216 results about "Skin problem" patented technology

The invention relates to the technical field of oxidation resistance, in particular to a glutamic acid derivative, a preparation method thereof and application of the glutamic acid derivative in rhythm gene regulation and oxidation resistance. The glutamic acid derivative has a structure as shown in a formula I. The glutamic acid derivative provided by the invention can up-regulate expression of CLOCK protein and Per3 protein, can inhibit ROS in cells and up-regulate expression of Nrf2, and can be applied to relieving skin problems caused by disorder of circadian rhythm. # imgabs0 #

The invention discloses a personalized 3D printing mask based on MRI (Magnetic Resonance Imaging) reconstruction and a preparation method thereof. The method comprises the following steps: scanning a human face by using magnetic resonance equipment to obtain human face MRI data, and generating a human face three-dimensional model according to the human face MRI data; taking the human face three-dimensional model as a reference to generate a three-dimensional mold which is completely fitted with the face contour; extracting physiological parameters of the human face skin from the human face MRI data by adopting a medical image platform, and performing quantitative analysis on the physiological state of the human face skin according to the physiological parameters to obtain a quantitative analysis result; and adopting biological 3D printing equipment, taking a three-dimensional mold as a carrier, and combining the quantitative analysis result to carry out 3D printing, so as to obtain the 3D printing mask. The 3D printing facial mask prepared by the method can be highly fit with the facial contour of a human body, and skin problems of different facial areas can be accurately nursed.

The invention discloses a composite gel for skin correction and a preparation method thereof. The composite gel is formed by dissolving sodium hyaluronate, epidermal growth factors and a protein stabilizer in a buffer system; the content of the sodium hyaluronate is 1.0-50.0 g / L, the content of the epidermal growth factor is 1000-30000 IU / mL, and the content of the stabilizer is 5.0-100.0 mg / L; the pH value of the buffer system is 6.5-7.5. The preparation method comprises the following steps: S1, dissolving sodium hyaluronate and a stabilizer in a buffer system under a sterile condition, and stirring to obtain gel A; s2, adding epidermal growth factors into the gel A, and stirring to obtain the composite gel. The composite gel disclosed by the invention can activate epithelial fibroblasts, update and reconstruct ECM and maintain the stability of an ECM microenvironment. The composite gel disclosed by the invention integrates the functions of supplementing lost extracellular matrix, increasing the number of cells and promoting synthesis of collagen by a traditional filling material, can solve the skin problems caused by various factors, and achieves the effect of correcting the skin.

This needle assembly for a laser treatment directly radiates laser into skin by using a needle having an optical fiber inserted therein, and thus may effectively improve various skin problems such as elasticity, wrinkles, inflammation, and acne. In addition, local regional treatment is enabled so that side-effects resulting from the laser irradiation may be minimized and the pain of a subject being treated may be reduced. The needle assembly for a laser treatment comprises: a needle part comprising a hollow needle and a needle support part having one end portion of the needle passing therethrough and fixed therein; an optical fiber positioned inside the needle along the length direction such that one end of the optical fiber is not exposed to the outside of the tip portion of the needle; an optical fiber support part connected to the other end of the one end of the optical fiber; and a guide component positioned between the needle support part and the optical fiber support part so as to guide the insertion of the optical fiber into the hollow of the needle.

The invention provides a composition for repairing a skin barrier as well as a preparation method and application thereof, and relates to the technical field of cosmetics. The invention discloses a composition for repairing a skin barrier. The composition comprises ceramide NP1, ceramide AP, ceramide EOP, asiaticoside and DNA sodium. The composition is used for repairing skin from related proteins such as endogenous and endogenous injury, inflammatory factor inhibition, light injury, skin cuticle barrier and the like, and can deeply resist inflammation, relieve and maintain stability in an endogenous and endogenous two-way manner, and repair the damaged skin barrier in a multi-level and multi-dimensional manner, so that the skin problems such as skin dryness, roughness, desquamation, redness and swelling, pruritus and the like are improved.

The invention discloses an intelligent analysis system for a facial skin laser operation, and aims to provide a precise laser treatment scheme for a patient through intelligent analysis and personalized recommendation. The system comprises a data acquisition module, a preprocessing and analysis module, an intelligent diagnosis module, a treatment scheme recommendation module and a feedback and monitoring module. A high-definition camera, an infrared sensor, an ultrasonic scanner and other devices are used for collecting facial skin data of a patient, a deep learning algorithm is used for accurately diagnosing skin problems, and a personalized laser treatment scheme is generated according to a diagnosis result. In addition, the system can track the treatment effect in real time and adjust the treatment scheme according to the recovery condition, so that the safety and effectiveness of treatment are ensured. According to the system, the accuracy and individuation level of laser treatment can be greatly improved, the uncertainty and side effects in a traditional laser treatment method are improved, and the treatment effect and satisfaction degree of a patient are improved.

The invention discloses a phototherapy mask treatment method, device and equipment based on deep learning. Comprising the steps of collecting a face image of a target user, and performing segmentation and classification on the face image based on a deep learning model to generate a visual result; performing statistical analysis on the visualization result to generate a skin analysis result, and determining a target phototherapy mode according to the skin analysis result; and starting a phototherapy mask to treat the target user based on the target phototherapy mode. Personalized analysis can be carried out according to the skin features of the target user through the deep learning model, pertinence is better, different skin areas and features are distinguished through segmentation and classification, a visualization result has higher reference value, and skin problems can be visually presented to the user. Finally, based on a quantized skin analysis result, the most suitable target phototherapy mode can be accurately matched according to specific skin problems and grades of different users, the accuracy and effectiveness of treatment are improved, and the user experience is improved.

The invention discloses a composition and a cosmetic with anti-allergy, itching-relieving and redness-removing effects. The composition is prepared from the following raw material components: a herba centellae extract with madecassoside content of not less than 85wt%, a dendrobium officinale stem extract and dihydrooat acyl o-aminobenzoic acid. The composition comprising the three components is added into the cosmetic, so that the cosmetic has good system stability, also has enhanced anti-allergy, itching-relieving and red-removing effects, and can improve skin problems from multiple dimensions.

The application belongs to the technical field of microorganisms and particularly relates to a Bifidobacterium adolescentis beneficial to skin, a derivative of the Bifidobacterium adolescentis and application of the Bifidobacterium adolescentis and the derivative. The derivative of the Bifidobacterium adolescentis has significant antioxidant and anti-inflammatory effects, can inhibit pathogenic bacteria of acne and other common skin infections such as Propionibacterium acnes, Staphylococcus aureus and Malassezia furfur, can eliminate pathogenic bacteria, can inhibit skin lipid accumulation, can avoid follicle blockage, and can improve skin problems in multiple directions, especially acne skin problems.

The invention discloses an ancient moxibustion beauty method based on moxibustion therapy and facial acupoint stimulation and a matched device, relates to the technical field of traditional Chinese medicine beauty, and aims at improving facial complexion and conditioning skin through natural physical means. The device comprises a shell, a wooden plug cap, a vent hole, a stone needle base and the like, and a round hole and a stone needle tank opening are formed in the end face of the stone needle base to ensure uniform permeation of heat. The temperature is controlled by placing the moxa cones and adjusting the ventilation holes, and dynamic needle warming moxibustion stimulation is achieved by fitting face acupuncture points with the help of the curved surface design of the bottoms of the stone needles. The traditional Chinese medicine composition has the effects of promoting blood circulation, relieving edema, regulating qi and blood and relieving nerves, and finally, the problems of dull and loose skin color and the like are radically solved. Chemical stimulation is abandoned, far infrared rays are released through the natural stone needle material, the traditional Chinese medicine meridian theory is combined, beauty maintaining and young keeping from inside to outside are achieved, and safety, adaptability and long-term effect are achieved.

The composition is composed of a herbal medicine alcohol extract and an alcohol solvent, the herbal medicine comprises Jinfo grass, radix angelicae, solidago decurrens, oldenlandia diffusa, fructus kochiae, fructus cnidii, bletilla striata, radix clematidis, cortex dictamni, portulaca grandiflora and gallnut, and the herbal medicine is scientifically proportioned according to the principle of monarch, minister and guide. The preparation method comprises the following steps: processing medicinal materials such as fructus cnidii, crushing, soaking with high-concentration alcohol according to a specific ratio, extracting, and finally filling into a spray bottle. The traditional Chinese medicine composition integrates multiple functions of disinfection, hemostasis, detumescence, pain relieving, itching relieving and the like, is suitable for multiple skin problems such as traumatic bleeding, burns and scalds, eczema and mosquito bites, and can be used for skin disinfection during epidemic situations so as to reduce epidemic risks. The product takes effect quickly, is convenient to use and is safe and effective, and the preparation process integrates tradition and efficiency.

This invention discloses a Tibetan bath composition compound and its preparation method, relating to the field of daily chemical products technology. The Tibetan bath composition compound consists of a ternary complex of scutellaria baicalensis hydroxypropyl-β-cyclodextrin nanoshell powder, Bacillus subtilis, Tibetan medicine composition, starch, anhydrous citric acid, sodium bicarbonate, calcium citrate, crospovidone, and magnesium stearate. Bacillus subtilis is used to ferment the ternary complex of scutellaria baicalensis hydroxypropyl-β-cyclodextrin nanoshell powder to obtain a fermentation-modified porous carrier, which is then loaded with the Tibetan medicine composition to form a Tibetan medicine inclusion powder. This not only achieves efficient drug delivery through a triple mechanism of biomodification, metabolite synergy, and structural optimization, but also forms a quaternary system with Terminalia chebula. The effervescent effect also enhances the penetration of Tibetan medicine components, which is beneficial for better exerting the antibacterial and anti-inflammatory effects of active substances, and significantly improving fungal infections and eczema-related skin problems.

The invention discloses application of a circium japonicum extract. The circium japonicum extract is applied to preparation of products for preventing skin problems caused by cortisol unbalance. The invention also relates to application in preparation of products for relieving skin problems caused by cortisol imbalance. The circium japonicum extract can improve skin problems caused by excessive transformation of cortisol and increase the expression quantity of dermal collagen, skin barrier related protein and skin basement membrane related protein, so that the problems of skin barrier damage, skin sensitivity, wrinkle generation, skin elasticity reduction and the like caused by emotional pressure are effectively relieved.

The invention discloses a beauty mirror system based on multi-mode programmable light energy and a working method thereof, and belongs to the technical field of intelligent beauty instruments. According to the system, the beauty mirror is innovatively used as an intelligent control center and is connected with a detachable light energy output module through a magnetic attraction modular interface. The system is characterized in that multiple light energy output schemes for different skin care scenes are pre-stored in the system, after a user selects the schemes, a core control unit drives a light energy output module to generate a composite light energy beam subjected to strict time sequence and intensity modulation, and the light energy beam is shaped through a special optical assembly to enhance the skin tissue penetrability of the light energy beam. Therefore, a multi-dimensional beautifying effect from surface nursing to deep repairing is realized. By means of collaborative design of software and hardware, the problems that existing equipment is single in function, insufficient in targeting and poor in user compliance are solved, and the device is particularly suitable for fading deep skin problems such as nasolabial folds and striae gravidarum.

The present invention relates to a smart diaper having an improved structure, which minimizes skin problems of a wearer, increases an electrical connection force with a detection line of the diaper when a sensing device is mounted on the diaper, and minimizes a foreign body sensation or discomfort of the wearer when the sensing device is mounted on the diaper.

The invention relates to the technical field of skin care, and discloses a sustained-release composition containing azelaic acid composite lipidosome and application of the sustained-release composition in acne treatment and skin repair. Comprising a composite liposome, an encapsulated active component and a dispersion medium, the composite liposome is composed of a lipid bilayer, the lipid bilayer comprises phospholipid, cholesterol and pegylated phospholipid, and the phospholipid is a mixture of hydrogenated soybean phospholipid and dipalmitoyl phosphatidylcholine; the encapsulated active component comprises a fat-soluble component and a water-soluble component; the water-soluble components comprise a hamamelis virginiana leaf water extract and a herba portulacae extract; the dispersion medium is a phosphate buffer solution; by optimizing lipid composition, introducing surface modification and constructing a multi-layer release system, the invention aims to synergistically exert multiple effects of antibiosis, anti-inflammation, cutin regulation, red fading, repair and the like, and provides an efficient, mild and integrated solution for acne and sequelae skin problems thereof.

The present disclosure relates to the treatment of a skin condition in a subject, including but not limited to one or more of luminosity, brightness, skin pore size, skin pore count, sebum production, sebum composition, overall skin quality, eyelid laxity, fine lines under the eye, fine lines on the face, laxity on the face, perioral rhytids, moderate to severe facial folds and wrinkles such as nasolabial folds, moderate to severe facial wrinkles such as smile lines or marionette lines, age-related midface contour deficiencies, dorsal hand to correct volume deficit, glabellar lines, correction of facila depressions, either due to injury or age-related, perioral wrinkles, lip commissures, crow's feet, facial rhytides, and forehead wrinkles, comprising applying to the skin of the subject a first composition derived from one or more sponges, and a second composition comprising one or more botulinum toxins. Also provided are compositions for use in the treatment of a skin condition in a subject, including but not limited to hyperhidrosis, comprising a first composition and a second composition, wherein (a) the first composition comprises Spongilla; and (b) the second composition comprises one or more botulinum toxins. Also provided are kits, including kits for the treatment of a skin condition in a subject including but not limited to hyperhidrosis, comprising a first composition and a second composition, wherein the first composition comprises Spongilla, and the second composition comprises one or more botulinum toxins.

The invention relates to the field of cosmetics, in particular to a composition and application thereof in sunscreen. The composition adopts pure natural components, is mild and safe, and is friendly to the environment and human bodies. The dosage of a chemical sun-screening agent in a high-power sun-screening product can be reduced, and a fresh and light skin feeling is provided. The sunscreen composition focuses on full-band strong adsorption of spectral ultraviolet rays and blue rays in the early stage, the SPF value can be directly increased by 20%-35% after entering the formula, the sunscreen synergistic effect is remarkable, and the dosage of a chemical sunscreen agent can be reduced by 10%-15% or the SPF value can be increased by 20%-35% by adding 1% of the sunscreen composition. Soothing, repairing and anti-blackening effects are provided for skin problems caused by ultraviolet rays, and full-dimensional sunscreen is achieved.

This invention relates to the field of natural language processing, and in particular provides a method and system for quantifying skincare efficacy vectors by integrating multidimensional constraints and semantic intent. The method includes receiving four-dimensional heterogeneous semantic input from users; constructing a multidimensional knowledge base, which includes a semantic weight association library, an intent-vector mapping library, and a constraint-correction matrix library; calculating a dynamic priority scalar for each skin problem by combining the influence of skincare motivation and skincare goals on various major skin problems; calling the intent-vector mapping library to obtain the primitive efficacy vectors corresponding to each skin problem, weighting the primitive efficacy vectors using the dynamic priority scalar, and aggregating them using a max-pooling algorithm to generate a baseline demand vector; calling the constraint-correction matrix library to obtain the corresponding correction matrix according to the constraints, performing nonlinear correction processing on the baseline demand vector, and outputting the final target efficacy representation vector. This invention achieves accurate, safe, and personalized quantification of skincare efficacy.

A topical cutaneous composition remarkably reduced eczema, psoriasis, and other skin problems in human patients. The topical cutaneous composition is formulated using natural and toxicologically harmless components as a skin cream with an acidic or a caustic property. When the topical cutaneous composition is applied to the afflisted area, the topical cutaneous composition attacks, sooths, and cures damaged skin.

The utility model discloses comfortable and breathable pull-ups. The pull-ups comprise a main body, a belly part and a waist part, the front end of the main body is connected with an abdomen, the rear end of the main body is connected with a waist, side edges are arranged on two sides of the main body, and the main body comprises an inner layer, an absorption layer and an outer layer; wherein the inner layer and the outer layer are both provided with first net-shaped air holes, the side edges are provided with second round-hole-shaped air holes, and the belly part and the waist part are both provided with third rectangular air holes. The device is simple in structure and convenient to use, and through the arrangement of the first air holes, the second air holes and the third air holes, when the device is worn, the device has wearing portability and high absorptivity, meanwhile, the stuffiness feeling during wearing is effectively improved, the skin problem is reduced, and the device has high comfort.

The invention relates to the technical field of medicinal liquor, in particular to medicinal liquor and a preparation method thereof.The preparation method comprises the steps that main medicinal liquor raw materials are crushed, and medicinal powder is obtained; pouring the medicinal powder into Baijiu for mixed extraction, filtering after extraction, heating and concentrating, and cooling to obtain main medicinal liquor; preparing auxiliary medicinal liquor; and adding the auxiliary medicinal liquor into the main medicinal liquor to obtain the medicinal liquor. The premna microphylla is used as a main raw material and has the effects of diminishing inflammation, sterilizing, relieving pain, promoting blood circulation to remove blood stasis, removing necrotic tissue and promoting granulation, and the honeysuckle, the dandelion, the ganoderma lucidum and the like are used as auxiliary materials, so that the prepared main medicinal liquor is relatively good in overall functionality; in order to meet the treatment requirements of different kinds of diseases, different kinds of auxiliary medicinal liquor are compounded on the basis of the main medicinal liquor, part of diseases can be specifically treated, for example, gastrodia elata / polygonum multiflorum is used as an auxiliary material, and the obtained medicinal liquor has excellent performance in the aspect of treating arthralgia; corn cervi pantotrichum / ginseng / American ginseng are used as auxiliary materials, and the obtained medicinal liquor can better improve acne skin problems.

The utility model discloses a continuous suction device in the technical field of suction devices for dysphagia, which is characterized in that an elastic band is fixedly connected to a silica gel protection plate, a silica gel sleeve is integrally formed on the side wall of the silica gel protection plate, a hollow suction end is integrally formed on the silica gel sleeve, a limiting groove is formed between the silica gel sleeve and the suction end, and the silica gel sleeve is fixedly connected with the elastic band. During use, the elastic band can be sleeved on the head of a human body, the purposes of limiting and preventing separation can be achieved, continuous suction can be achieved, the elastic band can be completely wrapped in an oral cavity, and the elastic band is convenient to fix, more sterile and capable of preventing cross infection. Skin problems caused by saliva outflow of patients with dysphagia and aspiration caused by incapability of swallowing saliva can be prevented.

The invention belongs to the technical field of biological medicines, and particularly relates to a hyaluronic acid-oleic acid conjugate as well as a preparation method and application thereof. The hyaluronic acid-oleic acid conjugate with the structure shown in the formula I belongs to a macromolecular emulsifier, and has a lower CMC value and higher stability compared with an oleic acid or sodium oleate micromolecular emulsifier, so that the hyaluronic acid-oleic acid conjugate can entrap water-insoluble active substances. The hyaluronic acid is modified by using oleic acid, so that the permeation effect of the supramolecular self-assembled nanoparticles can be improved by virtue of the percutaneous permeation promotion effect of the oleic acid, meanwhile, skin pore blockage caused by oil-soluble raw and auxiliary materials is avoided, and the skin problems of coarse pores, blackheads and the like are reduced. Besides, the hyaluronic acid-oleic acid conjugate provided by the invention can play a role in repairing the skin by the hyaluronic acid and the oleic acid, and meanwhile, the efficacy of the oil-soluble cosmetics is further improved by virtue of the permeation enhancing effect of the oleic acid. Formula I

The utility model discloses an electrical stimulation intensity and negative pressure linkage control system and an electrical stimulation therapeutic apparatus, and relates to the field of electrode control. An electrical stimulation signal generation module, a current detection module and a control module form a closed-loop control loop for generating an electrical stimulation signal; the air pump, the air pressure detection module and the control module form a closed-loop control loop of the pressure in the suction cup of the target electrode, the control module can flexibly adjust the intensity of an electrical stimulation signal and the negative pressure condition in the suction cup of the target electrode according to treatment requirements, and therefore the skin problems caused by the fact that the negative pressure value is constant all the time are avoided. In the treatment process, the negative pressure value in the electrode suction cup can also change along with the change of the stimulation current intensity of the electrical stimulation signal under the action of the control module, the negative pressure massage effect can be achieved, the output effect that negative pressure is matched with electrical stimulation to be mutually correlated can be generated, muscle blood circulation of a rehabilitation patient can be accelerated, and the rehabilitation effect is improved. The effects of enhancing analgesia and eliminating stimulation fatigue are achieved, and the user experience is improved.

The invention discloses an anti-inflammatory external health-care liquid based on natural extracts and a preparation method of the anti-inflammatory external health-care liquid. Comprising the following components in percentage by mass: 12-18% of a honeysuckle extract, 10-14% of a liquorice extract, 8-14% of an aloe extract, 3-5% of a tea tree essential oil extract, 5-7% of a chamomile extract, 2-3% of a purslane extract, 1-3% of a seaweed extract, 3-5% of a liquorice extract, 1-5% of a pomegranate extract, 5-7% of a motherwort extract and 2-6% of an avocado extract. The skin care product is prepared from the following components in percentage by weight: 5-8% of radix sophorae flavescentis extract, 5-10% of radix notoginseng extract, 4-7% of an emulsifier, 8-14% of a humectant and the balance of deionized water, totaling 100%. Through a scientific and reasonable formula and a preparation method, the health care liquid can provide natural, safe and effective skin care effects, is suitable for various skin problems, and is especially suitable for sensitive skin.

1. The name of the design product: therapeutic instrument hand tool treatment head (intense pulsed light). 2. The use of the design product: it is an intense pulsed light output treatment terminal, used for skin problem treatment. 3. The design points of the design product: in shape. 4. The picture or photo that best indicates the design points: perspective view. 5. Other circumstances that need to be explained: the double-dot dashed line in the front view, rear view, top view, bottom view and perspective view indicates that its length is indefinite.

The invention provides a mild multi-effect anti-acne enzyme composition for teenagers and application of the mild multi-effect anti-acne enzyme composition. The composition comprises a fig extract, a roselle extract and keratinase. The composition provided by the invention is safe and non-irritant in components, the fig extract and the keratinase play a cutin renewal role of biological enzyme, and the roselle extract fundamentally promotes the generation of skin renewal related enzymes and assists in accelerating the decomposition of keratosuppository. The three components are synergistically compatible, pores are dredged, the skin problems such as teenager closed acne and blackhead are solved, and efficient and mild acne resistance is achieved.

The invention provides a phenolic amide derivative and application thereof, relates to application of a compound and a composition thereof in preparation of cosmetics or medicines for preventing, treating and relieving acne, and provides a medicine or cosmetic composition which comprises a therapeutically effective amount of compound, or at least one of a racemate, a stereoisomer, a geometric isomer, a tautomer, an isotope label, a hydrate, a solvate, a polymorphic substance, a metabolite, a prodrug and pharmaceutically acceptable salt or ester. The present invention provides the prevention, treatment or alleviation of skin problems associated with Propionibacterium acnes, including comedo, acne, folliculitis; according to the phenolic amide derivative with a novel structure, the structural type of the phenolic amide compound is enriched, the activity of inhibiting propionibacterium acnes is increased on the basis of retaining the anti-inflammatory activity of the phenolic amide compound, and the aim of treating both symptoms and root causes of skin problems related to the propionibacterium acnes is achieved.

The invention discloses an anti-aging composition containing recombinant collagen. The composition comprises the following components: (1) 2-5g of recombinant collagen; (2) 1-2 g of hyaluronic acid; (3) 0.2 to 0.5 g of a collagen degradation product; (4) 0.2 to 0.3 g of an anti-TGF (Transforming Growth Factor)-beta 1 monoclonal antibody; (5) 0.2 to 0.5 g of vitamin C; (6) 0.2 to 0.3 g of vitamin E; (7) 0.5-1 g of a green tea extract; and (8) adding the aqueous solution to 100 g. The anti-aging composition can effectively delay the skin aging process, improve the skin elasticity and reduce generation of wrinkles and fine wrinkles. The composition not only can be used in daily skin care products, but also can be used for treating skin problems caused by aging, such as skin laxity, fine wrinkles and darkness, and has a remarkable market prospect.