83 results about "Oxazines" patented technology

The invention relates to the field of hydrogel preparation, and discloses anti-scale zwitter-ion hydrogel as well as a preparation method and application thereof. The method comprises the following steps: firstly, initiating an oxazine derivative monomer to polymerize through a double-end initiator to generate dihydroxyl polyoxazine; and then, removing a side chain of the polymer to obtain the dihydroxy polypropylene imine. Then, dihydroxy polypropylene imine is selected for further reaction to generate a zwitter-ion precursor polymer, and the zwitter-ion precursor polymer is hydrolyzed to obtain the polypropylene imine zwitter-ion derivative. And finally, converting hydroxyl groups at two ends, synthesizing a zwitterionic macromolecular cross-linking agent, and carrying out polymerization cross-linking in an aqueous solution to prepare the anti-scale zwitterionic hydrogel. The hydrogel is simple in formula, is completely composed of the zwitterionic cross-linking agent, has excellent anti-scaling performance such as protein adsorption resistance, bacterial adsorption resistance and cell adsorption resistance, and is suitable for biological materials, medical devices, implant materials and cell delivery materials.

The invention relates to the technical field of silica sol, and discloses a silica sol modified emulsion and a preparation method thereof.The preparation method comprises the steps that silica sol, an emulsifier SR-10, thiazole modified benzoxazine, sodium sulfonate modified thiazole and water are added into a reactor and stirred, and the silica sol modified emulsion is obtained after stirring is finished. Sulfur elements, nitrogen elements, silicon elements, benzoxazine structures and sodium sulfonate groups contained in thiazole modified benzoxazine and sodium sulfonate modified thiazole have good flame retardance; quaternary ammonium salts contained in thiazole modified benzoxazine and sodium sulfonate modified thiazole are adsorbed to the surfaces of thalli, and hydrophobic groups are inserted into lipoid layers, so that the permeability of cell membranes is changed, the membrane structure is destroyed, intracellular substances are leaked, bacterial death is caused, and a relatively good antibacterial effect is achieved.

The invention relates to the technical field of electronic pouring sealants, and discloses a room temperature / UV dual-curing pouring sealant and a preparation method thereof.The room temperature / UV dual-curing pouring sealant is prepared by sequentially feeding acrylic monoester, tripropyl alcohol diacrylate and acrylic acid, evenly stirring, continuing to add 1-hydroxy-cyclohexyl-phenyl ketone and benzophenone, and stirring to obtain a solution A; and continuing to add silane modified polyurethane, modified benzoxazine and epoxy acrylic acid into the solution A, and stirring in vacuum to obtain the room temperature / UV dual-curing pouring sealant. In the stirring process, a terminal hydroxyl group in the silane modified polyurethane, a hydroxyl group in the modified benzoxazine and an epoxy group in the epoxy acrylic acid are subjected to a ring-opening reaction and are cross-linked with one another to form a molecular cross-linked network, so that the connection is tighter, and the mechanical property is improved. A hydroxyl-terminated group in silane modified polyurethane, a silicon element and a phosphorus element in modified benzoxazine and a benzoxazine structure have good flame retardance, a flame-retardant system is formed, and synergistic flame retardance is achieved.

The invention discloses a high-temperature-resistant resin glue solution for a copper-clad plate and a preparation method of the high-temperature-resistant resin glue solution, and relates to the technical field of copper-clad plates. The high-temperature-resistant resin glue solution is prepared from the following raw materials in parts by mass: 60 to 80 parts of dicyclopentadiene phenol type epoxy resin, 20 to 40 parts of fluorinated benzoxazine, 10 to 30 parts of dicyclopentadiene phenol type phenolic resin, 5 to 10 parts of hyperbranched polysiloxane, 90 to 100 parts of solvent, 5 to 8 parts of additive and 10 to 20 parts of inorganic filler. Wherein trifluoromethyl and naphthalene rings are introduced into the fluorinated benzoxazine, so that the heat-resistant stability and the dielectric property of the resin glue solution are effectively improved; a copper-clad plate sample prepared from the resin glue solution has a good application effect.

The invention discloses a fluorinated polypropylene imine (F-PPI) cationic antibacterial agent as well as a preparation method and application thereof. According to the method, F-PPI with adjustable molecular weight is synthesized on the basis of a 2-propyl oxazine monomer. The chemical structure is clear, the molecular weight is uniform and controllable, the fluorinated group is located at the head end of PPI, the controllable degree is high, and the process repeatability and the batch stability are high. The antibacterial efficiency of the cationic polymer can be improved by fluorinated groups and main chain amino cations, and the cationic polymer is endowed with better antibacterial selectivity and biocompatibility according to the characteristics of fluorine elements. End group fluorination modification is carried out in the polymerization process of linear polypropylene imine, and high hydrophobicity and biological inertness of fluoride can be combined, so that the cationic antibacterial agent with low cytotoxicity and high antibacterial efficiency is obtained. The method is simple and convenient in synthesis process, has high repeatability, and is beneficial to construction of high-efficiency and low-toxicity cationic polymers.

The present invention provides a benzoxazine compound made from polyethylene glycol-modified lignin, a resin composition containing the benzoxazine compound, and a cured resin product thereof. Specifically, the present invention provides a benzoxazine compound having a lignin skeleton that is soluble or meltable in an organic solvent, and a method for producing the same. The present invention also provides a resin composition containing the benzoxazine compound that provides a cured product having excellent heat resistance, high strength, and low tensile modulus, and a cured product thereof. [Solution] The present invention relates to a benzoxazine compound containing a reaction product of a novolac-type phenolic resin derived from lignin modified with polyethylene glycol, an amine compound, and an aldehyde compound, a resin composition containing the benzoxazine compound, a cured product of the resin composition, a composite (prepreg, etc.) containing the resin composition and a substrate, the cured product of the composite, and a method for producing the benzoxazine compound.

The invention discloses a preparation method of 2-oxo-4-phenyl oxazine sulfonyl fluoride, and belongs to the field of organic chemical synthesis. According to the method, in a specific tetrahydrofuran solvent, a cinnamyl (fluorosulfonyl) carbamate compound is used as a substrate and reacts under the action of a catalyst and alkali, and the 2-oxo-4-phenyl oxazine sulfonyl fluoride compound is obtained through the reaction. According to the method, iodobenzene diacetic acid and potassium tert-butoxide which are low in price and easy to obtain are adopted as the catalyst and alkali respectively, the substrate applicability is wide, the raw materials are simple and easy to obtain, the economic cost is low, and the target product can be obtained with the good yield.

Disclosed are compounds of formula (I) (including all stereoisomers, N-oxides, and salts thereof), pesticidal compositions containing them, and their use as herbicides, wherein A is a 5- or 6-membered heterocyclic ring containing ring members selected from carbon atoms and up to four heteroatoms independently selected from up to two O, up to two S, and up to four N atoms, wherein one or two carbon or sulfur ring members of the heterocycle may optionally be present in the oxidized form of a carbonyl, sulfonyl, or sulfinyl moiety, said ring being bonded to the remainder of formula (I) through a carbon atom or heteroatom, and wherein one to four R 1 optionally replaced by R 1a , R 1b , R 2 , R 3a , R 3b , R 4a , R 4b , X 1 , X 2 , n, p and q are as defined in this disclosure. [Formula 1] TIFF2025525502000168.tif39170

The invention discloses a method for selectively synthesizing quinazoline-2-ketone sulfonyl fluoride and benzoxazine imine sulfonyl fluoride compounds, and belongs to the field of chemical synthesis of organic fluorine. According to the method, 2-ethynyl-N-[(phenylamino) carbonyl] sulfamoyl fluoride or 2-vinyl-N-[(phenylamino) carbonyl] sulfamoyl fluoride which is low in price and easy to obtain is adopted as the raw materials, the substrate applicability is wide, the raw materials are simple and easy to obtain, and the economic cost is low; in addition, the quinazoline-2-ketone sulfonyl fluoride and benzoxazine imine sulfonyl fluoride compounds can be synthesized in a relatively high yield only in a room temperature environment according to the method disclosed by the invention, and the fluorine-containing building block compounds are widely applied to the fields of medicines, pesticides and click chemistry.

The invention discloses polyurethane automobile finish paint and a preparation method thereof, and relates to the field of automobile finish paint. When the polyurethane automobile finish paint is prepared, titanium dioxide, 3-butene-1, 2-diol and 6-bromine-3-(4-bromophenyl)-2, 4-dihydro-1, 3-benzoxazine are uniformly mixed, and modified titanium dioxide is prepared; carrying out formylation on microcrystalline cellulose, and grafting n-butyric acid, acetic anhydride and 2-aminopiperazine to obtain modified cellulose; the preparation method comprises the following steps: reacting 1, 3, 5, 7-tetramethylcyclotetrasiloxane with vinyl pentamethyldisiloxane to obtain single-ended vinyl hydrogen-containing silicone oil; acrylic acid, methyl acrylate, hydroxypropyl methacrylate and single-ended vinyl hydrogen-containing silicone oil are subjected to copolymerization, and modified acrylic resin is prepared; and uniformly mixing the modified acrylic resin, the modified cellulose, the modified titanium dioxide and various assistants to prepare the polyurethane automotive finish. The polyurethane automobile finish paint prepared by the invention has excellent quick-drying property, impact resistance and aging resistance.

The invention discloses a polysiloxane-based shape memory polymer and a preparation method thereof, and belongs to the technical field of shape memory polymer synthesis. The method comprises the following steps: sequentially adding a formaldehyde solution, a solution dissolved with siloxane and 2-naphthol into a container, and reacting at 90-100 DEG C for 1.5-3 hours; removing the solvent through reduced pressure distillation, then washing liquid residues for multiple times by using deionized water to obtain a product, and drying the product at 60 DEG C for 6 hours to obtain viscous liquid; the liquid is placed in a mold, then the mold is transferred into a drying oven, the temperature is increased to 120 DEG C and 140 DEG C in sequence, heat preservation is conducted for 1 h, finally, the temperature is increased to 190 DEG C to 220 DEG C, the temperature is kept for 5 h to 6.5 h, and curing is completed. The shape memory polymer formed by polymerizing siloxane and 2-naphthol has more Si-O groups, benzene rings and oxazine rings, the groups can enhance the tolerance of the polymer to high temperature, chemical or physical crosslinking points serve as a stationary phase to memorize a permanent shape, and a flexible alkyl-siloxane unit serves as a switching section to fix a temporary shape.

A biomass benzoxazine-based shape memory resin, a preparation method therefor, and an application thereof. The method includes: using biomass furfuryl amine, vanillic aldehyde, and paraformaldehyde as raw materials; obtaining an aldehyde group-containing biomass benzoxazine monomer by means of a heating reaction; mixing the aldehyde group-containing biomass benzoxazine monomer with polyether amine, and obtaining a Schiff base biomass benzoxazine monomer by means of a coupling reaction; and curing the Schiff base biomass benzoxazine monomer to obtain the biomass benzoxazine resin having a shape memory function. The benzoxazine-based shape memory resin has excellent thermal performance, high tensile modulus, high strength; an original shape can be permanently changed according to needs, the defect that traditional cross-linked polymers cannot be reprocessed after being formed is overcome, a recovery function under the condition of heating stimulation achieved, an application range of a shape memory polymer widened due to excellent thermal performance and mechanical performance.

The present invention provides a resin composition and application thereof. The resin composition comprises, by weight, 10 to 70 parts by weight of a benzoxazine resin containing an unsaturated double bond; 20 to 100 parts by weight of a maleimide resin and / or a maleimide prepolymer; and 1 to 30 parts by weight of a double-bond organic silicon compound. The resin composition can maintain excellent heat resistance and high modulus while allowing the final resin composition to have excellent toughness, low water absorption, low dielectric constant and low dielectric loss, and reduce thermal expansion coefficient and warpage.

The application provides an oxazinane compound, a preparation method, a pharmaceutical composition and application, and a general formula of the oxazinane compound or a pharmaceutically acceptable salt thereof is shown as formula (I). The oxazinane compound has obvious proliferation inhibition effect on cancer cells, especially human head and neck squamous cell carcinoma cell strains HSC4, HSC3, HSC2, CAL33, SCC4 and human glioma cell strain U251, can block the cell cycle, effectively inhibit the phosphorylation level of key proteins in the PI3K / AKT / mTOR pathway at the molecular level, has the potential to be prepared into a new antitumor drug, and has a good market prospect.

The present invention relates to the field of the synthesis of polymers. Disclosed are a polypropyleneimine derivative, and a preparation method therefor and a use thereof. The method comprises: firstly, initiating polymerization of an oxazine derivative monomer by means of an initiator, then removing a side chain from a polymer to obtain polypropyleneimine, selecting the polypropyleneimine for a further reaction to obtain a zwitterionic precursor polymer, and finally, hydrolyzing the precursor polymer to obtain a polypropyleneimine zwitterionic derivative. The polypropyleneimine zwitterionic derivative prepared in the present application contains a zwitterionic group in each or some of repeating units. The zwitterionic group endows the polymer with good hydrophilicity and anti-protein non-specific adsorption properties. The polymer has no immunogenicity, will not be recognized by the immune system and captured by immune cells, can be used as a drug carrier and a gene vehicle, and has good blood circulation stability. Alternatively, the polymer is used as a biological material, a medical device, an implantable material, or a cell delivery material and has good anticoagulation, anti-rejection, and biofilm properties.

To provide a liquid crystal sealant that yields a cured product having a high glass transition temperature (Tg) and low moisture permeability.SOLUTION: The present invention relates to a sealant composition comprising: (A) a curable resin containing one or more selected from the group consisting of (A-1) an epoxy resin having two or more functional groups, (A-2) a partially (meth)acrylated epoxy resin of an epoxy resin having two or more functional groups, and (A-3) a (meth)acrylic resin having two or more functional groups; (B) a photopolymerization initiator and / or (C) a thermal curing agent; and (D) a benzoxazine compound.SELECTED DRAWING: None

A composition for the synthesis of oxazine derivatives to provide immunity against pathogenic microorganisms, comprising: 0.01 Mol Schiff base; 0.02 mol 2-methyl-5-oxo-2-phenylthiazolidine-3-carbothioamide; and 0.01 mol N-((4-Bromophenyl)(2-hydroxynaphthalen-1-yl)methyl)-2-methyl-5-oxo-2-phenylthiazolidine-3-carbothioamide.

A crosslinkable thermoplastic resin composition may include a polymer formed from the reaction between a bis-benzoxazine monomer and a bifunctional comonomer having phenol, amine, and / or thiol functional groups, wherein the polymer contains at least one crosslinkable group. A method of forming a crosslinkable thermoplastic resin composition may include reacting a bis-benzoxazine monomer and a bifunctional comonomer to form a polymer containing at least one crosslinkable group. A method of forming a cured thermoplastic resin may include curing the crosslinkable thermoplastic resin composition by applying an external stimulus.

Provided are a resin composition for forming a low dielectric adhesive layer that has good 5G-compatible electrical properties (low dielectric properties), ensures high adhesiveness, suppresses the generation of bubbles, and has a small coefficient of linear thermal expansion (CTE); and an adhesive composition containing the resin composition. The adhesive composition contains a resin composition containing a maleimide resin having a molecular weight of 1000 or more and a benzoxazine resin, and the benzoxazine resin has a site represented by formula (1).In formula (1), R represents a hydrocarbon group having 4 or more carbon atoms. The hydrocarbon group optionally has an unsaturated binding site.

A curable benzoxazine resin composition for a fiber-reinforced composite material is provided which contains at least a component [A], a component [B], and a component [C]. The component [A] includes at least one multifunctional benzoxazine resin having a non-hydrocarbon linkage such as carbonyl, oxygen, sulfur, sulfone or sulfoxide between aromatic moieties. The component [B] includes at least one multifunctional benzoxazine resin having a direct bond or a hydrocarbon linkage between aromatic moieties. The component [C] includes at least one cycloaliphatic epoxy resin containing at least two epoxy groups which are part of cycloaliphatic rings. The curable benzoxazine resin composition is useful in the molding of fiber-reinforced composite materials. More particularly, the curable benzoxazine resin composition makes possible a fiber-reinforced composite material where the cured material obtained by heating has superior performance in extreme use environments, such as high temperature and high compressive load.

The invention relates to the technical field of thin film materials, and discloses a lanthanum gallium silicon thin film material substrate and a preparation method thereof.The preparation method comprises the steps that styrene modified benzoxazine, styrene, a gallium silicon liquid gold compound and lanthanum are added into a double-screw extruder, melt extrusion is conducted, the mixture is added into a model machine, cooling is conducted, and the lanthanum gallium silicon thin film material substrate is obtained; according to the present invention, the rigid benzoxazine structure is introduced into the polyethylene to increase the rigidity of the polyethylene, and is subjected to blending modification with the gallium-silicon liquid gold compound and the lanthanum to improve the mechanical property of the polyethylene, and the benzoxazine can form the heat-resistant phenolic resin structure at the high temperature so as to provide the high thermal decomposition temperature and the high temperature resistance of the lanthanum gallium-silicon film material substrate;

The invention relates to the technical field of thermosetting materials, and discloses a preparation method of benzoxazine and bismaleimide transparent resin alloy, which comprises the following steps: preparing required materials: mixing bismaleimide and benzoxazine according to a certain proportion, adding a proper amount of solvent, and stirring for a period of time to form a uniform mixture; adding a proper amount of cross-linking agent into the mixture, fully stirring, casting a blend solution on a glass plate pretreated with dimethyldichlorosilane, drying at 50 DEG C for 4-6 hours, and then respectively carrying out heat treatment at different temperatures for 1-3 hours to obtain an alloy membrane; and testing the performance of the alloy film. According to the process, bismaleimide and benzoxazine are used as main raw materials, and the transparent bismaleimide resin alloy material with excellent performance is prepared through a specific formula and process steps. The alloy material not only has high transparency and excellent heat resistance, but also has relatively high mechanical strength and chemical stability.

The present invention relates to the use of 3,4-dihydro-2H-benzo-[1,4]oxazine drugs or salts thereof in the preparation of drugs for inhibiting ferroptosis, in particular to the use of 3,4-dihydro-2H-benzo-[1,4]oxazine compounds or salts thereof in the preparation of drugs for treating ferroptosis-related diseases, wherein the ferroptosis-related diseases include brain trauma, stroke, cardiovascular disease, liver and kidney failure, inflammation and neurodegenerative diseases, such as Parkinson's disease and schizophrenia.

The invention belongs to the technical field of polymer composite materials, and provides a PEEK / CF wear-resistant composite material and a preparation method thereof. The wear-resistant composite material is prepared from the following raw materials: PEEK powder, modified CF, B-a type benzoxazine, a compound lubricant, an antioxidant and a dispersing agent, the preparation of the modified CF comprises the following steps: carrying out plasma activation, bifunctional grafting and nanoparticle anchoring on chopped CF to obtain the modified CF; the compound lubricant comprises hydroxylated boron nitride and polyimide micro powder with the particle size of 1-5 microns according to the mass ratio of 2: 1. The preparation method comprises the following steps: (1) mixing PEEK powder subjected to vacuum drying, B-a type benzoxazine, a compound lubricant, an antioxidant and a dispersing agent to obtain a premix; (2) adding the premix and the modified CF into a double-screw extruder, and carrying out melt blending; and (3) after injection molding, cooling and demolding the mold, and drying at constant temperature to obtain the product. According to the preparation method, the wear resistance, the mechanical property, the high-temperature property and the processability of the composite material can be synchronously improved.

Described is a benzoxazine derivative of formula (I) # imgabs0 # (I), also a method for producing a benzoxazine derivative according to the invention, and a kit for producing a recoverable polymer and the use of a benzoxazine derivative according to the invention or a kit according to the invention for producing a recoverable polymer, a recoverable polymer based on polybenzoxazine or polybenzoxazine derivatives, a method for producing a recoverable polymer according to the invention and the use of a recoverable polymer according to the invention as a matrix resin for plastics and / or adhesives and / or composites are also described.

The invention discloses a novel preparation method of balosavir acid, which comprises the following steps: taking a substrate (12aR)-12-[(11S)-7, 8-difluoro-6, 11-dihydrodibenzo [b, e] thia-11-yl]-7-(hexyloxy)-3, 4, 12, 12a-tetrahydro-1H-[1, 4] oxazino [3, 4-c] pyridino [2, 1-f] [1, 2, 4] triazine-6, 8-diketone mesylate, an organic reaction solvent and a dealkylation reagent to react, and separating to obtain the balosavir acid. One or more of sodium thiosulfate and hydrates thereof are added in the reaction process. Sulfur atoms in sodium thiosulfate and hydrate molecules thereof and sulfur atoms in substrate molecules have certain affinity, and form temporary interaction or coordination in the reaction process, so that a reaction product is regulated and controlled to be converted into a dominant spatial configuration, an expected product is generated, the stereoselectivity of the reaction is improved, and the reaction yield is increased. According to the method, the side reactions such as configuration inversion or isomerization of a substrate are reduced, so that the generation of the baloxvir acid in the reaction process is dominant, the generation of an isomer is inhibited, and the purity and the yield of the baloxvir acid are improved through post-treatment solid-liquid separation and purification.

This invention provides a method for preparing 2,2'-(1,4-phenylene)bis-4H-3,1-benzoxazin-4-one, relating to the field of compounds. The preparation method of this invention includes the following steps: (1) reacting anthranilic acid with terephthaloyl chloride in an organic solvent to generate intermediate A; (2) centrifuging the reaction product of step (1) to separate the wet crystalline intermediate A and the centrifugal mother liquor; (3) performing a cyclization reaction between the wet crystalline intermediate A from step (2) and acetic anhydride; (4) centrifuging, washing, and drying the reaction product of step (3) to obtain the target 2,2'-(1,4-phenylene)bis-4H-3,1-benzoxazin-4-one product. This invention prepares 2,2'-(1,4-phenylene)bis-4H-3,1-benzoxazin-4-one with not only low yellowness values ​​and high purity, but also high yield. The preparation method of the present invention has significant industrial value, and is particularly applicable to the field of polymer material additives where strict requirements are placed on product purity and yellowness.

Lipid-polymer conjugates and associated lipid nanoparticles are described herein. Such conjugates can comprise polyoxazolines and / or poly oxazines, thereby obviating the use of PEG-based treatments.

The invention belongs to the technical field of electronic elements, and discloses an electrophoretic paste and a preparation method and application thereof. The electrophoretic slurry is prepared from the following components in parts by weight: 22 to 32 parts of modified epoxy resin, 3 to 7 parts of cationic emulsifier, 0.1 to 0.3 part of silane coupling agent, 10 to 16 parts of benzoxazine crosslinking agent, 50 to 65 parts of solvent, 10 to 20 parts of pigment and 3 to 5 parts of inorganic filler, the modified epoxy resin is a copolyester compound with an epoxy resin group at a terminal group. The electrophoresis slurry obtained by compounding the modified epoxy resin, the cationic emulsifier, the silane coupling agent, the benzoxazine cross-linking agent, the solvent, the pigment and the inorganic filler can be used in an electrophoresis protection layer of the chip resistor, so that the prepared chip resistor still has excellent stability under extreme conditions; the influence of extreme environments (temperature, humidity, overload current and the like) on the performance of the resistor is remarkably reduced, and the stable operation of the resistor in a complex environment can be ensured.