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140 results about "ASTRAGALUS EXTRACT" patented technology

Nano-scale repairing composition, nano-scale repairing cosmetic and preparation method and application of nano-scale repairing composition and nano-scale repairing cosmetic

The invention relates to the technical field of cosmetics, in particular to a nanoscale repair composition, a nanoscale repair cosmetic and a preparation method and application of the nanoscale repair composition and the nanoscale repair cosmetic. The invention discloses a nanoscale repairing composition. The traditional Chinese medicine composition is prepared from the following raw material components in parts by weight: 4 to 6 parts of herba centellae extract, 2 to 4 parts of chamomile extract, 2 to 4 parts of radix ginseng extract, 1 to 3 parts of rhizoma curcumae longae extract, 3 to 5 parts of aloe extract, 1 to 3 parts of oat extract, 1 to 2 parts of liquorice root extract, 0.3 to 0.7 part of green tea extract, 0.5 to 1.5 parts of radix salviae miltiorrhizae extract, 0.5 to 1.5 parts of radix angelicae sinensis extract and 0.5 to 1.5 parts of ganoderma atrum extract. , 0.5 to 1.5 parts of radix astragali seu hedysari extract, 0.3 to 0.7 part of rhizoma polygoni cuspidati extract, and 0.3 to 0.7 part of onion extract. The nanoscale repairing composition and the nanoscale repairing cosmetic disclosed by the invention can improve the moisture content of skin, reduce moisture loss and redness of the skin, accelerate healing of injured skin, effectively relieve inflammatory response and promote collagen regeneration of the skin.
Owner:GUANGDONG PHARMA UNIV

Injectable temperature-sensitive hydrogel loaded with traditional Chinese medicine active exosome

The invention relates to injectable temperature-sensitive hydrogel loaded with traditional Chinese medicine active exosomes, and belongs to the technical field of clinical treatment of diabetic foot refractory wounds, and the injectable temperature-sensitive hydrogel is obtained by poloxamer 407 hydrogel and a hyaluronic acid loaded composite carrier; the composite carrier body is formed by coating a traditional Chinese medicine active exosome with a coating solution; the traditional Chinese medicine active exosome is obtained by inducing adipose-derived mesenchymal stem cells with a modified astragalus extract. The injectable temperature-sensitive hydrogel is obtained by loading a composite carrier with poloxamer 407 hydrogel and hyaluronic acid, the poloxamer 407 and the hyaluronic acid quickly form a physical barrier on a wound surface after being injected, a moist healing environment is provided, and continuous and slow release of exosome and active ingredients is realized by means of the temperature-sensitive characteristic and the network structure of the poloxamer 407 and the hyaluronic acid, so that the wound healing effect is improved. And over-high local concentration or premature loss caused by sudden release of the medicine is avoided.
Owner:SHANDONG UNIV OF TRADITIONAL CHINESE MEDICINE

High-efficiency body function repairing active small molecule peptide preparation and preparation method thereof

The invention relates to the technical field of biological preparations, and discloses an efficient body function repairing active small molecule peptide preparation and a preparation method thereof.The efficient body function repairing active small molecule peptide preparation is prepared from 15-22 parts of collagen peptide, 5-9 parts of glutathione, 10-18 parts of whey protein peptide, 5-8 parts of vitamin C, 2-4 parts of vitamin E, 1-3 parts of zinc element, 5-15 parts of astragalus membranaceus extract, 3-8 parts of probiotics and 10-20 parts of a delivery carrier. The molecular weight range of the original protein peptide, the glutathione and the whey protein peptide is 500 to 2000Da. According to the invention, collagen peptide, glutathione, whey protein peptide, vitamins and other components are proportioned to realize an anti-oxidation-repair-anti-inflammatory synergistic effect, and vitamin C, vitamin E, zinc element and an astragalus extract are added to cover multi-dimensional repair of an immune system, so that comprehensive body function repair is realized.
Owner:JIUJIANG YUBIAN BIOTECHNOLOGY CO LTD

Composite plant polypeptide composition with functions of repairing pancreas and reducing blood sugar

The invention discloses a composite plant polypeptide composition with the effects of repairing pancreas and reducing blood sugar. The traditional Chinese medicine composition is prepared from the following raw materials in parts by weight: 10 to 50 parts of ginsenoside, 5 to 30 parts of radix astragali seu hedysari extract, 3 to 20 parts of radix rehmanniae polysaccharide, 2 to 15 parts of radix trichosanthis alkaloid, 5 to 25 parts of rhizoma dioscoreae polysaccharide, 5 to 30 parts of bitter gourd polypeptide, 3 to 20 parts of folium mori alkaloid, 8 to 40 parts of rhizoma polygonati polysaccharide, 5 to 25 parts of fructus hippophae flavone, 10 to 35 parts of wheat germ peptide, 2 to 15 parts of coptis berberine, 10 to 45 parts of corn stigma polysaccharide and 3 to 20 parts of saussurea involucrata polyphenol. 1-10 parts of sophora flavescens total alkaloids, 5-25 parts of a dendrobium extract, 5-30 parts of a radix puerariae extract, 8-35 parts of L-arabinose and 10-40 parts of small molecule peptides; 20 to 100 parts of collagen peptide and 15 to 80 parts of albumin peptide; 5-50 parts of microcrystalline cellulose, 3-30 parts of fructo-oligosaccharide and 0.5-5 parts of magnesium stearate; the limitation of single sugar control or simple component mixing in the prior art is broken through, a synergistic system of plant active components and functional polypeptides is constructed, and the purity and retention rate of the plant active components are improved by optimizing the extraction process.
Owner:孟云富

Process for preparing intestinal conditioning prebiotics from clostridium butyricum and radix astragali

The invention relates to the technical field of probiotic preparations, in particular to a process for preparing intestinal conditioning prebiotics from clostridium butyricum and radix astragali seu hedysari, which comprises the following steps: (1) multi-stage synergistic activation of clostridium butyricum; (2) carrying out composite enzymolysis on the astragalus extract; (3) symbiotic fermentation; (4) performing multi-layer embedding; the prepared prebiotics have a multi-dimensional intestine regulating mechanism, the bacteriostasis and mucous membrane repairing functions of the clostridium butyricum cooperate with the prebiotics effect and antioxidant activity of the astragalus polysaccharide to form a multi-protection system, and the intestinal flora imbalance is more effectively improved compared with single probiotics or prebiotics. The multi-layer embedding technology solves the problems of gastric acid inactivation and difficulty in intestinal colonization of probiotics, and spore induction of three-stage fermentation is matched, so that the viable count maintenance rate of the product is kept at a relatively high level after the product is stored for 6 months at normal temperature, and the shelf life is remarkably prolonged.
Owner:FOSHAN SHUNDE HUOBAOYUAN BIOTECHNOLOGY CO LTD

Cassia obtusifolia antibacterial liquid for eyes and preparation method of cassia obtusifolia antibacterial liquid

PendingCN120437230AOrganic active ingredientsSenses disorderEscherichia coliChlorhexidine Acetate
The invention discloses a cassia seed antibacterial liquid for eyes and a preparation method thereof. The semen cassiae antibacterial liquid for the eyes is prepared from the following components in percentage by mass: 2.0 to 3.0 percent of semen cassiae extract, 2.0 to 3.0 percent of magnolia flower leaf extract, 2.0 to 3.0 percent of flos chrysanthemi indici extract, 2.0 to 3.0 percent of radix gentianae extract, 2.0 to 3.0 percent of flos eriocauli extract, 1.0 to 2.0 percent of radix ginseng extract, 2.0 to 3.0 percent of rhizoma polygonati extract, 1.0 to 2.0 percent of radix codonopsis extract and the balance of water. The traditional Chinese medicine composition has the beneficial effects that various eyesight-improving traditional Chinese medicine components are adopted, the traditional Chinese medicine composition does not contain any artificial hormone and antibiotic, has no toxic or side effect, has the effects of clearing liver and improving eyesight, resisting bacteria and inflammation, and improving retina microcirculation and blood flow volume, and is matched with chlorhexidine acetate, so that the traditional Chinese medicine composition has the effects of clearing liver and improving eyesight, resisting bacteria and inflammation, and improving retina microcirculation and blood flow volume. The eye drops have the advantages that the eye drops have strong inhibition effects on candida albicans, escherichia coli and staphylococcus aureus, the components of the eye drops do not contain any irritant component, irritation influence on eyes is avoided, the preparation method is simple, and the eye drops can be easily applied to large-scale production and processing processes.
Owner:TIANJIN QIANFANG CONSULTING BIOTECHNOLOGY CO LTD

Codonopsis pilosula and ginseng peptide collagen drink capable of consolidating basis, reinforcing vital essence and resisting aging as well as preparation method and application of codonopsis pilosula and ginseng peptide collagen drink

The invention provides a ginseng and ginseng peptide collagen drink for consolidating basis, reinforcing vital essence and resisting aging as well as a preparation method and application thereof, relates to the technical field of health-care drinks, and belongs to the IPC classification number A23L2. The ginseng and ginseng peptide collagen drink comprises a ginseng extract, a protein peptide compound, a tremella extract, a Chinese wolfberry fruit extract, an astragalus membranaceus extract, fruit and vegetable enzymes, kale powder and PQQ disodium salt. The protein peptide compound is composed of sea cucumber peptide, bone collagen peptide, ovalbumin peptide, fish scale peptide and cubilose peptide. The ginseng extract and the astragalus extract can tonify qi and blood, the wolfberry extract and the tremella extract can nourish yin, and the sea cucumber peptide and the fish scale peptide can tonify kidney, tonify qi, blood, yin and yang and consolidate basis; the protein peptide compound supplements collagen and amino acid required by a human body and delays structural aging; the PQQ disodium salt can reverse mitochondrial aging, and the fruit and vegetable enzyme and the kale powder can regulate metabolic balance. Animal experiments show that the double-ginseng peptide collagen drink has the effects of resisting oxidation, improving immunity and resisting aging.
Owner:HENAN ENCE CULTURAL COMM CO LTD

Composition for reducing uric acid and relieving gout and preparation method thereof

The invention provides a composition for reducing uric acid and relieving gout and a preparation method thereof, and relates to the technical field of products for reducing uric acid and relieving gout. The composition comprises the following raw materials: 18-24 parts of phellinus igniarius, 9-13 parts of sunflower disc small molecule peptide extract, 3-7 parts of corn stigma, 4-6 parts of poria cocos, 2-5 parts of pawpaw, 3-6 parts of liquorice, 2-5 parts of astragalus extract and 3-6 parts of lettuce extract. The preparation method of the sunflower disc small-molecule peptide extract comprises the following steps: carrying out enzymolysis on sunflower disc powder twice, carrying out membrane filtration to obtain a sunflower disc small-molecule peptide solution, reacting the sunflower disc small-molecule peptide solution with chitosan oligosaccharide and transglutaminase, and carrying out freeze drying to obtain the sunflower disc small-molecule peptide extract. Through the proper raw material composition and proportion, the metabolic function can be effectively regulated to promote excretion of uric acid, so that the content of xanthine oxidase and adenosine deaminase in the liver is obviously reduced, the uric acid level is effectively reduced, the intestinal probiotic structure can be stabilized, the immunity is enhanced, the kidney is protected, and the good effects of reducing uric acid and relieving gout are achieved.
Owner:ZHEJIANG SANGZHIYUAN TRADITIONAL CHINESE MEDICINE TECHNOLOGY CO LTD

Compound fermentation composition for regulating immunity and intestinal microecology as well as preparation method and application of compound fermentation composition

The invention belongs to the technical field of functional food, and particularly relates to a compound fermentation composition for regulating immunity and intestinal microecology as well as a preparation method and application of the compound fermentation composition. The invention provides a compound fermentation composition for regulating immunity and intestinal microecology. Comprising the following components: blueberry freeze-dried powder, an astragalus extract, a lycium ruthenicum extract, a day lily flower extract, grifola frondosa polysaccharide, schizochytrium limacinum powder, a red yeast rice extract, polygonatum polysaccharide, cordyceps militaris, xylooligosaccharide, yeast beta-glucan, lactoferrin, stevioside, a complex microbial inoculant and a complex enzyme. According to the compound fermentation composition disclosed by the invention, high-efficiency immunoregulation, long-acting intestinal balance and maximum component utilization are realized, and an efficient, stable and applicable solution is provided for regulating immunity and intestinal microecology.
Owner:CHONGQING WANYUANJIA PHARM CO LTD

A granule of anti-liver cancer special medical food based on multi-target point synergy and a preparation method thereof

PendingCN122271519AImprove bioavailabilityInhibit apoptosisBiotechnologyNutrition
This invention discloses a multi-target synergistic anti-liver cancer medical food granule and its preparation method. The granule uses medicinal and edible homologous foods and novel resource foods as raw materials, and is composed of curcumin extract, esterified fat-soluble EGCG, Moringa leaf powder, yeast β-glucan, Astragalus extract, Schisandra extract, Salvia miltiorrhiza extract, Poria cocos powder, resistant dextrin, and erythritol in a specific ratio to construct a three-dimensional synergistic system of "direct killing-immune regulation-liver protection," which can induce ferroptosis in liver cancer cells, inhibit protective autophagy, activate the body's immunity, and protect liver cells. This invention employs directional extraction, multi-layer coating, and high-pressure fusion granulation technology. Nanoparticle liposome encapsulation, esterification modification, and pH-responsive enteric coating improve the stability and bioavailability of the components, solving the problems of poor water solubility, low absorption, and easy degradation of natural active ingredients. The granule has clear efficacy, high safety, and stable process, and can be used as a medical food for adjuvant therapy and nutritional support during the recovery period of liver cancer.
Owner:YUNNAN HUANGJIA MEDICAL CIRCLE INST OF TRADITIONAL CHINESE MEDICINE

Efficient water locking and repairing mask and preparation method thereof

The invention discloses an efficient water-locking repair mask and a preparation method thereof, and belongs to the technical field of cosmetics, the efficient water-locking repair mask comprises the following components by mass: 0.5-2.0% of an astragalus membranacus extract fermentation broth, 0.1-0.5% of ceramide NP, 0.05-0.3% of a sodium hyaluronate composition, 0.1-0.3% of polyquaternium-51, 1-3% of a lactobacillus plantarum fermentation lysate, 1-5% of ethanol, and the balance of deionized water. The lactobacillus plantarum fermentation lysate comprises propionic acid and butyric acid. The Astragalus membranacus extract fermentation broth can remove allergic components and form a lipid-polysaccharide interpenetrating network with ceramide NP, and the Astragalus membranacus extract fermentation broth and ceramide NP synergistically simulate a natural barrier structure of skin, so that the order degree of cuticle lipid is improved, transdermal moisture loss is prevented, and the repairing and water locking functions are remarkably enhanced; butyric acid and propionic acid in the lactobacillus plantarum fermentation lysate promote penetration of ceramide NP by acidifying a cuticle microenvironment (pH 4.5), and the biological safety is high.
Owner:东方宏业(山东)生物科技有限公司

A traditional Chinese medicine composition for promoting wound healing and a preparation method thereof

The present application relates to the technical field of wound repair, and provides a traditional Chinese medicine composition for promoting wound healing and a preparation method thereof.The traditional Chinese medicine composition comprises a first traditional Chinese medicine composition and a second traditional Chinese medicine composition which are applied to the acute phase and the repair proliferation phase.The former comprises naked flower purple perilla extract, nectarine leaf extract, purple perilla extract, dragon's blood micro powder, spironast extract, centella asiatica volatile oil, rhubarb extract, borneol, mussel mucin, medicinal glycerol and purified water.The latter comprises red algae extract, nectarine leaf extract, radix astragali extract, panax notoginseng total saponins, aloe extract, dendrobium officinale extract, sea buckthorn extract, pinctada martensii purified peptide, snail glycosaminoglycan, medicinal glycerol and purified water.The composition can play the roles of antibiosis, anti-inflammation, hemostasis, analgesia and astringency in the acute phase, and can promote angiogenesis, collagen synthesis and epithelial regeneration in the repair proliferation phase, so that the wound is rapidly repaired and healed.
Owner:江苏亨瑞生物医药科技有限公司 +1

Preparation process of astragalus polysaccharide powder

The application relates to the field of astragalus extract technology, in particular to a preparation process of astragalus polysaccharide powder. The preparation process of the astragalus polysaccharide powder comprises the following steps: soaking astragalus medicinal materials in a soaking liquid, heating to extract astragalus polysaccharide and astragalus glycoside, separating liquid phase, concentrating the liquid phase to obtain concentrated liquid, adding a biological wrapping agent, spray drying, and obtaining astragalus polysaccharide powder; the soaking liquid comprises a co-crystal solvent and water; the biological wrapping agent can wrap the astragalus polysaccharide and the astragalus glycoside. The co-crystal solvent changes the crystal structure of the astragalus polysaccharide and the astragalus glycoside through non-covalent interaction, improves the solubility of the astragalus polysaccharide and the astragalus glycoside, and the soaking liquid heating extraction can significantly improve the extraction rate of the astragalus polysaccharide and the astragalus glycoside compared with pure water heating extraction. The biological wrapping agent is a substance that can be eaten by livestock and poultry.
Owner:山东益远药业有限公司

Cistanche peptide composition and application thereof

The invention discloses a cistanche peptide composition, which is prepared from the following components in percentage by mass: 15 to 20 percent of cistanche peptide, 10 to 20 percent of brilliant bugleweed herb extract and 8 to 15 percent of radix astragali seu hedysari extract. The invention also provides a process for preparing the cistanche peptide and the cistanche peptide composition, and a traditional Chinese medicine composition containing the cistanche peptide composition. The cistanche peptide composition can be used for preventing or treating neurodegenerative diseases.
Owner:SHOUYAO (JIANGSU) BIOTECHNOLOGY CO LTD

Rosin extract composition, method of preparation and use

The present application relates to the technical field of medical preparation, and discloses a Russian olive leaf extract composition, a preparation method and application. The composition comprises the following components in parts by weight: 10-20 parts of Russian olive leaf extract derivative, 10-15 parts of bitter gourd extract, 10-15 parts of pueraria extract, 5-10 parts of hawthorn extract and 5-10 parts of astragalus extract. The present application also provides a preparation method. Compared with the prior art, the Russian olive leaf extract composition prepared by the present application has the effects of reducing blood sugar, blood lipid and blood pressure, and is stable in drug efficacy, mild and safe.
Owner:LUHUO XUEYU RUSSIAN COLOR CO LTD

Compositions for removing dampness, controlling blood sugar, balancing blood pressure, and regulating blood lipids, and their applications.

PendingCN122296456ABiotechnologyMedicinal herbs
This invention relates to the field of health products or food technology, and more specifically to a composition and its application in removing dampness and controlling blood sugar, balancing blood pressure, and regulating blood lipids. The invention provides a composition for removing dampness and controlling blood sugar, balancing blood pressure, and regulating blood lipids, comprising Poria cocos extract, Astragalus membranaceus extract, hirudin, and at least one or more of Eucommia ulmoides extract, Gynostemma pentaphyllum extract, and Morus alba twig extract. The composition provided by this invention utilizes extracts from at least four precious Chinese medicinal herbs to exert a synergistic effect, jointly achieving the effects of lowering blood pressure, removing dampness and lowering blood sugar, and lowering blood lipids.
Owner:SHANGHAI DINGYA PHARM CHEM CO LTD

A composition for resisting PRRSv and improving sow reproductive performance and its application

ActiveCN119524054BImprove reproductive performanceImprove physiological and biochemical indicatorsFood processingAntiviralsBiotechnologyLeonurus japonicus
The present application relates to the field of traditional Chinese medicinal materials, in particular to a composition for resisting PRRSv and improving the reproductive performance of sows and application thereof. The present application formulates a composition composed of 10 plant extracts (Angelica sinensis extract, Atractylodes macrocephala Koidz extract, Glycyrrhiza uralensis Fisch extract, Eucommia ulmoides Oliver extract, Eucommia ulmoides leaf extract, Populus davidiana Dode extract, Perilla frutescens leaf extract, Gynostemma pentaphyllum Makino extract, Leonurus japonicus extract and Astragalus membranaceus Bge extract) for sows in late pregnancy, and collects sow blood and placenta samples at the time of delivery, studies the influence of the composition on sow reproduction, and explores the mechanism of action. The experimental results show that the composition can improve the reproductive performance of sows by increasing the total number of piglets and other indicators; meanwhile, the composition can effectively inhibit the replication of PRRSv.
Owner:GUANGDONG OCEAN UNIVERSITY

Jinzhuling peptide drink and preparation method thereof

The present invention discloses a rosa roxburghii tratt fruit peptide drink and a preparation method thereof, and relates to the technical field of nutritional health drink processing, and the rosa roxburghii tratt fruit peptide drink consists of the following raw materials in parts by mass: 100 parts of rosa roxburghii tratt fruit juice, 1.5-2.5 parts of a lucid ganoderma extract, 0.8-1.2 parts of a radix astragali seu hedysari extract, 4.5-7.5 parts of a coix seed extract, 8-12 parts of giant salamander peptide, 4.0-6.5 parts of locust bean gum, 0.03-0.05 part of stevioside and 60-100 parts of water. According to the rosa roxburghii tratt peptide beverage and the preparation method thereof, the rosa roxburghii tratt is scientifically compounded with various medicinal and edible substances and nutritional ingredients such as the lucid ganoderma, the astragalus membranaceus, the coix seeds and the giant salamander peptide for the first time, and a nutrition complementary composite system is formed. The compounding of lucid ganoderma and roxburgh rose has a scientific basis supported by literatures.
Owner:VIDAL HEALTH IND (GUIZHOU) CO LTD

Herbal beverage formula and preparation method

The invention discloses a herbal beverage formula which comprises the following components: a natural raw material extract compound group and a bioactive factor group, the natural raw material extract compound group consists of a spina date seed extract, an astragalus extract, a red date extract, a lily extract, a longan extract, a poria cocos extract, a lotus seed extract, a liquorice extract, a mulberry extract, a rhizoma polygonati extract, a fingered citron extract, oyster powder, a Chinese yam extract, a pericarpium citri reticulatae extract and a stevia rebaudiana extract; the bioactive factor group comprises aminobutyric acid and phosphatidylserine, and the mass ratio of jujuboside A in the spina date seed extract to the aminobutyric acid is 1: (0.025-0.035). The method has the advantage that the gradient temperature control segmented extraction method is creatively designed. The retention rate of the target extract is remarkably improved, and sufficient release of macromolecular active substances such as polysaccharide is ensured. And a high-pressure homogeneous nano-emulsification technology is adopted, so that the problems of floating oil, flocculation and layering which are easy to occur in the traditional emulsion are avoided.
Owner:SHANXI CONGPAI BEVERAGE CO LTD

A kitten food without palatability enhancers and its preparation method

This invention discloses a kitten food without palatability enhancers and its preparation method, relating to the field of pet food technology. It comprises the following components: polypeptide chicken meal, soy protein peptides, gluten hydrolysate, lactoferrin, astragalus extract, yam powder, rosemary oil, resveratrol, tributyrate, and rice. By adding substances containing small peptides and plant extracts to the kitten food, this invention provides the body with a large amount of high-quality animal protein without adding any chemically synthesized palatability enhancers, preservatives, or other chemical additives. This effectively promotes the body's decomposition and metabolism of nutrients, promotes the growth of kittens, and also enhances the body's antioxidant capacity and reduces the occurrence of diarrhea.
Owner:GRAD (FUJIAN) BIOTECHNOLOGY CO LTD

A traditional Chinese medicine composition with the functions of improving immunity and tonifying qi and anti-aging and application thereof

The application provides a traditional Chinese medicine composition with the functions of improving immunity and tonifying qi and resisting aging and application thereof. The traditional Chinese medicine composition comprises the following components in mass fractions: green tea 2255 parts, Gynostemma pentaphyllum 1000 parts, Astragalus extract 625 parts, Lycium barbarum fruit extract 600 parts, Ligustrum lucidum fruit extract 420 parts and Ganoderma lucidum extract 100 parts. The traditional Chinese medicine composition has the functions of improving immunity and tonifying qi and resisting aging through the synergistic effect of the multiple components.
Owner:GUANGZHOU TIANCHEN YIPIN TECH CO LTD

Sugar-controlling composition containing rhodiola rosea extract, preparation method of sugar-controlling composition and application of sugar-controlling composition in health-care products

The invention relates to a sugar-controlling composition containing a rhodiola rosea extract, a preparation method of the sugar-controlling composition and application of the sugar-controlling composition in health-care products, and relates to the technical field of functional foods. The sugar control composition containing the rhodiola rosea extract is prepared from the following components in parts by weight: 5 to 15 parts of rhodiola rosea extract, 10 to 20 parts of radix astragali seu hedysari extract, 5 to 15 parts of bitter gourd extract, 3 to 10 parts of cortex cinnamomi extract, 3 to 8 parts of folium mori extract, 2 to 8 parts of rhizoma coptidis extract, 2 to 5 parts of grape seed extract, 20 to 40 parts of rhizoma dioscoreae powder and 8 to 15 parts of adhesive. The rhodiola rosea extract is taken as a core, the radix astragali extract, the bitter gourd extract, the cortex cinnamomi extract, the folium mori extract, the rhizoma coptidis extract, the grape seed extract, the Chinese yam powder and the adhesive are compounded, a synergistic sugar control system is constructed, full-chain intervention on blood glucose metabolism is realized, and the components in the formula are medicinal and edible or natural extracts, so that the safety is high, and the effect is good. The long-term conditioning requirements are met.
Owner:NINGBO OSAKI BIOTECH CO LTD

Sanguisorba officinalis extract with post-sunburn repairing function and preparation method thereof

The invention discloses a sanguisorba officinalis extract with a post-sunburn repairing function and a preparation method thereof. The sanguisorba officinalis extract is prepared from a sanguisorba officinalis extract, a piper nigrum extract, an oat extract, ceramide, a grape seed extract, a bluestone lotus extract, a honeysuckle flower extract, an astragalus membranaceus extract and a radix sophorae flavescentis extract. The traditional Chinese medicine composition comprises the following components in parts by weight: 50-80 parts of sanguisorba officinalis extract; 3-5 parts of a piper nigrum extract; 2-4 parts of an oat extract; 1 to 3 parts of ceramide; and 1-2 parts of a grape seed extract. The traditional Chinese medicine composition is prepared from the sanguisorba officinalis extract, the grape seed extract, the bluestone lotus extract, the honeysuckle flower extract, the astragalus membranaceus extract and the radix sophorae flavescentis extract, can effectively improve the repair effect on sunburnt skin, is integrally prepared from pure traditional Chinese medicines, does not contain any chemical component, and is beneficial to the body health of people.
Owner:SHENZHEN XINGLIAO NETWORK TECHNOLOGY CO LTD

Culture medium and culture method for preparing umbilical cord mesenchymal stem cell exosome

The invention discloses a culture medium and a culture method for preparing umbilical cord mesenchymal stem cell exosomes. The culture medium for preparing the umbilical cord mesenchymal stem cell exosome is prepared from 99.79 to 99.99 weight percent of a mesenchymal stem cell serum-free culture medium and 0.01 to 0.21 weight percent of an additive, the additive is a cyclodextrin modified radix astragali seu hedysari extract; the cyclodextrin modified astragalus membranaceus extract is obtained by reacting organic acid modified cyclodextrin with an astragalus membranaceus extract. The invention also provides a preparation method of the composition. Compared with the prior art, the culture medium for preparing the umbilical cord mesenchymal stem cell exosome has the advantages that the culture medium stability is good, proliferation of mesenchymal stem cells can be promoted, and human umbilical cord mesenchymal stem cells are effectively induced to synthesize a large amount and secrete exosome.
Owner:SHENZHEN AOKAI BIOTECHNOLOGY CO LTD

NK cell in-vitro efficient culture system and application

The invention provides an NK cell in-vitro efficient culture system and application, the culture system comprises a K562 engineering cell, and six proteins of IL21, IL12, IL15, CD40L, CD155 and CD112 are expressed on a cell membrane of the K562 engineering cell in a transmembrane mode; the NK cell culture composition comprises the following components: a liquid serum-free cell culture medium, 1-5% (v / v) of autologous plasma, 100-250 [mu] g / ml of an astragalus extract and 200-500 [mu] g / ml of an angelica sinensis extract, and the dosage ratio of the astragalus extract to the angelica sinensis extract is 1: 2. The NK cell with high amplification multiple, high purity and high lethality can be obtained by a culture system established by taking the K562 engineering cell constructed by the invention as a trophoblast cell, taking an astragalus extract and an angelica sinensis extract as culture additives and taking PBMC as an original culture material, and the culture system has important significance for treating cancers by cell drugs.
Owner:QINGDAO RESTORE BIOTECHNOLOGY CO LTD +1

A method for drying Astragalus extract

ActiveCN116459536BBiotechnologyCyclodextrin
This invention relates to the field of Astragalus processing technology and discloses a method for drying Astragalus extract. The method involves adding a drying dispersant to the Astragalus extract and then spray drying it. The drying dispersant is β-cyclodextrin or the residue after Astragalus extraction. In this invention, spray drying is used to dry the Astragalus aqueous extract, and a dispersant (β-cyclodextrin or residue) is added to the system to be dried. Practical verification shows that the inlet air temperature can be controlled at around 130℃, which improves drying efficiency. Furthermore, the yield after drying, based on the calculated solids content, can reach over 95%.
Owner:LONGXI CHEEZHENG MEDICINAL MATERIALS CO LTD

Exosome composition containing resveratrol, astragalus membranaceus and ginseng as well as preparation method and application of exosome composition

PendingCN121971506AAnti-fibrotic activity inhibitionInhibition of fibrotic activityHydroxy compound active ingredientsArtificial cell constructsGINSENG EXTRACTBULK ACTIVE INGREDIENT
The invention discloses an exosome composition containing resveratrol, astragalus membranaceus and ginseng as well as a preparation method and application of the exosome composition, and belongs to the technical field of biological medicines. The exosome composition disclosed by the invention is obtained by inducing alveolar epithelial cells by active ingredients containing resveratrol, an astragalus extract and a ginseng extract and then secreting the alveolar epithelial cells. The preparation method of the exosome composition mainly comprises the following steps: co-culturing the active component and alveolar epithelial cells, and then sequentially carrying out differential centrifugation and ultracentrifugation on the collected cell supernatant to purify the exosome. The invention also provides a pharmaceutical preparation containing the exosome composition. According to the composition, traditional Chinese medicine active ingredients are combined with a modern cell exosome technology, a potential strategy is provided for prevention and treatment of pulmonary fibrosis, and the composition has a good application prospect.
Owner:北京圣美细胞生命科学工程研究院有限公司

Preparation method of astragalus mongholicus extracting solution with high antioxidant activity and extracting solution

The invention discloses a preparation method of a radix astragali extracting solution with high antioxidant activity and the extracting solution, and aims to solve the problems of low extraction rate of active substances and inaccurate detection of antioxidant activity in the prior art. According to the method, five factors including ethanol content, extracting solution multiple and the like are taken as key variables, U10 * (108) uniform test design is adopted, the DPPH free radical scavenging rate is accurately determined by combining an electron paramagnetic resonance technology, and the contents of astragaloside, general flavone and polysaccharide are synchronously detected. A quantitative model is established through multivariate linear regression analysis, and the optimal process parameters are determined: the ethanol content is 80%, the extracting solution multiple is 4, the temperature is 85 DEG C, the time is 1.5 h, and the extraction time is 1 time. The DPPH free radical scavenging rate of the extracting solution prepared through the technology is larger than or equal to 92.75%, polysaccharide is larger than or equal to 12520 mg / L, total flavone is larger than or equal to 323.77 mg / L, astragaloside is larger than or equal to 257 mg / L, synergistic efficient extraction of multiple components is achieved, and the extracting solution is suitable for industrial production.
Owner:JING BRAND

A composite traditional Chinese medicine and application thereof to preparation of a medicine for preventing and treating postoperative gastrointestinal dysfunction

The application belongs to the technical field of traditional Chinese medicines, and provides a compound traditional Chinese medicine and application thereof in preparation of a medicine for preventing and treating postoperative gastrointestinal dysfunction. The compound traditional Chinese medicine is composed of radix codonopsis extract, radix bupleuri extract, fructus aurantii extract, radix astragali extract and radix angelicae extract with a mass ratio of 1:3-4:1-2:3-5:2-3. Animal experiments show that the compound traditional Chinese medicine can significantly reverse the decrease of postoperative gastrointestinal motility function, reverse the changes of gastrointestinal hormones VIP and MTL, and help and promote the recovery of postoperative gastrointestinal motility function. The compound traditional Chinese medicine has reasonable formula, is convenient to use, and has a wide application range, and has curative effects on the recovery of postoperative gastrointestinal function caused by various conditions.
Owner:ZHEJIANG HOSPITAL