31 results about "Lactobacillus jensenii" patented technology

Use of an association of lactobacilli for preparation of a pharmaceutical composition for treatment of vaginosis and vaginitis. Said bacteria association comprises the Lactobacillus brevis and Lactobacillus salivarius subs. salicinius species, possibly in combination with one or more species selected from Lactobacillus salivarius subs. salivarius, Lactobacillus jensenii, Lactobacillus catenaforme, Lactobacillus minutus and Lactobacillus gasseri.A pharmaceutical composition comprising said association of lactobacilli adapted for treatment of vaginosis and vaginitis.A method of treating vaginosis and vaginitis based on administration of said pharmaceutical composition.

The invention discloses lactobacillus jensenii and application thereof. The lactobacillus jensenii is particularly lactobacillus jensenii IMJ-1, and the file No. of the lactobacillus jensenii IMJ-1 in the General Microbiological Culture Collection Center of China Microbial Culture Collection Management Committee is CGMCC No. 6558. The lactobacillus jensenii IMJ-1 CGMCC No.6558 has high H2O2 generation capability, can effectively suppress breeding of external pathogenic bacteria and other conditional pathogenic bacteria, and has a high binding function to epithelial cells of vagina, and accordingly, breeding of bacteria strains on the vaginal epithelium is guranteed. Besides, the lactobacillus jensenii IMJ-1 CGMCC No. 6558 has a certain application prospect in preventing and curing bacterial vaginosis.

The invention relates to the technical field of food, in particular to a mouth odor refreshing solid drink containing dendrobium officinale prebiotics and probiotics. Dendrobium officinale mannooligosaccharide is added as the prebiotic component, lactobacillus acidophilus, lactobacillus casei, lactobacillus jensenii, lactobacillus Raman, bifidobacterium longum, bifidobacterium breve, bifidobacterium ovale, bifidobacterium thermophilum, lactobacillus rhamnosus, streptococcus thermophilus and yeast are added for compounding to serve as the probiotic component, and then a compound vitamin component is added. The dendrobium officinale mannooligosaccharide and compound vitamin can promote the proliferation of compound probiotic components, rapidly change the structure of oral and intestinal flora, help repair buccal inflammation and damaged gastrointestinal mucosa, regulate the normal functions of the oral cavity, teeth and gastrointestinal tract, solve the causes of halitosis originated from oral factors and halitosis originated from non-oral factors, and can achieve the effect of mouth odor refreshing from the origin. The solid drink can be applied to in toothpaste, mouthwash, functional beverages and other products.

The invention discloses a lactobacillus jensenii and application thereof. The lactobacillus jensenii disclosed by the invention is named as IMJ-19, and is collected in the China General Microbiological Culture Collection Center on July 14th, 2014, with the collection number of CGMCC No.9439. The lactobacillus jensenii IMJ-19 has strong capability of generating H2O2, can effectively inhibit the growth of foreign pathogenic bacteria and other conditioned pathogens, also has strong adhesion action to vagina epithelial cells, and ensures the colonization of strains on vaginal epithelial, and the lactobacillus jensenii IMJ-19 has certain application prospects on the aspect of prevention and treatment of urogenital tract infection.

The invention provides lactobacillus jensenii and application thereof for preparing vaginal bacteriostatic drugs. The lactobacillus jensenii is deposited in the China General Microorganisms CollectionCenter of China Committee for Culture Collection of Microorganisms, and the preservation number is CGMCC No. 14112. Research on the metabolic performance of the lactobacillus jensenii provided by theinvention discovers that, compared to ordinary lactobacillus jensenii, the strain has high lactic acid production capacity, high hydrogen peroxide production capacity, high bacteriostatic ability topathogenic bacteria, and outstanding vaginal epithelial cell adhesion ability. Based on the new properties discovered above, the invention determines a new use of the lactobacillus jensenii for preparing the vaginal bacteriostatic drugs, and the vaginal bacteriostatic drugs can realize treatment of a variety of bacterial vaginal diseases. The bactericidal agent provided by the invention has obvious effects on bacterial vaginal diseases, is safe and non-toxic, has good stability, and can be stored for a long time. The invention also relates to the use of the lactobacillus jensenii in drugs forprevention and/or treatment of gynecological diseases.

The invention discloses active bio-enzyme conditioning extract. The active bio-enzyme conditioning extract comprises, by mass, 14%-16% of lactobacillus acidophilus, 1.35%-15.5% of bifidobacterium longum, 12.5%-14.5% of lactobacillus casei, 11.8%-13.8% of oviform bifidobacteria, 11%-13% of lactobacillus jensenii, 8%-10% of Raman lactobacillus, 6.5%-8.5% of bifidobacterium thermophilum, 1.5%-2.5% of pullulan, 1.5%-2.5% of bacillus subtilis fibrinolytic enzyme, 1.5%-2.5% of lysozyme, 1.5%-2.5% of lysozyme beta-glucan, 1.5%-2.5% of plankton extract, 1.3%-1.7% of bletilla striata root extract, 0.8%-1.2% of scutellaria baicalensis extract, 1%-1.4% of centella asiatica extract, 0.4%-0.6% of licorice extract, 0.7%-0.9% of polygonum cuspidatum extract and 0.3%-0.5% of matricaria extract. The active bio-enzyme conditioning extract is an active bio-enzyme and plant ferment formula developed specially for people with acne-prone and sensitive skin, and is capable of fundamentally improving sensitive, dark and rough skin, removing acne, and recovering white and bright skin.

The invention provides a primer probe combination for detecting female vaginal microorganisms based on quadruple droplet digital PCR and application of the primer probe combination. The primer probe combination comprises a primer pair and a probe, wherein the primer pair and the probe are used for amplifying and detecting a polE gene of inert lactobacillus, a galR gene of lactobacillus jensenii, aCbiQ1 gene of lactobacillus crispatus and a murQ gene of lactobacillus gasseri, wherein the primer pair has relatively high specificity, can avoid primer amplification of other strains during amplification, is used in combination with quadruple droplet digital PCR, classifies and quantitatively analyzes droplets after PCR amplification, and can determine the concentration of each lactobacillus ina sample, determine the dominant microorganisms of the female vagina and realize vagina microorganism typing.

The invention discloses a probiotics syrup capable of improving immunity. Lactobacillus acidophilus, lactobacillus casei, lactobacillus jensenii, lactobacillus plantarum, bifidobacterium longum, bifidobacterium breve, oval bifidobacterium, bifidobacterium bifidum, bifidobacterium catenulatum, bifidobacterium, bacillus acidi lactici, bacterium lacticum, lactic acid bacteria, filiform saccharomycetes, actinomycetes, bifidobacterium thermophilum, gram-positive cocci, streptococcus, galactococcus, intermediary streptococcus, acetobacter aceti, protease, lipase, amylase, cellulose, hemicellulase, pectinase and xylanase are adopted and mixed with traditional Chinese medicine extracts to prepare the probiotics syrup capable of improving immunity. The prepared probiotics syrup can resist pathogenic bacteria, is helpful for cancer treatment and prevention, and can suppress tumor growth and allergic diseases, reduce serum cholesterol and prevent osteoporosis. The probiotics syrup has the advantages of being capable of becoming effective quickly, obvious in effect, high in safety and the like.

The invention discloses a composition composed of three kinds of lactobacillus. The composition contains a lactobacillus rhamnosus strain, a lactobacillus gasseri strain and a lactobacillus jensenii strain, and can resist bacterial vaginosis and related vaginal infection. The composition has a remarkable effect on the bacterial vaginosis and related vaginal diseases, is safe and non-toxic, has good stability, and can be stored for a long time. Compared with other commercially available preparations at present, the strains in the composition can be effectively planted, and the three kinds of lactobacillus strains can play a synergistic role; and compared with a single strain preparation, the composition composed of the three kinds of lactobacillus has the advantage that vaginal microecologycan be formed more obviously.

The invention discloses a preparation for preventing and controlling bee fungal diseases. The preparation consists of 0.1 to 2 percent of (E)-N-(6,6-dimethyl heptanoic-2-olefin-4-alkynyl)-N-methyl-1-naphthalene methylamine hydrochloride, 0.1 to 4 percent of beneficial microorganism and 94 to 99.8 percent of soluble starch or saccharides. The beneficial microorganism comprises one or random combination of bacillus subtilis, bacillus licheniformis, bee bifidobacterium, bifidobacterium asteroids, minimum bifidobacterium, bifidobacterium coryneforme, lactobacillus jensenii, lactobacillus amylovorus, lactobacillus plantarum, tiny lactobacillus and lactobacillus bifermentans; and a gram of the beneficial microorganism comprises 10<9> to 5*10<9> viable bacteria. The preparation for preventing and controlling bee fungal diseases is applied to prevention and control of bee or silkworm fungal diseases.

The invention provides a composite probiotic preparation for targeting treatment on tumor and a preparation method of the composite probiotic preparation. By adopting the technical scheme, on the basis of physiological actions of various probiotics and synergic relationships of the probiotics, bifidobacterium adolescentis, lactobacillus crispatus, lactobacillus jensenii, lactobacillus vaginalis and lactobacillus johnsonii are adopted as preparation main bodies, on the basis, a compounding scheme is designed from angles of amount proportioning, numbers of viable organisms, and the like, and aneffective preparation method is provided. By adopting the preparation, targeting treatment on tumor can be achieved in an oral taking mode, and meanwhile the preparation can have synergetic effects with other anti-tumor medicines to promote anti-tumor effects of the preparation. The preparation is safe and non-toxic, free of conspicuous side effect, free of limits of tumor sizes and types, and good in quantitative treatment effect on various types of tumor.

The invention relates to actobacillus jensenii and application thereof and particularly relates to Lactobacillus jensenii IMJ-118 for preventing and treating bacterial vaginosis. The strain has relatively strong capability of producing H2O2, and can effectively inhibit the growth of external pathogens and other conditional pathogenic bacteria; and meanwhile, the strain has a relatively strong adhesive effect against vaginal epithelial cells and ensures the colonization on vaginal epithelium. Thus, the Lactobacillus jensenii IMJ-118 provided by the invention has certain application prospects in the aspect of preventing and treating bacterial vaginosis.

The invention provides a probiotic preparation for repairing and maintaining microecological balance of the vagina. The probiotic preparation is probiotic powder, and the probiotic powder is composed of lactobacillus plantarum, lactobacillus rhamnosus, lactobacillus acidophilus, lactobacillus jensenii and lactobacillus gasseri. The probiotic preparation provided by the invention has the effects of resisting to bacteria, diminishing inflammation, removing swelling, easing pain, inhibiting bacteria and relieving itching, meanwhile, has the functions of refreshing and removing odor, and can effectively relieve discomfort caused by female vaginitis; meanwhile, the probiotic preparation provided by the invention can also prevent gynecological inflammation, the cervical cancer caused by HIV or HPV and other diseases; and the probiotic preparation provided by the invention is not added with any chemical additive, is natural and healthy, and has no side effect.

The invention relates to a culture medium for culturing a living biological medicine and application of the culture medium. The culture medium for culturing the living biological medicine is prepared from peptone, beef extract, lactulose, mannose oligomer, raffinose, yeast extract, diammonium hydrogen citrate, K2HPO4, MgSO4, MnSO4, Tween-80 and L-cysteine. The living biological medicine comprises any one or a combination of at least two of lactobacillus reuteri, lactobacillus paracasei, lactobacillus acidophilus, lactobacillus rhamnosus, bifidobacterium longum, pediococcus pentosaceus, lactobacillus crispatus, lactobacillus jensenii or lactobacillus gasseri. The culture medium has an unexpected promoting effect on growth, proliferation, metabolism and efficacy exertion of living biological medicines. The efficacy is such as prevention or treatment of gastrointestinal diseases, immune diseases, cancers, vaginitis and other diseases.

Symbiotic bacteria generally mainly producing Lactobacillus bacteria producing H2O2 are distributed on vaginal mucosa of a healthy woman of childbearing age, and the Lactobacillus bacteria functions in protectively preventing urinary and reproductive system infections. Multiple Lactobacillus bacteria are already provided with resistance to, for example, HIV virus by bioengineering so as to prevent the urinary and reproductive system infections. Lactobacillus jensenii producing H2O2, a principle member in the vaginal microbial flora, is reconstructed by bioengineering, so that the Lactobacillus jensenii is enabled to produce and secrete a powerful broad-spectrum antiviral molecule, human IFN Alpha-2b.

The invention relates to poplar cutting nutritional soil. The poplar cutting nutritional soil comprises, by weight, field soil, compound fertilizers, zeolite, activated carbon, soybeans, egg white, lactobacillus jensenii solution, saccharomyces cerevisiae solution, radix codonopsis, radix astragali, fructus lycii, lemons, honey, vitamin C, taurine, calcium magnesium phosphate fertilizers, ammonium superphosphate, aspartic acid, glutamic acid and water. The poplar cutting nutritional soil has the advantages that the water retention and fertilizer conservation capacity of the field soil, the activated carbon and the zeolite is utilized, the field soil, components of the poplar cutting nutritional soil are arranged in a layered manner, and accordingly nutrient sustained-release effects can be realized; nutrition can be assuredly directly supplied to roots in integral cutting rooting procedures, accordingly, the survival rate of cutting can be greatly increased, obvious effects can be realized, the survival rate can be increased from the conventional survival rate of 67.6% and is higher than 82.4% at least as proved by experiments, and the poplar cutting nutritional soil is worthy of being popularized and utilized.