1510 results about "Alkoxyl radicals" patented technology

A compound of formula (I) or a pharmaceutically acceptable salt or hydrate thereof wherein X-Y is -NHSO2- or -SO2NH-; R1 is H, CN or alkyl; R2 is selected from COOH and a tetrazolyl group; R3 is selected from H, Cl and alkyl; R4 is selected from H and halo; R5 is selected from H, alkyl, haloalkyl, SO2-alkyl, Cl, alkoxy, OH, CN, hydroxyalkyl, alkylthio, heteroaryl, cycloalkyl, heterocycloalkyl and haloalkoxy; R6 is H; R7 is selected from H, CN, haloalkyl, halo, SO2-alkyl, optionally substituted heteroaryl, SO2NR14R15, CONR10R11 and alkyl; R8 is selected from H, alkyl, haloalkyl and halo; R9 is H or halo; and R10, R11, R12, R14, and R15 are H or alkyl; R13 is selected from alkyl, halo, alkoxy, CN, haloalkyl and OH; and m is 0-3. The compounds of formula (I) modulate ERAP1 (endoplasmic reticulum aminopeptidase 1) and are for use in treating proliferative, immune or inflammatory disorders, particularly cancer or leukemia. The compounds of formula (I) stimulate a neo-antigen directed immune response in the subject. A method for producing an antigen-presenting cell which presents a neo-antigen using compounds of formula (I) is disclosed. An immunogenic composition comprising an antigen-presenting cell is also disclosed. Exemplified compounds include 4-cyclopropyl-3-(N-(2-(morpholin-3-yl)-5-(trifluoromethyl)phenyl)sulfamoyl)benzoic acid.

The invention provides a photosensitive resin composition containing a photobleaching aminomethyl anthracene photosensitizer and application thereof.The structural main body anthracene ring of the photosensitizer introduces an aminomethyl functional group to the 9th and / or 10th site: through introduction of the aminomethyl functional group, while the electron cloud density of polycyclic aromatic hydrocarbon is maintained, the maximum absorption wavelength is subjected to red shift, and the photosensitive resin composition is especially suitable for a 405nm illumination system; the initiation efficiency is obviously improved; the exposure energy is reduced; compared with an existing DBA type photoinitiator, the problem of alkoxy carbon-oxygen bond breakage caused by p-pi conjugation of DBA is avoided, generation of small molecule fragments is effectively inhibited, defects are reduced, and the yield is increased. In addition, compared with DPHA and DAcOA, the photosensitizer also shows better solubility and formula compatibility. The preparation method has the characteristics of simple preparation process and low cost, and can be widely applied to the photocuring fields of dry films, paints, coatings, printing inks, forming materials and the like.

The need for a liquid hand dishwashing detergent composition which provides for effective cleaning, as well as enhanced foaming, is met by formulating the composition with a surfactant system which comprises alkyl sulfated anionic surfactant having little or no alkoxylation, an amphoteric and / or zwitterionic co-surfactant, and nonionic surfactant, in combination with a mid-chain 1,2-alkanediol.

The invention relates to a rubber blend, to a sulfur-crosslinkable rubber mixture comprising the rubber blend and to a vehicle tire comprising such a rubber mixture.The rubber blend comprisesat least one solution-polymerized diene polymer A of high molecular weight andat least one solution-polymerized polymer B of low molecular weight,wherein at least one of polymers A and B has been functionalized at the chain end and / or along the polymer chain and / or at a coupling site with at least one group selected from epoxy groups, hydroxyl groups, carboxyl groups, silane sulfide groups, amino groups, siloxane groups, organosilicon groups, phthalocyanine groups and amino group-containing alkoxysilyl groups.

The invention provides a photosensitive resin composition containing an anthracene methyl modified melamine photosensitizer, a photosensitive dry film and application of the photosensitive dry film, the photosensitizer adopts a melamine skeleton to connect three anthracene 9-methyl structures, and through a rigid structure of the melamine skeleton and a methylene bridging (-CH2-An) design of an anthracene group, the photosensitive resin composition has the remarkable advantages that the methylene bridging structure can be used for preparing a photosensitizer, and the photosensitizer can be used as a photosensitizer for photosensitization of the anthracene methyl modified melamine photosensitizer. The breakage of carbon-oxygen bonds on alkoxy caused by p-pi conjugation is avoided, so that the migration of small molecular fragments after initiation is reduced, permeable crystallization to a polyethylene protective film is effectively inhibited, and the risk of short circuit of a line is remarkably reduced; the light quantum yield can be greatly improved by introducing a plurality of light sensing units; the melamine skeleton is used, so that the adhesive force of the initiation system on the metal foil surface can be effectively improved; in addition, the photosensitizer also shows excellent solubility and formula compatibility, and can be widely applied to the photocuring fields of dry films, paints, coatings, printing inks, molding materials and the like.

The invention relates to the technical field of organic silicon coatings, in particular to a preparation method of an organic silicon antifouling coating for slowly releasing a lubricant. The preparation method of the organosilicon antifouling coating of the slow-release lubricant comprises the following steps: carrying out emulsion polymerization on silicon dioxide nanoparticles, acryloyloxy alkyl alkoxy silane, fluorine-containing acrylate and lubricating oil in a redox system to obtain a fluorine-silicon modified silicon dioxide nanoparticle emulsion of which the surface is attached with the lubricating oil; and then mixing with organic silicon resin, a coupling agent, a cross-linking agent and a catalyst, and carrying out cross-linking curing to obtain the organic silicon coating. The lubricating oil is adsorbed on the surfaces of the nano particles under the action of grafted functional groups of the functionalized nano particles, so that the lubricating oil is introduced into the organic silicon coating in the form of emulsion particles, micro-nano lubricating oil droplets are formed, long-acting slow release of the lubricating oil is realized, the amphiphobic property and low surface energy of the coating are improved, and the antifouling capacity of the coating is improved; meanwhile, the mechanical property is improved.

The invention relates to a passivation layer, a perovskite solar cell, a preparation method of the perovskite solar cell, a laminated cell and a photovoltaic module. The passivation layer comprises a compound shown in a formula (I): # imgabs0 #; wherein R1 to R5 are respectively and independently selected from one of hydrogen, halogen, amino, hydroxyl, cyano, sulfydryl, substituted or unsubstituted C1-C8 alkyl and substituted or unsubstituted C1-C8 alkoxy. The carboxyl hydroxyl group in the compound and BX2 with unsaturated coordination number on the surface of the perovskite thin film can form a coordination bond, so that surface defects of the perovskite thin film are effectively passivated, non-radiative recombination on the surface of the perovskite thin film is inhibited, and the photoelectric conversion efficiency of the perovskite solar cell is further improved.

The invention discloses a hot and moisture dual-cured organic silicon sealant and a preparation method thereof. The organic silicon sealant is prepared from the following raw materials: hydroxyl-terminated methyl vinyl polysiloxane, alkoxy-terminated polydimethylsiloxane, active nano calcium carbonate, fumed silica, a cross-linking agent, a catalyst and a tackifier. The organic silicon sealant organically combines the advantages of a condensation type curing system and an addition type curing system, can be quickly positioned and cured, is high in strength, good in adhesion, excellent in temperature resistance and long in storage life after being cured, and can be used for various occasions needing quick positioning and assembling.

The invention discloses a multi-target anti-tumor active rutaecarpin derivative or a pharmaceutical salt thereof. The structural general formula of the rutaecarpin derivative or the pharmaceutical salt thereof is shown as a formula I or a formula II: # imgabs0 #, wherein R1 is selected from C1-C5 alkoxy, hydroxyl and hydrogen; r2 is selected from hydrogen and halogen; according to the present invention, the enzyme inhibition activity and in vitro anti-tumor activity test results show that the compound of the present invention has strong inhibition activity on topoisomerase 1, topoisomerase 2 and c-MYC oncogenes, such that the new approach is developed for the deep research and the development of the new structure type anti-tumor drug, and the new strategy is provided.

The invention discloses a kind of preparation method of amino hyperbranched siloxane and its modified polyimide aerogel material.First, alkoxysilane X with amino active functional group, alkoxysilane Y of inactive functional group and water are carried out autocatalytic controlled hydrolysis condensation under sub-stoichiometric ratio, obtain multifunctional group (such as other active groups, alkoxyl group, amino) amino hyperbranched siloxane liquid (HPSi NH2) with controllable amino content, then using HPSi NH2 as cross-linking agent and anhydride-terminated polyamic acid solution reaction to obtain functionalized polyamic acid, which is stirred with tertiary amine and deionized water to obtain functionalized polyamic acid wet gel, which is passed through freeze drying, high temperature imidization treatment to obtain amino hyperbranched siloxane modified polyimide aerogel material. This material has excellent flexibility, resilience, heat resistance and flame retardancy, and can be applied to aerospace, communication, catalysis and filtration fields.

The invention discloses a polymerizable compound, a liquid crystal composition containing the polymerizable compound and a liquid crystal display device. The polymerizable compound is a compound shown as a formula I, in the formula I, # imgabs 0 # and # imgabs 1 # are respectively and independently represented as # imgabs 2 #, # imgabs 3 # or # imgabs 4 #, and # imgabs 5 # and # imgabs 6 # are not simultaneously represented as # imgabs 7 #; any hydrogen in the # imgabs8 and # imgabs9 can be substituted by alkyl or alkoxy of C1-C5, alkenyl or alkenyloxy of C2-C5, alkyl or alkoxy of C1-C5 substituted by fluorine, alkenyl or alkenyloxy of C2-C5 substituted by fluorine and halogen, and any one or more of-CH2-which is not connected can be independently substituted by-O-,-S-,-CO-,-CH2O-,-OCH2-,-COO-and-OOC-respectively. The polymerizable compound has the advantages of small SEM particles after polymerization and excellent diffusivity and antistatic performance. When being used in a liquid crystal display component, the liquid crystal display component has the advantages of good uniformity, rapid static electricity release and avoidance of bad display phenomena such as broken bright spots. And # imgabs10 # I is adopted.

The invention discloses solvent-free hydrophilic block silicone oil and a preparation method thereof, and the method comprises the following steps: carrying out equilibrium reaction on chloropropyl alkyl alkoxy silane and hydroxyl-terminated polydimethylsiloxane in an acid catalyst to prepare linear silicone oil of which the two end structures are chloropropyl alkyl alkoxy; the linear silicone oil is neutralized and filtered and then reacts with tertiary amine, and the quaternary ammonium salt-terminated hydrophilic block silicone oil is prepared. According to the method, no solvent participates in the whole synthesis process of the block silicone oil, a monomer polymerization process is adopted, and compared with a traditional method, operation is easy, raw materials are easy to obtain, cost is low, and the process saves energy, reduces consumption, is environmentally friendly and is suitable for industrial production of a monomer factory. The block silicone oil prepared by the invention has excellent hydrophilicity, and can endow fabrics with excellent fluffy, soft and smooth handfeel and hydrophilic performance when being used as a finishing agent for fabrics such as cotton, polyester, polyester cotton and the like.

To provide: a method for producing an anti-thrombogenic material in which white turbidity is reduced; a method for producing a medical instrument coated with the anti-thrombogenic material produced by the method; and an anti-thrombogenic material in which white turbidity is reduced.SOLUTION: A method for producing an anti-thrombogenic material according to the present invention comprises a step of copolymerizing a specific alkyl (meth)acrylate, a silicone (meth)acrylate, and an alkoxy polyethylene glycol (meth)acrylate, wherein the silicone (meth)acrylate used here has a weight average molecular weight of 1450 or less.SELECTED DRAWING: None

A water-soluble unit dose article containing a non-soap anionic surfactant and non-ionic surfactant, where the non-ionic surfactant includes first and second alkoxylated alcohol non-ionic surfactants. A related process of laundering fabrics.

The invention provides lithium ion selective resin containing alkoxy grafted 2-hydroxybenzophenone (or aldehyde) functional groups as well as a preparation method and application of the lithium ion selective resin. The lithium ion selective resin disclosed by the invention has very strong chemical structure stability and high lithium-sodium separation factor in a wide pH range.

The invention discloses a solid electrolyte and a preparation method and application thereof, and belongs to the technical field of electrochemical energy storage. The invention provides an application of a compound I in preparation of a solid electrolyte, and the structural formula of the compound I is as follows: # imgabs0. Through the design of a molecular structure, the compound I keeps low polarity, meanwhile, a functional group alkoxy capable of weakly coordinating with electrolyte ions is introduced, multiple optimization of the performance of the compound is realized, and by introducing the compound I, the performance of the solid electrolyte is improved. The method can greatly improve the comprehensive performance of the solid electrolyte, including ionic conductivity, electrochemical stability, electrode interface compatibility and the like, and is also beneficial to simplifying the preparation process of the solid electrolyte, thereby providing important technical support for developing a new generation of high-performance solid electrolyte and solid battery. And further development of an electrochemical energy storage technology is expected to be promoted.

The invention provides a photo-thermal response T-type liquid crystal molecule, a preparation method thereof and application of the photo-thermal response T-type liquid crystal molecule to an intelligent window. The structural formula of the T-type liquid crystal molecule is shown in the formula (1). According to the technical scheme, the liquid crystal molecule is in a T type, an azobenzene structure in the liquid crystal molecule is subjected to reversible conversion of cis and trans under switching of ultraviolet light and visible light, and meanwhile, a molecular structure of 8CB and a butylene adipate structure can be subjected to phase change at room temperature, so that the molecule has a light response function, and meanwhile, the light response effect of the molecule is improved. The material also has a thermal response function at room temperature; besides passive control through light and heat, after electrification, liquid crystal molecules are arranged in order, an electric response function is achieved, and the intelligent window can be actively recovered to be transparent. The molecule not only has multiple responses, but also is a low-carbon environment-friendly material. According to the technical scheme, the alkoxy chain is linked to the side chain of the liquid crystal molecule, asymmetry is increased, the liquid crystal molecule has a richer phase structure, and the liquid crystal molecule has a huge development prospect in the field of intelligent windows.

The present invention relates to a compound of formula (I) A-L1-RCG1 (I) wherein A is of formula (A), R1 is H, an optionally substituted alkyl, alkenyl, alkynyl, R2 is halogen, alkyl; alkenyl; alkynyl; alkylthio; alkylthioalkyl; alkyl-S(O)-; alkyl-S(O2)-; alkyl-S(O)-alkyl-; alkyl-S(O2)-alkyl-; alkoxy; alkoxyalkyl; haloalkoxyalkyl; cycloalkyl-O-alkyl; alkyl-NH- alkyl; (alkyl)2-N-alkyl; alkyl-NH; and (alkyl)2N; R3 is deuterium; H, alkyl; alkenyl; alkynyl; alkylthio; -OR6, -NR7R8, heterocycloalkyl, heteroaryl, aryl, cycloalkyl; L1 is a linker, RCG1 is a reactive chemical group. The present invention also relates to a compound of formula A- L1-G-BA (II) wherein G is the product of reaction between RCG1 and a reactive group RCG2 and BA is a binding agent, a pharmaceutical composition comprising it and its therapeutic uses, for instance for treating cancer.

The invention discloses trialkoxy functionalized polysiloxane and a preparation method and application thereof.The trialkoxy functionalized polysiloxane has the structural formula shown in the specification, a trialkoxy group is designed in the middle chain segment of polysiloxane, and the group can react with hydroxyl on the surface of filler to be connected, so that the functionality of the polysiloxane is improved, and the service life of the polysiloxane is prolonged. The surface of the filler is coated with an organic layer composed of two hydrophobic polysiloxane chain segments and one methyl group. As a polysiloxane chain segment generated on the surface of the filler is the same as the molecular structure of a polysiloxane matrix, the inorganic filler treated by the technical scheme not only has good stability in the polysiloxane matrix, is not easy to settle, but also has a higher filling coefficient, and is particularly suitable for preparing a thermal interface material with a high heat conductivity coefficient. # imgabs0 #

The invention belongs to the technical field of pesticides, and particularly relates to a triazine ring substituted phenylsulfonyl urea compound, a preparation method therefor, a herbicidal composition and a use. The compound is as shown in general formula I, wherein Z is hydrogen or alkyl; R is alkyl, haloalkyl or alkoxy. The compound has excellent herbicidal activity on gramineous weeds, broadleaf weeds etc.

The invention relates to an ammonium polyphosphate microcapsule flame retardant, and belongs to the technical field of flame retardant materials. The ammonium polyphosphate microcapsule flame retardant is prepared by a method comprising the following steps: carrying out emulsion polymerization reaction on ammonium polyphosphate, an alkenyl silane coupling agent and a borosilicate polymeric monomer under the action of an organosiloxane / persulfate redox system containing Si-N bonds; the borosilicate polymeric monomer is prepared by carrying out condensation reaction on alkenyl trialkoxy silane and boric acid, and the mass ratio of the alkenyl trialkoxy silane to the boric acid is (14-15): (6-7). The ammonium polyphosphate microcapsule flame retardant disclosed by the invention does not need an organic solvent during preparation, and is simple in operation process, low in toxicity, convenient to produce, easy to control, safe and environment-friendly.

The need for a liquid hand dishwashing detergent composition which provides for effective cleaning, as well as enhanced foaming, is met by formulating the composition with a surfactant system which comprises alkyl sulfated anionic surfactant having little or no alkoxylation, an amphoteric and / or zwitterionic co-surfactant, and nonionic surfactant, in combination with a mid-chain 1,2-alkanediol.

The invention provides an electrolyte and a lithium ion battery. The electrolyte comprises the following components in percentage by mass: 10-18% of lithium salt; 0.5%-10% of a film forming agent; 0.05%-5% of an impregnating compound; and the balance of a solvent; the structural formula of the impregnating compound is # imgabs0, R1-R6 are independently selected from any one of sulfonate groups, hydrogen, halogen, substituted or unsubstituted C1-C10 alkyl groups, substituted or unsubstituted C1-C10 alkoxy groups, substituted or unsubstituted C3-C10 cycloalkyl groups, substituted or unsubstituted C2-C10 alkenyl groups and substituted or unsubstituted C2-C10 alkynyl groups, and at least one substituent group in the R1-R6 is halogen or sulfonate groups. The electrolyte has relatively low impedance, so that the cycle stability of the lithium ion battery under a fast charge condition is favorably improved.

The invention provides a dispersing agent composition for dispersing a lithium iron phosphate precursor, a lithium iron phosphate positive electrode material and a secondary battery. The dispersing agent composition comprises a first dispersing agent and a second dispersing agent; the first dispersing agent is selected from any one or a combination of at least two of sulfonate, sulfate, organic ammonium salt, polyoxyethylene ether, cross-linked modified polyoxyethylene, phosphate and derivatives thereof, alkoxy polyethylene glycol silane, polyhydroxy alcohol or high fructose corn syrup; the second dispersing agent is selected from any one or a combination of at least two of polyoxyalkylene ether and a derivative thereof, polyether modified polysiloxane, unsaturated carboxylate and a derivative thereof, quaternary ammonium salt, alkyl sulfonate, alkyl sulfonate, polyethylene glycol and a derivative thereof or polyamino amide. The dispersant composition provided by the invention not only can significantly improve the solid content of the lithium iron phosphate precursor, but also can reduce the water consumption in the preparation process of lithium iron phosphate.

The invention relates to a conductive adhesive composition and a conductive article. In particular, the present invention provides a conductive adhesive composition. The present invention relates to a pressure sensitive adhesive composition comprising: a pressure sensitive adhesive matrix comprising at least one non-linear block copolymer comprising an aromatic terminal block and an aliphatic elastomer block; at least one hydrocarbon-based tackifying resin; at least one aromatic reinforced resin; and conductive particles dispersed within the matrix. In some cases, the composition further comprises: an adhesion promoter comprising an alkylalkoxysilane, an alkenylalkoxysilane, an alkylphosphonic acid, or an alkylcarboxylic acid; and optionally, a non-functionalized dipodal alkoxysilane, and a method for preparing the same. When the adhesion promoter comprises an alkyl alkoxysilane or an alkenyl alkoxysilane, a non-functionalized dipodal alkoxysilane is present. In other cases, the composition also includes an adhesion promoter comprising an organic molecule selected from the group consisting of organic compounds capable of forming a bond with the surface of the metal oxide. Also provided is a conductive article comprising a substrate and a conductive adhesive disposed on the substrate.

There is provided a method of making an alkoxy silicate-based aerogel material, the method comprising: hydrolysing an alkoxy silicate in a hydrolytic solvent to form a silica sol for a pre-determined period of time and at a pH of 1-4; mixing the silica sol with a basic solution to form a sol-gel; a first ageing the sol-gel; adding a surface-modifying agent to the sol-gel; a second ageing the sol-gel; and heating the sol-gel at a temperature of 120-250° C. to form the alkoxy silicate-based aerogel material, wherein the alkoxy silicate-based aerogel material has a thermal conductivity of <18 mW / mK. There is also provided an alkoxy silicate-based aerogel material formed from the method.

The invention provides a lithium ion battery electrolyte and application thereof. The electrolyte comprises: a non-aqueous solvent; a lithium salt; the additive comprises a first additive and a second additive, the structural formula of the first additive is a formula A, and the second additive is selected from a compound with a structural formula B1 or a structural formula B2; in the formula 1, n1 and n2 are respectively and independently any natural number from 1 to 3, and R1, R2, R3, R4 and R5 are respectively and independently selected from any one or a combination of more of-H,-F, C1-6 alkyl, C1-6 alkoxy, C2-6 alkenyl, C2-6 alkenyloxy, C2-10 alkynyl, C2-10 alkynyloxy, C3-8 cycloalkyl, C3-8 epoxy alkyl, C6-12 aryl, C6-12 heteroaryl or carbonyl, trifluoromethyl and C2-6 ester. According to the lithium ion battery electrolyte and the application thereof provided by the invention, gas production can be effectively inhibited, and the fast charging performance and the high and low temperature performance of the lithium ion battery can be improved.

The invention belongs to the field of heat conduction materials, and particularly relates to gradient interface modified aluminum oxide-aluminum nitride bi-component heat conduction filler and a preparation method thereof, and the gradient interface modified aluminum oxide-aluminum nitride bi-component heat conduction filler comprises spherical aluminum oxide, flaky aluminum nitride and double gradient modified layers coating the surfaces of the spherical aluminum oxide and the flaky aluminum nitride; the D50 of the spherical aluminum oxide is 2-5 microns, and the sphericity is greater than or equal to 0.85; the sheet-shaped aluminum nitride is in a hexagonal sheet shape, the average particle size is 8-12 microns, the thickness is 200-500 nanometers, and the radius-thickness ratio is 20-50; the mass ratio of the spherical aluminum oxide to the flaky aluminum nitride is (40-70): (30-60); the double-layer gradient modification layer comprises an inner-layer hydrophobic silane layer and an outer-layer reactive silane layer, the inner-layer hydrophobic silane layer is formed by grafting alkyl trialkoxy silane with the carbon chain length of 8-16, the outer-layer reactive silane layer is formed by grafting a silane coupling agent containing an epoxy group or an amino group, and morphological complementary optimization of a filler network is achieved.

The invention relates to the technical field of organic silicon resin preparation, in particular to trapezoidal methyl silicon resin and a preparation method thereof.The trapezoidal methyl silicon resin is prepared by taking methyl trichlorosilane as a main raw material, introducing a trapezoidal control agent containing amido and alkoxy at the same time to inhibit the reaction activity of the methyl trichlorosilane and then carrying out hydrolysis reaction in a small amount of alcohol solvent and water; the generation of a cross-linked network structure insoluble substance during hydrolysis is avoided, and the resin gelation risk is effectively reduced. The hydrolysis rate is reduced, so that the use amount of the solvent is reduced, the proportion of alcohol in the water phase is greatly reduced, and the process and environmental protection cost is reduced. The trapezoidal methyl silicone resin prepared by the method is excellent in viscosity performance, high in yield, excellent in boiling resistance, short in curing time, high in resin softening point and short in gelation time.

The invention relates to the technical field of organic synthesis and the technical field of fluorescent materials, in particular to a boron coordination salicylhydrazone double-state emission fluorophore as well as a preparation method and application of the boron coordination salicylhydrazone double-state emission fluorophore. The structure of the boron coordination salicylazone double-state emission fluorophore is shown as I, II or III; wherein R1 is selected from one of H, halogen atoms, diethylamino and thienyl, R2 is selected from one of H, halogen atoms, diethylamino and thienyl, and R3 is selected from one of aryl, 9, 9 '-spirobifluorenyl, alkoxy and halogen atoms. The boron coordination salicylazone double-state emission fluorophore is diversified in structure and good in solubility, has excellent photophysical properties and extremely high quantum yield, and also shows excellent biocompatibility and remarkable liposome targeting property at the same time. Moreover, the preparation method of the boron-coordinated salicylazone double-state emission fluorophore adopts a one-pot two-step method, is simple and convenient, is high in yield, is green and environment-friendly, and has a wide application prospect.