30 results about "Mycinamicins" patented technology

The invention provides a pesticide composition containing ningnanmycin. The pesticide composition also contains two ningnanmycin analogs which can effectively prevent and control plant virus diseases, fungus diseases and bacteria diseases separately and together. In addition, the invention also provides a preparation method for the pesticide composition, a prepared pesticide preparation and application of the ningnanmycin analogs and the like.

The invention relates to a pharmaceutic preparation for livestock, comprising silymarin, or silymarin and antibiotics, wherein the antibiotics is selected from beta-lactams, quinolones, tetracyclines, sulfonamides, chloramphenicols or macrolide antibiotics. The test shows that the sensitivity of the antibiotics to the bacterium can be effectively improved, and the drug resistance of the antibiotics to the animal pathogeny can be reduced according to the invitro bacteriostasis test result and the animal invivo test result when the silymarin with a certain concentration is jointly used with the antibiotics, so that the animal bacterial disease can be effectively controlled, the usage amount of the antibiotics in the animal disease can be reduced, the breeding cost can be reduced, the breeding income can be increased, and the safety of the animal-derived food can be improved.

The invention relates to a method for removing residual penicillin antibiotics in biomedical waste residues, comprising the following steps: (1) adding an activator to the biomedical waste residues containing penicillin antibiotics, and obtaining waste residue slurry after slurry mixing and dispersion; 2) Adding a catalyst and an oxidizing agent to the waste residue slurry obtained in step (1), and performing a degradation reaction to complete the removal of the residual penicillin antibiotics in the biomedical waste residue. Compared with the prior art, the present invention can quickly and efficiently remove more than 99% of residual antibiotics, and this method degrades penicillin antibiotics into other non-toxic and non-medicinal substances, and the waste residue obtained from the treatment is solid, which is convenient for storage It can be used for the production of fertilizers and soil conditioners, which conforms to the concept of green, coordinated and sustainable development, and meets the requirements of energy conservation and environmental protection advocated by the state.

The invention relates to a strain of chlamydocetes sporoconiae and its screening and application, and belongs to the technical field of nematicidal biological resources and microbial strains. The Chlamydobacterium chlamydosporia (Pochonia chlamydosporia) YMF 1.00613 was deposited on May 10, 2010 in the General Microorganism Center of China Committee for the Collection of Microorganisms, with the preservation number CGMCC No.3806. The screening step of the bacterial strain includes: separation and purification of the bacterial strain, and screening of secondary metabolites of aurovertins produced by the bacterial strain. The application of the chlamydobacterium Pochonia chlamydosporia YMF 1.00613 strain of the invention in the preparation of agricultural insecticides for preventing and controlling plant pathogenic nematodes and the fermentation production of biological pesticides. The invention has the effect of significantly suppressing the reproduction of pests and the number of offspring populations. The strain PDB fermentation broth and its secondary metabolites, mainly composed of auromycin compounds, have the ability to kill nematodes, and the nematicide activity can reach more than 90% under experimental conditions, and can be used as biologically active substances such as nematicides and biological pesticides fermentation production.

The invention discloses an amicetin compound. The structural formula is shown in the formula I which is shown in the description, wherien R1 is H or shown in the description; R2 is H or OH; R3 is CH3or CH2CH3 or is shown in the description. The amicetin compound has the colon cancer resisting activity. The invention further discloses a preparation method of the amicetin compound. The preparationmethod comprises the steps that rice is fermented by marine actinomycete rice to obtain extracts, and the extracts are separated and purified by using the chromatographic technique to obtain the amicetin compound. Operation and implementation are facilitated. The invention further discloses application of the amicetin compound in preparing a drug for inhibiting colon cancer.

The invention discloses a penicillin antibiotic aptamer obtained by the screening technology for an improved aptamer without a fixed point target substance in the field of screening a penicillin antibiotic aptamer without a fixed point target substance, and an application thereof. The unfixed nucleic acid is eluted through a fixed oligonucleotide library; the parent nucleus 6-APA (6-aminopenicillanic acid) of the penicillin antibiotic is added in positive screening to act on the fixed nucleic acid; after eluting the nucleic acid molecules which can be combined with 6-APA, PCR (polymerase chain reaction) amplification is directly performed for next screening; and other antibiotics are added in negative screening, and the nucleic acid molecules in non-specific binding with the penicillin antibiotics are removed by elution. Through multiple rounds of positive and negative screening, 10 nucleic acid aptamers with high specificity and strong affinity with 6-APA are obtained; and the nucleic acid aptamer with a stable secondary structure is selected for developing a nucleic acid aptamer sensor for detecting 6-APA.

The present invention provides Dab9 derivatives of amphomycin-type lipopepetide antibiotics that display antimicrobial activity against Gram-positive bacteria, methods and intermediates for synthesizing the compounds and methods of using the compounds in a variety of contexts, including in the treatment and prevention of infections.