75results about How to "Improve microenvironment" patented technology

The invention provides a southern red soil dry land deacidification soil conditioner and a preparation method thereof, and belongs to the technical field of soil conditioners. The preparation method comprises the following steps: embedding bacillus subtilis, bacillus licheniformis and bacillus amyloliquefaciens to prepare bacterial microspheres, adding the bacterial microspheres into gel formed by carboxymethyl chitosan and silk fibroin peptide to prepare sustained-release bacterial microsphere gel, uniformly mixing the sustained-release bacterial microsphere gel with porous silicon dioxide loaded with basalt and charcoal, and drying to prepare the acid-reducing soil conditioner for the southern red soil dry land. The acid-reducing soil conditioner for the southern red soil dry land not only improves the pH value of the soil, but also can loosen the soil and improve the air permeability of the soil to a certain extent, and promotes the absorption of crops to moisture and nutrient elements by improving the physical and chemical properties of the soil, so that the normal growth of the crops is ensured, and the acid-reducing soil conditioner has a wide application prospect.

The invention provides a stem cell exosome composition for treating erectile dysfunction and application thereof, the stem cell exosome composition comprises stem cell exosome and vasoactive intestinal peptide, and the amino acid sequence of the vasoactive intestinal peptide is shown as SEQ ID NO: 2. The amino acid structure of the vasoactive intestinal peptide is modified, so that the biological stability can be improved; the vasoactive intestinal peptide is combined with the adipose-derived mesenchymal stem cell exosome for use, so that the ED symptom can be relieved; the vasoactive intestinal peptide and the adipose tissue-derived stem cell exosome are combined for use, so that the expression level of cell factors can be adjusted, and the microenvironment of penis tissues can be improved.

The invention provides double-crosslinking acellular matrix hydrogel as well as a preparation method and application thereof, and belongs to the technical field of hydrogel. The preparation method comprises the following steps: (1) carrying out decellularization treatment on a porcine dermal layer to obtain a decellularized porcine dermal matrix, (2) putting freeze-dried powder of the decellularized porcine dermal matrix into an acidic pepsin solution, stirring and digesting, adjusting the concentration, adding 10xPBS, adjusting the pH value to obtain a pregel solution, and carrying out freeze-drying on the pregel solution to obtain the porcine dermal matrix freeze-dried powder. (3) putting gel formed by the pre-gel solution into a tannic acid solution for cross-linking to obtain mono-cross-linked acellular matrix hydrogel; (4) smashing the mono-cross-linked acellular matrix hydrogel, and mixing the smashed mono-cross-linked acellular matrix hydrogel with a glucose oxidase solution and a ferrous ion solution with the concentration of 0.1-10mg / ml to obtain a bi-cross-linked acellular matrix hydrogel precursor; 5, the double-crosslinking acellular matrix hydrogel precursor is placed under the condition of glucose with the concentration being 10-200 mg / dl to form the double-crosslinking acellular matrix hydrogel. The hydrogel prepared through the method can achieve the balance of safety, supporting performance and degradability, and is wide in application range.

The invention relates to a recycling technology of industrial tailings, in particular to a soil conditioner prepared from the industrial tailings, a preparation method of the soil conditioner and application of the soil conditioner in acid cultivated land improvement. The soil conditioner provided by the invention comprises the following components: powder formed by calcining a basic raw material and an additive and then crushing the calcined basic raw material and additive, the basic raw materials comprise the following components in parts by weight: 85-95 parts of phosphate tailings and 2-10 parts of plant straws; the weight part of the additive is 3-5 parts. According to the invention, phosphate tailings and crop straws can be used as main raw materials to prepare the acid soil conditioner, the preparation process is simple, the cost is low, the treatment effect is good, acid cultivated land can be treated, and the soil conditioner can also be applied as a calcium magnesium phosphate fertilizer.

The invention provides an anti-hair loss and anti-dandruff composition and a preparation method thereof, and belongs to the technical field of wash supplies. The anti-hair loss and anti-dandruff composition is prepared from the following raw materials: a plant raw material, a plant extract, a caffeine composition and an oil control composition, wherein the plant raw materials comprise the following raw materials in parts by mass: 5-20 parts of ginger root, 5-20 parts of black ginger root, 5-20 parts of alpinia japonica root, 1-3 parts of ligusticum wallichii, 5-10 parts of radix sophorae flavescentis, 2-4 parts of fructus cnidii, 1-5 parts of fructus viticis, 3-5 parts of saponin, 5-8 parts of soapberry peel, 1-5 parts of dandelion, 5-8 parts of polygonum multiflorum, 1-3 parts of mulberry, 3-6 parts of cacumen biotae, 3-6 parts of mulberry leaf, 7-10 parts of purslane and 1-4 parts of mangnolia officinalis; the plant extract is prepared from the following raw materials in parts by mass: 5 to 20 parts of aloe extract, 1 to 10 parts of herba menthae extract, 5 to 20 parts of fructus forsythiae fruit extract, 5 to 20 parts of tea leaf extract, 5 to 20 parts of herba centellae extract and 1 to 10 parts of cordyceps militaris extract. The composition prepared by the invention not only has good anti-dropping and anti-dandruff effects, but also has good stability.

The invention discloses a regulation and control method for recarburization and nitrogen fixation of newly-reclaimed desertification saline-alkali soil, which is characterized in that the soil microenvironment is improved by combined application of bio-organic fertilizer / charcoal and attapulgite fertilizer, and nitrogen fixation of soil in a growth period and improvement of a soil structure are realized by mixed sowing of gramineous green manure crops and leguminous green manure crops. And after the growth period ends, returning the green manure to the field to realize soil recarburization. According to the recarburization and nitrogen fixation regulation and control method for the newly-reclaimed desertification saline-alkali wasteland, the soil nutrient and carbon reserve can be remarkably improved, and compared with other green manure crops or combinations, the total nitrogen and organic carbon of the soil are remarkably improved after the method is implemented. Therefore, the method has important significance on recarburization, nitrogen fixation and fertilization regulation and control of newly-reclaimed desertification saline-alkali soil, and can provide a development idea for efficient development and utilization of saline-alkali sand and guarantee of agricultural production safety.

The invention belongs to the technical field of saline-alkali soil improvement, and relates to a coastal moderate-severe saline-alkali soil rain-fed dry-farming early-spring sesbania planting method which comprises the following steps: S1, deep rotation is performed on saline-alkali soil; s2, ridging, wherein ditching and ridging are conducted on the saline-alkali soil subjected to deep rotation; s3, punching holes in the ridge sides and forming water gathering pits arranged in a duckbilled shape, and then paving a mulching film on the water gathering pits; s4, holes are drilled in the side face of the water gathering pit in the vertical direction, a seeding channel is formed, then the sesbania seeds are sown into the seeding channel, the peripheries of the holes of the mulching film are covered with soil, a duckbilled structure is formed, and rainwater is guided by means of the mulching film to flow into the water gathering pit to be gathered; s5, forming a straw interlayer after the whole sesbania is returned to the field. Rainwater is gathered to the seeding channel through the mulching film, the amount of water capable of being absorbed by the sesbania seeds is increased, in addition, the mulching film can also achieve the effects of improving the soil temperature and preserving soil moisture, so that the sesbania can be planted in a rain-fed dry farming mode at the end of March, and the saline-alkali soil improvement period is shortened.

The invention provides a full-biodegradable composite film and a preparation method thereof. The full composite membrane comprises an outer layer, a middle layer and an inner layer, wherein the outer layer comprises modified calcium carbonate, PLA, PBAT and an epoxy chain extender; the middle layer comprises modified montmorillonite, PLA (polylactic acid), PBAT (poly (butylene adipate-co-terephthalate)), PPC (polypropylene carbonate) and an epoxy chain extender; the inner layer comprises PLA (polylactic acid), PBAT (poly (butylene adipate-co-terephthalate)), an epoxy chain extender and an optional anti-blocking agent. The preparation method of the raw materials of the middle layer comprises the following steps: (i) dividing an epoxy chain extender used by the middle layer into an epoxy chain extender A and an epoxy chain extender B, and mixing PPC, modified montmorillonite and the epoxy chain extender A to prepare a first master batch of the middle layer; (ii) mixing PLA, PBAT and an epoxy chain extender B to prepare a middle-layer second master batch; and (iii) uniformly mixing the middle-layer first master batch and the middle-layer second master batch, extruding and granulating to obtain a middle-layer raw material. The full-biodegradable composite film prepared by the preparation method disclosed by the invention is good in uniformity and quality.

The invention discloses a method for preparing a NaP molecular sieve / activated carbon composite material from coal gangue, belongs to the technical field of coal-series solid waste recycling, and aims to solve the technical problem that the alkali resistance and wear resistance of a coal gangue-based molecular sieve need to be further improved in the prior art. The method comprises the following steps: adding a crystallized molecular sieve into a vapor deposition device, carrying out vapor deposition to obtain a carbonized molecular sieve, and carrying out hot isostatic pressing to obtain the carbon-coated molecular sieve. And carrying out vapor deposition, hot isostatic pressing and oxidation liquid treatment, and finally cross-linking through a hydrophilic modifier to obtain the wear-resistant, alkali-resistant and hydrophilic composite molecular sieve.

The invention relates to an antibacterial anti-inflammatory blood vessel promoting time sequence microneedle and a preparation method thereof. The microneedle comprises a first microneedle mold, a second microneedle mold and a third microneedle mold which are arranged in sequence, the first microneedle mold is filled with a carrier material A, an antibacterial component and / or a traditional Chinese medicine component A; the second microneedle mold is filled with a carrier material B, an anti-inflammatory component and / or a traditional Chinese medicine component B; and the third microneedle mold is filled with a carrier material C and / or a vascular tissue regeneration promoting component. A good microenvironment is provided for tissue regeneration, the microneedle sequentially resists bacteria, resists inflammation and promotes vascular tissue regeneration, the microneedle conforming to the time sequence is beneficial to tissue regeneration, and the microneedle has a good application prospect.

The invention belongs to the technical field of medical materials, and particularly provides a 3D printing bone repair material and a preparation method thereof.The 3D printing bone repair material is prepared from PCL / MnO2 composite microspheres and SiN, PCL has good biocompatibility and biodegradability, the mechanical performance and bone induction performance of the 3D printing bone repair material are enhanced due to addition of SiN, and the 3D printing bone repair material has a good application prospect. MnO2 can release oxygen and manganese ions, and the manganese ions can promote calcium deposition, jointly promote cell infiltration, osteogenic differentiation and matrix mineralization, promote bone precursor cell proliferation, accelerate bone defect repair and promote bone regeneration, so that the bone regeneration rate is increased, and the bone regeneration rate is increased. The prepared 3D printing bone repair material has good mechanical performance, biocompatibility, antibacterial property and biodegradability, cell proliferation is promoted, and bone repair and bone regeneration are accelerated.

The invention provides an elastin essence capable of improving the toughness and elasticity of hair, and the elastin essence comprises the following components in percentage by weight: 0.00000005-0.05% of elastin (MW5000-10000), 0.0001-0.05% of hydrolyzed keratin (MW600), 0.0001-0.05% of hydrolyzed keratin (MW1000), 0.00005-0.05% of hydrolyzed keratin (MW1000), 0.00005-0.05% of hydrolyzed keratin (MW1000), 0.00005-0.05% The invention discloses a scalp nourishing essence, which is prepared from the following components in percentage by weight: 0.005 to 0.5 percent of hydrolyzed keratin (MW3000), 0.001 to 0.5 percent of hydrolyzed collagen (MW1000-2000), 0.000005 to 0.1 percent of arginine / lysine polypeptide (MW2500), 0.000005 to 5 percent of small fruit coffee protein peptide (MW 500 to 1000), 0.00001 to 0.1 percent of agilawood extract, 0.005 to 0.5 percent of PEG-6 caprylic acid / caprin, 0.05 to 0.3 percent of carbomer, 0.8 percent of phenoxyethanol, 0.15 percent of ethylhexylglycerin, 0.01 to 0.08 percent of sodium hydroxide and the balance of water. The elastin and various protein peptides are combined and arranged according to the molecular weight to form hierarchical permeation, repair and elastic support on the hair epidermal layer and the hair core layer, so that the hair is repaired, and the toughness and elasticity of the hair are improved.

The invention provides a skin care composition containing stem cell extract as well as a preparation method and application of the skin care composition, and belongs to the technical field of cosmetics. The method comprises the following steps: mixing and culturing the extracted urine-derived stem cells and pilose antler stem cells in a DMEM culture medium added with epidermal growth factors, cholera toxin, penicillin, streptomycin, transferrin, IL-2 and IL-15, then separating a culture solution to obtain mixed exosomes, mixed stem cells and extracellular matrixes, preparing the mixed stem cells into stem cell lipidosome, and preparing the stem cell lipidosome. Embedding the stem cell extract and the mixed exosome into titanium dioxide / silicon dioxide microspheres, adding into an extracellular matrix, and uniformly dispersing to obtain the skin care composition containing the stem cell extract. The skin care composition containing the stem cell extract prepared by the invention can obviously prolong the preservation period of stem cells and exosomes and improve the repair and improvement of the stem cells and the exosomes on skin, and the prepared composition has better effects of resisting aging, whitening, promoting skin elasticity, resisting wrinkles and the like, and has a wide application prospect.

The invention discloses a body acne-removing composition containing guaiacol extract and application of the body acne-removing composition, and relates to the technical field of cosmetics. The invention provides an acne removing composition. The acne removing composition is prepared from the following components in parts by weight: 0.01 to 0.1 part of saponin A, 0.1 to 1 part of saponin B, 5 to 15 parts of buckwheat extract, 1 to 10 parts of cassia occidentalis seed extract and 1 to 10 parts of guaiacol extract. The saponin A comprises asperuloside and aucubin, the saponin B is ziyuglycoside, and the ziyuglycoside comprises ziyuglycoside I and ziyuglycoside II. When the saponin B and the saponin A cooperate with the buckwheat extract, the guaiacol extract and the cassia seed extract, on one hand, the whole acne-removing composition has excellent effects of removing heat, detoxifying and slowing down heat sensation, and can effectively prevent acne from growing on the skin; on the other hand, permeation of active substances in a skin barrier is promoted, dry skin is relieved, healing and repairing of existing acnes are accelerated, and the grease amount of the skin and the surface roughness of the skin are further improved.

The invention provides a traditional Chinese medicine composition for treating qi-yin deficiency type pulmonary nodule and a preparation method and application thereof, and belongs to the technical field of traditional Chinese medicine preparations. The traditional Chinese medicine composition is prepared from the following components in parts by weight: 10-30 parts of sun-dried ginseng, 15-45 parts of celandine, 10-40 parts of lily and 10-40 parts of fructus trichosanthis. The traditional Chinese medicine composition disclosed by the invention has an exact curative effect on patients with qi-yin deficiency type pulmonary nodules, and can reduce and stabilize the size of the pulmonary nodules and reduce the malignant risk probability of the patients with the pulmonary nodules; the qi-yin deficiency type clinical symptoms such as fatigue, cough and dry mouth of a patient can be obviously relieved; the release of inflammatory factors of the body is effectively improved, the immune cell microenvironment is regulated, the precancerous soil of a patient is improved, and the clinical application prospect is wide.

The invention discloses a preparation method and application of a porous GelMA microneedle for delivering AIE molecules based on HSF derived exosome. The preparation method comprises the following steps: S1, preparing TTMN molecules; s2, dispersing DPPC and Chol in chloroform, performing water bath evaporation at 50 DEG C to form a thin film, hydrating the thin film in PBS, incubating to enable DPPC and Chol to form a liposome structure again, and uniformly dispersing TTMN molecules in the liposome structure to obtain TL; s3, extracting an exosome from the HSF cells; s4, loading the TL into the exosome by utilizing an electroporation technology, so as to obtain TE; s5, preparing the GelMA; and S6, mixing the GelMA with the TE, so that the TE is uniformly dispersed in the GelMA to obtain a mixed solution, injecting the mixed solution into a microneedle mold, and irradiating with 405nm laser to obtain the porous GelMA microneedle. According to the invention, high-efficiency treatment of hypertrophic scars is realized, and the system has a remarkable drug delivery effect, an innovative photodynamic therapy, a high-efficiency scar tissue remodeling effect and good biological safety and stability, and has important clinical application value and market prospect.

The invention discloses a hair loss prevention and hair growth composition, a preparation method thereof, and a hair care cosmetic containing the hair loss prevention and hair growth composition, which is composed of the following components: 1-2 parts of ginger root extract; 1-2 parts of Polygonum multiflorum extract; 2.58-8.3 parts of skin auxiliary conditioner; 0.56-2.1 parts of hair auxiliary conditioner; 0.1-2 parts of preservative; 5-15 parts of moisturizer; 70-85 parts of water. The above composition can effectively improve the hair microenvironment, inhibit sebum secretion, and prolong the hair survival cycle through the cooperation of the skin auxiliary conditioner and the ginger root extract. While comprehensively preventing hair loss, the hair auxiliary conditioner and the Polygonum multiflorum extract are used to regulate the blood supply of the key parts of the hair follicle cycle growth, enhance the vitality of the hair, and strengthen the hair roots, thereby achieving a comprehensive solution to various problems such as seborrheic alopecia, neurotic alopecia, diffuse alopecia, and nutritional alopecia.

The embodiment of the invention discloses a rice seed coating agent based on halloysite nanotubes as well as a preparation method and application thereof, relates to the technical field of seed coating agents, and aims to solve the technical problem that an existing seed coating agent is difficult to meet application requirements. The rice seed coating agent based on the halloysite nanotubes comprises the following components in parts by weight: 5-20 parts of halloysite nanotubes, 5-20 parts of urea, 1-5 parts of an adhesive, 1-2 parts of calcium chloride, 1-2 parts of an insecticide and 2-3 parts of a plant growth regulator. The halloysite seed coating agent provided by the invention is simple in preparation process, and a fertilizer or a pesticide is loaded by utilizing a hollow tubular structure and an interlayer pore structure of the halloysite nanotube. Through combination of multiple functional components, the germination rate of rice seeds can be increased, growth and development of seedlings are promoted, the yield increasing effect is achieved, and the development requirement of green agriculture is met.

The invention discloses a method for improving cell growth and expression by changing an iron form in a culture medium, and relates to the technical field of cell culture, the culture medium comprises a basic culture medium, a supplemented culture medium and an iron source; wherein the iron source is FeCl3, the basic culture medium and the supplementary culture medium are commercially available culture media, the iron source is not added or removed, and the culture media further contain a three-dimensional culture material; the redox balance of the culture medium can be maintained, oxidative stress damage of cells is prevented, hydrolysis or precipitation is not prone to occurring, the preparation process of the culture medium is simplified, and the requirements of cell growth and expression are met.

The invention provides a traditional Chinese medicine preparation for preventing and treating myelosuppression after chemotherapy, and relates to the field of traditional Chinese medicine pharmacy, the traditional Chinese medicine preparation is prepared from 1-15 parts of deer-horn glue, 1-10 parts of astragalus membranaceus, 1-10 parts of cassia twig, 1-10 parts of pseudo-ginseng, 1-10 parts of immature bitter orange, 1-10 parts of rhizoma anemarrhenae and 1-10 parts of golden cypress, and the traditional Chinese medicine preparation has the effects of invigorating qi and blood, promoting blood circulation to remove blood stasis, relieving swelling and pain and the like. The traditional Chinese medicine preparation disclosed by the invention can reverse myelosuppression caused by 5-FU chemotherapy by improving the peripheral hemogram of a chemotherapy mouse and pathological injury of bone marrow. In addition, the traditional Chinese medicine preparation can improve the 5-FU chemotherapy effect by increasing the 5-FU tumor inhibition rate, inhibiting tumor weight and tumor volume and promoting tumor tissue necrosis. The traditional Chinese medicine preparation disclosed by the invention is combined with a chemotherapeutic drug 5-FU for application, has certain effects of enhancing effects and reducing toxicity, and is expected to be developed into a drug for preventing and treating myelosuppression after chemotherapy.

The invention relates to the technical field of medical biological materials, and discloses a mussel mucin-chondroitin sulfate composite hydrogel and a preparation method and application thereof, and the preparation method comprises the following steps: respectively preparing a mussel mucin aqueous solution and a chondroitin sulfate aqueous solution; the mass volume concentration of the mussel mucoprotein aqueous solution is 1%-10%, the mass volume concentration of the chondroitin sulfate aqueous solution is 1%-10%, the mass ratio of the mussel mucoprotein to the chondroitin sulfate is 3: 1-1: 3, the two solutions are mixed and stirred or oscillated under the conditions that the temperature is 4-37 DEG C and the pH value is 7.0-9.0, a cross-linking reaction is conducted, and hydrogel is formed; the cross-linking mode is physical cross-linking, chemical cross-linking or physical-chemical dual cross-linking; according to the invention, excellent tissue adhesion, injectability, self-healing property and biodegradability are realized, cell adhesion and proliferation can be effectively promoted, and the gel is suitable for various medical beauty scenes such as skin filling, wound repairing and anti-aging nursing.

This invention discloses a near-infrared light-exciteable composite nanosheet, its preparation method, and its applications, belonging to the field of biomedical technology. The method includes the following steps: mixing epigallocatechin gallate with a Ti3C2 nanosheet dispersion, ultrasonically reacting, adding silver salt, and continuing stirring in the dark; after the reaction is complete, washing and separating to obtain MXene-EGCG@Ag composite nanosheets. The composite nanosheets provided by this invention possess near-infrared light-exciteable properties and can be used to prepare medically acceptable dosage forms such as hydrogels for the treatment of periodontitis. The preparation method provided by this invention is simple, the raw materials are readily available, and it exhibits significant antibacterial and anti-inflammatory effects, enabling further widespread application.

The invention relates to a wound repairing composition and a preparation method thereof. The wound repairing composition comprises the following components: modified hyaluronic acid containing RGD peptide and collagen. The wound repairing composition can greatly improve the skin bioavailability of collagen, improve the moisturizing and repairing effects of the composition acting on the skin, and accelerate the wound healing time.

According to the 3D printing flexible hydrogel device for pancreas islet transplantation and the preparation method and application of the 3D printing flexible hydrogel device, functional ink containing N-acryloylurea amine and carboxylic acid betaine carbamido acrylate is developed, the digital light processing 3D printing technology is adopted, the ink formula and printing parameters are optimized, and the pancreas islet transplantation efficiency is improved. The 3D printing flexible hydrogel device for pancreas islet transplantation, which has excellent flexibility, biocompatibility and a controllable pore structure, is prepared. According to the device, a complex geometric structure of the hydrogel device is constructed layer by layer through a DLP printing technology, and accurate control over the porosity, the size and the shape of the device is achieved; the prepared hydrogel device can significantly improve the microenvironment after islet cell transplantation, provide effective protection, and improve the survival rate and transplantation success rate of islet cells.

The invention provides a probiotic culture medium and a method for preparing a probiotic preparation, and belongs to the technical field of microbial culture. According to the preparation method, the probiotic culture medium is firstly prepared, the probiotic compound is obtained by utilizing the probiotic culture medium and bifidobacteria, and then the dietary fiber compound, the quercetin compound and the liquorice-rhizoma cyperi compound are used together, so that the probiotic preparation is obtained, and the preparation can effectively improve related symptoms of intestinal tracts, stomachs and respiratory tracts.

The invention discloses a transplanting microenvironment construction device and an application method thereof, and aims to improve the seedling standing rate and the qualified rate of rape blanket seedling crops. According to the device, the land preparation device is innovatively designed, ridge surface micro ridges are formed, ridge planting of the planting device is facilitated, and the crop seedling rate and the qualified rate are increased. The device has the soil crushing and growth gathering functions, soil softening and ventilation are facilitated, and a good environment is provided for crop growth. The planting device can accurately control the planting depth and the planting angle, and the stability and the consistency of the growth environment in the seedling stage are ensured. The application method is simple and easy to implement, can be widely applied to agricultural production, and has important significance on improving the production efficiency and quality of crops such as oilseed rape.

The invention relates to the technical field of vegetable cultivation, and discloses a vegetable full-coverage ecological efficient cultivation technology which comprises the following steps: step 1, selecting and designing a functional composite mulching film which has the functions of temperature and humidity regulation, pest control, accurate nutrient release and soil protection, and the design of the mulching film comprises a multi-layer structure, each layer has different functions; and step 2, performing plastic film mulching: laying the functional composite plastic film on a vegetable planting area to cover the whole soil surface so as to form a full-coverage cultivation environment. Through optimization of a cultivation environment and accurate nutrient management, the growth efficiency and yield of crops are remarkably improved, a full-coverage cultivation technology and an intelligent fertilization system are combined, so that the crops can obtain appropriate moisture, illumination, nutrients and other elements in different growth stages, and thus healthy growth and disease resistance of the crops are enhanced; the overall quality and the market competitiveness of the vegetables are improved.

The application discloses a tracheotomy fixing device and a control method thereof, and relates to the field of medical devices.The device comprises a fixing base assembly, an adjustable fixing belt system, an intelligent monitoring and adjusting module, a pressure sore prevention auxiliary structure and a wireless communication module.The fixing device can realize real-time acquisition of pressure data in the fixing area through a pressure sensor array, analysis and processing of the pressure data by an intelligent control unit, automatic adjustment of the tightness of the fixing belt by driving an electric adjusting actuator when an abnormal pressure trend is identified, and output of graded alarm information by an alarm unit, so that stable fixation of a tracheal cannula and safe management of pressure are realized.The fixing device can also improve the skin contact environment through a pressure reduction and air permeation structure, reduce the risk of pressure sores, support data interaction with a nursing terminal, and improve nursing efficiency.The application can realize a change from passive fixation to active safety management, and has good clinical application value.

This invention relates to a multifunctional bioactive dental bulk filling composite resin and its preparation method. The composite resin comprises an organic resin matrix and an inorganic filler; the organic resin matrix comprises polymerizable resin monomers and a photoinitiator system, the polymerizable resin monomers comprising dimethacrylate monomers and E-POSS; the inorganic filler comprises nMgO and sSiO2 with a silanized surface. The preparation method includes the following steps: preparing nMgO powder using a sol-gel method combined with a gradient calcination process; preparing submicron-sized sSiO2 using the Stöber method and subjecting it to surface silanization treatment to obtain silanized sSiO2; mixing the polymerizable resin monomers, E-POSS, and the photoinitiator system, stirring in the dark until a homogeneous resin matrix is ​​formed; adding the obtained nMgO and silanized sSiO2 to the resin matrix in a specific ratio and mixing and dispersing evenly to obtain an uncured paste-like composite resin.

The invention relates to a high-safety ring main unit, and relates to the technical field of electrical equipment, the high-safety ring main unit comprises a cabinet body, the cabinet body is provided with an overheat pressure relief device and a pressure balance device, and a driving component of the overheat pressure relief device is a driving element made of shape memory alloy to control a pull plate to slide to open a flashboard to release hot pressing in the cabinet body. A flexible diaphragm of the pressure balancing device is matched with the cabinet body and the thermal pressure relief device to form an airtight space, and the internal and external pressure difference of the box body is compensated through deformation after the overheating pressure relief device acts to relieve pressure. The ring main unit achieves the technical effects of effectively releasing the hot pressure in the cabinet body, compensating the pressure difference inside and outside the box body, improving the safety of the ring main unit and the like.