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Multi-platform water environment sleep deprivation water tank and system for animals

A technology of sleep deprivation and small animals, which is applied in the field of medical experiments, can solve problems such as hindering experimental design, animals cannot be free, and affect experimental efficiency, and achieve the effects of easy feeding, high space utilization, and high experimental efficiency

Active Publication Date: 2017-04-26
XIYUAN HOSPITAL OF CHINA ACAD OF CHINESE MEDICAL SCI
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

But whether the 2 weeks before the experiment has caused a lot of interference to the experiment itself, such as body weight and other factors, this just hinders the specific experimental design
[0005] And currently commercially available such devices (such as figure 1 ) mostly followed the design of the multi-platform sleep deprivation method, but in the experimental process, first of all, the pre-mixing of about 2 weeks before the experiment could not be fully satisfied, so that the experiment had the interference of uncertain factors; secondly, the experiment used The water tank is huge (about 120×65×45㎝ or even larger), and it is not easy to operate, and the number of more than a dozen small platforms affects the experimental efficiency; the height of the small platform is higher (about 10-15㎝), and the water demand is larger. Due to the deep water, it is very easy to cause the drowning of animals; the material of the small platform is mostly plastic, and rodents will bite it when stimulated; during the experiment, the experimental animals cannot freely eat and drink , adding unfavorable factors to the experiment

Method used

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  • Multi-platform water environment sleep deprivation water tank and system for animals
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Examples

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Effect test

Embodiment 1

[0069] A sleep deprivation system for rats, consisting of a stainless steel frame, water tank, water inlet and outlet, and controls. There are 4 layers in the frame, and 2 water tanks are placed on each layer, a total of 8 water tanks, which can satisfy 40 rats with a body weight of 200g to conduct sleep deprivation experiments at the same time. The bottom surface of the water tank is 500×350mm, the upper opening is 545×395mm, and the height is 200mm. A circular platform with a diameter of 60mm is arranged at the inner bottom, the height of the platform is 50mm, and the diameter of the standpipe supporting the platform is 10mm. The platform and standpipe are made of stainless steel with a thickness of 3mm. The number of platforms is 6, the platform is 100mm away from the water tank wall, and the distance between platforms is 150mm. Water inlets are arranged on the side of each water tank and connected to water inlet pipes. The distance between the water inlets and the bottom...

Embodiment 2

[0074] A sleep deprivation system for rats, consisting of a stainless steel frame, water tank, water inlet and outlet, and controls. There are 5 layers in the frame, and 2 water tanks are placed on each layer, a total of 10 water tanks, which can satisfy 50 rats with a body weight of 150 grams for sleep deprivation experiments at the same time. The bottom surface of the water tank is 500×350mm, the upper opening is 545×395mm, and the height is 200mm. A circular platform with a diameter of 50mm is arranged at the inner bottom, the platform height is 55mm, and the diameter of the standpipe supporting the platform is 13mm. The platform and standpipe are made of stainless steel with a thickness of 5mm. The number of platforms is 6, the platform is 100mm away from the water tank wall, and the distance between small platforms is 150mm. Water inlets are arranged on the sides of each water tank and connected to the water inlet pipes. The distance between the water inlets and the bot...

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Abstract

The invention belongs to the technical field of medical experiments and provides a multi-platform water environment sleep deprivation water tank and system for animals. Platforms are arranged in the bottom of the sleep deprivation water tank. The sleep deprivation system includes a rack, the sleep deprivation water tank, a water inlet / outlet device and a control device controlling experiment time, sewage disposal and cleaning. By adopting the water tank and the system provided by the invention, influence due to elements such as biological instability and the like in a sleep deprivation experiment is avoided. The experiment result is good in stability and high in repeatability. The device is high in operability, high in space utilization rate and good in application effect.

Description

technical field [0001] The invention belongs to the technical field of medical experiments and relates to a sleep deprivation device. Background technique [0002] Sleep deprivation method is widely used in the basic research of Chinese and Western medicine. Sleep deprivation can not only cause changes in the organism's mood, memory, etc. [1] , and can also cause changes in the expression of hormones, neurotransmitters, genes and even some specific proteins [2] , so sleep deprivation is not only one of the important methods to study the function and mechanism of sleep [3] , but also a typical endogenous source of oxidative stress [3] , some scholars believe that it is a pathogenic factor consistent with social pressure [5] . Scholars of traditional Chinese medicine were the first to use the water environment platform sleep deprivation method to establish a model of heart deficiency syndrome, and it has been widely used [6-7] . [0003] The quality of sleep deprivation...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A01K1/03
CPCA01K1/031
Inventor 刘建勋陈进成林成仁任钧国王磊沙甘加宽
Owner XIYUAN HOSPITAL OF CHINA ACAD OF CHINESE MEDICAL SCI
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