7 results about "Increased sleep" patented technology

The invention provides a nerve-soothing and sleep-aiding compound for improving sleep quality and application of the nerve-soothing and sleep-aiding compound. The nerve soothing and sleep aiding compound for improving sleep quality comprises the following components in parts by weight: 10-30 parts of a spina date seed extract, 5-15 parts of a polygala tenuifolia extract, 2-5 parts of sandalwood, 2-3 parts of bergamot, 2-3 parts of corydalis tuber, 1-2 parts of albizia flower, 1-2 parts of chamomile, 2-3 parts of lavender, 3-5 parts of sweet orange and 8-20 parts of a poria cocos extract. According to the nerve-soothing and sleep-aiding compound for improving the sleep quality and the application thereof, the nerve-soothing and sleep-aiding compound adopts various natural plant extracts and functional components, is safe and free of side effects, does not generate drug dependence and drug resistance after being used for a long time, is suitable for being used by people with various sleep disorders, and is free of toxic and side effects. According to the compound, through the synergistic effect of various components, the sleep time can be remarkably shortened, the sleep time can be prolonged, the sleep depth can be improved, the sleep quality can be effectively improved, and the compound has a good improvement effect on sleep disorders caused by pressure, anxiety and the like.

The present application provides the use of glycerophosphoric acid or a pharmaceutically acceptable salt thereof in the preparation of a composition for improving sleep, which can improve sleep from at least one of the following three aspects: increasing total sleep time, preventing sleep fragmentation, and increasing sleep depth.

The present invention addresses the problem of providing: a novel alkyne derivative or a pharmaceutically acceptable salt thereof; and a medicine containing said compound as an active ingredient.　This alkyne derivative or a pharmaceutically acceptable salt thereof exhibited an activity characteristic with respect to an α1 subunit in a GABAAα1β2γ2PAM test, showed, like eszopiclone, a decrease in the awake period and the REM sleep period, an increase in the Non-REM sleep period, and shortening of sleep onset latency, in a sleep test, and showed a weaker bitterness than eszopiclone in a bitterness test. Therefore, this compound has an excellent characteristic in which bitterness is reduced compared to eszopiclone, and is useful as a medicine such as an agent for ameliorating or treating sleep disorders.

This invention relates to a levotetrahydropalmatine citrate, its preparation method, and its applications, belonging to the field of pharmaceutical technology. This invention provides a levotetrahydropalmatine citrate. Studies have shown that compared to other salt forms, the citrate form of levotetrahydropalmatine significantly improves its solubility. Furthermore, research has confirmed that levotetrahydropalmatine citrate can significantly reduce drug relapse preferences, with efficacy comparable to or even better than the injectable form, without causing significant adverse reactions and exhibiting good safety. Simultaneously, the sedative effect of levotetrahydropalmatine citrate is far superior to other salt forms. In addition, levotetrahydropalmatine citrate has therapeutic effects on sleep disorders, effectively shortening sleep onset time, increasing sleep duration, and improving sleep quality. Therefore, the levotetrahydropalmatine citrate provided by this invention has broad application prospects in the preparation of drugs for sedation, analgesia, treatment of sleep disorders, and treatment of drug addiction.

The invention discloses a composition of GABA (gamma-aminobutyric acid), tremella polysaccharide and theanine as well as a preparation method and application of the composition. The composition comprises a mixture of the tremella polysaccharide and the theanine and the GABA. The mass ratio of tremella polysaccharide to theanine in the mixture is 10: 1; the mass ratio of the mixture of the tremella polysaccharide and the theanine to the GABA is 150: 100. The invention proves that when the GABA and the mixture are compounded according to a specific proportion for use, the GABA and the mixture show a remarkable synergistic effect in the aspects of promoting falling asleep, maintaining sleep, increasing non-rapid eye movement sleep and resisting caffeine-induced awakening, and a solid experimental basis is provided for developing an efficient composite sleep-aiding product.

The present application relates to a glycopeptide for improving sleep and application thereof, and relates to the technical field of biological medicine. The glycopeptide can increase sleep duration, improve sleep stability, has the effect of improving sleep, and can also significantly improve the learning and memory ability of patients with insomnia.

To provide a composition having a new function using young barley leaves, against a background in which development of foods and beverages having a sleep-improving action using a naturally derived food material as a functional component is demanded in modern times.SOLUTION: The present inventors, in the course of studying functions possessed by young barley leaves, have found that young barley leaves exert an action of improving quality of sleep or an action of increasing sleep time, thereby completing the present invention.SELECTED DRAWING: None