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357 results about "Oxazines" patented technology

Oxazines are heterocyclic compounds containing one oxygen and one nitrogen atom in a doubly unsaturated six-membered ring. Isomers exist depending on the relative position of the heteroatoms and relative position of the double bonds.

Fragrance pro-accords and aldehyde and ketone fragrance libraries

The present invention relates to novel heterocyclic pro-fragrances, preferably oxazolidines, tertahydro-1,3-oxazines, thiazolidines, or tetrahydro-1,3-thiazines, more preferably oxazolidines, or tertahydro-1,3-oxazines, most preferably oxazolidines, which are capable of sustained release of fragrance raw material ketones and aldehydes and to fragrance delivery systems which comprise said pro-fragrances.
Owner:THE PROCTER & GAMBLE COMPANY

3-amino-5-phenyl-5,6-dihydro-2h-[1,4]oxazines

The present invention relates to 3-Amino-5-phenyl-5,6-dihydro-2H-[1,4]oxazines of formula Ihaving BACE1 and / or BACE2 inhibitory activity, their manufacture, pharmaceutical compositions containing them and their use as therapeutically active substances. The active compounds of the present invention are useful in the therapeutic and / or prophylactic treatment of e.g. Alzheimer's disease and type 2 diabetes.
Owner:SIENA BIOTECH +1

Laundry detergent compositions with hueing dye

ActiveUS20050288207A1Easy to optimizeCounter undesirable yellowingDetergent dyesNon-surface-active detergent compositionsNile blue stainOxazine dye
Laundry detergent compositions comprise (a) surfactant, and (b) a hueing dye selected from triarylmethane blue and violet basic dyes, methine blue and violet basic dyes, anthraquinone blue and violet basic dyes, azo dyes basic blue 16, basic blue 65, basic blue 66 basic blue 67, basic blue 71, basic blue 159, basic violet 19, basic violet 35, basic violet 38, basic violet 48, oxazine dyes, basic blue 3, basic blue 75, basic blue 95, basic blue 122, basic blue 124, basic blue 141, Nile blue A and xanthene dye basic violet 10, and mixtures thereof.
Owner:THE PROCTER & GAMBLE COMPANY

Rifamycin analogs and uses thereof

The present invention features rifamycin analogs that can be used as therapeutics for treating or preventing a variety of microbial infections. In one form, the analogs are acetylated at the 25-position, as is rifamycin. In another form, the analogs are deacetylated at the 25-position. In yet other forms, benzoxazinorifamycin, benzthiazinorifamycin, and benzdiazinorifamycin analogs are derivatized at various positions of the benzene ring, including 3′-hydroxy analogs, 4′-and / or 6′ halo and / or alkoxy analogs, and various 5′ substituents that incorporate a cyclic amine moiety.
Owner:ACTIVBIOTICS PHARMA

Amino-Oxazine and Amino-Dihydrothiazine Compounds as Beta-Secretase Modulators and Methods of Use

The present invention comprises a new class of compounds useful for the modulation of Beta-secretase enzyme activity and for the treatment of Beta-secretase mediated diseases, including Alzheimer's disease (AD) and related conditions. In one embodiment, the compounds have a general Formula I wherein A1, A2, A3, A4, A5, A6, L, R2, R7, X, Y and Z of Formula I are defined herein. The invention also includes use of these compounds in pharmaceutical compositions for treatment, prophylactic or therapeutic, of disorders and conditions related to the activity of beta-secretase protein. Such disorders include, for example, Alzheimer's Disease, cognitive deficits, cognitive impairment, schizophrenia and other central nervous system conditions related to and / or caused by the formation and / or deposition of plaque on the brain. The invention also comprises further embodiments of Formula I, intermediates and processes useful for the preparation of compounds of Formula I.
Owner:AMGEN INC

Method for producing thermosetting resin, thermosetting resin, thermosetting composition containing same, molded body, cured body, and electronic device containing those

The present invention provides a method for producing a thermosetting resin having a dihydrobenzoxazine ring structure, characterized by heating and reacting a) a multi-functional phenolic compound represented by the following general formula (I), b) a diamine compound represented by the following general formula (II) and c) an aldehyde compound:wherein X is an organic group containing an aromatic ring and having 6 or more carbon atoms, Y is an organic group having 5 or more carbon atoms, while both X and Y optionally have N, O, F as a heteroatom, and the benzene rings of both sides of X and Y are bonded to different atoms in X and Y.
Owner:SEKISUI CHEM CO LTD

Polybenzimidazole-base complex, crosslinked material of polybenzoxazines formed thereof, and fuel cell using the same

A polybenzimidazole-base complex includes a polybenzimidazole-based material and a base, wherein a peak corresponding to NH of an imidazole ring of the polybenzimidazole-based material does not appear at a chemical shift of 12 to 15 ppm in a 1H nuclear magnetic resonance (1H-NMR) spectrum of the polybenzimidazole-base complex. A crosslinked material may be formed as a polymerization product of a polybenzimidazole-base complex and a benzoxazine-based monomer. The crosslinked material may be used an electrolyte membrane for a fuel cell comprising the crosslinked material, and a fuel cell may include the electrolyte membrane.
Owner:SAMSUNG ELECTRONICS CO LTD

Resin composition for high-frequency high-speed substrate as well as prepreg and laminated board made of resin composition

The invention discloses a resin composition for a high-frequency high-speed substrate. Measured according to solid weights, the resin composition comprises the following components: 10-50 parts of cyanate ester resin (a), 10-40 parts of anhydride compounds (b), 5-50 parts of benzoxazine resin (c), 5-50 parts of epoxy resin (d), 5-50 parts of flame retardant (e), 0-5 parts of curing accelerator (f) and 0-80 parts of inorganic filler (g). The resin composition disclosed by the invention has high moisture and heat resistance, high glass transition temperature as well as lower dielectric constant and dielectric loss tangent value, and can be well applied to the fields such as high-frequency, high-speed and high-density interconnection and the like; and a laminated board made of the resin composition has excellent moisture and heat resistance and good bonding power.
Owner:SHENGYI TECH SUZHOU

Benzoxazine resin composition

InactiveUS20110313080A1Superior resistance to heatIncrease moisturePolymer scienceFirming agent
The invention provides a benzoxazine resin composition having excellent resistance to heat and moisture and providing excellent handleability when made into prepreg, and prepreg and a fiber-reinforced composite material prepared from the composition. The composition contains (A) a compound having in its molecule a benzoxazine ring represented by the formula (1), (B) an epoxy resin, (C) a curing agent, and (D) a toughness improver:(R1: C1 to C12 chain alkyl group, etc., and H is bonded to at least one of C of the aromatic ring at o- or p-position to the carbon atom to which the oxygen atom is bonded).
Owner:SUBARU CORP +1

Activated arylamine-based polybenzoxazines

Arylamines with electron donating groups such as alkyl and alkoxy groups in the meta position on the aromatic ring change the polymerization temperature of the benzoxazine prepared therefrom and offer an opportunity for an additional crosslinking site (the para position on the aromatic amine can couple to a Mannich base generated by the opening of the oxazine ring of the benzoxazine or a methylene bridge generated by a degradation reaction). Naphthenic amines with an alkyl or alkoxy substituent on the 5th through the 8th carbon atom on the naphthalene ring can function similarly. The polymers for benzoxazines prepared from at least 10% substituted aromatic or naphthenic amines are useful due to low polymerization temperatures and higher Tg (glass transition temperature).
Owner:EDISON POLYMER INNOVATION EPIC

Halogen-free flame-retardant thermosetting resin composition of integrated circuit, prepreg and laminate

The invention discloses a halogen-free flame-retardant thermosetting resin composition of an integrated circuit, a prepreg and a laminate. Totaling 100 parts, the resin composition contains the following ingredients in parts by solid weight: (a) 10-50 parts of an allyl modified bismaleimide resin prepolymer, (b) 10-30 parts of an acid-anhydride compound, (c) 5-30 parts of benzoxazine resin, (d) 5-30 parts of epoxy resin and (e) 20-40 parts of phosphoric active ester. The resin composition disclosed by the invention has a high glass transition temperature, excellent moist heat resistance and a relatively low dielectric constant, can better meet the design requirements on multilayer board impedance and is beneficial to application in the field of high-performance printed circuit boards, such as high-density interconnected integrated circuit package.
Owner:SHENGYI TECH SUZHOU

Rifamycin analogs and uses thereof

The present invention features rifamycin analogs that can be used as therapeutics for treating or preventing a variety of microbial infections. In one form, the analogs are acetylated at the 25-position, as is rifamycin. In another form, the analogs are deacetylated at the 25-position. In yet other forms, benzoxazinorifamycin, benzthiazinorifamycin, and benzdiazinorifamycin analogs are derivatized at various positions of the benzene ring, including 3′-hydroxy analogs, and / or various fused ring systems with the benzene ring at the 4′,5′ or 5′,6′ positions.
Owner:ACTIVBIOTICS PHARMA

Oxidative dye composition and indicator

An oxidative dye solution comprises an indicating dye that has been reacted with a reducing agent. The pre-reacted dye when subjected to an oxidizing disinfection or sterilization agent such as peracetic acid or hydrogen peroxide under goes a visible color change and thus can serve as a chemical, process, or chemical integrator, indicator. The dyes include various azines, thiazines, and oxazines compounds and the reducing agents include alkali metal alkyloxides and alkaline earth metal alkyloxide compounds.
Owner:AMERICAN STERILIZER CO

Halogen-free and phosphorus-free epoxy resin composition and prepreg and laminated board produced therefrom

The invention discloses a halogen-free and phosphorus-free epoxy resin composition, which comprises: (a) epoxy resin: 40-80 parts; (b) cyanate resin: 1-15 parts; (c) benzene Oxazine resin: 10-45 parts; (d) aromatic amine compound: 5-30 parts; (e) inorganic filler; the total amount of the above-mentioned components a, b, c, and d is 100 parts; component e Content: the total amount of the first four components is 70~150:100; the monomer of the epoxy resin contains 2 or more benzene rings. The halogen-free and phosphorus-free epoxy resin composition, prepreg and laminate obtained in the present invention can meet the requirements of halogen-free and phosphorus-free flame retardancy, and the flame retardancy reaches UL94V-O level. It not only has environmental protection characteristics, but also has high heat resistance, low Dielectric constant, low dielectric loss, low thermal expansion coefficient, good drilling processability, low water absorption and other excellent characteristics.
Owner:SHENGYI TECH SUZHOU

Synthesis of quinobenzoxazine analogues with topoisomerase II and quadruplex interactions for use as antineoplastic agents

InactiveUS6528517B1Potentiated antibiotic activityPotentiated anticancer activityBiocideOrganic chemistryDNA underwindingType II topoisomerase
The present invention discloses a novel quinobenzoxazine self-assembly complex on DNA and on the topoisomerase II-DNA complex. The related model is used to design a new series of quinobenzoxazines, pyridobenzophenoxazines, pyrridonaphthophenoxazines, and other related compounds that may exhibit anticancer or antibiotic activity. The anticancer activity of these compounds is thought to operate via stabilization of the topoisomerase II-DNA complex and / or interaction with G-quadruplexes, while the antibiotic activity of these compounds derives from their ability to inhibit gyrase, the bacterial type II topoisomerase.
Owner:BOARD OF RGT THE UNIV OF TEXAS SYST

Thermosetting resin having benzoxazine structure and method for producing the same

InactiveUS20100204433A1Improve heat resistanceSatisfactory electrical propertyOrganic chemistryPolystyreneDiol
The present invention provides a thermosetting resin having a benzoxazine ring structure represented by the following formula (I):wherein X is a residue of a diol compound having a molecular weight or a number average molecular weight in terms of polystyrene measured by GPC of 5,000 or less; Y is a residue of a diamine compound; and n is an integer of 2 to 200.
Owner:SEKISUI CHEM CO LTD

3,4-dihydrobenzoxazine compounds and inhibitors of vanilloid receptor subtype 1 (VRI) activity

A 3,4-dihydrobenzoxazine compound of the present invention is represented by the following formula [1] (wherein X is a nitrogen atom or CR3; R1 is a hydrogen atom or a halogen atom; R2 is a C1-6 alkoxy group which may be substituted with the same or different 1 to 5 substituents selected from a halogen atom and a hydroxyl group; and R3 is a halogen atom. However, R1 is a halogen atom when X is CR3). This compound is effective in treating diseases to which the vanilloid receptor subtype 1 (VR1) activity is involved, such as pain, etc.
Owner:JAPAN TOBACCO INC

Oxazinones having antibacterial activity

The invention relates to novel oxazinones designed to bind to the penicillin receptor, methods of synthesizing the compounds, and the use of the compounds as antibacterial agents. The compounds have the general formula (I)Preferably the compounds have a carboxyethyl or a substituted carboxymethyl substituent at the 2-position and a hydroxyl group at the 5-position and have a molecular shape suitable for binding to and reacting with the active site of a pencillin-recognizing enzyme. The compounds are synthesized by condensing a carboxyl-protected N-hydroxy amino acid with a 3-hydroxyprotected-4-bromobutanoic acid to form a a doubly protected N-hydroxy N-acylamino acid, which is cyclized with an organic base to yield a doubly protected 1,2-oxazin-3-one. The protecting groups are then removed to provide an antibacterial agent.
Owner:SIMON FRASER UNIVERSITY

Thermosetting resin composition, and prepreg, laminated board for wiring board and printed wiring board using the same

The present invention discloses a thermosetting resin composition which comprises (A) 35 to 75 parts by weight of a thermosetting resin comprising a compound having a hydrobenzoxazine ring as a main component, (B) 10 to 25 parts by weight of a polycondensation product of a phenol, a compound having a triazine ring and an aldehyde, and (C) 10 to 45 parts by weight of an epoxy resin, based on 100 parts by weight of the total amount of organic solid components of Components (A), (B) and (C), and (i) a bisphenol F epoxy resin having a weight-average molecular weight of 1,000 to 3,000, or (ii) a mixed epoxy resin of bisphenol F epoxy resin and bisphenol A epoxy resin having a weight average molecular weight of 1,000 to 3,000, is contained in Component (C) in an amount of 0 to 100% by weight of Component (C); and a prepreg, a laminated board for a wiring board and a wiring board using the same.
Owner:HITACHI CHEM CO LTD

Pharmaceutical composition comprising n((1-n-butyl-4-piperidinyl)methyl)-3,4-dihydro-2h-(1,3)oxazino(3,2-a)indole-10-carboxamide or salt and process therefor comprising dry granulation

InactiveUS20050075335A1Maximize amount of timeOrganic active ingredientsOrganic chemistryPiboserodExcipient
The invention provides a process for preparing a pharmaceutical composition comprising N-[(1-nbutyl-4-piperidinyl)methyl]-3,4-dihydro-2H-[1,3]oxazino[3,2-a]indole-10-carbixamide (pharmaceutical composition) (piboserod) or a pharmaceutically acceptable salt thereof in combination with one or more pharmaceutically acceptable excipients, the process comprising forming part or all of the (pharmaceutical composition) or the salt thereof into granules by a dry granulation process. The process is preferably a roller compaction process, preferably followed by milling to a suitable particle size. The granules are usually of increased particle size and / or compacted compared to the SB 207266 or the salt thereof. Preferably, the (pharmaceutical composition) or the salt thereof is present in the composition and / or in the granules in at least 4 weight % and / or up to 60 weight % by weight of the composition and / or by weight of the granules respectively. An intragranular lubricant, filler (e.g. CaHPO4), and / or compression aid (e.g. microcrystalline cellulose) are usually used. The invention also provides a pharmaceutical composition obtainable by the dry granulation process and / or which has been prepared by the dry granulation process.
Owner:GLAXO GROUP LTD

Phosphorus-containing benzoxazine-based bisphenols, derivatives thereof, and preparing method for the same

Phosphorus-containing benzoxazine-based bisphenols and derivatives thereof are disclosed. The phosphorus-containing benzoxazine-based bisphenols are prepared by reacting DOPO with benzoxazine to form the phosphorus-containing benzoxazine-based bisphenols. The phosphorus-containing benzoxazine-based bisphenols can further to form advanced epoxy resins. The advanced epoxy resins can further be cured to form flame retardant epoxy thermosets.
Owner:NATIONAL CHUNG HSING UNIVERSITY

Phenazine oxazines dye and application of the same in dye sensitization of solar battery

The invention relates to a phenoxazine dye and a photoelectric converter using the dye, and belongs to the technology field of phenoxazine dyes. The technical proposal is that: the chemical structure of the dye contains substituted phenoxazine and the derivative thereof as electron donors and different conjugated groups as bridging chains, wherein one end of the bridging chains are connected with different electron-withdrawing groups. An electron-donating group on a nitrogen atom and lone-pair electrons on an oxygen atom interact with a chromophoric conjugated system, thereby resulting in more easier charge transfer of the excited state of molecules and generating unique photoelectric property. The phenoxazine dye has good application performance in dye-sensitized solar cells, and can replace expensive noble metal photosensitive dye in dye-sensitized solar cells.
Owner:ZHONGKE ENTERPRISE DEV NINGDE
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