reduced, and the postoperative pain of a patient is reduced.

The present application relates to a kind of orthopedic implant instruments, including porous layer, porous layer includes variable diameter section, the material of variable diameter section is memory material, so that variable diameter section has original state and deformed state, and variable diameter section can respond to deformation to original state after receiving specific stimulation in deformed state;In deformed state, the surface of porous layer is smooth and the thickness is matched with recipient bone tissue part, and the thickness of variable diameter section is less than original state;By using memory material as variable diameter section, so that in deformed state, orthopedic implant instrument can be directly implanted in corresponding recipient bone tissue part, without the need of tool impact and pressurized implant, reduce the possibility of potential complications and frequent postoperative pain caused by impact and pressurized implant;In addition, after implantation is completed, variable diameter section can respond to special stimulation and deform to original state, and the thickness of variable diameter section increases to realize active pressurization, so that orthopedic implant instrument and recipient bone tissue are fixed by interference fit, so as to achieve better initial stability.

This invention relates to the fields of biomedicine and nanomaterials technology, and provides a bilayer core-shell nanoparticle composite thermosensitive gel for postoperative analgesia, its preparation method, and its applications. The bilayer core-shell nanoparticles comprise: a core of PLGA nanoparticles loaded with magnesium, and a shell of a lipid bilayer loaded with bupivacaine. The composite thermosensitive gel is made by uniformly dispersing the bilayer core-shell nanoparticles in a thermosensitive gel material. By constructing a structure with a lipid shell loaded with bupivacaine and a PLGA core loaded with magnesium, and combining it with a thermosensitive gel, this invention achieves rapid release of bupivacaine for acute postoperative analgesia, and sustained slow release of magnesium ions for long-term anti-inflammatory and repairing effects. This perfectly meets the temporal requirements of postoperative pain management and has broad clinical application prospects.