113 results about "Pediococcus acidilactici" patented technology

The invention belongs to the field of microorganisms. The invention provides a compound strain, a microbial inoculum and application of the compound strain in preparation of fermented East purple perilla tea. The compound strain comprises phytobacterium plantarum 2HDS3-La5 with the preservation number of CGMCC NO.34339, pediococcus acidilactici 2HDS3-SM6 with the preservation number of CGMCC NO.34337, Witzmania clostridium N2-La1 with the preservation number of CGMCC NO.34338, and the microbial inoculum is applied to preparation of fermented East purple perilla tea. The invention also provides application of the compound strain or a microbial inoculum containing the compound strain in preparation of fermented East purple perilla tea. The compound strain disclosed by the invention is applied to preparation of the fermented Dongbao tea, the content of substances with anti-inflammatory, anti-oxidation and immunoregulation effects in the Dongbao tea is remarkably increased by multiple times, and the prepared fermented Dongbao tea can remarkably improve the cell activity.

The invention relates to the technical field of microbiology and food processing, in particular to pediococcus acidilactici and application of the pediococcus acidilactici in preparation of a brain-intestinal axis regulating efficacy metagen product.The high-activity pediococcus acidilactici DY-1 is separated out from natural fermentation pickles of super-polyselenium plant cardamine violifolia for the first time; the strain can be widely applied to fermentation of high-selenium plant-based food, can significantly promote glycolysis release of selenium-containing active substances, has good acid resistance, high protease activity and high lipase activity, can fully ferment plant-based fermentation raw materials, and has high yield. Glycolysis of macromolecular substances such as protein, saccharides and fat is facilitated, accumulation of active ingredients such as essential amino acid, unsaturated fatty acid, alkaloid and phenolic substances is promoted, and the edibility and functionality of the product are improved; and the organic selenium-rich metagen product prepared by sterilizing the fermentation mixture can synergistically improve human body cognition and emotion regulation regulated by microorganism-intestinal-brain axis.

The invention discloses pediococcus acidilactici TH903 and application thereof in directional preparation of rare ginsenoside Rg4 by fermenting ginseng berries, and belongs to the field of fermentation engineering, the pediococcus acidilactici TH903 is preserved in the China Center for Type Culture Collection on September 29, 2025, the preservation number is CCTCC NO: M20252155, and the preservation unit is the China Center for Type Culture Collection. The Pediococcus acidilactici TH903 is utilized to successfully and directionally convert ginsenoside Re in the ginseng berry extract into rare ginsenoside Rg4, the rare ginsenoside Rg4 is mainly used as a fermentation product, the main target product, namely the rare ginsenoside Rg4, is accurately prepared, and the Pediococcus acidilactici TH903 has relatively high specificity, and can be used for preparing the rare ginsenoside Rg4. Meanwhile, the method has the advantages of high conversion efficiency and high conversion product content, and a cheap and efficient preparation process is established for the rare ginsenoside Rg4.

The invention discloses a microbial odor remover suitable for environment and a preparation method thereof, and relates to the technical field of daily chemical products. The preparation method comprises the following steps: adding pediococcus acidilactici and bacillus velezensis into a citric acid-disodium hydrogen phosphate buffer solution according to a ratio, standing and activating, adding bromelain, lipase, rosmarinic acid nanoemulsion, tea polyphenol and citrus polyphenol-EDTA (Ethylene Diamine Tetraacetic Acid) mixture, homogenizing, adding konjac glucomannan-chitosan gel and a trehalose-glycerol compound according to a ratio, stirring, filtering, and drying to obtain a finished product. And subpackaging in a dark place to prepare the microbial odor remover suitable for the environment. Through the synergistic effect of microorganisms, enzymes and a natural deodorization medium, a multi-stage peculiar smell elimination system is constructed, the dual functions of immediate neutralization and continuous bacteriostasis are achieved, the application scene is wide, corrosion and residues to base materials such as fabric and plastic are avoided, and the concentration of harmful gas can be more effectively controlled and pathogenic microorganisms can be inhibited in large-scale breeding application.

The invention relates to pediococcus acidilactici, in particular to pediococcus acidilactici TCI550 with the preservation number of DSM34536, and the pediococcus acidilactici TCI550 has the preservation number of DSM34536. In addition, the pediococcus acidilactici TCI550 and / or metabolites thereof can be suitable for preparing a composition for nerve health care and / or cognition improvement.

The present invention relates to a composition for alleviating obesity, improving cognitive function and memory, and preventing Alzheimer's disease, comprising a fermented hemp seed product as an active ingredient. The fermented hemp seed product prepared by inoculating a Pediococcus acidilactici OHSI1 strain (deposit number: KCTC 15831BP) strain, of the present invention, has the effects of: increasing the abundance and diversity of intestinal microorganisms; increasing beneficial intestinal bacteria; reducing harmful intestinal bacteria; alleviating intestinal microbial flora imbalance; anti-obesity; antioxidation; and controlling Alzheimer's disease-associated enzyme activity, and thus can be effectively used as a food composition or a pharmaceutical composition for preventing, alleviating, or treating obesity or cognitive dysfunction, and as a health functional food composition for improving memory and cognitive function by improving intestinal microbial flora.

The invention relates to selenium-enriched pediococcus acidilactici Se34 with anti-oxidation, cholesterol-lowering and anti-tumor effects and application of the selenium-enriched pediococcus acidilactici Se34. The pediococcus acidilactici Se34 is preserved in the China General Microbiological Culture Collection Center (CGMCC), the preservation number of the pediococcus acidilactici Se34 is CGMCC No.33933, and the preservation date of the pediococcus acidilactici Se34 is March 24, 2025. The pediococcus acidilactici Se34 provided by the invention integrates excellent probiotic characteristics (acid-resistant bile salt, safe and colonizable), efficient selenium enrichment capacity and remarkably enhanced activity of resisting oxidation, reducing cholesterol and inhibiting specific cancer cell proliferation and metastasis after selenium enrichment. The strain and the selenium-rich product thereof have important application value in the fields of developing functional foods (selenium-rich probiotic products), antioxidant / cholesterol-reducing health-care foods, potential auxiliary anticancer biological preparations or prodrugs and the like.

The invention belongs to the technical field of microorganisms, and particularly relates to pediococcus acidilactici 32 and application thereof. The invention relates to pediococcus acidilactici 32, which is preserved in the China Center for Type Culture Collection on July 28, 2025, and the preservation number of the pediococcus acidilactici 32 is CCTCC (China Center for Type Culture Collection) NO: M20251721. The strain has extremely high acid resistance, and the survival rate is still 70.30% after the strain is treated for 2 hours under the extreme acid condition of pH 2 and is far higher than that of an existing strain; excellent cholate tolerance: the survival rate can still reach 92.30% after being treated in 0.3% cholate for 3 hours, so that the colonization ability of the strain in intestinal tracts is remarkably improved; the broad-spectrum antibacterial effect is achieved, the obvious inhibiting effect on various pathogenic bacteria is achieved, and the diameter of an inhibition zone is larger than or equal to 18 mm.

The present invention relates to a food composition for improving obesity or cognitive function, comprising a hemp seed fermentate prepared using the Pediococcus acidilactici SRCM201591 strain. The fermentate was confirmed for radical scavenging ability, ROS scavenging ability, and AChE inhibitory ability, and found to have an antioxidant effect as a high content of polyphenol was measured. An anti-obesity effect was also confirmed through assays for triglyceride inhibition and C. elegans size reduction, and antioxidant and anti-obesity related gene regulation effects were identified following administration of the fermented extract. Accordingly, the fermentate can be advantageously used in the manufacture of food for improving obesity or cognitive function.

The invention discloses pediococcus acidilactici and application thereof in preparation of a medicine for preventing or treating diarrhea of yak calves, and belongs to the technical field of microorganisms. The pediococcus acidilactici is preserved in the China Center for Type Culture Collection, the preservation number is CCTCC NO: M20252012, and the preservation date is September 12, 2025. The strain has remarkable bacteriostatic activity on yak-derived multi-drug-resistant escherichia coli (the accession number of NCBI is PP859186). After the probiotic preparation is orally taken, the yak calf diarrhea induced by escherichia coli can be effectively relieved, the diarrhea rate and the inflammatory factor level are remarkably reduced, the oxidation resistance is improved, the flora structures of intestinal bacteria and fungi are adjusted, and the micro-ecological balance is restored. The invention provides a safe, green and efficient alternative antibody product which is suitable for the plateau yak breeding industry.

The application provides a pediococcus acidilactici M4 for low-moisture fermented feed and an application thereof, and belongs to the field of microbial application and feed technology. The application uses the pediococcus acidilactici M4 to prepare fermented total mixed ration. The bacteria have the characteristics of high osmosis and fast acid production, and can reduce the pH value of the fermentation system in a short time; have strong broad-spectrum bacteriostatic effect on escherichia coli, chicken white dysentery salmonella and staphylococcus aureus; and perfectly adapt to the fermentation of low-moisture total mixed ration. The strain is used as the fermentation strain of low-moisture total mixed ration, can significantly reduce the content of acid detergent fiber and neutral detergent fiber, improve the crude protein level, and then improve the digestibility of the daily ration, increase the content of probiotics such as lactic acid bacteria and yeast in the daily ration, reduce the content of pathogenic bacteria such as escherichia coli in the daily ration, and also can improve the content of volatile fatty acid in the daily ration, improve the quality of the daily ration, and improve the feeding value of the daily ration.

The present invention relates to the field of microbial technology, and provides a Pediococcus acidilactici YYS-J2 that can degrade acrylamide and produce high levels of phenyllactic acid, and its application. Pediococcus acidilactici The preservation number of YYS-J2 is CGMCC No. 28183. This *Pediococcus lactis* YYS-J2 exhibits excellent acrylamide removal capacity, high efficiency in L-phenylalanine utilization and metabolism, high-quality phenyllactic acid production capacity, and excellent *Streptococcus mutans* antibacterial activity. It also produces superoxide dismutase (SOD) and shows good tolerance in simulated gastric and intestinal fluids. This *Pediococcus lactis* YYS-J2 can provide a new probiotic source for the development of functional products such as acrylamide removal products, antibacterial products, and SOD-producing products, and has significant application value.

The microorganism strain Pediococcus acidilactici TAK 589 CoccobEst is a new antimicrobial and antioxidant probiotic, CoccobEst inhibits the growth of the enteropathogens L. monocytogenes, E. coli, S. enteritidis, S. typhimurium, S. sonnei, S. aureus, E. faecalis and C. sakazakii, but does not inhibit lactobacilli of natural intestinal microbiota. The strain's antimicrobial properties are enhanced by periplasmic peptidoglycan hydrolases with proteolytic activity. CoccobEst is used as a zootechnieai feed additive to prevent bacterial infections in the gastrointestinal tract of farm animals and pets and to prevent and reduce diarrhea. CoccobEst has highly active antioxidant defense system, increasing the redox activity of glutathione and reducing oxidative stress in cells. Therefore, CoccobEst is used as a food supplement or functional food for humans to prevent bacterial infections of the gastrointestinal tract and to prevent and reduce oxidative stress. In addition, CoccobEst is used as a starter culture in fermentation of vegetables.

The invention relates to pediococcus acidilactici b1274 and application thereof, and belongs to the technical field of beneficial bacterium application. The pediococcus acidilactici b1274 is preserved in the China Center for Type Culture Collection on September 24, 2025, the preservation number is CCTCC M 20252094, and the pediococcus acidilactici b1274 is obtained by separation and purification from distiller's yeast. The pediococcus acidilactici can be used for preparing microbial enhanced distiller's yeast, is applied to brewing of fen-flavor liquor, and can improve the content of ethyl acetate, ethyl lactate and total acid in the liquor and reduce the content of acetaldehyde at the same time. Compared with a production control group, the content of ethyl acetate is increased by 50.0%, the content of ethyl lactate is increased by 8.1%, the total acid is increased by 46.4%, the acetaldehyde is reduced by 48.4%, the brewed white spirit shows the style of faint scent, purity, mellowness, fullness, softness, sweetness, freshness, long aftertaste and mellow and prominent acid ester taste, and a safe and reliable functional strain and a technical scheme are provided for improving the quality of the fen-flavor white spirit.

The invention relates to the technical field of microbial food fermentation, and particularly discloses pediococcus acidilactici RM1, a separation method and application, and the pediococcus acidilactici RM1 is characterized in that the preservation number of the pediococcus acidilactici RM1 is GDMCC NO.66765; the preservation unit of the pediococcus acidilactici RM1 is Guangdong Microbial Culture Collection Center; the preservation name of the pediococcus acidilactici RM1 is pediococcus acidilactici RM1, and the preservation name of the pediococcus acidilactici RM1 is pediococcus acidilactici RM1. The preservation time of the pediococcus acidilactici RM1 is July 28, 2025. The method has the characteristics of bright red color, difficulty in deterioration during storage and ideal quality and flavor.

The invention relates to the technical field of microorganisms, in particular to a pediococcus acidilactici ZF636 strain and application of the pediococcus acidilactici ZF636 strain. The pediococcus acidilactici strain ZF636 is obtained by screening, is salt-resistant and acid-resistant, has relatively strong ester production capacity, and particularly has high yield of isoamyl acetate; the strain is used for high-salt food fermentation, the content of ester substances, especially isoamyl acetate, of a product and the total amount of volatile compounds can be remarkably increased, meanwhile, the sauce flavor, the ester flavor, the delicate flavor and the strong flavor of the product are improved, the flavor of the product is more balanced and richer, and the flavor and the overall quality of the product are comprehensively improved.

The invention discloses a probiotic composition, fermented yoghurt and application of the probiotic composition and the fermented yoghurt in improving related indexes of athletes. The probiotic composition comprises bacillus subtilis SP-8-5, lactobacillus plantarum YM-4-3, lactobacillus plantarum AY01 and pediococcus acidilactici LH01. The composition of intestinal microbial populations can be adjusted through a specific compounding method, the abundance of harmful bacteria is reduced, the abundance of beneficial bacteria is improved, the immunity of intestinal tracts is enhanced, and the integrity of intestinal barriers of athletes is maintained. Meanwhile, the composition has a positive improvement effect on related exercise indexes such as plasma amino acid, excrement metabolites and exercise performance, and can be used as an effective exercise supplement to be applied to athletes.

The invention relates to the technical field of animal anti-stress nutrition regulation and control, in particular to a curcumin and compound lactic acid bacteria combined tablet preparation which comprises the following components in percentage by weight: 40-60% of curcumin, 2-3% of compound lactic acid bacteria powder, 30-60% of skim milk powder, 0.2-0.5% of magnesium stearate and 0.2-0.6% of talcum powder. Wherein the compound lactic acid bacteria powder is composed of lactobacillus acidophilus and pediococcus acidilactici according to the viable count ratio of 1: 2-2: 1, and the viable count concentration of the compound lactic acid bacteria powder is 2.5 * 10 < 10 >-7.5 * 10 < 10 > cfu / g. The curcumin is used as prebiotics, the compound lactic acid bacteria are used as probiotics, a proper amount of auxiliary materials are added, the curcumin and lactic acid bacteria compound tablet is prepared, on one hand, the purpose of slow release in rumen is achieved, on the other hand, through the synergistic effect of the curcumin and the compound probiotics, the in-vivo anti-oxidation and anti-stress effects are improved, and the intestinal health of animals can be improved.

The invention provides a pediococcus acidilactici strain FSE3 with high phenyllactic acid yield and application of the pediococcus acidilactici strain FSE3, and belongs to the technical field of functional microorganisms. The pediococcus acidilactici strain FSE3 for producing phenyllactic acid is screened from a dreg vinegar fermentation system, and the content of phenyllactic acid produced by metabolism of the strain FSE3 is 2.1 g / L; when the strain is applied to fermentation of the dregs vinegar, the content of phenyllactic acid in the dregs vinegar is remarkably increased, the flavor and quality of the dregs vinegar can be greatly improved, and a new way is provided for development of vinegar or other fermentation products.

Probiotic compositions comprising Bacillus subtilis, Bacillus licheniformis and Pediococcus acidilactici in amounts effective for promoting digestive health, decreasing endotoxemia, decreasing diarrhea, decreasing vomiting and increasing the digestibility of foodstuffs in dogs.

The invention provides pediococcus acidilactici SCFF996 with high EutE enzyme activity and application of the pediococcus acidilactici SCFF996 in a hangover alleviating and liver protecting product, and belongs to the technical field of microorganisms. Wherein the pediococcus acidilactici SCFF996 is preserved in the China General Microbiological Culture Collection Center, and the preservation number of the pediococcus acidilactici SCFF996 is CGMCC (China General Microbiological Culture Collection Center) No. 33405. The pediococcus acidilactici SCFF996 provided by the invention has very good EutE enzyme activity, ethanol tolerance, acid resistance and cholate resistance, can inhibit pathogenic bacteria, is easy to culture and high in reproduction speed, and has remarkable advantages in production of alcohol effect dispelling and liver protecting products.

The invention discloses pediococcus acidilactici capable of reducing blood sugar and a preparation method of the pediococcus acidilactici. The strain is pediococcus acidilactici Pa-PG-10; the strain is named as Pediococcus ilactici, the preservation number is CGMCC (China General Microbiological Culture Collection Center) No.31866, the preservation time is September 4, 2024, the preservation unit is China General Microbiological Culture Collection Center, and the address is No.3, Courtyard 1, Beichen West Road, Chaoyang District, Beijing. The invention has the advantage of good use effect, and solves the problems that the existing probiotics still have obvious insufficiency in the aspects of survival rate, oxidation resistance, blood sugar reducing efficiency and the like in the gastrointestinal tract environment and are difficult to meet clinical requirements.

The present invention relates to a composition comprising a Pediococcus acidilactici SY23 strain (Accession number KCCM 13473P) or a culture thereof as an active ingredient for preventing, alleviating, or treating arthritis.

The application discloses a method for extracting pectin from coffee mucilage by using microorganisms, and belongs to the field of microbial fermentation. The method comprises the following steps: inoculating Pediococcus acidilactici and Pichia kluyveri compound bacterial liquid with a compound ratio of 2:1 into coffee fresh beans in a fermentation tank, inoculating the bacterial liquid at a concentration of 7logCFU / mL, fermenting at a temperature of 32 DEG C, and fermenting for 36 hours. After the pectin layer is gradually separated from the coffee beans, the pectin in the mucilage is extracted and used for preparing thickening agents, emulsifying agents and gel agents in food.

The invention belongs to the technical field of microecological preparations, and provides an animal microecological preparation for promoting intestinal health and a preparation method thereof. The preparation method comprises the following steps: firstly, respectively culturing lactobacillus reuteri and pediococcus acidilactici in an MRS culture medium, culturing bacillus subtilis in an LB culture medium, and culturing saccharomyces cerevisiae in a YPD culture medium to obtain high-activity bacterial liquid; the method comprises the following steps: mixing a multi-strain bacterial liquid with a substrate containing soybean meal hydrolysate, wheat bran and the like, and carrying out staged fermentation, so as to realize metabolism synergy among different strains; then, mixing the fermentation product with skimmed milk powder, maltodextrin and glycerol, and performing freeze drying to prepare a multi-strain probiotic preparation; and finally, mixing the probiotic preparation with nisin, pediococcus acidilactici, fructo-oligosaccharide and xylooligosaccharide, and performing vacuum drying to prepare the microecological preparation, so that the microecological preparation can effectively regulate the microecological balance of animal intestinal tracts, enhance the health level and reduce the use of antibiotics, and has remarkable economic and ecological benefits.

This invention discloses *Pediococcus lactis* TC-4, which simultaneously degrades nucleosides, purines, and uric acid, and its applications. *Pediococcus lactis* ( Pediococcus acidilactici This invention relates to *Pediococcus lactis* TC-4, with accession number GDMCC No: 67936. *Pediococcus lactis* TC-4 of this invention can efficiently degrade three nucleosides (guanosine, adenosine, and inosine), three purines (guanine, xanthine, and hypoxanthine), and uric acid in vitro. *Pediococcus lactis* TC-4 of this invention can effectively reduce serum uric acid levels in broiler chickens, alleviating and treating hyperuricemia. Compared with traditional chemical drugs for treating hyperuricemia and / or gout, this invention has no toxic side effects on the ecological environment, no residue risk, and is green and safe. This invention has been confirmed at multiple levels, including genetic and animal studies, to have no potential harm to humans, demonstrating its advantages of safety and high efficiency.

The present application relates to a Pediococcus acidilactici capable of reducing the activation of hippocampal microglia cells and its application, belonging to the technical field of microorganisms. The Pediococcus acidilactici described in the present application is Pediococcus acidilactici CCFM1344, which was preserved in the Guangdong Microbial Culture Collection Center on September 12, 2023, with the preservation number GDMCC NO.63800. The preservation address is Building 59, 5th Floor, Guangdong Microbial Institute, 100 Middle Martyrs Road, Guangzhou. The Pediococcus acidilactici described in the present application can inhibit the over-activation of microglia cells caused by chronic stress, reduce the concentration of pro-inflammatory factors in the hippocampus of the brain, thereby relieving the activation of microglia cells in the hippocampus of the brain caused by chronic stress, and has excellent application prospects.

The invention relates to the technical field of probiotics, in particular to intestinal tract source pediococcus acidilactici of Yanqu county in Tibet and fat reducing application thereof. The pediococcus acidilactici disclosed by the invention is preserved in the China General Microbiological Culture Collection Center on April 29, 2025, and the preservation number is CGMCC NO.34406; the strain has the characteristics of acid resistance, cholate resistance and stress resistance, and has high survival rate and planting efficiency; the strain is free of hemolysis, free of toxic factors and high in safety; the strain can secrete short-chain fatty acid and antibacterial peptide, inhibit pathogenic bacteria and promote intestinal barrier repair; short-chain fatty acid generated by metabolism of most of carbon water by the strain can be directly absorbed by intestinal epithelial cells, and can be used as an energy substance to replace partial glucose demand, so that the metabolism energy consumption is reduced, the energy conversion rate of feed is improved, the feed conversion is promoted, and the effects of reducing fat and weight and improving the non-alcoholic fatty liver disease are achieved.

The invention provides pediococcus acidilactici HC-2, a fermentation method for fermenting radix astragali through the pediococcus acidilactici HC-2 and application, and relates to the technical field of biological medicine, the pediococcus acidilactici HC-2 is preserved in the China Center for Type Culture Collection on January 20, 2025; the preservation number is CCTCC (China Center For Type Culture Collection) CNO: M 2025183; the preservation address is Wuhan University, Wuhan, China; the Pediococcus acidilactici HC-2 is named as Pediococcus acidilactici HC-2 in taxonomy.

This application belongs to the field of microbial technology, and mainly relates to a strain of *Pediococcus lactis* BPA03 and its applications. *Pediococcus lactis* BPA03 is classified and named *Pediococcus lactis*. Pediococcus acidilactici This *Pediococcus lactis* strain BPA03 was deposited on September 28, 2025, at the China General Microbiological Culture Collection Center (CGMCC), located at No. 3, Courtyard 1, Beichen West Road, Chaoyang District, Beijing, with accession number CGMCC No. 36109. It inhibits skin melanin deposition and improves UV photoaging, suppresses the gene expression levels of immune factors such as IL-1β, IL-6, IL-8, and TNF-α, improves the activities of superoxide dismutase, catalase, and glutathione peroxidase, inhibits vinorelbine-induced neutropenia, and improves the inhibition of immune factor expression induced by vinorelbine, thus exhibiting comprehensive anti-aging effects.