89 results about "Hemolytic streptococcus" patented technology

A reagent is provided for the detection of an exotoxin protein produced by a betahemolytic streptococcus bacteria suspected of being present in a host biological fluid collected from a subject. A kit is provided that is readily usable by an unskilled user and merely requires that an element of the kit be contacted with a biological sample and that element is then subjected to electromagnetic spectral energy. The incident electromagnetic spectral energy then reacts with the exotoxin protein indicator and can be reliably measured by an electromagnetic spectral emission. The emission is measured by a reporting module and is displayed to the user in a form recognized by the user's sensory systems; sight, sound, etc. or a combination thereof.

The invention provides an oral composition which is an oral preparation prepared by taking Periplaneta americana extract and Punicosides as active ingredients, wherein the weight ratio of the Periplaneta americana extract to Punicosides is 1:1-1:5. The invention also provides a preparation method and application of the oral composition. According to the oral composition disclosed by the invention, toothpaste can perform synchronous nursing on the oral cavity, teeth and gingiva and can effectively solve dental ulcer, the Punicosides have high in-vivo anti-oxidation and free radical cleaning activities, and the oral composition has a broad-spectrum antibacterial effect, has obvious effects of inhibiting staphylococcus aureus, hemolytic streptococcus, comma bacillus and shigella dysenteriae and has the effects of astringing, stopping bleeding, improving eyesight and the like.

A reagent is provided for the detection of an exotoxin protein produced by a beta-hemolytic streptococcus bacteria suspected of being present in a host biological fluid collected from a subject. An enzyme inhibitor is present to inhibit rogue protein modification of the substrate to prevent a false positive result of the color change. A kit is provided that is readily usable by an untrained user and merely requires that an element of the kit be contacted with a biological sample and thereafter no further actions are required by the user before a discernable color change is observed with visible or UV light and a positive/negative results reference card.

The present invention discloses a grass carp enteritis treatment drug composition, which contains, by weight, 10-30 parts of humulus scandens, 20-30 parts of humifuse euphorbia herb, 2-10 parts of melia azedarach leaf, 20-25 parts of heartleaf houttuynia herb, 2-10 parts of arborvitae leaf, and 2-7 parts of garlic. The invention further discloses a preparation method for the drug composition. According to the grass carp enteritis treatment drug composition, honeysuckle provides an anti-pathogenic microorganism effect, a certain inhibition effect is provided for a variety of pathogenic bacteria such as staphylococcus aureus, hemolytic streptococcus, escherichia coli, shigella dysenteriae, vibrio cholerae, typhoid bacillus, paratyphoid bacillus and the like, and a certain inhibition effect is further provided for pneumococcus, meningococcus, pseudomonas aeruginosa, and tubercle bacillus. The preparation method is simple and easy to perform, and is suitable for mass production.

The invention relates to a lignin compound that could prevent yellow staphylococcal bacteria and B type hemolytic streptococcus, and the medicine combination of the compound. The invention of lignin Morgan dandehon herb acid A and Rufescidride has obviously effect restraining yellow staphylococcal and B type hemolytic streptococcus. It is also respected to prevent the diseases caused by them, like boil, blain, toxicity epidermis necrolysis, pneumonia, etc.

The invention provides application of a medicine containing catechin shown in formula (I) or catechin polymorphs to preparation of antibacterial medicines. Through experiment research, the catechin is wide in antibacterial spectrum and has exact inhibiting effect on various pathogenic microorganisms such as staphylococcus aureus, escherichia coli, candida albicans, pseudomonas aeruginosa and hemolytic streptococcus; meanwhile, the catechin has good selectivity and has no irritation to normal flora and vagina mucosa, thereby being promising in application prospect on preparation of the antibacterial medicines. Formula (I).

The invention discloses a natural sea salt nasal irrigation agent which is prepared through normal-temperature dissolution with purified water and glycerinum as solvent, natural sea salt as solute and domiphen bromide as pathogenic bacteria inhibitor. Every 100 L of nasal irrigation agent contains 0.85-0.95 kg of natural sea salt, 0.5-1.5 L of glycerinum and 0.01-0.05 kg of domiphen bromide. The natural sea salt nasal irrigation agent has the sodium chloride content of 0.85-0.95% (mg/ml), the total heavy metal quantity smaller than or equal to 2 micrograms per milliliter (according to Pb), the pH value of 5.0-7.0 and the cytotoxicity not larger than the second level, causes no sensitization response or vaginal stimulation reaction, has the total bacterial colony number smaller than or equal to 100 cfu/ml and the total fungal colony number smaller than or equal to 100 cfu/ml, can not detect coliform, pseudomonas aeruginosa, staphylococcus aureus and hemolytic streptococcus, can be used for acute and chronic rhinitis, allergic rhinitis, seasonal rhinitis, exercise-induced rhinitis, atrophic rhinitis, nasal polyp, nasal obstruction caused by cold and the like, epistaxis caused by after-nasal-surgery cleaning and dry climatic nasal blood capillary rupture, and the like.

The invention belongs to the field of medicine and personal care, and particularly relates to propolis-aloe bacteriostatic gel and a preparation method thereof. The propolis-aloe bacteriostatic gel isprepared from the following raw materials in percentage by mass: 8-12% of golden cypress, 8-10% of fructus cnidii, 6-11% of stemona, 9-12% of fructus kochiae, 7-9% of divaricate saposhnikovia roots,4-8% of seaweeds, 3-6% of aloes, 0.5-0.8% of propolis, 1-1.4% of chlorhexidine acetate, 0.8-1.2% of carbomer 940, 0.08-0.11% of methylparaben, 0.09-0.12% of triethanolamine, 0.9-2.1% of ethanol and 36-40% of purified water. The propolis-aloe bacteriostatic gel is propolis-aloe gel prepared through the compound compatibility of the propolis and the aloes, through the synergistic effect of the propolis and the aloes, the effects of inhibiting the growth of bacteria, promoting wound healing, diminishing inflammation, realizing sterilization, realizing moistening and nourishing, replenishing water, removing acne, removing eczema and realizing spot-fading can be effectively achieved, and especially, the bacteriostatic effect on escherichia coli, staphylococcus aureus, hemolytic streptococcus and the like is achieved.

Disclosed herein is an immunoassay method for detecting the detection target antigen in an analyte through extraction with an extraction agent. The method is characterized in that the detection is performed in the presence of a cyclic oligosaccharide. The method is also characterized in the use of an immunochromatography kit for detecting gram-positive bacteria in an analyte, and that is configured from an analyte dilution solution, a sample dropping part, an antigen extracting part, a labeling substance retaining part, an immunochromatography medium having a detection part, and an absorption part, and in which an organic acid is retained in the antigen extracting part. The immunochrornatography kit contains a cyclic oligosaccharide and a nitrite compound by containing at least one of a cyclic oligosaccharide, a nitrite compound, and a mixture thereof in the analyte dilution solution and/or the sample dropping part.

The nanometer antibacterial erythromycin medicine consists of erythromycin in 0.5-1.5 wt% and nanometer emulsion matrix in 98.5-99.5 wt%. It is yellowish transparent liquid, and has medicine granularity of 1-100 nm, low viscosity, high stability, fast absorption, targeted medicine release, high bioavailability, less toxic side effect and other features. The medicine may be attached well onto bacteria and permeated into bacteria to disturb their metabolism and to reach bacteriostasis and bactericidal effect. It is used mainly for treating serious infection caused by penicillin resisting staphylococcus aureus and hemolytic streptococcus as well as chicken's chronic respiratory tract disease, malignant rhinitis, etc. The medicine has simple preparation process, less toxicity and high safety.

A reagent for the detection of an extracellular enzymatically active protein produced by a beta-hemolytic streptococcus bacteria found in a host biological fluid includes a proteinaceous substrate or a cholesterol-containing membrane substrate for the extracellular protein. The substrate is nonspecific within the groups of beta-hemolytic streptococcus bacterium and is in contact with an inert solid matrix. Upon reaction between the streptococcus enzymatically activate protein and the substrate, a color change discernable by an unaided human eye results. Extracellular streptococcus protein found in saliva represents a less invasive source of biological fluid for the determination as to whether a host suffers acute pharyngitis.

The invention discloses a pharmaceutical composition and composite burn cream for treating burns and scalds and a preparation method thereof. The pharmaceutical composition or the composite burn cream comprises ultra-pure yolk oil and immunoglobulin of yolk with effective treatment dosages, as well as optional pharmaceutically acceptable auxiliary materials, wherein the antigen of the immunoglobulin of yolk is the mycoprotein of one or at least two of staphylococcus aureus, pseudomonas aeruginosa, escherichia coli and hemolytic streptococcus. The composite burn cream can be used for effectively promoting skin regeneration, inhibiting one or at least two of staphylococcus aureus, pseudomonas aeruginosa, escherichia coli and hemolytic streptococcus, and preventing occurrence of infection.

The present invention discloses one kind of Chinese medicine preparation for clearing away heat of throat. The Chinese medicine preparation is prepared with holly root 1-5 weight portions, isatis root 1-5 weight portions, elephantopus 1-5 weight portions, and licorice 1-5 weight portions. The Chinese medicine preparation has high curative effect on influenza, upper respiratory tract infection, tonsillitis, etc. and possesses certain bacteriostasis and killing effect on staphylococcus aureus, type-A hemolytic streptococcus, type-B hemolytic streptococcus, etc.

The invention provides a fennel smoking product which is low in tar content, does not stimulate throats and has the effect of moistening lung and a preparation method thereof. The fennel smoking product is prepared by mixing fennel stem leaves, banana stem leaves and honeysuckle flower vines. In the smoking product, the banana leaves have the effects of moistening lung and intestines, promoting blood circulation and increasing marrow and are rich in potassium, so the content of tar in smoke can be reduced greatly, and the harm to human bodies and the irritation to the throats can be reduced; and the honeysuckle flower vines are rich in pharmacological active ingredients such as chlorogenic acid, luteoloside and the like, has high capacity of inhibiting various pathogenic bacteria such as hemolytic streptococcus, staphylococcus aureus and the like and causative virus of upper respiratory tract infection and the like, and can enhance immunity, protect liver, resist tumors, diminish inflammation, relieve heat, inhibit intestinal tracts from absorbing cholesterol and the like and can prevent the health hidden troubles of people due to the smoke effectively.

The invention discloses a compound herbal disinfectant and a preparation method. The compound herbal disinfectant comprises honeysuckle extracts, wild chrysanthemum flower extracts, indigowoad leaf extracts, ethyl alcohol, water and chlorhexidine acetate. According to the compound herbal disinfectant, pharmacological components such as chlorogenic acid and luteolin in the honeysuckle extracts andwild chrysanthemum flower extracts have strong restraining force for various pathogenic bacteria such as hemolytic streptococcus and staphylococcus aureus and upper respiratory infection causative viruses, active components in the indigowoad leaf extracts have inhibiting effects on the staphylococcus aureus, Neisseria meningitides, typhoid bacillus, escherichia coli and bacillus influenza, and thechlorhexidine acetate has a killing effect on most Gram-positive and gram-negative bacteria. Besides, the bactericidal effect of ethyl alcohol solution is achieved, disinfecting functions of variouscompound herbal plant extracts are mild, skins cannot turn to be rough in disinfection, and the disinfectant is aromatic.

The invention relates to graphene containing paper and a preparation method thereof and discloses an agricultural and forestry residue papermaking technology which comprises the technologies of spiralextruding treatment, steaming and boiling, washing, papermaking, paper modifying and the like. According to the graphene containing paper disclosed by the invention, the agricultural and forestry residues are utilized as a raw material to prepare fibers, and an ultrasonic method and an ethyl alcohol method are matched and utilized; the graphene containing paper prepared by the preparation methoddisclosed by the invention has the advantages of good paper flexibility, high strength and electric conduction function; no harmful chemicals is guided into in the whole process, so that the hygieniccharacteristic of the fibers is ensured. As graphene dispersion liquid is added in a pulping process, an obtained product has better electric-conduction and anti-microbial performance and especially has an effective inhibiting and killing effect on staphylococcus aureus, escherichia coli and hemolytic streptococcus.

The present invention is directed to a method for the ultrasensitive detection of beta hemolytic Streptococcus, a bacterium implicated in strep throat, using a specific protease marker. Also disclosed is a device as well as a biosensor, both of which are useful for the detection of beta hemolytic Streptococcus. The biosensor and the device can be used in conjunction with other reagents as part of a kit for detecting strep throat.

The invention discloses a composition of a yeast fermentation extract. The composition is prepared from the following raw materials in parts by weight: 5-6 parts of the yeast fermentation extract, 1.3-2.6 parts of hyaluronic acid, 15-25 parts of vaseline, 1.3-4.8 parts of carboxymethyl chitosan, 0.7-2.6 parts of arbutin, 0.1-0.2 part of a preservative synergist and 60-80 parts of deionized water. By utilizing a mixture of the taraxacum mongolicum, flos chrysanthemi indici, flos lonicerae, coptis chinensis and folium phyllostachys, a fermentation product contains a large amount of chlorogenic acid and total flavonoids in the whole herb, has an inhibition effect on staphylococcus aureus, hemolytic streptococcus, pneumococcus, corynebacterium diphtheriae and other bacteria and common pathogenic dermatophyte, can improve the immunity of the organism, and has oxidation resistance; and meanwhile, the composition can quickly remove subcutaneous free radicals, has a good anti-wrinkle effect, can relieve irritation and inflammatory injury, caused by superoxide free radicals, to skin tissues, obviously relieve acne symptoms, and accelerate repair of skin lesion parts and focuses.

The present invention provides a dampness-eliminating itching-relieving Chinese medicine preparation with the action of inhibiting dermatomyces, trichophyton violaceum, trichophyton concentricum, achorion schoenleini and bacteria of staphylococcus aureus, hemolytic streptococcus, colibacillus, bacillus pyocyaneus and bacillus proteus, etc. for curing dermatosises with obvious therapeutic effect. Said Chinese medicine preparation is made up by using 10 Chinese medicinal materials of kochia fruit, cnidium seed, silkworm, dictamnus root bark, capillaries, schizonepeta spike and others through a certain preparation process.

The invention discloses applications of Phyllanthus emblica or Phyllanthus emblica and a Phyllanthus emblica composition in preparation of products for preventing and/or treating at least one of mastitis, diarrhea and porcine respiratory diseases, and further provides antibacterial effects of Phyllanthus emblica or Phyllanthus emblica extract and the Phyllanthus emblica composition, wherein the Phyllanthus emblica or Phyllanthus emblica extract and the Phyllanthus emblica composition can effectively inhibit the growth of one or a variety of bacteria selected from Staphylococcus aureus, Streptococcus agalactiae, Pseudomonas, Salmonella choleraesuis, Escherichia coli, Group A beta-hemolytic streptococcus, Streptococcus suis, Bordetella, Pasteurella multocida, Salmonella enterica, Staphylococcus haemolyticus, Enterococcus faecalis and Erysipelothrix rhusiopathiae, and the effectiveness of the uses are proved through experiments so as to expanded the applications of Phyllanthus emblica andthe Phyllanthus emblica composition.

The invention discloses a capsule for treating rhinitis, belonging to the traditional Chinese medicine pharmaceuticals; flower bud of lily magnolia, angelica, ligusticum wallichii, forsythia, baikal skullcap root, corydalis tuber, schisandra chinensis, radix saposhnikoviae, rhizome, asarum and liquorice are used as raw material, the raw materials are prepared into capsules by the conventional preparation process according to different characteristics of each traditional Chinese medicine; the capsule has the functions of relieve rheumatic pains and releasing lungs, clearing away heat and toxic material and relieving stuffiness and relieving pain and is used for syndrome of acute and chronic rhinitis wind-heat retention in lung, such as nasal obstruction, rhinorrhoea and headache and the like and treating both principle and secondary aspects of disease, the curative effect is exact; after pharmacological tests, the capsule is proved to have obvious inhibiting effect on mouse abdominal cavity capillary permeability increasing caused by acetic acid, granuloma hyperplasia induced by implantation of cotton pellets and five disease germs such as B type hemolytic streptococcus, the result shows that the capsule has anti-inflammatory, bacterial inhibition and controlling inflammatory secretion.

The invention relates to a medicament for treating empyrosis, which consists of rhubarb, gallnut, borneol, myrrh, frankincense, radix angelicae and common jujube bark, and is processed into powder, wherein before use, the medicament is blended into thin paste according to a ratio of the medicament to sesame oil being 1:1 and then the paste is applied on the surface of a wound. The medicament has good analgesic effect and can relieve pain in two minutes after application generally, then the pain disappears after 10 minutes, after the medicament is applied for 24 hours, necrotic tissues, secretion are removed automatically and flesh starts to grow, and new granulation tissues grow out quickly; the medicament has strong anti-infection capacity, and plays a role in killing hemolytic streptococcus, pseudomonas aeruginosa, staphylococcus aureus, Escherichia coli, syphilis bacteria and fungi; the medicament has good curative effect, regardless of age of patients and the size of the surface of the wound, skin-grafting or dark curst excision are not needed, no scars are remained after healing, and no side effects are generated; A treatment method is simple and convenient without wound clean and disinfection and is not affected by the environment, and the medicament is applied directly; and medicament has the advantages of simple formulation, production and use, and low treatment cost.

The invention relates to a primer and probe group and kit for detecting hemolytic streptococcus through an RAA fluorescence method, and belongs to the technical field of molecular biological detection. The primer and probe group for detecting the hemolytic streptococcus through the RAA fluorescent method comprises an upstream primer, a downstream primer and a probe; the primer and probe group is characterized in that the nucleotide sequence of the upstream primer is shown as SEQ ID NO.1; the nucleotide sequence of the downstream primer is shown as SEQ ID NO.2; and the probe is a substance which includes the 40th-site base modified fluorescence reporter gene, the 42nd-site base modified tetrahydrofuran residue and the 43rd-site base modified quenching group, and the nucleotide sequence of the probe is shown as SEQ ID NO.3. The kit provided by the invention is rapid and sensitive in detection and simple and convenient to operate; the kit is of great significance to spread of the hemolytic streptococcus in the future; and the kit has a relatively high application prospect.

It is intended to provide a novel instrument for inducing a cytokine and a method of inducing a cytokine by which a cytokine can be effectively induced compared to the existing cytokine induction therapy. Namely, an instrument for inducing a cytokine which contains a hemolytic streptococcus and/or a hemolytic streptococcus-origin component and a water-insoluble carrier; and a method of inducing a cytokine by using this instrument for inducing a cytokine.

The invention belongs to the technical field of screening and application of probiotics, and particularly relates to a Lactobacillus paracasei strain for preventing streptococcus infection of infants and an application of the Lactobacillus paracasei strain. The lactobacillus paracasei has a very strong antibacterial effect on beta-hemolytic streptococcus and is preserved in the China Center for Type Culture Collection on May 24, 2021, and the preservation number of the lactobacillus paracasei is CCTCC (China Center for Type Culture Collection) NO: M2021591. The strain can effectively prevent streptococcus infection, especially streptococcus infection of infants, can significantly reduce the level of inflammatory factors in the body, alleviate the degree of shedding of intestinal mucosa layers, keep the mesenteric structure complete, and alleviate inflammatory cell infiltration and splenomegaly, and has outstanding effects. The lactobacillus paracasei can be used for preparing food, health care products, medicines or skin care products with the function of preventing streptococcus infection, and the application prospect is wide.

The invention relates to an excellent microorganism strain for space mutation, in particular to a good microorganism strain for space mutation, and the preparation method and the application thereof. The discoveries that the bump of a cancer patient infected by hemolytic streptococcus can subsidise naturally and the hemolytic streptococcus and the preparation thereof have a certain of biological activities are made is as early as in the 19th century. In the invention, the special environment of the outer space is utilized to deliver the strains to the outer space through carrying the 22nd recoverable experimental science satellite, the 22nd recoverable experimental science satellite safely returns after traveling for a certain period of time, the suppresormutation strains are eliminated, the forward mutation strains with excellent features are selected out for re-screening, and ultimately the excellent microorganism strains with vigorous life, quick growth speed, high fermentation yield, short fermentation period, high polypeptide content, stable hereditary property, strong productive adaptability and space cumulative effect. The microorganism strain can be applied to the strains for industrialization production, and has the advantages of high output, wide application range, low cost and high effective component content.

The invention relates to a fiber containing graphene/medical planTS and a preparing method thereof, and discloses medical plant paper-making processes including screw extrusion treatment, stewing, washing, paper making, paper product modification and the like. The medical planTS are adopted as raw materials for preparing the fiber, an ultrasonic wave method and an ethyl alcohol method are adoptedin coordination, the paper product containing graphene prepared through the method is good in softness and high in strength, no harmful chemicals are introduced into the whole process, and thus the hygienic characteristic of the fiber is ensured. Besides, the prepared paper product has health care efficacy, and effectively inhibiTS and prevenTS bacteria; the paper product prepared through the method is good in softness and high in strength. Graphene dispersion liquid is added in the pulping process, and thus the obtained product has good anti-bacteria performance and has effective inhibiting and killing effecTS especially on staphylococcus aureus, colibacilli and hemolytic streptococcus.