Pediococcus acidilactici HEW-AP27 and application thereof

A HEW-AP27, Pediococcus lactis technology, applied in the field of probiotics, can solve the problems of increased drug resistance of strains, increased drug residues, impact on animal immunity, etc., and achieves strong adhesion performance, strong acid-producing performance, strong Effect of bile salt tolerance
CN108504601AActive Publication Date: 2018-09-07BEIJING HESWOF BIOTECH CO LTD

Patent Information

Authority / Receiving Office
CN · China
Current Assignee / Owner
BEIJING HESWOF BIOTECH CO LTD
Publication Date
2018-09-07

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Abstract

The invention discloses newly separated pediococcus acidilactici HEW-AP27 collected in the CGMCC (China General Microbiological Culture Collection Center) in the Institute of microbiology of CAS (Chinese Academy of Sciences) in Beichen west road No.1 yard No.3 in Chaoyang District of Beijing with the postal code of 100101 on March 7, 2018, with the collection number of CGMCC NO.15419. The invention also provides a preparation method of a viable pediococcus acidilactici preparation. The method comprises the steps as follows: the pediococcus acidilactici is used as a fermentation strain, an optimized fermentation process and a fermentation medium are adopted, discharging is performed after first-stage, second-stage and third-stage culture, active bacterial sludge is obtained through centrifugation, a stabilization protective agent is added, granulation is performed through a granulator, a coating liquid is added to a coating machine for coating, and finally, the viable pediococcus acidilactici preparation is obtained. The pediococcus acidilactici HEW-AP27 has acid resistance, cholate resistance and high-temperature resistance, has high acid producing performance and can inhibit growth and reproduction of pathogenic bacteria.
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Description

technical field

[0001] The invention relates to probiotics, in particular to a strain of Pediococcus acidilactici (Pediococcus acidilactici) HEW-AP27 and its application. Background technique

[0002] Pediococcus acidilactici is one of the important members of probiotics, and most of them are one of the probiotics on the body surface and internal mucosal surface of animals. In addition, Pediococcus lactis also produces acid, which can regulate the gastrointestinal flora and maintain the intestinal microecological balance. It can antagonize pathogenic microorganisms in animals, competitively inhibit pathogenic microorganisms, enhance the immune function of animals, produce beneficial metabolites, activate the activity of acid protease, participate in the metabolism of the body, and prevent the production of harmful substances.

[0003] At present, the abuse of antibiotics, chemically synthesized drugs, and hormones in feed and animal husbandry has caused very serious consequ...

Claims

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