6 results about "Skin infection" patented technology

The application belongs to the technical field of bioengineering, and relates to a marine-derived antibacterial peptide FP2606 and a use of the marine-derived antibacterial peptide FP2606 in preparation of a skin antibacterial drug. Streptomyces globisporus The application also provides a DNA molecule encoding the antibacterial peptide, a recombinant expression vector and an engineering strain, and realizes high-efficiency heterologous expression of the FP2606 in vitro. Experimental verification shows that the antibacterial peptide FP2606 has strong bacteriostatic activity on common pathogenic bacteria causing skin infection of children, has extremely high biological safety, has no hemolytic activity, no skin cell toxicity and no skin irritation, perfectly adapts to the physiological characteristics of the tender skin of children, and can be widely applied to preparation of a skin external antibacterial preparation for children, a skin infection prevention and treatment drug for children and a skin barrier care product for children.

Antimicrobial peptides of general formula XX1X2C X3X4X5CXXX&XgCYX10X11CX12X13 are provided. Also provided are certain formulations containing these peptides and methods of using these peptides for treating skin infections in an animal in need thereof. 20 24 21 96 45 12 S ep 2 02 4 S e p 2 0 2 4 A N T I M I C R O B I A L P E P T I D E S A N D M E T H O D S O F U S I N G S A M E A B S T R A C T 2 0 2 4 2 1 9 6 4 5 1 2

Provided herein are compositions for treating epidermolysis bullosa (EB). Also disclosed are methods for treating skin in a human with EB. The methods comprise providing a composition comprising a biopolymer and one or more pharmaceutically acceptable excipients; and topically applying, or instructing to topically apply, the composition to the skin of a human with EB. In certain embodiments, the composition is topically administered to treat non-healing wounds, chronic wounds, or diseased skin in a patient with EB, to reduce the likelihood of skin infection, to reduce the likelihood of scarring, to prevent or reduce the risk of an infected skin blister, to treat an intact blister on the skin, to treat skin dysbiosis, to alter bacterial diversity of the skin microbiome, or to improve the quality of life of a subject with EB.

Provided herein are compositions for topical application to a subject for the treatment of epidermolysis bullosa (EB). Also disclosed are methods for treating skin in a human with EB. The methods comprise providing a composition comprising fusidic acid and one or more pharmaceutically acceptable excipients; and topically applying, or instructing the topical application of, the composition to the skin of a human with EB. In certain embodiments, the composition is topically administered to treat non-healing wounds, chronic wounds, or diseased skin in a patient with EB, to reduce the likelihood of skin infection, to reduce the likelihood of scarring, to prevent or reduce the risk of an infected skin blister, to treat intact blisters on the skin, to treat skin dysbiosis, to alter bacterial diversity of the skin microbiome, or to improve the quality of life of a subject with EB.

The present invention relates to a composition for use in the treatment of a fungal infection comprising a polymer capable of forming nanoparticles and terbinafine, or derivative or salt thereof, wherein the nanoparticles are formed with and / or in the presence of terbinafine, or derivative or salt thereof, and where the composition comprises: a) a ratio of terbinafine, or derivative or salt thereof, to polymer in the range of about 1:2 to 1:4; and b) up to about 30% (v / v) alcohol. The composition is particularly suited as a topical treatment for fungal nail or skin infections. The invention also relates to methods of producing such compositions and combinations which can be used to produce said same.

The Formulation describes the preparation of an antimicrobial cream which comprises of humic acid, water and petroleum jelly. The cream acts as a potent antifungal and antibacterial agent and is effective in many skin infections. In clinical trials the cream was found to be effective and well tolerated and free from irritative and allergic reactions.