108 results about "Sleep deprivation" patented technology

Visual methods and systems are described for detecting alertness and vigilance of persons under conditions of fatigue, lack of sleep, and exposure to mind altering substances such as alcohol and drugs. In particular, the intention can have particular applications for truck drivers, bus drivers, train operators, pilots and watercraft controllers and stationary heavy equipment operators, and students and employees during either daytime or nighttime conditions. The invention robustly tracks a person's head and facial features with a single on-board camera with a fully automatic system, that can initialize automatically, and can reinitialize when it need's to and provide outputs in realtime. The system can classify rotation in all viewing direction, detects' eye/mouth occlusion, detects' eye blinking, and recovers the 3D(three dimensional) gaze of the eyes. In addition, the system is able to track both through occlusion like eye blinking and also through occlusion like rotation. Outputs can be visual and sound alarms to the driver directly. Additional outputs can slow down the vehicle cause and/or cause the vehicle to come to a full stop. Further outputs can send data on driver, operator, student and employee vigilance to remote locales as needed for alarms and initiating other actions.

An efficient, objective, flexible and easily deployable system for conducting evaluations of mental and physiological state and recommending individualized treatment to improve said state is described. The method and system are based on commensurate measurement of mental functions, levels of stress and anxiety, and/or biologically active molecules such as neurotransmitters, immune markers including cytokines and hormones. The method and system are designed to assess an individual's cognitive function and the underlying physiology in order to delineate various disease processes, injuries, drug states, training stages, fatigue levels, stress levels, aging processes, predict susceptibility to stress and/or sleep deprivation, identify aptitude for training and/or characterize effects of any experimental conditions. The system and method may be used in recommending individualized treatment protocols, as well as to guide the treatment process by assessing the efficacy of such therapies in the clinical trials process.

This document provides systems and methods for testing and assessing cognitive performance of a user over a period of time in order to test environmental effects and other factors on the performance of the user. For example, cognitive performance over a period of time can be assessed for users experiencing stress conditions including hypoxia (oxygen deprivation), hypothermia, sleep deprivation, fatigue or other factors that may cause degradation in cognitive performance. Furthermore, the systems and methods described herein can be used to identify when hypoxia has manifested in the cerebral circulation of an individual rather than merely in the extremities of an individual.

The present invention is directed to a method of continuously monitoring neuronal avalanches in a subject comprising (a) determining a deviation in avalanche exponent (α) or branching parameter (σ) from a predetermined value at rest, wherein the pre-determined value of α is a slope of a size distribution of the synchronized neuronal activity and the predetermined value is −3/2 and the pre-determined value of σ is a ratio of successively propagated synchronized neuronal activity and the predetermined value is 1; and (b) repeating step (a) one or more times to continuously monitor neuronal avalanches in a subject. The invention also features methods of determining or monitoring the degree of sleep deprivation in a subject, methods of identifying subjects that are susceptible to a sleep disorder and methods of diagnosing a sleep disorder in a subject.

The present invention is directed to a method of continuously monitoring neuronal synchronization in a subject comprising (a) determining a deviation in mean synchronization (R) from a predetermined value at rest, wherein the pre-determined value of R is 1, and the variability of synchronization H; and (b) repeating step (a) one or more times to continuously monitor synchronization R and its variability H in a subject. The invention also features methods of determining and monitoring the degree of brain excitability. The invention furthermore features methods of determining or monitoring the degree of sleep deprivation in a subject, methods of identifying subjects that are susceptible to a sleep disorder and methods of diagnosing a sleep disorder in a subject.

The invention relates to a mask, and especially relates to a mask having moisturizing and anti-oxidation functions, and its making method. The mask is obtained through using the following raw materials, by weight, 10-20 parts of ginkgo leaf, 15-25 parts of aloe, 5-15 parts of pawpaw, 10-20 parts of chrysanthemum, 5-15 parts of licorice, and 5-15 parts of Lophatherum gracile. The mask having the advantages of scientific and reasonable formula, easily available raw materials, low price, supplementation of abundant natural vitamins for skins, skin pigment removal, prevention of oxidizing damages comprising ultraviolet ray damage, anti-ageing, increase of the skin elasticity, helpfulness for the increase of the immunization and protection effects of skins, restoration of black spots caused by sun exposure and sleep insufficiency, and no anaphylactic reaction, and is an ideal moisturizing and anti-oxidation skin moistening mask.

Apparatus and method for automatically inducing sleep deprivation in rodents with an electroencephalogram measurement and analysis system, an electromyogram measurement and analysis system, sleep deprivation stimulus, stimulus control, acquisition and real-time sleep stage analysis software, and cage with food and water supplies.

The invention provides a healthcare medicinal liquor for treating insomnia, which is prepared from the raw material of the following traditional Chinese herbal medicines: prepared rehmannia root, medlar, Ophiopogon japonicus, radix rehmanniae, Polygonum multiflorum, Dried Longan Pulp, Chinese angelica, oysters, longan pulp, Dioscorea opposita, rhizoma polygonati, salvia miltrorrhiza, Fructus Ligustri Lucidi, Bashfulgrass, licorice, White Peony Root, chinaroot greenbrier rhizome, Schisandra chinensis, Radix Aucklangiae, Notoginseng, Root or all-grass of Cairo Morningglory, root of carles indigo, rhizoma anemarrhenae, dried orange peel and Villous Amomum Fruit. The healthcare medicinal liquor has the outstanding advantages of no poisonous side effects, short curing course, and good treatment effects on the insomnia symptoms such as insufficient sleep, difficulty in falling asleep, failing to fall heavy sleep, waking early and failing to fall asleep again after waking, often being awakened from nightmare, nightmare feeling all night and feeling not recovered after sleeping, and has a good treatment effect on various uncomfortable symptoms and spiritual expression accompanying insomnia.

The invention discloses medicinal liquor for effectively treating insomnia, and the medicinal liquor is prepared through repeated verification of clinical tests in accordance to the theory of traditional Chinese medicine. The medicinal liquor is prepared from membrane of chicken gizzard, oriental waterplantain rhizome, tuckahoe, cassia twig, morinda officinalis, eucommia bark, Chinese thorowax, bitter orange, tuber fleeceflower stem, liquorice, baikal skullcap root, heterophylly falsestarwort root, longan pulp, thinleaf milkwort root bark, dens draconis, oyster, grass-leaved sweetflag, anemarrhena, dragon bone, tuckahoewithpine, spina date seed, ligusticum wallichii, Chinese angelica, yam, tulip, flower of silktree and platycladi seed. The medicinal liquor has the advantages of no toxic or side effect and short curative period, and has excellent treatment effects to main symptoms of insomnia, such as lack of sleep, difficulty in falling sleep, not sound sleep, early awakening, waking and not getting back to sleep, frequent awakening from nightmare, nightmare feeling all night, not renewed energy after sleep and the like, and also has excellent treatment effects to various uncomfortable symptoms and spiritual manifestation accompanying the insomnia.

A method for treating a person having sleep deprivation includes actively inducing unconsciousness in a person by administering an anesthetic agent to the person; determining an indication of a stage of sleep of the unconscious person by monitoring brainwaves of the person; and maintaining, for a predetermined period of time, the person in a state of sleep indicated to be deep sleep by adjusting the amount of the anesthetic agent being administered to the person. Preferably, the anesthetic agent is administered for about seven hours at different rates, and no surgical or other medical operation is performed. The anesthetic agent preferably is administered for the sole purpose of treating sleep deprivation.

The invention provides a sleep deprivation model system with simulation narrow and small spaces for pilots. The sleep deprivation model system comprises the closed spaces and a tested screening system. The tested screening system is arranged in the closed spaces and comprises a cognitive function assessment subsystem, a sleep quality assessment subsystem, an emotion assessment subsystem, a social function assessment subsystem and a sleep detection device; the cognitive function assessment subsystem is used for assessing cognitive behavior and cognitive functions of testees; the sleep quality assessment subsystem is used for assessing sleep behavior of the testees; the emotion assessment subsystem is used for assessing emotion indexes of the testees; the social function assessment subsystem is used for assessing social parameters of the testees; the sleep detection device is used for detecting sleep parameters of the testees. According to the technical scheme, the sleep deprivation model system has the advantage of accurate detection data.

The invention belongs to the technical field of devices for rat and mouse experiment study, particularly relates to a rat and mouse quick eyeball movement sleep deprivation water tank and mainly solves the problem that an existing sleep deprivation method is low in reliability of an experiment method and needs experiment personnel for realtime observation. The technical scheme includes that the rat and mouse quick eyeball movement sleep deprivation water tank comprises a water tank body, a partition is arranged on the middle-lower portion of the water tank body, a detachable bottom cover is arranged at the bottom of the water tank, multiple through holes are formed in each of the front side wall and the rear side wall of the detachable bottom cover, multiple uprights are movably arranged on the partition, a magnet is arranged at the bottom of each upright, multiple magnetic nails are arranged on the other side of the bottom of the partition and connected with the magnets at the bottoms of the uprights in a matched manner, a boss is arranged on the inner wall of the middle-upper portion of the water tank body, an isolating net is arranged on the boss movably, a cage cover is arranged at the top of the water tank body, a V-shaped groove is formed in one side of the cage cover, and a triangular partition is arranged in the V-shaped groove and divides the V-shaped groove into a food feeding area and a water feeding area.

The invention relates to a traditional Chinese medicinal composition for treating insomnia, and a preparation method thereof, and belongs to the field of traditional Chinese medicines. The traditional Chinese medicinal composition comprises 8-13g of Bupleurum chinense DC., 4-8g of Rhizoma arisaematis, 5-10g of American ginseng, 6-10g of Juncus effusus, 10-15g of pearl shells, 5-10g of Cortex Albiziae, 10-15g of Chinese yam, 5-7g of licorice root, 10-15g of Poria cocos, 10-15g of Semen Nelumbinis, 10-15g of immature bitter orange, 10-15g of Radix Polygalae, 10-15g of unprocessed keel, 5-10g of spine date seeds, 5-10g of Folium Phyllostachys, 10-15g of lily, 5-10g of chrysanthemum flower, 10-15g of Radix Puerariae, 5-10g of Radix Curcumae Aromaticae, 10-15g of Chinese magnoliavine, 10-15g of Dens Draconis, 8-12g of Chinese Eaglewood, 10-15g of peach seeds, 4-8g of oysters and 5-10g of Fructus Citri Sarcodactylis. A traditional Chinese medicinal capsule for treating insomnia, prepared from various Chinese herbal medicines, has the advantages of no toxic or side effects, easily available raw materials, and short cure course, has good treatment effects on sleep insufficiency, difficulty falling asleep, early awakening, sleeplessness after waking, frequent waking from a nightmare, nightmare suffering all night, and no energy recovery after sleep, and also has a good treatment effect on many discomfort symptoms and spirits associated with insomnia.

This invention relates to methods of use for AMPA receptor potentiator compounds and pharmaceutical compositions in the prevention and treatment of cognitive impairment as a result of acute or chronic sleep deprivation, including enhancement of receptor functioning at synapses in brain networks responsible for higher order behaviors. A still further aspect of the present invention is the use of an active agent as described above for the preparation of a medicament for the treatment of a disorder as described above.

The invention relates to food for resisting sleep deprivation stress damage. The formula comprises the following raw materials in percentage by mass: 53 to 63 percent of seed of spine date, 12 to 22 percent of fruit of roxburgh rose, 13 to 23 percent of ginsenoside and 2 to 12 percent of liquiritin. The food contains an extender, and the extender contains taurine and medlar, wherein the mass rateof the taurine to the medlar is 10:1. The formula of mixing four types of ingredients is applied to the sleep resistance. The ingredients mixed according to the formula can greatly reduce the damage to physical functions under the condition of sleep deprivation and has a certain application prospect in improving physical conditions of the persons(such as students, white collars and servicemen) ina continuous operating process.

A transgenic fly whose genome is modified to express enhanced levels of glutamate-cysteine ligase (GCL) gene is provided. The fly displays phenotypes associated with Alzheimer's disease (AD). Further, a method for diagnosing AD is provided, which includes assessing enzymatic activities in mitochondrial enzymes. Glutathione pathway are investigated by creating Alzheimer's model Drosophila with over-expression of the GCLc gene, inducing redox stress through sleep deprivation, and analyzing mitochondrial electron transport chain (ETC) using colorimetric enzymatic assays. For prevention of AD, it is proposed that the epigenetic approaches be used to increase glutathione levels in vivo before the onset of AD. For treatment of AD, it is proposed that the glutathione levels be increased by GCLc modulation.

The invention relates to a sleep deprivation device for rats/mice, which comprises a working platform, wherein the working platform is provided with standard feeding cages supported by food and waterand a guide rail, the plurality of standard feeding cages are arranged at two sides of the guide rail, at least one sleep deprivation rod walks on the guide rail, one side of each standard feeding cage, close to the guide rail, is provided with an elongated groove, and the sleep deprivation rod is inserted into the elongated groove; the sleep deprivation rod is driven by a motor, and the control end of the motor is connected with an industrial control device capable of setting motion parameters of the sleep deprivation rod; the guide rail is provided with a travel switch of the sleep deprivation rod, and the travel switch is connected with the industrial control device. The device is suitable for molding a plurality of sleep deprivation types, a plurality of groups can be carried out at the same time, and the cost is low; the environment of the mouse feeding cage is simulated by the deprivation cages, the generated stress response is small, and the interference on experimental data issmall; the rod deprivation mode is milder, the mice do not need to be in an exercise state all the time, the sleep deprivation method is mild but the deprivation effect is good, and the sleep deprivation mode more accords with a human sleep deprivation mode.