Antibiotic clean production method

Abstract

The present invention discloses method of the antibiotic clean production, aiming to solve the problem of the treatment of the wastewater in the antibiotic production process with the existing biosynthesis. The method comprises the dilution of the ferment solution and the pretreatment, the filtration, the bleaching, the alkalization and crystallization, and the secondary filtration step. The present invention is characterized in that the process is added with the membrane processing step. The invention has two operational ways: one way is that the membrane processing step is arranged between the filtration and the bleaching, which means that the purified solution is done with the membrane processing; the other way is that the membrane processing step is arranged after the secondary filtration step, which means that the waste mother solution is done with the membrane processing. The use of the method has the following effects: the saving of the clean water resource, the reduction of the wastewater discharge, the improvement of the recycling rate of the product, the repeated use of the chemical additives, the reduction of the investment and running cost of the corporate environmental treatment, the usefulness to the long-term, continuous and stable development of the relative industry and so on. The method is suitable for the transformation of the antibiotic clean production such as the tetracycline, penicillin, aminoglycoside, macrolide and other antibiotics.

Description

Technical field: [0001] The invention belongs to the technical field of biosynthetic production of antibiotics, and also relates to wastewater treatment and reuse technology in the antibiotic production process. technical background: [0002] As we all know, the discharge of waste mother liquor (ie waste water) and the concentration of pollutants in the process of producing antibiotics by biosynthesis (including semi-synthesis) are quite high. According to the different types of antibiotics produced, generally speaking, The discharge of waste mother liquor is as high as 1300-20000m 3 / t, the concentration of COD is as high as 20000-50000mg / l. Moreover, the chemical composition is complex, which not only contains a large amount of antibiotics (about 1000 titer units), but also contains some useful chemicals (such as oxalic acid, etc.) Biodegradable organic wastewater. In the past, biochemical treatment technology was mainly used for the treatment of this kind of wastewater...

AI Technical Summary

Problems solved by technology

Although it has a certain positive effect on the treatment of this type of wastewater, from the perspective of clean production, a large amount of antibiotics and useful chemicals in wastewater are directly converted and consumed, which does not meet the requirements of energy saving and emission reduction, and it is harmful to the industry. Long-term, sustained, and stable development is also unfavorable

Therefore, for more than ten years, this method has not been popularized and applied in actual production

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