60 results about "Thermus thermophilus" patented technology

The invention provides an X-ray crystal structure of the 30S ribosome, obtained from Thermus thermophilus 30S subunit, having a tetragonal space group P41212 with unit cell dimensions of a=401.4±4.0 Å, b=401.4±4.0 Å, c=175.9±5.0 Å. An advantageous feature of the structure is that it diffracts beyond 3 Å resolution. The invention also provides a crystal of 30S having the three dimensional atomic coordinates of the 30S ribosome, the coordinates being provided in Tables 1A and 1B. The data may be used for the rational design and modelling of inhibitors for the 30S ribosome, which have potential use as antibiotics.

To provide a skin care composition having effects of anti-inflammation, moisturization, and whitening of skin yellowing.SOLUTION: The present invention discloses application of a fermentation product in preparing reagents for anti-inflammation, moisturization, or whitening of skin yellowing, the fermentation product is prepared from thermus thermophilus and yeast through fermentation co-culture, a thermus thermophilus and yeast co-fermentation method comprising the following steps: firstly, carrying out bacterium increase fermentation once or multiple times on yeast at low temperature under acidic condition after a logarithmic phase, increasing the temperature of a fermentation liquid to a high temperature from a low temperature, adding thermus thermophilus, and carrying out secondary fermentation under alkaline condition. The method includes the steps of: (1) performing one-time or multi-time fermentation to saccharomyces cerevisiae at low temperature under acidic condition, thus reproducing the yeast; and (2) when the yeast is in a later period of a logarithmic phase, increasing the temperature, inoculating the thermus thermophilus, and performing second fermentation under alkaline condition, thereby producing a fermentation product.SELECTED DRAWING: Figure 1

The invention discloses a Thermus thermophilus laccase, engineering bacteria, recombinant laccase and application thereof. The amino acid sequence of the Thermus thermophilus laccase is shown in Seq No.2. The DNA sequence encoding the above laccase is shown in Seq No.1. The DNA can be used in constructing a Pichia pastoris expression system. The recombinant Pichia engineering strain is obtained by linearizing the expression vector pHKFA1-lacTT and then transforming Pichia pastoris. The recombinant laccase is obtained by fermenting the above-mentioned recombinant Pichia pastoris engineered bacteria. The recombinant laccase has laccase activity and high temperature resistance, and can be used in the decolorization of dyes, especially the decolorization of azo dyes and anthraquinone dyes, and the decolorization rate can even reach 100%.

The invention discloses a method for combined fermentation of thermophilic thermus and saccharomyces. The method comprises the following steps: (1) first fermenting Saccharomyces cerevisiae once or more times under medium temperature and acidic conditions, and then fermenting the saccharomyces Bacteria enrichment; (2) Waiting for the yeast to be in the late logarithmic growth phase and then raising the temperature, inoculating Thermus thermophilus and carrying out the second fermentation under alkaline conditions to obtain the fermentation product. By using the method of the invention, some active ingredients of thermophilus Thermus can be significantly improved, especially the content or activity of some active ingredients used in cosmetics is increased.