The invention relates to the medicines for gynecopathy, in particular to physiological balance liquid for adjusting microecology in vaginas of women, solving the problem that the traditional gynecological lotion kills probiotics while killing pathogens, thus causing vaginal flora imbalance and low immunity and further causing repeated vaginitis. The physiological balance liquid is formed by major materials, auxiliary materials and water, wherein the major materials include the following components according to mass concentration: 0.7-1% of sodium chloride, 0.01-0.04% of potassium chloride, 0.01-0.04% of calcium chloride, 0.01-0.04% of magnesium sulfate, 0.001-0.01% of manganese sulfate and 0.01-0.05% of glucose; and the auxiliary materials include the following components according to mass concentration: 0.1-1% of soy peptide, 0.001-0.01% of isoflavone, 0.05-0.6% of tea tree oil and 0.002-0.04% of carotene. The physiological balance liquid conforms to physiological conditions of the vagina mucosa, increases the absolute number of the lactobacillus, a predominant bacterium, reduces the pathogens, maintains the balance of microecology in vaginas and improves vaginal cleanliness and the immunity of the vagina mucosa, thus achieving the aims of preventing gynecological vagina inflammation and reducing the reoccurrence rate of gynecological vaginitis. The physiological balance liquid has good biocompatibility and no irritation or side effects and is safe.