33 results about "Early Awakening" patented technology

Methods of preventing early awakenings, and improving sleep efficiency in hours 7 and 8 of a period of sleep, by administration of low doses of doxepin (e.g., 1-6 mg).

The invention relates to the field of pharmaceutical preparations, in particular to a timing pulsed release micro-pill of a zolpidem salt, which is characterized in that the center of the micro-pill is a blank pill core, an external time-lag layer is coated by low-permeability acrylic resin containing quaternary ammonium salt radicals, and a medicament layer and an organic acid layer are arranged between the blank pill core and the time-lag layer, wherein the organic acid layer contains a mixture of two organic acids, and the mixture of the two organic acids is prepared by mixing one of succinic acid, glutaric acid and adipic acid, and one of citric acid, malic acid and tartaric acid. Combining with sleep characteristics of early awakening crowds, the prepared micro-pill has certain release time lag and releases quickly after a period of time lag so that a patient obtains effective blood concentration on the point of awakening so as to prolong the sleep time of the patient.

The invention discloses medicinal liquor for effectively treating insomnia, and the medicinal liquor is prepared through repeated verification of clinical tests in accordance to the theory of traditional Chinese medicine. The medicinal liquor is prepared from membrane of chicken gizzard, oriental waterplantain rhizome, tuckahoe, cassia twig, morinda officinalis, eucommia bark, Chinese thorowax, bitter orange, tuber fleeceflower stem, liquorice, baikal skullcap root, heterophylly falsestarwort root, longan pulp, thinleaf milkwort root bark, dens draconis, oyster, grass-leaved sweetflag, anemarrhena, dragon bone, tuckahoewithpine, spina date seed, ligusticum wallichii, Chinese angelica, yam, tulip, flower of silktree and platycladi seed. The medicinal liquor has the advantages of no toxic or side effect and short curative period, and has excellent treatment effects to main symptoms of insomnia, such as lack of sleep, difficulty in falling sleep, not sound sleep, early awakening, waking and not getting back to sleep, frequent awakening from nightmare, nightmare feeling all night, not renewed energy after sleep and the like, and also has excellent treatment effects to various uncomfortable symptoms and spiritual manifestation accompanying the insomnia.

The invention belongs to the field of slow/controlled-release preparations, and particularly relates to a novel zolpidem tartrate oral timed pulse controlled-release delivery system and a preparation process thereof. The pulse controlled-release delivery system and a composition thereof comprise (A) a submicron solid dispersed medicament, (B) a solubilizing system tablet-containing core, and (C) a pulse controlled-release part, wherein the controlled-release part consists of a hydrophilic isolation coating, a hydrophobic controlled-release coating and an enteric coating. By adopting novel micronization and solid dispersion submicron solubilizing technologies, the problem of bioavailability of medicaments in enteral absorption, particularly in small intestine mid-segment absorption is solved; the pulse controlled-release delivery system is dissolved rapidly in intestines and is efficiently transferred through a biological film, so that a pulse blood concentration peak can be formed, the bioavailability is increased, and the pulse release delay time is 2-3 hours. The zolpidem tartrate oral pulse controlled-release delivery system is mainly used for treating early awakening disease of middle aged and elderly people.

The invention relates to a traditional Chinese medicinal composition for treating insomnia, and a preparation method thereof, and belongs to the field of traditional Chinese medicines. The traditional Chinese medicinal composition comprises 8-13g of Bupleurum chinense DC., 4-8g of Rhizoma arisaematis, 5-10g of American ginseng, 6-10g of Juncus effusus, 10-15g of pearl shells, 5-10g of Cortex Albiziae, 10-15g of Chinese yam, 5-7g of licorice root, 10-15g of Poria cocos, 10-15g of Semen Nelumbinis, 10-15g of immature bitter orange, 10-15g of Radix Polygalae, 10-15g of unprocessed keel, 5-10g of spine date seeds, 5-10g of Folium Phyllostachys, 10-15g of lily, 5-10g of chrysanthemum flower, 10-15g of Radix Puerariae, 5-10g of Radix Curcumae Aromaticae, 10-15g of Chinese magnoliavine, 10-15g of Dens Draconis, 8-12g of Chinese Eaglewood, 10-15g of peach seeds, 4-8g of oysters and 5-10g of Fructus Citri Sarcodactylis. A traditional Chinese medicinal capsule for treating insomnia, prepared from various Chinese herbal medicines, has the advantages of no toxic or side effects, easily available raw materials, and short cure course, has good treatment effects on sleep insufficiency, difficulty falling asleep, early awakening, sleeplessness after waking, frequent waking from a nightmare, nightmare suffering all night, and no energy recovery after sleep, and also has a good treatment effect on many discomfort symptoms and spirits associated with insomnia.

The invention provides a traditional Chinese medicine capsule for treating anhypnia, which is prepared by the following raw materials of burdock, radix morindae officinalis and celery roots. The traditional Chinese medicine capsule provided by the invention has the prominent advantages of being free of toxic and side effects, short in course of treatment, and good in treatment effect on the main symptoms of the anhypnia, such as sleep insufficiency, difficulty in falling asleep, difficulty in sleeping soundly, early awakening, difficulty in falling asleep after waking, frequently awaking from nightmares, self-feeling having nightmares all night, and incapability of restoring vigor after sleeping, the raw materials are easy to obtain, and the traditional Chinese medicine capsule is good in treatment effect for a plurality of discomfortable symptoms and spiritual expression along with the anhypnia.

The invention provides a traditional Chinese medicinal preparation for treating dysthymia. The traditional Chinese medicinal preparation is prepared from the following traditional Chinese medicinal materials: fossil fragments, rose flowers, shiraia bambusicola, rhizoma nardostachyos, concha haliotidis, herba epimedii, peach kernels, rhizoma polygonati, radix salviae miltiorrhizae, antelope's horn, pinellia ternata, radix bupleuri, Chinese yam, saffron crocus, albizia flowers, polygala tenuifolia, lotus seeds, the fruits of Chinese wolfberry, rhizoma gastrodiae, the root of bidentate achyranthes, prepared rehmannia root, rhizoma anemarrhenae, cinnabar, oyster, mint and spina date seeds. The traditional Chinese medicinal preparation has good clinical effects for patients suffering from depressive disorder at various stages, and has good treatment effects at the medication initial stage, the symptoms including insomnia, early awakening, dreaming and agriothymia are alleviated, the pain of the patient is greatly reduced, and the traditional Chinese medicinal preparation has the outstanding effect of being free of toxic and side effects, can rapidly improve the disease symptoms of the patients, has the advantages of significant curative effects and small possibility of relapse, and is low in treatment cost.

The invention provides a Chinese medicinal oral liquid for smoothing heart and enhancing intelligence. The Chinese medicinal oral liquid is prepared from the following Chinese medicinal raw materials: nutgrass galingale rhizome, cortex eucommiae, rehmannia root, Chinese taxillus twig, large-leaved gentian, twotooth achyranthes root, south dodder seed, turmeric root-tuber, thinleaf milkwort root-bark, bamboo shavings, immature bitter orange, spina date seed, uncaria, dens draconis, bamboo juice, sappan wood, prepared common monkshood daughter root, magnet, common burreed rhizome, peppermint, Chinese ephedra, dragon bone and red date. The Chinese medicinal oral liquid has a good clinical effect on upset major depression patients at every stage, a good treatment effect can be achieved at an administration initial stage, symptoms such as degradation of learning memory, insomnia, early awakening, dreaming, anxiety and the like are relieved, and the pain of patients is relieved greatly; theoral liquid plays a good role for preventing dysphoria of people who are under high working pressure and concentrate intensively every day; and the oral liquid has the outstanding effect of no toxic or side effect, can be used for rapidly improving symptoms of patients, and has the advantages of difficulty in relapsing, low treatment cost, and the like.

The invention discloses a novel compound sleeping pill, including a quick release drug release layer and a sustained and controlled release drug release layer. The two layers respectively contain a same sleeping pill or different sleeping pills, and the double layer tablet shows 15 min of rapid dissolution and up to 4 hours of slow dissolution after 2 h. By taking the double layer tablet, the effects of fast sleeping and early awakening prevention of a patient can be achieved.

The invention provides herbal tea capable of soothing nerves and sleep. The herbal tea is characterized that drier components include, by mass ratio, 15-30 of pepper wort herbs, 8-25 of sowthistle tasselflower herbs, 8-25 of christina loosestrife herbs, 6-10 of mint and 10-30 of cane sugar. The herbal tea has good curative effects on curing symptoms of insomnia and dreamful sleep, early awakening, malaise, dysphoria, irritability and the like and has preventing and therapeutical effects of overfrequency enuresis nocturna and frequent urination.

The invention provides a Chinese medicinal oral liquid for preventing and treating depression. The Chinese medicinal oral liquid is prepared from the following Chinese medicinal raw materials: szechuan lovage rhizome, costus root, nutgrass galingale rhizome, cortex eucommiae, rehmannia root, Chinese taxillus twig, large-leaved gentian, twotooth achyranthes root, south dodder seed, turmeric root-tuber, thinleaf milkwort root-bark, bamboo shavings, immature bitter orange, spina date seed, uncaria, dens draconis, bamboo juice, peach kernel, sappan wood, prepared common monkshood daughter root, magnet, common burreed rhizome, peppermint, Chinese ephedra, dragon bone, large-head atractylodes rhizome and Chinese date. The Chinese medicinal oral liquid has a good clinical effect on upset major depression patients at every stage, a good treatment effect can be achieved at an administration initial stage, symptoms such as degradation of learning memory, insomnia, early awakening, dreaming, anxiety and the like are relieved, and the pain of patients is relieved greatly; the oral liquid plays a good role for preventing dysphoria of people who are under high working pressure and concentrate intensively every day; and the oral liquid has the outstanding effect of no toxic or side effect, can be used for rapidly improving symptoms of patients, and has the advantages of difficulty in relapsing, low treatment cost, and the like.

The invention discloses an orally-taking medicine for treating insomnia and a production method thereof. The orally-taking medicine for treating insomnia is prepared from, by weight, 5-100 parts of lavandula, 10-50 parts of adiantum, 30-50 parts of anchusa azurea, 30-50 parts of licorice roots, 30-50 parts of chicory roots, 30-50 parts of celery roots, 30-50 parts of calendula, 30-50 parts of hollyhock seeds, 30-50 parts of fennel velamen, 30-50 parts of fennel fruits, 30-50 parts of roses, 30-50 parts of medicine dates, 30-50 parts of cordia dichotoma fruits, 30-50 parts of sweet basil herbs and 30-50 parts of rhizoma nardostachyos. The orally-taking medicine for treating insomnia has the effects of maturing and removing abnormal phlegmatic temperament, dredging stasis, calming the nerves, improving sleeping, resisting inflammation and the like, and is suitable for insomnia, dreaminess and the like. The orally-taking medicine has the advantages that the curing course is short, the good treatment effect is achieved on main insomnia symptoms that sleeping is insufficient, sleep falling is difficult, heavy sleeping cannot be achieved, early awakening occurs, sleep re-falling cannot be achieved after awakening, frequent awakening is caused by bad dreams, a person feels having bad dreams all night, and vigor is not recovered after sleeping, and the good treatment effect is also achieved on multiple discomfort symptoms and spirit expression accompanied by insomnia.

The invention relates to a traditional Chinese medicine formula for treating insomnia. The proportion of the medicine components is: 10-14 parts of lily, 8-12 parts of angelica, 6-10 parts of Fushen, 6-8 parts of licorice, and 7-12 parts of jujube 10-15 parts of tangerine peel, 6-10 parts of amber, 4-8 parts of bamboo, 8-10 parts of salvia miltiorrhiza, 8-12 parts of peony bark. The medicine of the present invention has the effects of nourishing yin and replenishing qi, benefiting the mind and calming the mind, calming the mind and calming the mind, and has good treatment for symptoms such as difficulty in falling asleep, too short sleep depth or frequency, early awakening, insufficient sleep time or poor quality caused by insomnia Effect.

A health-care pillow for preventing and treating somatic mental illness of heart-liver-phlegm depression, characterized in that the raw materials contained in the pillow core are composed of 85-93 grams of Rhizoma Cyperi, 77-85 grams of Polygala, 80-96 grams of Schisandra, and 82 grams of Scallion ‑88g, Citrus aurantium 85‑96g, Rhizoma Cyperi 83‑89g, Ginseng 89‑96g, Atractylodes macrocephala 88‑92g, Angelica 87‑95g, Radix Paeoniae Alba 89‑98g, Keel 90‑97g, Araceae 85‑95 grams, 87‑96 grams of tangerine peel, 99‑105 grams of poria cocos, this health pillow achieves the purpose of relieving somatic mental illness of heart, liver and phlegm depression by soothing the liver and relieving depression, dispelling wind and phlegm, calming the mind and calming the nerves, and relieves Insomnia, early awakening, loss of memory and concentration, no symptoms of appetite and gastrointestinal dysfunction, so that patients can get a good sleep at night to ensure the quality of sleep, so as to soothe the liver and nourish the heart, resolve phlegm and relieve depression, and effectively prevent and treat heart and liver phlegm depression The role of type somatic psychosis.