104 results about "Hyperforin" patented technology

The invention discloses an anti-insomnia composition, an application of the composition, a multi-phase pulse immediate-release preparation prepared by use of the composition and a preparation method of the preparation. The anti-insomnia composition consists of a component A and a component B, wherein the component A is one or more of melatonin, melatonin analogue and corresponding salt, melatonin receptor stimulant, 5-hydroxytryptamine 2C, receptor antagonist and 5-HTP (5-hydroxytryptophan); the component B is one or more of petroselinum neapolitanum extract, melissa extract, tuber fleeceflower stem extract, chamomile extract, passion flower extract, radix paeoniae alba extract, manyprickle acanthopanax extract, polygala tenuifolia extract, hyperforin perforatum extract, flos albiziae extract, lily extract and prunella vulgaris extract. The composition and the multi-phase pulse immediate-release preparation prepared by use of the composition have the characteristic of better anti-insomnia effect than a common melatonin preparation, and can effectively solve and improve the problem of difficult sleep of human or mammals while effectively solving and improving the insomnia problems such as light sleep or dreaminess or early awakening or difficult sleep after wakeup of human or mammals.

The invention discloses a traditional Chinese medicine air disinfectant which is prepared by the following traditional Chinese medicinal materials by weight: 10-30g folium artemisiae argyi, 8-15g cordate houttuynia, 5-20g honeysuckle, 1-10g hyperforin perforatum, 2-10g radix sophorae flavescentis, 2-10g herba violae, 1-10g radix scutellariae, 3-15g fructus cnidii, 1-10g agastache rugosus, 1-10g herba eupatorii, 5-6g golden cypress, and 5-10g magnolia officinalis. The air disinfectant is a pure traditional Chinese medicine preparation, is non-irritant, non-corrosive, safe to use, and wide in application scope, and has a significant environment-friendly effect.

The invention relates to natural plant extracts, particularly relates to a mixture of natural plant extracts and a preparation method and application of the mixture and particularly discloses extracts of lemon eucalyptus, rosemary, liquorice, cinnamon and hyperforin perforatum and application of extracts in preparation of a disinfecting agent. Natural edible plant constituents serve as effective antibiotic constituents, other natural food additive constituents such as citric acid and sodium citrate are added to prepare the pure natural plant type disinfecting agent which is safe and nontoxic, and the disinfecting agent has the good preservation effect.

St. John's Wort products which have enhanced bioactivity in a serotonin re-uptake assay and enhanced stability and bioavailability are formulated and manufactured from hyperforin-enriched Hypericum fractions made by supercritical and near critical fluids with and without polar cosolvents. These fluids are used to fractionate the biomass materials in several sequential steps. In each step, the biomass is subjected to a multiplicity of supercritical or near critical fluid extraction steps, with different solvation conditions used for each fraction. Thus, fractionation of the biomass is effected and the St. John's Wort products are manufactured. In addition to excellent overall yield, the bioactivity and stability of the St. John's Wort products manufactured from Hypericum perforatum biomass with supercritical and near critical fluids with and without polar cosolvents are significantly higher than that obtained by conventional organic phase extraction. The advanced formulation of the hyperforin-enriched Hypericum fractions includes antioxidants as oxygen scavengers to improve stability and emulsifiers such as lecithin to improve bioavailability.

The invention discloses a sanitary towel core plate with plant bacteriostatic and odor removing functions. The sanitary towel core plate with plant bacteriostatic and odor removing functions is prepared through the following steps of: compounding a geranium wilfordii extracting solution, a hyperforin perforatum extracting solution, a mentha haplocalyx extracting solution, a mother chrysanthemum extracting solution, a radix angelicae extracting solution, a herba asari cum radice extracting solution, a radix asparagi extracting solution, a dandelion extracting solution, a Chinese honeylocust fruit extracting solution and deionized water into a stock solution with bacteriostatic and odor removing functions; then spraying the stock solution uniformly on non-woven cloth on a non-woven cloth production line by a spraying method; then rewinding, slitting and packaging the non-woven cloth, wherein the obtained finished product is the sanitary towel core plate with plant bacteriostatic and odor removing functions. The sanitary towel core plate produced by the disclosed method has the functions of restraining bacterial breeding and relieving odor, meanwhile is safety to human bodies, and has no irritation.

Described are salts of hyperforin and adhyperforin of formula Iwherein m is an integer from 1 to 3, p is equal to m and gives the total number of positive charges of the residue [B],[A-] is an anion of formula II with n=0 or 1and [B]p+ is an ion of an alkali metal or an ammonium ion of a salt-forming nitrogen base of formula IIIwherein R1 through R4 have a variety of meanings including hydrogen, alkyl, cycloalkyl and similar groups which in turn may be substituted with one or more substituents. The salts serve inter alia for enriching or purifying hyperforin and adhyperforin from St. John's Wort extracts. Pharmaceutical preparations containing the salts are used for treating Alzheimer's Disease.

The invention provides a type-B ultrasonic traditional Chinese medicinal gastroenterography assistant and a method for preparing the same. The traditional Chinese medicinal gastroenterography assistant comprises egg shells, asteroid, clam shells, elaeagnus pungens, hairyvein agrimony, licorice, calcined dragon bone, hyperforin, purple lythrum herbs, kadsura longipedunculata, rhubarb, roots of yellow Himalayan raspberry, cornu cervi degelatinatum, red umbilicaria, hop, amomum aromaticum, wampee, rhizoma nardostachyos, areca peels, pugionium and curcuma zedoaria. The type-B ultrasonic traditional Chinese medicinal gastroenterography assistant and the method have the advantages that the type-B ultrasonic traditional Chinese medicinal gastroenterography assistant is safe in use, free of allergic reaction, short in examination time, high in developing rate, convenient to use and low in cost and is painless, noninvasive and non-toxic, a novel technology and a novel method are provided for early and accurate diagnosis of diseases, a powerful basis for clinical diagnosis is provided, the type-B ultrasonic traditional Chinese medicinal gastroenterography assistant is perfect and novel, and a process for manufacturing the type-B ultrasonic traditional Chinese medicinal gastroenterography assistant is simple and practical.

The invention discloses an air disinfectant. The air disinfectant comprises the following raw materials by mass percent: 30-45% of ethanol, 3-7% of lauric acid, 10-20% of acetic acid, 2-5% of sodium benzoate, 5-10% of wormwood, 3-7% of aloes, 5-15% of isatis root, 5-10% of hyperforin perforatum, 10-20% of wild chrysanthemum and the balance of water. The air disinfectant ingeniously combines traditional Chinese medicines with chemical disinfectants, has obvious disinfection effects, low toxicity and little impact on the air environment, does not have pungent smell, does not harm human health and is environment-friendly.

The invention belongs to the field of traditional Chinese medicine, discloses a traditional Chinese medicine gel capable of promoting a skin wound to heal and is characterized by comprising a high molecular material, a penetration enhancer, a surfactant, a pH modifier, a preservative, water and traditional Chinese medicine clear paste prepared through raw materials of hyperforin perforatum, herb of denseleaf crazyweed, radix zanthoxyli, herb of thymeleaf speed welt, euonymus fortunei, hibiscus mutabilis and bletilla striata. According to the Chinese medicine gel capable of promoting the skin wound to heal, all medicine interacts collaboratively, stasis can be eliminated to subdue swelling, heat and toxic materials can be cleaned away, and effects of antisepsis and anti-inflammation as well as removing necrotic tissue and promoting granulation are realized. The effects of rapidly relieving patient's pain, rapidly healing the wound, removing blood stasis for promoting tissue regeneration and activating blood and dissipating stasis are realized; besides, the traditional Chinese medicine gel is uniform and fine and easy to coat after folding, the residence time is long, skin won't be tightened, the gel is stable to release, the stability is good, no toxic or side effect exists, the obedience of a patient for receiving treatment is improved greatly, and the life quality of the patient is improved.

Hypericum perforatum L. Oleoresin, procedure for obtaining it and uses of it. A Hypericum perforatum L Oleoresin is describes that is stable over time on its Hyperforin and Hypericine content without adding preservatives; a procedure for obtaining the Oleoresin by extraction with low-polarity solvents, followed by purification; also its use as a regulator of the components of the extracellular matrix is described and its use for the manufacture of hydrosoluble gels containing Hypericum perforatum L Oleoresin.

The invention relates to a traditional Chinese medicine for treating depression. The traditional Chinese medicine is prepared from acanthopanax brachypus, tuber fleeceflower stem, buckbean, hyperforin perforatum, red rhodobryum, fiveleaf akebia fruit, dried prickly pear sap, platycodon grandiflorum, turmeric, apocynum venetum, cicada slough, black bean peel and Chinese date. The traditional Chinese medicine can be used for clinically treating depression.

The invention discloses a compound traditional Chinese medicine for treating depression. The compound traditional Chinese medicine taking Chinese herbaceous peony, radix bupleurim, turmeric, hyperforin perforatum, purple perilla, rhizoma anemarrhenae and long pepper as raw materials is extracted and separated by 0-75% ethanol and prepared as medically acceptable oral preparations such as troches, capsules (soft or hard capsules) and particles. The drafted major functions of the compound traditional Chinese medicine are soothing liver-qi stagnation and dispersing blood stasis and dredging collateral, and the compound traditional Chinese medicine is used for treating mild-to-moderate depression. The pharmacological researches show that the pharmaceutical composition can remarkably enhance open field activity of chronic stress depression mode mice and increase the consumption of sweet water; antagonizes akinesia and hypothermia of chronic stress depression mode mice induced by reserpine, so that the number of autonomic activities of despair animal mode induced by tail suspension and forced swimming and tail suspension and swimming immobility time are increased. The compound traditional Chinese medicine disclosed by the invention with the functions of soothing liver-qi stagnation is an effective special medicine for treating depression.

The invention discloses a traditional Chinese medicine disinfectant and a preparation method of the traditional Chinese medicine disinfectant, and belongs to the field of traditional Chinese medicines. The disinfectant is mainly prepared from the following raw materials by weight: 3-15 parts of radix bupleuri, 2-12 parts of mint, 3-10 parts of cortex phellodendri, 2-9 parts of hyperforin perforatum, 4-8 parts of areca-nut, 1-10 parts of radix ophiopogonis, 4-9 parts of herba houttuyniae, 3-11 parts of rhizoma coptidis, 4-11 parts of honeysuckle, 5-10 parts of liquorice, 2-8 parts of euphorbia kansui, 3-9 parts of cortex albiziae, 2-6 parts of radix ophiopogonis, 3-7 parts of fructus cnidii, 2-8 parts of Japanese cayratia herb, 5-8 parts of folium artemisiae argyi, and 300-600 parts of ethanol solution. The selected medicines of the traditional Chinese medicine disinfectant are compatible, the traditional Chinese medicine disinfectant has the advantages of high bactericidal ability and high stability, and in addition, the preparation method of the disinfectant is simple, the operation is convenient, and the traditional Chinese medicine disinfectant and the preparation method of the traditional Chinese medicine disinfectant are higher in application value.

The invention belongs to the field of Chinese herbal medicines, and particularly relates to a production method of a hyperforin perforatum extract. The method is characterized by comprising the following steps: pretreatment of raw materials, extraction, leaching, concentration and the like. The hypericin content in an extract product is improved on the basis of ensuring active ingredients of various components of the product.

The invention relates to the technical field of natural medicine chemicals and in particular relates to application of hyperforin to preparation of a medicine for promoting browning of white fat and improving the activity of brown fat. On the basis of action mechanisms of promoting browning of white fat and improving the activity of brown fat, the hyperforin has an effect of increasing energy consumption of a body to lose weight; in addition, the hyperforin has the effects of reducing blood sugar and blood grease levels, improving sugar resistance, improving insulin sensitivity and maintainingglycometabolism steadiness, and thus can be used as a medicine for relieving diabetes symptoms; in addition, the hyperforin can be also used for relieving or treating non-alcoholic fatty liver diseases. Therefore, the hyperforin, an extract with the hyperforin, or a preparation of the hyperforin has wide clinical application prospects in preventing or treating metabolic syndromes such as obesityand diabetes.

The invention discloses a cosmetic composition and emulsion with a breast enlarging effect. The cosmetic composition consists of the following components in parts by weight: 0.1 to 10 parts of lupulusextract, 0.1 to 10 parts of hyperforin perforatum extract, 0.1 to 10 parts of Salvia officinalis extract and 0.1 to 10 parts of saponaria leaf / root extract. The breast enlarging emulsion prepared inthe invention has the breast health effects of improving the breast skin condition, promoting the breast compactness and increasing the chest circumference, and does not contain a preservative, so that the emulsion is safe and convenient to use.

The invention discloses a preparation method of a chicken feed additive containing chitosan. The chicken feed additive comprises the following raw materials: 15-30 parts of chitosan, 10-30 parts of isomaltose hypgather, 3-6 parts of a hyperforin perforatum extract, 8-10 parts of a dandelion extract and 8-10 parts of a licorice extract. The preparation method comprises the following steps: extracting the dandelion extract, the licorice extract and the hyperforin perforatum extract respectively, and then uniformly mixing the dandelion extract, the licorice extract and the hyperforin perforatum extract with chitosan and isomaltose hypgather so as to obtain the chicken feed additive containing chitosan. The chicken feed additive can be effectively used for improving the egg laying rate, and strengthening the immunity of chicken without adding antibiotics, and is beneficial to laying environment-friendly eggs.

The invention provides a Chinese medicine composition for treating depression. The Chinese medicine composition is prepared from scorpion, tuber fleeceflower stem, hyperforin perforatum, fiveleaf akebia fruit, rhizoma acori graminei, polygala tenuifolia, rhizoma anemarrhenae, radix curcumae, periostracum cicada, jujube and liquorice. The composition can be used for treating depression in clinic.

The invention discloses a method for preparing a hypericum perforatum extract. By the preparation method, a stable composition of the hypericum perforatum extract can be prepared, particularly a hypericin and hyperforin-containing composition. In addition, the invention also discloses a stable composition of the hypericum perforatum extract and use thereof for preparation of medicaments.

The invention relates to the field of animal and plant and plant application research (combination), particularly to a preparation process and method of serum for skin repairing. The serum comprises the following raw materials: a propolis extract, a honey extract, a royal jelly extract, beta-glucan, acetyl Hexapeptide-8, L-Carnosine, oligopeptide-32, oligopeptide-1, peony flower / leaf / root extract,aloe vera extract, carbomer, xanthan gum, a mung bean extract, a centellae herba extract, a plantain herb extract, a hyperforin perforatum extract, rosemary leaf water, imidazolidinyl urea, xylitol,capryloyl hydroxamic acid, glycerol, sodium hyaluronate, butanediol, and water. According to the invention, animal extracts are combined with plant extracts to prepare the skin care product having theeffects of repairing skin injuries, supplementing skin nutrition, improving skin blood circulation, updating skin cell regeneration, improving skin elasticity and softness, improving skin quality, removing skin yellow melanin and enabling skin to be white and bright.

The oral medicine for treating depression, named Jinyukang, is prepared with extractive of the effective part of Hypericum perforatum. It features that total content of hypericin and pseudohypericin of 0.15-48%, rutin content of 2.3-4%, general flavone content of 50-90% and hyperforin content of 2-46%. The oral preparation includes tablet, capsule, medicine powder and oral liquid. The extractive is extracted directly from Hypericum perforatum or refining coarse extractive of Hypericum perforatum.

The invention discloses a natural skincare product for moisturizing, repairing and improving skin and delaying oriental skin senescence. The natural skincare product comprises the following raw materials in percentage by mass: 3% of cetyl stearate-based olive oil grease, 2% of sorbitol olive oil grease, 3% of wheat-germ oil, 5% of Australia harizonaelnut oil, 3% of shea butter, 2% of crambe seed oil, 1% of vitamin A, 5% of glycerin, 1% of provitamin B5, 1% of an alchemilla extracting solution, 1% of an arnica extracting solution, 1% of a witch hazel extracting solution, 1% of a hedera helix extracting solution, 1% of a Chinese buckeye extract, 1% of a hyperforin perforatum extract, 1% of red grapes extract, 1% of a peony root extract and 67% of water. The natural skincare product is completely prepared from pure natural raw materials, and is appropriate in ratio; a thickener and the like harmful to a human body are not added; the burden to the skin caused by the additive is reduced to the maximal extent; and the natural skincare product has the advantages of moisturizing, repairing the skin, improving the skin, and delaying senescence.

The invention discloses antibacterial gynecological gel. The antibacterial gynecological gel is prepared from the following components in parts by weight: 1 to 3 parts of a solubilizer, 2 to 3 parts of a bactericide, 80 to 92 parts of purified water, 0.8 to 1.5 parts of ginger root extract, 0.8 to 1.5 parts of Chinese wampee tree extract, 0.8 to 1.5 parts of hyperforin perforatum extract, 0.8 to 1.5 parts of artemisia capillaris extract, 0.8 to 1.5 parts of radix stemonae sessilifoliae extract, 0.8 to 1.5 parts of radix sophorae flavescentis extract, 0.8 to 1.5 parts of fructus cnidii extract and 0.8 to 1.5 parts of radix scutellariae extract, wherein the bactericide is one or a composition of two or more of a cationic bactericide, a silver ion bactericide or an ozone bactericide. According to the antibacterial gynecological gel disclosed by the invention, multiple bactericides are adopted to synergistically play an antibacterial role, so that the gel has a good antibacterial effect and also has a killing effect on staphylococcus aureus, candida albicans, escherichia coli and the like; and the antibacterial efficiency of the antibacterial gynecological gel can reach 96 percent to the maximum extent, and meanwhile, the antibacterial gynecological gel has good viscosity, humidity and comfort and has a good effect of keeping vagina health.

The invention discloses a extractive method of hyperforin phenolic acid and preparation method of hyperforin phenol acid injection. The hyperforin phenolic acid is consisted of total phenolic acid of more than 95 % and total hypericin of 1.2 %. The extraction method of the hyperforin phenolic acid is characterizing by: reflux extracting medicinal materials 3 times with 75 % ethanol, degreasing with ether, extracting with ethyl acetate, eluting D101 resin, which extraction is absorbed on, with ethanol of 40 % and 80 %, concentrating residual liquid and eluent of 40 %, separating by column chromatogram of polyamide, extracting by ethyl acetate, drying, getting phenolic acid extract and mixing with dry matter of 80 % ethanol eluent to prepare hyperforin phenolic acid (intermediate). The injection is prepared of intermediate, medicinal assistant material and water for injection, and can produce to small injection, transfusion agent and freezing-dried powder injection. The injection has high bioavailability, high concentration of blood and medicine, quick effect, and exact curative effect for curing depression, virus A and B hepatitis.

The invention discloses a preparation method of a medicament for resisting dampingoff. The preparation method comprises the following steps of A, preparing materials: 38% bacterial wilt pesticide, 72.2% hymexazol, 75% thiodiazole-copper wettable powder, baicalin, matrine, indirubin, Chinese pulsatilla root and hyperforin perforatum; B, lixiviating an extracting solution of Chinese pulsatilla root and hyperforin perforatum with alcohol; and C, compounding 38% bacterial wilt pesticide, 72.2% hymexazol, 75% thiodiazole-copper wettable powder, baicalin, matrine and indirubin with the extracting solution obtained in step B, uniformly stirring and then carrying out ultraviolet sterilization to prepare a disease-resistant medicament for chili seedling dampingoff. The preparation method disclosed by the invention is simple, a prepared product is simple in proportioning and convenient to use and good in effects on treatment of chili seedling damping-off. Experiment tests show that the liquid of 400-600 times of a mixture of the medicament has obvious inactivation functions on pythium, phytophthora, rhizoctonia and the like and has good sterilization effects.

The invention discloses a disinfectant for the laboratory department. The disinfectant is prepared from, by mass, 10-20 parts of hyperforin perforatum, 10-20 parts of radix scutellariae, 20-35 parts of cassia bark, 25-35 parts of fortune eupatorium herb, 10-15 parts of common cnidium fruits and 5-10 parts of coptidis rhizome. In another embodiment, the disinfectant is prepared from, by mass, 12-18 parts of hyperforin perforatum, 12-16 parts of radix scutellariae, 25-30 parts of cassia bark, 26-32 parts of fortune eupatorium herb, 11-14 parts of common cnidium fruits and 7-9 parts of coptidis rhizome. After being mixed according to the proportion, the compositions are all prepared from traditional Chinese medicine ingredients, and are innoxious and harmless to the human body after interaction, other chemical ingredients are not contained, accumulative damage to the human body caused after long-time use is reduced, the environment-friendly property of the disinfectant can be kept, and no negative effect is generated even though the disinfectant is used for a long time.

The invention discloses an application of Hyperforin ethyl ester with a structure I1 and / or Hyperforin-N, N dicyclohexyl ammonium with a structure I2 in preparing drugs capable of treating tumor. The pharmacological pharmacodynamics experiment proves that the Hyperforin ethyl ester and the Hyperforin-N, N dicyclohexyl ammonium of the invention have the action of specific proliferation inhibition, apoptosis induction, cell cycle influence and the like on human tumor cells cultured in vitro and provide new drug selection for clinic tumor therapy.

The invention discloses a biopesticide for controlling walnut black spot and a preparation method, belonging to the technical field of pesticides. Chinese herbal medicines, namely radix gentianae macrophyllae, cassia twig, radish, calendula officinalis, spanishneedles herb, hyperforin perforatum, thomson sreeper root or stem and kaleniczenk euphorbia herb, are subjected to grinding and ethanol extraction to obtain the biopesticide. According to field control trials, the control effect on walnut black spot is better than that of the control group; and particularly, the biopesticide is prepared from pure natural Chinese herbal medicines so as to avoid environmental pollution and residue.

The invention discloses an external traditional Chinese medicine preparation for treating trauma and infection. The preparation is characterized by being composed of the following traditional Chinese herbals in parts by weight: 10 to 15 parts of hyperforin perforatum, 5 to 10 parts of phellodendron, 15 to 20 parts of esliptae herba, 20 to 30 parts of myrtle leaf, and 10 to 15 parts of mangosteen. The preparation has the functions of diminishing inflammation, relieving pains, expelling pus, dispelling putridity, stopping bleeding, sterilizing, clearing heat, removing toxicity, and dissipating stasis; has a prominent curative effect on burns, scratches, stab wounds, and the like, and has the advantages of no side or toxic effect, user-friendliness, and low cost.

The invention relates to a Chinese herb extract capable of removing facial red blood, a skin cream and a preparation method thereof. Active ingredients of the Chinese herb extract comprise, by weight, 20-50 parts of astragalus membranaceus, 20-40 parts of hyperforin perforatum, 20-40 parts of ivies, 10-30 parts of angelica sinensis, 10-30 parts of witch hazel and 10-30 parts of lucid ganoderma. The Chinese herb extract has a remarkable effect on removing the facial red blood; the Chinese herb extract is applied into the skin cream so that the problem of the facial red blood can be effectively solved; and stimulation and the side effects of allergy, reliability and the like do not occur.