14 results about "Cornus officinalis fruit extract" patented technology

The invention provides a preparation method of a dogwood extract and application of the dogwood extract in bone strengthening products, and belongs to the technical field of medicine extraction. The method comprises the following steps: (1) crushing a dogwood raw material, and immediately spraying an acid solution; (2) sequentially extracting the pretreated material by adopting an ethanol water solution containing citric acid and L-ascorbic acid as a first-phase extraction solvent and a phosphate buffer solution containing a compound enzyme preparation as a second-phase extraction solvent; (3) combining the extracting solutions, sequentially separating through an ultrafiltration membrane and at least two stages of nanofiltration membranes to obtain active fractions with different molecular weight intervals, and recombining the active fractions according to a preset proportion to obtain a refined solution; and (4) drying the refined liquid to obtain the dogwood extract. The preparation method provided by the invention has the advantages of high extraction rate of target active ingredients (especially aglycone), synergistic retention of multiple active ingredients, strong process controllability, suitability for large-scale production and the like.

The invention relates to the technical field of natural product extraction, in particular to an ultrasonic-assisted extraction method of a dogwood extract containing ursolic acid. The ultrasonic-assisted extraction method comprises the following steps: step 1, cleaning dried dogwood, removing stems and leaves, drying and grinding to obtain dried dogwood powder; step 2, adding the dried dogwood fruit powder into a solvent, carrying out ultrasonic treatment, centrifuging, and taking supernate, so as to obtain a dogwood extract containing ursolic acid; the solvent comprises ethanol and water. According to the method disclosed by the invention, the extraction rate of the dogwood extract containing ursolic acid can be obviously improved, the cost is low, large-scale application in the industry is facilitated, and important technical support and theoretical basis are provided for high-value development and utilization of dogwood resources.

The application belongs to the technical field of cosmetic production and discloses a composition for improving skin transparency, which comprises a main extract and an auxiliary extract, the main extract is a mixture of citrus peel extract and cornus officinalis extract, the auxiliary extract is selected from reed extract and / or liquorice extract, the mass ratio of the citrus peel extract and the cornus officinalis extract in the main extract is 3-5:5-8, and the mass ratio of the main extract and the auxiliary extract is 8-13:5-8. The composition provided by the application can significantly inhibit tyrosinase through the synergistic effect of multiple action pathways, thereby realizing the whitening effect. In addition, it is found through tests that the composition has good skin color lightening capacity. In addition, the application also discloses application of the composition for improving skin transparency and a cosmetic.

The invention relates to the technical field of foods, in particular to a dogwood extract and a preparation method and application of a dogwood pet food capable of nourishing nerves. The extract is prepared by any one of the following schemes: crushing dried cornus officinalis kernels or whole cornus officinalis fruits, and performing reflux extraction with a 70% ethanol solution at 80 DEG C for 3 times, 2 hours each time; combining the extracting solutions, concentrating under reduced pressure, and freeze-drying to obtain a dogwood extract; the method comprises the following steps: crushing dried cornus officinalis kernels or whole cornus officinalis fruits, and freeze-drying the crushed cornus officinalis kernels or whole cornus officinalis fruits in a nitrogen atmosphere by using a freeze dryer to obtain the cornus officinalis extract. The raw material is used as one of the main components as a pet food raw material.

This invention provides a moisturizing, repairing, and anti-allergic composition containing Cornus officinalis extract and its application, relating to the field of cosmetic technology. The composition comprises the following ingredients: Cornus officinalis extract, beetroot extract, *Prickly pear* fruit extract, *Chrysanthemum indicum* extract, and carboxymethyl deacetylated chitosan. This invention overcomes the limitations of traditional repair products that rely on only a single ingredient. Through a synergistic five-component system of Cornus officinalis extract, carboxymethyl deacetylated chitosan, beetroot extract, *Prickly pear* fruit extract, and *Chrysanthemum indicum* extract, it simultaneously achieves moisturizing, water-locking, barrier repair, and soothing and anti-allergic effects, and is suitable for various sensitive skin types, being gentle and safe.

The invention provides a plant extraction gel for improving vaginal elasticity and a preparation method and application thereof, and belongs to the technical field of biological medicine. The plant extraction gel is prepared from fructus evodiae extract, Chinese herbaceous peony root extract, rhodomyrtus tomentosa fruit extract, dogwood extract, lime peel extract, cyrtomium rhizome extract, zedoary turmeric oil, melaleuca alternifolia oil, rosemary leaf oil, matrine and auxiliary materials. According to the invention, the fructus evodiae extract increases the thickness, the wettability and the elasticity of a vaginal wall by simulating an estrogen function; the Chinese herbaceous peony root extract has anti-inflammatory and anti-oxidation effects. The rhodomyrtus tomentosa fruit extract can tighten tissues in time, the dogwood extract can improve microcirculation and provide nutrition, and the lime peel extract can protect the elastic fibers from oxidative damage. All the components in the plant extraction gel supplement each other, and the comprehensive effect of recovering and maintaining vagina elasticity is achieved together. The plant extract gel disclosed by the invention has obvious effects in balancing vaginal flora and improving vaginal elasticity.

The invention belongs to the technical field of livestock and poultry feed additives, and particularly relates to application of a dogwood extract in preparation of a compound feed for relieving diarrhea and enteritis, and the dogwood extract is an aqueous extract of a dogwood medicinal material. 500mg-2000mg of the dogwood extract is added into each kilogram of the basal feed, so that the compound feed is obtained. The compound feed can relieve diarrhea and intestinal inflammation of weaned piglets, especially at the 21-35-day-old stage, the diarrhea occurrence rate of the weaned piglets can be remarkably reduced by 15% or above, meanwhile, the average daily gain is increased, the feed-gain ratio is reduced, the comprehensive growth performance is better than that of a control group, the level of pro-inflammatory cytokines in IPEC-J2 cells or intestinal mucosa tissues is remarkably reduced, and the weaned piglets are prevented from suffering from diarrhea and intestinal inflammation. Meanwhile, the level of anti-inflammatory cytokines is up-regulated, and excessive activation of an NF-kB key inflammatory signal channel can be inhibited.

The invention belongs to the technical field of medicinal and edible functional foods, and particularly relates to a high-activity tablet candy containing a dogwood extract and a preparation method of the high-activity tablet candy. The preparation method comprises the following steps: by taking dried cornus officinalis pulp as a main raw material, efficiently enriching iridoid glycoside (loganin and morroniside), polysaccharide and total phenolic acid active ingredients by virtue of an ultrasonic-microwave synergistic extraction and composite enzymolysis coupling process, then optimizing a formula by virtue of functional auxiliary materials, granulating and tabletting. The total amount of loganin and morroniside in the product is larger than or equal to 5%, the total polysaccharide is larger than or equal to 8%, the total phenolic acid is larger than or equal to 3%, the product has the effects of enhancing immunity, resisting oxidation and assisting in bacteriostasis, is moderate in sour and sweet taste and convenient to take, and solves the problems that a traditional dogwood product is low in active ingredient utilization rate, gastrointestinal irritation risks exist, and the dosage form is single. The preparation process is green and efficient, the extraction time is shortened by 40% or above, the yield of the active ingredients is increased by 30%-50% compared with a traditional method, and the method is suitable for industrial production.

The application relates to the cosmetic technical field, and particularly discloses a multi-channel whitening and freckle-removing compound and a preparation method thereof. In the multi-channel whitening and freckle-removing compound, the preparation raw materials comprise emollients, moisturizers, skin protectants A, antioxidants, skin protectants B, skin protectants C, a whitening composition, a composite extract and a solvent; the whitening composition comprises niacinamide; the skin protectants C comprise a phenylethyl resorcinol inclusion compound; and the composite extract comprises grape fruit cell extract and cornus officinalis extract. The multi-channel whitening and freckle-removing compound is prepared by compounding multiple functional components, synergistically acts from multiple mechanisms such as inhibiting melanin synthesis, blocking melanin transport, antioxidation and repairing skin barrier, and can realize the high-efficiency whitening and freckle-removing effect while guaranteeing the skin safety.

The invention discloses a preparation method of an artemisia apiacea fermentation extract and dogwood extract composition and application of the artemisia apiacea fermentation extract and dogwood extract composition in acne treatment medicines and cosmetics, belongs to the technical field of traditional Chinese medicine and microorganism crossing, and relates to the preparation method and application of the artemisia apiacea fermentation extract and dogwood extract composition. The preparation method comprises the following steps of: 1, obtaining a lactobacillus casei paracasei enlarged culture solution and a phytobacterium plantarum enlarged culture solution; 2, obtaining double-bacterium fermented artemisia apiacea extract powder; 3, obtaining freeze-dried powder of the double-bacterium fermented artemisia apiacea extract; 4, obtaining dogwood extract freeze-dried powder; and 5, mixing the double-bacterium fermented artemisia apiacea extract freeze-dried powder with the dogwood extract freeze-dried powder to obtain the product. The artemisia apiacea fermentation extract is used as an active ingredient in the medicine and cosmetics for treating acne. The invention provides the application of the double-bacterium fermentation artemisia apiacea extract in intervention of acne caused by propionibacterium acnes for the first time, and the double-bacterium fermentation artemisia apiacea extract is strong in antibacterial and anti-inflammatory activity, high in safety and not easy to generate drug resistance.

The invention discloses a composition with a permeation promoting effect as well as a preparation method and application thereof, and relates to the technical field of cosmetics. The composition disclosed by the invention is obtained by fermenting a fermentation substrate by thalli; the fermentation substrate is prepared from the following raw materials: a dogwood extract, creatinine and polyhydric alcohols. The composition provided by the invention has an excellent penetration promoting effect, can promote the absorption of active ingredients by skin, is free of irritation to skin temperature, is suitable for being used as a penetration promoting agent for preparing cosmetics, and improves the utilization rate of the active ingredients of the cosmetics.

The application discloses application of a dendrobium extract in preparation of a medicine for treating type 2 diabetes, and mainly relates to the technical field of dendrobium. Specifically, the application provides a medicine for treating type 2 diabetes and containing the dendrobium extract, improves stability of components in the medicine for treating type 2 diabetes in an acid, neutral or alkaline environment, and slows down blood sugar increase. Compared with the prior art, the medicine for treating type 2 diabetes prepared by the application takes the dendrobium extract as a core, is matched with a synergistic emulsion, a rhizoma polygonati extract, a fructus corni extract, a salvia miltiorrhiza extract, a momordica charantia extract, vitamin B and trace elements of chromium, and through cooperation with traditional Chinese medicine components, can synergistically regulate blood sugar metabolism, enhance insulin sensitivity and improve microcirculation, can stabilize blood sugar, improve insulin resistance and lipid metabolism, improve immunity and cardiovascular function, and provides a safe and effective medicine for prevention and treatment of type 2 diabetes.

The invention discloses composite powder for controlling blood sugar as well as a preparation method and application of the composite powder. The composite powder comprises the following components in parts by weight: 15-30 parts of a dogwood extract-Chinese yam-sweet almond-hawthorn-medlar freeze-dried material and 30-45 parts of a dogwood residue-phaseolus calcaratus-white hyacinth bean zymolyte, and is prepared by compounding the two components and performing superfine grinding. According to the invention, firstly, core components for regulating and controlling blood sugar in dogwood are enriched through a step-by-step extraction method, then the sugar control effect is further enhanced through a medicinal and edible combination scheme and a freeze-drying process, and finally, dogwood residues, phaseolus calcaratus and white hyacinth beans are treated through a biological enzymolysis technology. And compounding the obtained freeze-dried product and the enzymolysis product, and performing superfine grinding to form the composite powder capable of efficiently controlling the blood sugar. The dogwood is subjected to step-by-step extraction and biological enzymolysis treatment, active ingredients contained in the dogwood are reserved to the maximum extent, and meanwhile the dogwood extracting agent has the advantages of being scientific in ingredient, stable in effect, high in synergism and the like.

This invention provides the application of caffeine-kaempferol cocrystal in the preparation of anti-hair loss and hair growth products, a scalp care solution, and its preparation method, relating to the field of cosmetic technology. The scalp care solution comprises: 0.5%-2% Cornus officinalis fruit extract, 0.1%-2% caffeine-kaempferol cocrystal, 0.01%-0.5% recombinant type XVII human collagen, 0.1%-0.2% allantoin, 0.01%-0.2% sodium hyaluronate, 5%-15% glycerin, 6%-10% 1,3-propanediol, 35%-40% ionic liquid, 0.02%-0.2% sodium EDTA, 0.5% phenoxyethanol, 0.1% ethylhexylglycerin, and the balance being water. This scalp care solution uses ionic liquid and caffeine-kaempferol cocrystal as penetration-enhancing components; the combination of ionic liquid and ionic liquid in anti-hair loss and hair growth products can effectively improve their hair growth efficacy.