12 results about "Hyperforin" patented technology

The invention discloses herbal oil control essence. A component A comprises deionized water and sodium hyaluronate; the component B comprises methylpropanediol, a hyperforin perforatum flower / leaf / stem extract, cyclodextrin and a rehmannia chinensis root extract; the component C is prepared from water, butanediol, amur corktree bark extract, coptis root extract, radix sophorae flavescentis extract, rhus chinensis insect gall extract, cnidium monnieri fruit extract, zanthoxylum bungeanum fruit extract and camphor tree leaf extract; and the component D comprises 1, 2-hexanediol. The preparation method of the herbal oil-control essence comprises the following steps: S1, preparing raw materials; s2, preparing the component A; s3, preparing the component B; s4, preparing a component C; s5, a mixing process; and S6, adding a component D and carrying out post-treatment. The herbal components form a synergistic effect network and act on a skin grease secretion system in a targeted manner, grease secretion is balanced from the source by adjusting the biological activity of sebaceous gland cells, meanwhile, biological signal channels related to skin anti-inflammation, moisturizing and tightening are activated, and the multiple-effect-in-one skin care effect is achieved.

The invention discloses a refreshing oil-control composition as well as a preparation method and application thereof, and belongs to the field of daily cosmetic preparations. The refreshing and oil-control composition is prepared from the following components: a skin conditioning component, Lignum seu Fructus Liu Citri sodium oleate, sodium cocoyl aminopropionate, disodium lauroyl glutamate, lauramide propyl betaine and a solvent, the skin conditioning component consists of a hyperforin perforatum flower / leaf / stem extract, a capparis spinosa fruit extract and a sanguisorba officinalis root extract. The refreshing oil-control composition provided by the invention has excellent performance of inhibiting grease secretion of human sebaceous gland cells, and has an excellent deep oil-control effect on skin; according to the present invention, the stellaria mellea L sodium oleate, the cocamidopropyl sodium propionate, the disodium lauroyl glutamate and the lauramide propyl betaine are matched to use so as to provide effects of good foaming power and stable and lasting foam; the refreshing oil-control cleaning product provided by the invention can obviously reduce the grease content of skin, improve oily skin and realize an oil-control effect.

The application discloses application of an active ingredient hypericin in Hypericum perforatum in preparation of anti-migraine drugs, relates to the technical field of medicines, and identifies the active ingredient hypericin that can enter the brain from Hypericum perforatum extract, further combines BV2 cell in-vitro anti-inflammatory experiments, and analyzes blood rheology indexes of cerebral blood vessels and blood stasis changes after drug administration of rats, and confirms that the hypericin has good anti-migraine effect. The application provides definite experimental basis for the application of the active ingredient in anti-migraine drugs.

The invention belongs to the technical field of natural anti-corrosion materials, and provides a natural anti-corrosion composition containing cinnamon bark extract and a preparation method and application of the natural anti-corrosion composition. The natural preservative composition provided by the invention comprises a cinnamon bark extract and a synergistic compound, the synergistic compound comprises a mangnolia officinalis bark extract, a perilla leaf extract, a rhizoma atractylodis root extract, a folium artemisiae argyi extract, a wrinkled gianthyssop herb extract, a radix ophiopogonis root extract, a pomegranate seed extract, a pomelo extract, a thyme leaf extract, a calendula extract, a hyperforin perforatum extract, a melaleuca alternifolia leaf extract, a ginger root extract and an eucalyptus globulus leaf extract; the mass content of cinnamyl aldehyde in the cinnamon bark extract is less than or equal to 20wt%, and the antibacterial composition has the advantages of broad-spectrum bacteriostasis, high stability, difficulty in discoloration and precipitation, acid and alkali resistance, high temperature resistance, safety and small irritation. The antibacterial composition is prepared from at least one of a ginseng root extract, a rosemary leaf extract, a papaya fruit extract, a chamomile flower extract, a soybean seed extract and a wheat bran extract, and the mass content of cinnamyl aldehyde in the cinnamon bark extract is less than or equal to 20wt%.

The invention discloses a traditional Chinese medicine compound composition for preventing and treating liver injury as well as a preparation method and application thereof. The compound composition comprises verbena, alfalfa, Chinese ladiestresses root, hairyvein agrimony, fingered citron, malt and hyperforin perforatum. The traditional Chinese medicine composition is simple in composition and reasonable in proportion, and animal experiments prove that the traditional Chinese medicine composition can improve the liver function, relieve liver inflammation injury, inhibit liver cell necrosis and fatty degeneration, inhibit oxidative stress and resist lipid peroxidation injury and has good prevention and treatment effects on liver injury, cholestatic liver diseases and the like caused by drugs. And the traditional Chinese medicine composition can obviously improve the symptoms such as weakness, nausea, skin and sclera yellow staining, yellow urine, itching, stomachache, hypochondrium lumps, body emaciation and the like in the liver injury period. The medicine is simple in preparation method, convenient to take, low in price, small in side effect and good in curative effect, and provides a good choice for vast patients with hepatopathy.

The invention belongs to the field of daily chemicals, and discloses an oil-control soothing composition which comprises the following components in parts by weight: 0.5-5 parts of a yeast / zinc fermentation product; 0.5-5 parts by weight of a lactobacillus fermentation lysate; 0.5 to 5 parts by weight of dipeptide-15; 0.1-10 parts by weight of a flower / leaf / stem extract of hyperforin perforatum; and 0.5-5 parts by weight of an olive leaf extract. The composition adopts a yeast / zinc fermentation product, a lactobacillus fermentation lysate, dipeptide-15, a hyperforin perforatum flower / leaf / stem extract and an olive leaf extract to control oil from multiple angles, a good oil control effect is achieved, and meanwhile, the formula of the composition also has a relatively good soothing performance. Meanwhile, the invention further discloses application of the composition and cosmetics.

The invention belongs to the technical field of photosensitive materials, and particularly relates to a plant source exosome, a preparation method thereof and application of the plant source exosome as a photosensitizer. The plant source exosome is extracted according to the following method: step 1, extracting hyperforin perforatum by using a PBS (Phosphate Buffer Solution); 2, separating the extracting solution, and concentrating through an ultrafiltration concentration tube; and step 3, adding a PBS solution, and uniformly mixing to obtain the pure exosome. The exosome disclosed by the invention has photosensitivity, can be used as a photosensitizer to be applied to photodynamic therapy and photodynamic diagnosis, and has a very good application prospect.

The invention relates to the technical field of traditional Chinese medicine composition preparation and application, and particularly discloses a traditional Chinese medicine composition for treating ulcerative colitis and a preparation method and application thereof. The traditional Chinese medicine composition comprises the following traditional Chinese medicine raw materials: hyperforin perforatum, myristica fragrans, codonopsis pilosula nnannf, herba patriniae, semen cuscutae, vinegar schisandra chinensis, roasted rhizoma atractylodis macrocephalae, carbonized sanguisorba root, fructus evodiae, radix curcumae, radix paeoniae alba, rhizoma zingiberis, smoked plum, radix aucklandiae, coptis chinensis and liquorice. The traditional Chinese medicine raw material composition and dosage compatibility of the traditional Chinese medicine composition conform to the traditional Chinese medicine differentiation theory, the levels of IL-1beta, IL-6 and TNF-alpha in DAI and serum of chronic ulcerative colitis rats can be effectively reduced, Claudin-1, ZO-1 and Occludin protein expression is remarkably improved, the effect of relieving intestinal inflammation is achieved, and the traditional Chinese medicine composition can be used for preparing medicine for treating ulcerative colitis.

The invention provides a novel preparation method and application of hyperforin. According to the invention, all metabolism genes in the biosynthesis process of hypericin are analyzed for the first time in the field. The analysis process is pioneering work and comprises discovery of the gene and the enzyme coded by the gene, functional demonstration and analysis of the hyperforin produced by using yeast and tobacco as biological chassis. The invention lays a foundation for industrial production of the hypericin and the intermediate thereof.

The invention provides eyedrops based on a multifunctional peptide composition, a preparation method of the eyedrops and application of the eyedrops to treatment of diabetic retinopathy, and belongs to the technical field of eyedrops. The eye drops contain S-acetyl-L-glutathione, fisheye extracted peptide, hyperforin perforatum flower extracted peptide, aesculus hippocastanum leaf extracted peptide and other active ingredients. Wherein the fisheye extracted peptide is a small-molecule extracted peptide obtained by sequentially carrying out graded enzymolysis on snow fisheye through trypsin and serrapeptase. The hyperforin perforatum flower extracted peptide is a small-molecule extracted peptide obtained by sequentially carrying out graded enzymolysis on hyperforin perforatum flowers through bromelain, serrapeptase and nattokinase. The aesculus hippocastanum leaf extracted peptide is a small molecule extracted peptide obtained by performing common enzymolysis on aesculus hippocastanum leaves through papain and ficin. The multifunctional peptide composition disclosed by the invention exerts the portability of eyedrops in treating diabetic retinopathy, and also has safe and efficient treatment effects.

The application belongs to the technical field of medicines, and particularly relates to application of hyperforin in preparation of medicines for treating inflammatory bowel disease, and proves that hyperforin treatment can increase the colon length of a DSS-induced mouse colitis model, improve the pathological structure and clinical symptoms of the colon tissue of the model mouse, and significantly up-regulate ZO-1 protein and improve the levels of related inflammatory factors such as TNF-alpha, IL-6 and IL-1beta, and has significant anti-ulcerative colitis activity, and the hyperforin can provide a new approach for preparing medicines for treating ulcerative colitis in the future.

The invention belongs to the technical field of medicines, and discloses hypericum perforatum isopentenyl transferase and application thereof. In particular to novel isopentenyl transferase, a nucleic acid sequence for coding the transferase, an expression vector and a recombinant cell for producing the transferase, and further relates to application of the isopentenyl transferase in preparation of a hypericin biosynthesis precursor.