The invention discloses a supervisory control method for producing trehalose by a double-enzyme method. The supervisory control method comprises the following steps of firstly mounting a near-infrared real-time monitoring and control system; collecting starch liquefied liquid, measuring a DE (Dextrose Equivalent) value by using a Fehling's reagent method, collecting catalysis liquid, measuring a pH (potential of Hydrogen) value by using a pH meter, measuring the content of the trehalose by using high performance liquid chromatography, associating with a correspondingly collected near-infrared spectrum, establishing a quantitative model of changes of the DE value, the content of the trehalose and the pH value in a production process, and correcting; afterwards, quickly detecting the DE value, the content of the trehalose and the pH value in the production process by utilizing the established model, and stabilizing the DE value to be 8 to 20 and stabilizing the pH value to be in the range, in which the activity of malto-oligosaccharide based trehalose synthase-MTSase and malto-oligosaccharide based trehalose hydrolase-MTHase is optimal, by utilizing a control system. The method can be used for monitoring the DE value of starch liquid and the content of the trehalose in reaction liquid in real time and can also used for automatically controlling the change of the pH value and the content of the trehalose and the result is accurate and reliable.