12 results about "Oxytetracycline" patented technology

This application discloses a seaweed oligopeptide fertilizer for promoting root growth and seedling development, and its production process, belonging to the field of fertilizer technology. The fertilizer, by weight, comprises: 2-10 parts seaweed oligopeptide complex, 1-8 parts seaweed extract, 10-30 parts compound amino acids, 1-10 parts blueberry pomace, 20-50 parts oxytetracycline waste decomposition products, and 30-60 parts recycled organic matter from kitchen waste. By combining seaweed oligopeptides with chitosan to form a complex, the stability of the active ingredients is improved; simultaneously, the synergistic utilization of oxytetracycline fermentation waste, kitchen waste, and blueberry pomace achieves resource utilization. Experiments show that this fertilizer significantly promotes crop root growth and seedling development.

This invention relates to an oxytetracycline feeding and drying device, belonging to the field of oxytetracycline feeding and drying technology. It includes a mixing bottom trough block and a sealed top trough block. A mixing horizontal tube is rotatably installed on both the left and right sides of the inner wall of the mixing bottom trough block. An air-filling pipe is fixedly installed at the left end of the mixing horizontal tube, while a fixed horizontal rod is rotatably installed at the right end. A combined cylinder is provided at the end of the air-filling pipe and the end of the fixed horizontal rod. Several mixing components are provided on the wall of the fixed horizontal rod, and two connecting rods are symmetrically arranged on one side of the mixing components on the wall of the mixing horizontal tube. A scraper is fixedly installed at the end of each connecting rod near the inner wall of the mixing bottom trough block. This invention, through its mixing structure, achieves uniform material mixing while continuously scraping the inner wall of the storage container, preventing raw material adhesion and accumulation, and avoiding uneven drying or deterioration caused by localized retention, thus significantly improving the overall quality of oxytetracycline drying.

The application provides an engineered oxytetracycline-producing bacterium and a construction method and application thereof. The application takes Streptomyces albus Del14 as a chassis production strain, and successfully expresses an otc cluster in S.albus Del14 for the first time through heterologous reconstitution. Specifically, the otc cluster is expressed by increasing one copy of otcR started by a strong promoter PkasO*; the efflux of OTC is improved by knocking out a negative regulatory factor OtrR in the cluster to release the repression on otrB; further, an efficient OTC production chassis Del14B::oxy1KΔotrR is screened out by replacing an integrase site, and the OTC yield of the chassis Del14B::oxy1KΔotrR reaches 1.1 g / L on the 6th day, which is equivalent to the yield of the original production strain S.rimosus M4018 on the 8th day, so that the heterologous efficient synthesis of OTC is realized.

This invention discloses the application of *Polygonum aviculare* extract in the prevention and control of bacterial leaf spot in peach. The invention utilizes ultrasound-assisted extraction to extract the active components of *Polygonum aviculare*. Antibacterial experiments demonstrated that the extract exhibits good antibacterial activity against the pathogen of peach bacterial leaf spot (*Xanthomonas arboricola* pv. pruni, Xap), with a minimum inhibitory concentration (MIC) identical to that of the positive control drug oxytetracycline, both at 0.125 mg / mL. The antibacterial activity of *Polygonum aviculare* extract is comparable to that of oxytetracycline, making it a potential agent for the prevention and control of peach bacterial leaf spot.

This invention belongs to the technical field of crystalline materials, and discloses a praseodymium-based complex crystalline material, its preparation method, and its fluorescence recognition application, with the chemical formula {[Pr(L 1.5 The compound is 2,2'-(2,3,5,6-tetramethyl-1,4-phenylene)bis(methylene)bis(sulfonyl)diethyl)benzoic acid. The preparation method involves dissolving Pr(NO3)3·6H2O, H2L, and the auxiliary uncoordinated ligand 1,4-bis(imidazol-1-yl)benzene in a DMF / ethanol / water mixed solvent, reacting at 90°C for 3 days, and then cooling to obtain plate-like crystals. This material is effective against Fe... 3+ It exhibits highly selective and sensitive fluorescence quenching response with a quenching rate of 99.8%; it can specifically recognize ethoxyquinoline (fluorescence enhancement) and 2,4-dichlorophenoxyacetic acid (fluorescence quenching); it can specifically recognize the antibiotic oxytetracycline with a fluorescence quenching rate exceeding 99%.

The application discloses a three-dimensional positive-negative general electrode, which is used for adsorbing organic pollutants and comprises a three-dimensional skeleton and an adsorption functional layer; the three-dimensional skeleton and / or the adsorption functional layer has conductivity; the adsorption functional layer is covered on the surface of the three-dimensional skeleton, and the constituent material of the adsorption functional layer comprises one or more of conductive polymers, biochar and synthetic carbon. The electrode has large adsorption capacity and high mass transfer efficiency, can efficiently capture organic pollutants in wastewater, and overcomes the problems of traditional physical adsorbents, such as easy loss and difficult recovery, and the like; when the electrode is used as a cathode or an anode to adjust and adsorb organic pollutants under the cooperation of an electric control, the electrode has stronger adsorption capacity and enrichment capacity. The application further provides a wastewater treatment system, which can quickly and completely treat wastewater, and provides applications of the three-dimensional positive-negative general electrode and the wastewater treatment system in treatment of organic pollutants, such as oxytetracycline, methylene blue, methyl orange and ciprofloxacin.

This invention discloses the application of *Prunus cerasifera* leaf extract in the prevention and control of bacterial leaf spot disease in peaches. The invention utilizes ultrasound-assisted extraction to extract the active ingredients from *Prunus cerasifera* leaves. Antibacterial tests demonstrate that the 80% ethanol extract of *Prunus cerasifera* leaves exhibits good antibacterial activity against the pathogen of peach bacterial leaf spot disease (*Xanthomonas arboricola* pv. pruni, Xap). The minimum inhibitory concentration (MIC) is the same as that of the positive control drug oxytetracycline, both being 0.125 mg / mL. Therefore, it can be used as a raw material for the prevention and control of peach bacterial leaf spot disease.

The application discloses a kind of circulating water aquaculture organic matter and antibiotic targeted adsorption degradation method, belong to aquaculture pond water treatment technical field, steps are as follows: the water outlet of mandarin fish culture pond is introduced into microfilter and retained solid phase pollutants;Water outlet enters raw water pool after buffer tank;Raw water pool water outlet enters biological filter and degrades organic matter;Water outlet flows into molecular imprinting targeted adsorption unit, and antibiotic, hormone are captured by double-targeted molecular imprinting polymer adsorbent;Water outlet enters heterogeneous electrofenton catalytic oxidation unit, and electrolysis is synergized with composite catalyst to catalyze and mineralize pollutant;After water outlet is neutralized pool, into air-lift culture tower reoxygenation and culture beneficial bacteria;After sensor monitoring, water quality reaches standard and then backflow aquaculture pond, otherwise backflow to targeted adsorption unit secondary treatment.The application effectively solves the problems that existing mandarin fish culture circulating water treatment process is difficult to target removal terramycin and other pollutants, which causes accumulation, low adsorption and oxidation efficiency, material easy to inactivate, lack of intelligent control, poor water quality adaptability of effluent.

The present application relates to the technical field of microbial engineering, and particularly relates to a heterotrophic nitrification-aerobic denitrification Pseudomonas azurina ZZU-1 strain capable of degrading antibiotics, a microbial inoculum and application. The present application isolates and screens a Pseudomonas azurina having the ability of simultaneous denitrification and terramycin degradation from a well-operated artificial wetland sediment, and is classified and named as Pseudomonas anuradhapurensis , and is preserved in the China General Microbiological Culture Collection Center, with a preservation number of CGMCC No. 37130. Experimental results show that the strain not only has high efficient simultaneous denitrification ability, but also has good terramycin removal effect. The Pseudomonas azurina strain and the microbial inoculum provided by the present application are expected to be used for denitrification of wastewater containing antibiotics, and can simultaneously remove antibiotics, and have important practical significance for breaking through the biological treatment bottleneck of composite contaminated wastewater.

This utility model relates to the field of wastewater treatment technology and discloses a dual-cathode coupled electrocatalytic antibiotic wastewater treatment device. The device includes a first electrolytic cell, a second electrolytic cell, a wastewater container, a purification container, and a power supply. The first electrolytic cell is equipped with an MMO electrode and a CB-PTFE / GF cracked electrode electrically connected to the power supply. The second electrolytic cell is equipped with a BDD electrode and a FeOCl / GF composite electrode electrically connected to the power supply. The first electrolytic cell has a first inlet and a first outlet connected to the wastewater container. The second electrolytic cell has a second outlet and a second inlet connected to the purification container. The first outlet is connected to the second inlet. This device is simple, produces no secondary pollution, requires no auxiliary devices, and can efficiently degrade antibiotic wastewater, achieving a removal rate of up to 80% for oxytetracycline, levofloxacin, and sulfamethoxazole.

The application provides a terramycin production wastewater treatment device and method for heterotrophic-autotrophic synchronous reinforcement and collaborative denitrification. The device comprises an anaerobic tank, an aerobic tank, an anoxic tank and a sedimentation tank arranged in sequence; the modified zeolite and anaerobic ammonia oxidation bacteria biofilm are arranged in the anoxic tank; the anaerobic digestion effluent enters the anaerobic tank for heterotrophic denitrification; the anaerobic tank effluent enters the aerobic tank after coagulation by polymeric ferric sulfate, short-term nitrification is carried out in the aerobic tank by gap aeration; the anaerobic ammonia oxidation autotrophic denitrification reaction is carried out in the anoxic tank; the nitrate-containing effluent in the anoxic tank is backflowed to the anaerobic tank to realize deep denitrification of the wastewater; the anoxic tank effluent enters the sedimentation tank, and the sludge in the sedimentation tank is backflowed to the aerobic tank to maintain the amount of autotrophic denitrification microorganisms. The application strengthens the heterotrophic and autotrophic denitrification paths step by step, collaboratively improves the denitrification efficiency, solves the problems of carbon source dependence, refractory organic matter and antibiotic inhibition in the traditional process, and high sludge yield, and is suitable for high-concentration terramycin pharmaceutical wastewater treatment.

The application discloses a method and system for improving the methane yield of livestock and poultry manure anaerobic fermentation based on CO2 pressurized hydrothermal pretreatment, and belongs to the field of environmental engineering and biomass energy cross technology.The application introduces CO2 as a "green, reversible and in-situ" chemical additive into the hydrothermal system.Under the conditions of medium and low temperature and pressurization, the substrate modification is realized through the physical and chemical synergistic effects of in-situ acid catalytic depolymerization, ammonia nitrogen form regulation, blocking of side reactions and physical structure blasting.The methane yield of the anaerobic digestion of cow dung can be improved by 30% to 60%.The pathogenic bacteria can be efficiently killed, the residual antibiotics (such as oxytetracycline removal rate of 96.5%) can be degraded, and the risk of drug resistance gene diffusion can be reduced.The whole process does not use strong acid and alkali, and there is no secondary pollution;CO2 can be recycled in a closed loop by using the by-product of biogas purification, and the system has positive net energy output by cooperating with heat recovery technology, so the system has broad industrialization prospect.