123 results about "Antibiotic production" patented technology

The invention discloses a treatment method of antibiotic production wastewater. The innovation point is as follows: through an adjusting tank, antibiotic successively enters an iron-carbon micro-electrolysis tank, an FT oxidation tank, a coagulative precipitation tank, an air floatation tank, a treating tank equipped with an anaerobic internal circulation reactor, an upflow sludge blanket filtering basin, a hydrolysis acidification pool, a contact aeration basin and a secondary sedimentation tank so as to undergo recovery processing. According to the treatment method of antibiotic production wastewater, improved iron-carbon micro-electrolysis and improved coal / natural gas indirect liquefaction FT oxidation technologies are adopted for pretreatment, so as to destroy and degrade hardly-degraded and toxic organic pollutants in wastewater. Thus, toxicity is destroyed and water concentration is reduced while biodegradable performance of pollutants in wastewater is improved. Favorable conditions are created for follow-up biochemical treatments, and treatment efficiency and effluent quality standard are raised.

The invention provides a resourceful treatment method for antibiotics mushroom dregs, wherein mushroom dregs produced during production of antibiotics such as penicillin, erythrocin and cephalosporin are treated by the steps of intensified hydrolysis, mushroom dregs blending, two-phase anaerobic digestion, deep dehydration, resource utilization and the like. Aiming at the practical problems of a large quantity of antibiotics mushroom dregs and great treatment difficulty, the antibiotics mushroom dregs are subjected to harmless and resourceful treatment, thus providing basis for difficulties urgent to be solved of pharmaceutical enterprises.

The invention relates to the technical field of antibiotic production, in particular to a daptomycin extraction method. The method includes the following steps of firstly, filtering daptomycin fermentation liquor through a ceramic film; secondly, making filtered liquor pass through large-pore adsorption resin so that eluant can be collected; thirdly, mixing NM-Q anion exchange resin with the obtained eluant, and collecting eluant; fourthly, making the eluant obtained in the third step pass through a reverse phase silica gel MNsil-C18 column, conducting gradient elution on the column through an ammonium acetate ethanol solution, and collecting eluant; fifthly, concentrating the daptomycin eluant obtained in the fourth step, adding calcium acetate and isopropyl alcohol, and conducting standing, crystallization, suction filtration and drying to obtain daptomycin crystallization powder. The method has the advantages that the virulent acetonitrile solution is not used as the eluant, pressure on the environment and health of production personnel is reduced, the use of acid-base regulator is reduced, and the production cost is reduced.

The invention relates to furfural-residue-based biochar, obtained by mixing furfural residue with a dehydrating agent and then performing a carbonization reaction on the mixture. In a preferred technical scheme, concentrated sulfuric acid and soluble sulfate are taken as the composite dehydrating agent, and furfural residue is converted into biochar, which is used for adsorbing antibiotics. The test shows that the surface of the biochar is rich in oxygen-containing functional groups such as carboxyl groups and hydroxyl groups, the highest rates of removing tetracycline and oxytetracycline at initial concentration of 200 mg / l are 98.0% and 95.5% respectively, and the maximal adsorption capacities are 162 mg / g and 335 mg / g respectively. The furfural-residue-based biochar can be applied to wastewater treatment in antibiotic production plants, hospitals and livestock farms.

The embodiment of the invention discloses a treatment method of antibiotic production wastewater. The method includes the steps of conveying antibiotic production wastewater to a Fenton oxidation device to be subjected to Fenton oxidation after the pH of antibiotic production wastewater is regulated to be acidic, conveying wastewater subjected to Fenton oxidation to a membrane separation reactor to be subjected to membrane separation, conveying concentrated water obtained through membrane separation to a photocatalysis reactor, conducting photocatalysis reduction reaction so that Fe3+ in concentrate water can be reduced into Fe2+, discharging or recycling fresh water obtained through membrane separation, conveying concentrated water obtained after the photocatalysis reduction reaction to the Fenton oxidation device, and continuing to process antibiotic production wastewater. Ferrite is added only at the start stage, only pH value regulation and hydrogen peroxide addition are conducted in the later period, and therefore generation of sludge containing iron precipitate is eradicated. Sludge containing iron precipitate does not need to be additionally processed, the processing cost can be reduced, ferrite needs to be added only at the start stage, the use amount of ferrite can be quite small, and the processing cost is further reduced.

The present invention relates to a medium-trace element environmental protection fertilizer with characteristics of plant disease and insect pest resistance and high stress resistance, particularly to a green environmental protection fertilizer comprising a mixture of azadirachtin, matrine, brassinolide and the like and a medium-trace element fertilizer mixture, wherein the fertilizer has effects of effective bacterial killing, prevention and control of the ground and underground plant diseases and insect pests, further has characteristics of no toxic-side effect, no drug residue and no drug resistance, and is the optimal pollution-free product production additive replacing antibiotics, wherein the mixture of azadirachtin, matrine and brassinolide is derived from the natural plant extract. According to the present invention, after using the medium-trace element environmental protection fertilizer, the growth of crops, vegetables and other economic crops is good, the medium-high toxicity chemical pesticide consumption is significantly reduced, the plant diseases and the insect pests are significantly reduced, the farmer pesticide investment is significantly reduced, the yield and the quality of crops are substantially improved, the farmer labor is substantially reduced, the labor activeness is improved, the production efficiency and the benefits of farmers are substantially improved, the food safety is effectively protected, and the purposes of country benefiting and people benefiting are achieved.

The invention provides a pretreatment method of antibiotic production waste water. The method is characterized in that the method comprises the following steps: (1) first level micro-electrolysis; (2) primary coagulating sedimentation; (3) advanced electrocatalytic oxidation; (4) second level micro-electrolysis; (5) secondary coagulating sedimentation. The method mainly aims at deficiency in the prior waste water pretreatment method in the antibiotic production process, and has the advantages of high treatment efficiency and low treatment cost; COD and chromaticity of antibiotic production waste water treated by the process reach the standard.