The invention belongs to the technical field of new material preparation and relates to a preparation method of blocky hybrid aerogel which specifically refers to blocky aerogel fast prepared under the normal pressure condition and has an efficient removing effect on Cd2+ in waste water. The preparation method includes the steps that firstly, tetraethyl orthosilicate, deionized water, acetonitrile and an oxalic acid solution are measured and taken and are mixed, and the mixture is placed in a water bath kettle to react; after reaction, a beaker is taken out, 3-aminopropyltriethoxysilane is transferred into the beaker through a pipette when temperature returns to room temperature, and acetonitrile is added for aging after gelation; then gel is soaked in an acetonitrile solution containing isophorone diisocyanate and is placed in the water bath kettle for crosslinking; finally, acetonitrile is added, after standing performed under room temperature, the gel is sealed through a preservative film with needle holes and placed in a normal-pressure drying oven to be dried, and the silicon dioxide blocky hybrid aerogel is obtained. In the preparation process of the blocky hybrid aerogel, no solvent exchange or surface modification exists, consumed time is short, consumed energy is little, operation is easy, and the blocky hybrid aerogel has an efficient adsorbing effect on Cd2+ in waste water.