The invention discloses a compound anti-
cancer Chinese patent medicine based on multi-target synergism and a preparation method thereof, and relates to the technical field of
traditional Chinese medicine compound anti-tumor, the compound is composed of
panax notoginseng saponins, ornithogalum caudatum
saponin, lance asiabell root
polysaccharide, sculellaria barbata flavone,
oldenlandia diffusa
polysaccharide, zedoary
turmeric oil and
ganoderma triterpenes according to a specific proportion. Wherein the monarch
drug accounts for 30%-40% of cooked
panax notoginseng saponins, the ministerial
drug accounts for 20%-35% of ornithogalum caudatum
saponin, the ministerial
drug accounts for 5%-10% of the radix astragali extract, the
adjuvant drugs account for 10%-15% of the
adjuvant drugs and the conductant drugs account for 5%-10% of the conductant drugs, the nano-
liposome co-loading technology is adopted, fat-soluble components are loaded on a
liposome hydrophobic layer, water-soluble components are loaded on a hydrophilic layer, the preparation effect that the encapsulation efficiency is larger than or equal to 95%, and the particle size is 80 + / -5 nm is achieved, and the preparation effect is good.
Trehalose is added as a freeze-
drying protective agent, so that the stability reaches 36 months, and the freeze-dried
powder can be used for
solid tumor treatment and postoperative recurrence prevention, is especially suitable for
chemotherapy of drug-resistant tumors, and widens the application range of anti-tumor traditional Chinese medicines.