Streptomyces albulus (GS-114) and method of the same to prepare epsilon-polylysine

A technology of Streptomyces parvus and microbial strains, applied in the field of Streptomyces and its preparation of ε-polylysine, can solve the problems of not being suitable for large-scale application in breeding work, general screening effect, and high price, and achieve The effect of excellent passage stability
CN110804572AInactive Publication Date: 2020-02-18JIANGNAN UNIV
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
JIANGNAN UNIV
Publication Date
2020-02-18
Estimated Expiration
Not applicable · inactive patent

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Abstract

The invention discloses streptomyces albulus (GS-114) and a method of the same to prepare epsilon-polylysine, and belongs to the field of microbial fermentation engineering. The provided streptomycesalbulus (GS-114) has resistance to streptomycin, gentamicin and rifamycin with 3 [mu]g / mL, 1 [mu]g / mL and 0.1 [mu]g / mL or higher concentrations, and can efficiently synthesize epsilon-PL in quantity,the yield with 192 h of fermentation can reach 56.3 g / L, and production efficiency can reach up to 7.03 g / L / d. The streptomyces albulus (GS-114) also has good passage stability and has strong potential for the industrial production of the epsilon-PL.
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Description

technical field

[0001] The invention relates to a strain of streptomyces and a method for preparing ε-polylysine, belonging to the field of microbial fermentation engineering.

[0002] technical background

[0003] ε-polylysine (abbreviated ε-PL) is a new type of natural biological food preservative mainly secreted by Streptomyces albulus through liquid aerobic fermentation. ε-PL has a wide antibacterial spectrum, is easily soluble in water, has strong thermal stability and high safety. It has been successively approved as a new food additive by Japan, the United States, South Korea, Europe and China and is widely used in the food industry. At the same time, as a cationic biopolymer, ε-PL is widely used in biodegradable materials, drug carriers, biochip coatings, emulsifiers, high-absorbency hydrogels and anti-cancer enhancers, etc., and has a broad market Application prospect. At present, ε-PL is relatively expensive in the domestic and international markets (about 1200 yu...

Claims

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