Patents
Literature
2 results about "Rifamycins" patented technology
Efficacy Topic
Property
Owner
Technical Advancement
Application Domain
Technology Topic
Technology Field Word
Patent Country/Region
Patent Type
Patent Status
Application Year
Inventor
A group of ANTI-BACTERIAL AGENTS characterized by a chromophoric naphthohydroquinone group spanned by an aliphatic bridge not previously found in other known ANTI-BACTERIAL AGENTS. They have been isolated from fermentation broths of Streptomyces mediterranei.
Application of rifamycin in the treatment of colorectal cancer
PendingCN122075482AGrowth inhibitionpromote degradationOrganic active ingredientsDigestive systemPharmaceutical drugActive ingredient
This invention relates to novel uses of pharmaceuticals, particularly the use of rifamycin in the preparation of medicaments for treating colorectal cancer. The application described herein involves rifamycin stabilizing the binding of DHRS4 and LONP2 within the mitochondria of colorectal cancer cells, promoting TFAM degradation, thereby impairing mitochondrial biogenesis and function, and inhibiting mitochondrial activity. In this application, rifamycin is either the sole active ingredient or used in combination with other drugs.
Owner:HARBIN MEDICAL UNIVERSITY
Rifamycin compositions for the treatment of sarcopenia
The present disclosure relates to compositions comprising rifamycin SV and their use in the treatment of sarcopenia. More specifically, the present disclosure describes pharmaceutical compositions comprising rifamycin SV for use in the treatment of sarcopenia in a subject suffering from a chronic disease.
Owner:THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPT OF VETERANS AFFAIRS +1