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58results about How to "Achieve controllability" patented technology

Electric energy metering error evaluation method and system of direct current charging pile, equipment and medium

PendingCN121831661AEfficiently quantify transient metrology deviationsadaptableElectrical measurementsClosed loop analysisControllability
The invention discloses an electric energy metering error evaluation method and system for a direct current charging pile, equipment and a medium, and the method comprises the steps: constructing an electric energy disturbance response function based on transient voltage and transient current, and effectively quantifying the transient metering deviation caused by measurement lag, voltage drop, current peak and other factors in the actual operation of the direct current charging pile. Error reconstruction modeling has higher dynamic adaptive capacity and physical rationality, the limitation that in the prior art, the influence of the high-variable-load working condition on metering cannot be reflected is broken through, and the accuracy and timeliness of direct-current charging pile error monitoring are greatly improved. Besides, a standard error is introduced to carry out fitting calibration on a reconstruction error and carry out energy conservation verification, thereby realizing verifiability on a physical level and controllability in engineering implementation, enhancing credibility and authority of an evaluation result, constructing a closed-loop analysis mechanism from error evaluation to metering correction and then to conservation verification, and improving reliability and reliability of the evaluation result. And the closeness and the adaptive capability of the overall error evaluation are improved.
Owner:STATE GRID HUNAN POWER SUPPLY SERVICE CENT (METROLOGY CENT) +2

Seawater soaking wound hydrogel dressing as well as preparation method and application thereof

PendingCN121796672ABroad spectrum antibacterialHas inflammation regulationBandagesWound carePharmaceutical Substances
The invention provides a seawater soaking wound hydrogel dressing and a preparation method thereof, a drug-loaded nano system 4OI (at) ZIF-8 (at) PAD with a core-shell structure is constructed, an anti-inflammatory drug 4-octyl itaconic acid and zinc ions are jointly encapsulated in a ZIF-8 framework, and a polydopamine coating is wrapped, so that synergistic loading and controllable release of the drug and metal ions are realized. According to the dressing, dopamine modified hyaluronic acid is used as a matrix, a temperature-sensitive material and an enzyme catalysis cross-linking system are combined, stable gel can be rapidly formed in situ within 5 seconds, and the dressing has excellent tissue adhesion performance (the adhesion strength reaches 6.7 kPa). Experiments prove that the hydrogel dressing has the characteristics of broad-spectrum antibiosis, inflammation regulation and control and long-acting release. Animal experiments prove that the healing rate of seawater soaking wounds treated by the dressing on the twelfth day is as high as 95.7% and is remarkably superior to that of a commercial silver ion gel control group, scars are less after healing, and an efficient, safe and easy-to-implement scheme is provided for marine environment wound nursing.
Owner:CHINESE PEOPLES LIBERATION ARMY ARMY SPECIAL MEDICAL CENTER

Control method and device for constant arc length welding of 1.6mm diameter aluminum alloy welding wire

This invention provides a control method and apparatus for constant arc length welding of 1.6mm diameter aluminum alloy welding wire, relating to the field of aluminum alloy welding technology. The control method for constant arc length welding of 1.6mm diameter aluminum alloy welding wire is applied to a consumable electrode welding method, comprising multiple consecutive welding cycles. Each welding cycle includes a pulse welding period and an arc circuit detection period following the pulse welding period. The arc circuit detection period includes a wire forward feed period, a first arc detection period, a second arc detection period, and a wire retraction period. Through the synergistic effect of multi-stage speed control and current regulation, the pulse arc length is precisely maintained during the wire retraction period, achieving controllability of the droplet transfer process and arc length stability. This effectively solves the problems of arc drift, wire sticking, and poor weld bead formation in existing technologies, enabling precise control of the arc length and reducing wire sticking, thereby improving welding stability.
Owner:NINGBO XINTAI MACHINERY +1

A method for controllable preparation of nanoparticles using a multi-channel microreactor

This invention discloses a method for controllable preparation of nanoparticles using a multi-channel microreactor. The method utilizes a microchannel reactor to segment droplets and prepare quantitatively synthesized nanoparticles with controllable particle size. The invention employs capillary action to draw the reaction solution into the microchannel, segmenting one or more droplets (each droplet into 10-100 portions). By changing the width of the microchannel, controllable preparation of nanoparticles within a small range (±3 nm) can be achieved; by changing the length of the microchannel, controllable preparation of nanoparticles within a large range (±10-30 nm) can be achieved. Furthermore, the reactor structure of this invention is simple, enabling highly precise and quantitative synthesis of various nanoparticles. Compared to large-scale reactors, the miniaturization of the synthesis reaction in this invention effectively reduces energy waste and safety hazards, making it highly valuable for applications in safe chemical engineering, green chemical engineering, high-efficiency chemical engineering, microchemical engineering, and precise reaction monitoring.
Owner:INST OF CHEM CHINESE ACAD OF SCI

An industrial anti-corrosion coating and its preparation method

This invention relates to the field of coatings, specifically to an industrial anti-corrosion coating and its preparation method. The coating comprises a film-forming resin, a curing agent, a solvent, and an anti-corrosion composite nanofiller. The anti-corrosion composite nanofiller has a three-layer structure: a core layer of mesoporous silica loaded with an organic corrosion inhibitor; a middle shell layer of in-situ grown amino-functionalized metal-organic framework material; and an outer layer of low surface energy formed by modification with a hydrophobic modifier.
Owner:LIAONING MAIQI NEW MATERIAL GRP CO LTD

Control device of wheeled robot

ActiveCN224059846UAchieve precise controlachieve simplificationManipulatorControl engineeringElectric machinery
The utility model relates to the technical field of robots, in particular to a wheeled robot control device which comprises a transmission body, a carrier, a rubber ball wheel and a transmission assembly, the carrier is provided with the transmission body, the transmission assembly is used for driving the rubber ball wheel to axially rotate, and the rubber ball wheel is arranged on the side face of the carrier. The transmission assembly is arranged in the carrier. The motor transmits power to the rubber ball wheel, simplification and high efficiency of the robot structure are achieved, the elastic characteristic of the rubber ball wheel is beneficial to impact absorption, damage to the internal structure of the robot is reduced, the service life of equipment is prolonged, the transmission body is finely adjusted through the micrometer, and the service life of the equipment is prolonged. The controllability and accuracy of contact between the ball control part and the football are achieved, and the adjusting process of the ball control strength of the ball control structure is greatly simplified through the application of the spring.
Owner:HUNAN UNIV

Anti-hypoxia sputum suction tube

PendingCN121944263Aavoid suffocationprevent backflowSuction devicesValvesHypoxia (medical)Visual monitoring
The invention relates to the technical field of medical instruments, and discloses an anti-hypoxia sputum suction catheter which comprises an oxygen uptake catheter and a sputum suction catheter assembly arranged in the oxygen uptake catheter in a penetrating mode, the right end of the oxygen uptake catheter and the right end of the sputum suction catheter assembly are communicated with a three-way pipe, and the periphery of the three-way pipe is fixedly connected with a fixing shell. The left end of the three-way pipe is fixedly connected with a check valve, the right end of the three-way pipe is communicated with a branch pipe and a connecting pipe, the tail end of the connecting pipe is provided with a pneumatic pump, and the middle of the pneumatic pump is fixedly connected with an adjusting valve. By means of the coaxial double-tube structure and the three-way tube shunt design, continuous oxygen supply is kept while the sputum aspirator goes deep into an airway for sputum aspiration, suffocation of a patient is effectively prevented, accurate adjustment and visual monitoring of negative pressure are achieved by means of the pneumatic pump assembly integrating the adjusting valve and the display screen, and the safety and efficiency of sputum aspiration operation are remarkably improved.
Owner:TIANJIN CITY THIRD CENT HOSPITAL

Meta-aramid fibrid and preparation method thereof

The invention discloses meta-aramid fibrid and a preparation method thereof, the meta-aramid fibrid comprises, by dry weight, 90.0-99.5 wt% of meta-aramid resin and 0.5-10.0 wt% of an amphiphilic block copolymer additive, and the additive comprises at least one of p-N-methyl pyrrolidone or N, N-dimethyl pyrrolidone or N, N-dimethyl pyrrolidone or N, N-dimethyl pyrrolidone or N, N-dimethyl pyrrolidone or N, N-dimethyl pyrrolidone or N, N-dimethyl pyrrolidone or N, N-dimethyl pyrrolidone or N, N-dimethyl pyrrolidone or N, N-dimethyl pyrrolidone. A first block having an affinity for N, N-dimethylacetamide; and at least one second block having an affinity for water. The preparation method comprises the following steps: adding an additive into a meta-aramid resin polymerization liquid to form a composite resin polymerization liquid; injecting the composite liquid into a precipitation bath composed of N-methyl pyrrolidone or N, N-dimethylacetamide and water through a dispersing device, and after precipitation, carrying out solid-liquid separation, washing and drying to obtain the fibrid. Through the synergistic effect of a specific additive and a precipitation bath system, the microstructure of the fibers is actively regulated and controlled, and the specific surface area and the surface roughness of the fibers are improved, so that the tensile strength and the internal bonding strength of finished paper are remarkably enhanced, and meanwhile, the inherent high-temperature-resistant, flame-retardant and insulating properties of meta-aramid fibers are kept.
Owner:WUJIANG YAXIMA TEXTILE CO LTD

A ship maritime collision avoidance rule real scene training and evaluation method and system

PendingCN122290404AAchieve scalabilityachieve controllabilityMaritime navigationVoice communication
This invention belongs to the field of intelligent perception and simulation training technology for maritime navigation. It discloses a method and system for realistic training and evaluation of ship collision avoidance rules at sea. By constructing a hierarchical question bank, it generates scenario assembly lists and uniformly schedules ship motion simulation, 3D visual scenes, radar / AIS fusion display, and voice communication interaction. During training, it collects control inputs, motion states, target information, and communication records to form a traceable chain of evidence, and aligns sampling based on evaluation anchor points. An automatic scoring model is established based on result and process indicators, outputting an evaluation report with sub-scores, evidence location, a list of violations, and retraining suggestions. It is suitable for teaching, retraining, and assessment, improving the efficiency and achievement rate of collision avoidance decision-making training.
Owner:COSCO SHIPPING +1

A platelet-rich plasma preparation device

The utility model relates to the field of biomedical technology, concretely is a kind of platelet-rich plasma preparation device.The device includes storage tube, sealing cover and piston assembly.Storage tube is divided into storage part and injection part, and stop structure is arranged in storage cavity;Sealing cover is in interference fit with injection part and can be punctured, and closed blood sampling is realized in combination with vacuum negative pressure cavity.Piston assembly realizes locking and release by the cooperation of elastic movable head and stop structure, ensures that each blood layer is independently pushed after centrifugal stratification, and avoids cross contamination.Storage tube is made of transparent material and is provided with scale, so that stratification state and accurate separation can be observed.The device is integrated with blood sampling, centrifugation and extraction functions, and PRP preparation can be completed through single centrifugation and push-pull piston, which is convenient to operate and high in efficiency.The utility model solves the problems of complex operation, low separation efficiency and easy pollution of traditional method, and significantly improves the reliability and practicality of PRP preparation.
Owner:PAIFELO MEDICAL TECHNOLOGY (JIAXING) CO LTD

Cultivated land reserve resource investigation and evaluation method and system based on convolutional neural network

The invention discloses a cultivated land reserve resource investigation and evaluation method and system based on a convolutional neural network, particularly relates to the technical field of remote sensing image processing and cultivated land resource evaluation, and is used for solving the problem that an evaluation result is not accurate due to the fact that a preceding stage segmentation error is transmitted and amplified by a backward stage in a cascaded convolutional neural network. By identifying non-cultivated land transition zone pattern spots in the remote sensing image, a boundary fuzzy region is accurately positioned by adopting a fractal dimension change rate and optimal transmission cost distance dual-threshold judgment criterion; secondly, extracting a feature activation track of a transition zone pattern spot in the convolutional network, and establishing an error propagation weight coefficient calculation model; then, combining a boundary channel response value and a weight coefficient to generate a weighted feature offset, and constructing an error compensation mask; and finally, through pixel-level fusion of a mask and a post-level feature map, a terrain gradient and a connection degree evaluation index are corrected, an error transfer effect of a cascade architecture is significantly inhibited, and the reliability of a cultivated land reserve resource grading result is improved.
Owner:SHANDONG KOTEI INFORMATION TECH CO LTD

Anti-erosion air brick and preparation process thereof

The invention relates to the technical field of air bricks, in particular to an anti-erosion air brick and a preparation process thereof, and the anti-erosion air brick comprises the following components: fused magnesite particles, crystalline flake graphite, modified zirconia fine powder, metal aluminum fine powder, boron carbide fine powder and phenolic resin. According to the invention, through modified titanate and modified boric acid, a composite coating layer is constructed on the surface of zirconium oxide, and a titanium dioxide compact layer is generated in situ by using a titanium component at a high temperature, so that erosion of calcium oxide in slag is blocked; meanwhile, the boron component forms a high-melting-point phase to fill grain boundary pores, and slag permeation and harmful dendritic crystal precipitation are inhibited, so that the structural stability and slag corrosion resistance of the air brick are improved.
Owner:大石桥市冠诚耐火材料有限公司

A kind of automobile interior foamed material processing prestorage device

ActiveCN224545108UImplement partitioned storageachieve controllabilityMaterials processingHolding tank
The utility model discloses an automobile interior decoration foamed material processing prestorage device, including lower storage jar and upper storage jar, the upper storage jar fixed connection is in the upper end of lower storage jar, the upper storage jar and lower storage jar are communicated through the intercommunication passage, be equipped with the first electromagnetic valve on the intercommunication passage, the left side of upper storage jar and lower storage jar all have the feeding hopper of intercommunication, be equipped with the first stirring subassembly in the upper storage jar, be equipped with the second stirring subassembly in the lower storage jar, the first stirring subassembly includes the vertical rod of rotation connection in the upper storage jar top, the outer wall of vertical rod is fixedly connected with a plurality of first stirring rod, the second stirring subassembly includes the crosspiece of rotation connection on the inner wall of lower storage jar left and right sides. The device can realize two component materials isolated storage, automatic proportioning mixing, and possess environmental monitoring function's prestorage device to promote the processing efficiency of automobile interior decoration foamed material and product quality, reduce production cost and artificial error.
Owner:HEFEI FUZE AUTO PARTS MFG CO LTD

Preparation method of graphene composite phase change thermal interface material

The application relates to a preparation method of a graphene composite phase change thermal interface material. An oxidized graphene dispersion liquid is provided, a centrifugal roller coating and a layer-by-layer drying process are adopted to form a multilayer oxidized graphene unit layer on a substrate, and an oxidized graphene film is obtained; the oxidized graphene film is placed in a limited space, gradient heat reduction treatment is carried out, the film is controllably expanded in the out-of-plane direction, and a reduced graphene oxide film with a micro-nano cavity structure is formed; the reduced graphene oxide film is subjected to graphitization treatment, and a graphene micro-nano cavity film is obtained; through a vacuum impregnation method, a molten phase change material is filled into the micro-nano cavity structure of the graphene micro-nano cavity film. The thermal interface material has high phase change enthalpy (196.2 J / g), excellent thermal performance (in-plane thermal conductivity 65.5 W.m ‑1 ·K ‑1 , out-of-plane 21.9 W.m ‑1 ·K ‑1 , and low interface thermal resistance (0.575 K.cm 2 ·W ‑1 ).
Owner:PEKING UNIV

High-strength high-modulus polyimide fiber and method for producing the same

PendingCN122610232ASolve the problem of generation or even explosionachieve controllability
The application relates to the technical field of polyimide materials, and discloses a high-strength and high-modulus polyimide fiber and a preparation method thereof, which comprises the following steps: mixing aromatic dianhydride and nitrogen-containing organic base unit diamine monomers, and carrying out kettle polymerization to obtain rigid polymerization liquid 1; mixing aromatic dianhydride and flexible diamine monomers, and carrying out kettle polymerization to obtain flexible oligomer polymerization liquid 2; conveying the rigid polymerization liquid 1 and the flexible oligomer polymerization liquid 2 into a screw reactor to carry out secondary reaction, and obtaining polyamide acid spinning liquid; filtering and defoaming the polyamide acid spinning liquid, and obtaining polyamide acid fiber through dry spinning; and carrying out thermal imidization and thermal drawing on the polyamide acid fiber to obtain the high-strength and high-modulus polyimide fiber. The application adopts kettle pre-polymerization + screw final polymerization segmented polymerization, avoids gel explosion polymerization, and considers both high-strength and high-modulus and spinnability of the fiber, and cooperates with a channel in-situ catalytic cyclization to synergistically improve fiber orientation and mechanical properties.
Owner:JIANGSU AOSHEN HI TECH MATERIALS CO LTD

A xeno-free culture method of hiPSCs and a quality monitoring method thereof

This invention discloses a xenogeneic-free culture method for hiPSCs and its quality monitoring method. The xenogeneic-free culture method includes the following steps: hiPSC cells are seeded into the wells of a culture plate coated with VTN-N matrix gel, and cultured for the first stage using E8 complete medium containing 5-15 µM Y-27632. After 20-30 h of culture, the medium is replaced with conventional E8 complete medium without Y-27632 for the second stage of culture, until the cell confluence reaches 60%-80%. This xenogeneic-free culture method ensures efficient cell expansion under conditions with clearly defined chemical composition. This method further optimizes the seeding density and culture period of hiPSCs, controls cell passage at 60%-80% confluence, and significantly reduces the risk of spontaneous differentiation by limiting the maximum culture time and upper limit of confluence.
Owner:SHANGHAI INNOSTAR BIO TECH

Multifunctional indoor piling test device for offshore wind power steel pipe pile

The invention belongs to the technical field of offshore wind power foundation engineering tests, and discloses a multifunctional indoor piling test device for offshore wind power steel pipe piles, which realizes indoor simulation and contrast tests of various steel pipe pile sinking modes by arranging a static pressure pile sinking device, an excitation pile sinking device and a power piling device on the same test platform. The systematicness and comparability of the test are improved; through structural cooperation of the support sliding rail and the equipment sliding rail, overall displacement of a test area is achieved, and resetting of soil body conditions and repeated testing are facilitated; a displacement sensor, a pressure sensor and an acceleration sensor are integrated in a pile cap, the displacement change, the stress state and the dynamic response in the pile sinking process of the steel pipe pile are synchronously monitored, and a reliable data basis is provided for pile sinking mechanism analysis and key parameter research; through the synergistic effect of the servo control system and the information acquisition system, controllable loading and state dynamic correction in the pile sinking process are achieved, and the stability and controllability of the test process and the reliability of the result are enhanced.
Owner:TIANJIN UNIV

Preparation method of a double-crosslinked 3D printing bone repair scaffold

ActiveCN121338091Bachieve controllabilityachieve biological activityAdditive manufacturing apparatusProsthesis3d printBiphasic calcium phosphate
The application relates to the technical field of biomedical materials, and specifically discloses a preparation method of a double-crosslinked 3D-printed bone repair scaffold. The scaffold is made of a biphasic calcium phosphate matrix and a gelatin methacrylate hydrogel outer layer. The preparation method comprises the following steps: firstly, preparing biphasic calcium phosphate ink, and constructing a porous scaffold blank through 3D printing; then, carrying out double-crosslinking treatment of calcium chloride solution and glutaraldehyde solution in sequence to obtain a scaffold matrix with enhanced mechanical properties; then, preparing gelatin methacrylate hydrogel loaded with modified teriparatide, and compounding the gelatin methacrylate hydrogel with the scaffold matrix; and finally, obtaining the final product after blue light crosslinking and solidification. The bone repair scaffold has good biocompatibility and osteogenic activity, and can effectively promote bone defect repair. In addition, the preparation method is controllable and has good repeatability, the structure of the scaffold is accurately controlled through the 3D printing technology, and a new approach is provided for the preparation of personalized bone repair materials.
Owner:LANZHOU UNIV SECOND HOSPITAL

Automatic mobile phone shell packaging device based on AI digital twin factory

The invention relates to an automatic mobile phone shell packaging device based on an AI digital twinning factory, which comprises a rack and a mobile phone shell conveying belt continuously penetrating through the inner space of the rack, and further comprises a plastic support feeding conveying line, the visual positioning system is arranged in the rack and is used for identifying the mobile phone shells on the mobile phone shell conveying belt and the plastic supports on the assembly positions; a multi-axis movement mechanism; the pickup actuator is mounted at the moving tail end of the multi-axis moving mechanism and used for executing grabbing and releasing operation according to the identification information; and the finished product transferring mechanism is used for outputting the assembled plastic support to the mobile phone shell conveying belt. According to the automatic packaging device, through the design that the mobile phone shell conveying belt continuously penetrates through the rack, the automatic packaging device can be directly integrated on the premise of not cutting off and not transforming an original production line, a unique transformation mode of penetrating but not breaking is formed, and therefore the physical and functional continuity of the original production line is kept; and the reconstruction difficulty, the engineering complexity and the comprehensive cost of automatic upgrading are reduced.
Owner:ZHENGZHOU UNIVERSITY OF LIGHT INDUSTRY

A high mineral content stone iron aluminate cement material and a method of making the same

ActiveCN121990771BGuaranteed early strengthinhibit targeted poisoningAluminateAluminite
The application relates to the technical field of cement materials, and particularly discloses a high ore fused stone ferrite aluminate cement material and a preparation method thereof. The cement material is prepared by jointly grinding and treating high belite ferrite aluminate cement clinker and a modifier. The modifier is composed of succinyl phosphonate, a quaternary ammonium salt and an aluminum source. The molecular formula of the succinyl phosphonate is HOOC-CH2-CH2-CO(PO3H2). The modifier composed of succinyl phosphonate, a quaternary ammonium salt and an aluminum source is used to perform mechanochemical coupling modification on the belite ferrite aluminate cement clinker, multi-level interface interaction occurs under the induction of mechanical force, directional poisoning and growth inhibition of calcium aluminate crystal nuclei are realized, the early strength of the cement is maintained, and the volume stability of the cement material is significantly improved.
Owner:UNIV OF JINAN

Multi-dimensional traffic grayscale routing method and system based on traffic white list

PendingCN121770835ARecognizableAchieved controllabilitySecuring communicationRouting decisionEngineering
The invention provides a multi-dimensional traffic grayscale routing method and system based on a traffic white list, and belongs to the technical field of data processing, and the method comprises the steps: receiving client request data containing a user identifier, channel information and at least one custom scene attribute; performing legality verification on the user identifier, the channel information and the custom scene attribute; matching the request data passing the verification with a preset multi-dimensional white list rule, the multi-dimensional white list rule at least comprising a user white list, a channel white list and at least one extension type white list, and the white lists of different dimensions have priorities; determining a target service version according to the matching result and the priority; and executing a routing decision based on the determined target service version, and forwarding the request data to the corresponding server, thereby realizing accurate identification and controllable distribution of the gray traffic.
Owner:CHANGSHA WEIFUTONG TECH SERVICE CO LTD

Flexible energy storage spring type robot bionic jumping foot type mechanism and control method thereof

The invention belongs to the technical field of robots, and particularly relates to a flexible energy storage spring type robot bionic jumping foot type mechanism and a control method thereof. The mechanism comprises a motor, a main body part composed of a transmission module, a disengaging module and a rope coil spring transmission module, an upper movable rod and a lower movable rod which are connected with the main body part, and a foot jumping assembly rotationally connected with one end of the lower movable rod. The transmission module amplifies the output torque of the motor, mechanical energy is stored through the rope coil spring transmission module, by arranging the disengaging module, the transmission module and the rope coil spring transmission module are selectively connected or disengaged in different working states, the movable rod rotates to drive the foot jumping assembly, and jumping of the robot is achieved. The robot is compact in structure, high in energy utilization rate, good in jumping stability and suitable for small jumping robots and complex terrain moving robots.
Owner:NANJING UNIV OF SCI & TECH

Large-area organic single crystal transistor and preparation method and application thereof

The invention discloses a large-area organic single crystal transistor and a preparation method and application thereof, and belongs to the field of organic semiconductors. The organic single crystal transistor sequentially comprises a flexible seamless embedded metal electrode, a metal oxide layer, an organic semiconductor layer, a polymer insulating layer and a patterned gate layer from bottom to top. The organic single crystal transistor provided by the invention has high device performance and no hysteresis phenomenon; due to the highly uniform carrier mobility, logic gate circuits such as phase inverters, NAND gates and NOR gates and complex circuits such as oscillators can be prepared through circuit design. And a scheme is provided for application, scientific research and industrialization of the organic flexible circuit.
Owner:INST OF CHEM CHINESE ACAD OF SCI

A human leukemia cell-targeting penetrating peptide-modified enzyme-sensitive PDC-type PROTAC as well as a preparation method and application thereof

This invention discloses an enzyme-sensitive PDC-type PROTAC modified with a human leukemia cell-targeting transmembrane peptide, its preparation method, and its applications, belonging to the field of tumor targeted therapy technology. This PDC-type PROTAC is composed of a hypoxia-inducible factor 1α (HIF-1α) protein fragment linked to imatinib via dodecanoic acid, and further modified with the human leukemia cell-targeting transmembrane peptide Cyclo-C9C-R and the cathepsin B-sensitive sequence GFLG. The modified PDC-type PROTAC can release the original drug under the catalysis of cathepsin B, with minimal impact on THP1 cell viability, but effectively inhibits the proliferation of K562 and KU812 cells, degrades target proteins, induces apoptosis, and affects the cell cycle. This gives the PDC-type PROTAC significant advantages in the preparation of anti-tumor drugs, particularly showing promising application prospects in the development of drugs targeting human chronic myeloid leukemia cells and human peripheral blood basophilic leukemia cells, opening up a new field for PROTAC drug development.
Owner:XI AN JIAOTONG UNIV

Floor guardrail

The utility model discloses a floor guardrail, and relates to the technical field of industrial protection facilities. Comprising caps, a flexible outer pipe, fixing screws, a metal base and chemical bolts, the lower portions of the chemical bolts are anchored with embedded steel bar glue, the upper portions of the chemical bolts are fixed with the metal base, the upper ends of supporting rods of the metal base are fixed with the flexible outer pipe through the fixing screws, and the caps are fixed to the two ends of the flexible outer pipe. The utility model has the advantages of convenient installation, strong impact resistance, long service life and the like, and is suitable for division and protection of industrial storage areas.
Owner:BOENBO INTELLIGENT EQUIPMENT (FUJIAN) CO LTD

Prestressed roof truss beam tensioning method

The invention discloses a prestressed roof truss beam tensioning method which comprises the following steps: S1, prefabricating a component: binding a steel reinforcement framework, mounting an embedded part, setting a reserved hole channel, and pouring and maintaining concrete in sequence to form a roof truss beam concrete component with the reserved hole channel; the prestressed steel strand is penetrated into the reserved hole channel, the prestressed steel strand is an intelligent sensing steel strand, the structure of the prestressed steel strand is that an optical fiber rope is replaced or merged into the center wire position or the stranded rope core of the prestressed steel strand, at least a plurality of optical fiber sensors are packaged in the optical fiber rope, and the optical fiber sensors are arranged in the optical fiber rope; and a plurality of steel wires are uniformly arranged outside the optical fiber rope or the central wire. According to the method, the tensioning quality is improved from'result verification 'to'process controllability and result knowing', the controllability and precision of the tensioning process are achieved, the problem that prestress application is unqualified due to unsmooth hole channels, equipment errors and the like is solved, and it is guaranteed that the initial state of the structure is healthy.
Owner:THE 7TH CONSTR CO LTD OF CHINA 15TH CORP +2

Multi-model inference method, device, medium and program product based on graph structure

ActiveCN121503659Bachieve persistenceRealize visualization
The application discloses a multi-model reasoning method and device based on a graph structure, a medium and a program product, wherein the method comprises the following steps: querying a task target node in a graph database and starting from the task target node, and performing reasoning path expansion in the graph database according to a corresponding driving model, wherein the graph database comprises a plurality of directed acyclic graphs, and each directed acyclic graph is obtained by mapping metadata of a registered analysis model; generating a task topology execution graph according to model nodes involved in the expanded reasoning path and the corresponding driving model; and sequentially scheduling actual execution of each model node according to the task topology execution graph, and obtaining an explanation result corresponding to the task target node. The application improves the reasoning execution efficiency by explicitly attributing the analysis model and optimizing the reasoning path by using graph calculation, and improves the intelligence, performance and interpretability of multi-model collaborative analysis.
Owner:BEIJING NEUSOFT VIEWHIGH CO LTD

High-flux anti-pollution composite reverse osmosis membrane and preparation method thereof

The invention discloses a high-flux anti-pollution composite reverse osmosis membrane and a preparation method thereof, and relates to the technical field of water treatment membranes. The composite material comprises a porous support layer, an in-situ mineralized polyamide separation layer and a metal-polyphenol gradient functional layer. The in-situ mineralized polyamide separation layer is formed by carrying out interfacial polymerization reaction on a m-phenylenediamine aqueous phase solution and a trimesoyl chloride organic phase solution containing ammonium hexafluorosilicate, and fluosilicate nano-clusters are generated through in-situ hydrolysis; the metal-polyphenol gradient functional layer is formed by sequentially assembling and competitively coordinating a zirconium source solution and polyphenol solutions with different sodium citrate concentrations. According to the invention, the internal nano-clusters construct a water molecule transmission channel, the balance of anti-pollution performance and water mass transfer resistance is realized through the surface gradient functional layer, the obtained composite membrane has high flux and excellent anti-pollution performance, the preparation method is simple and controllable, and the composite membrane has a good industrial application prospect.
Owner:NINGBO RXHL TECH CO LTD

High-performance nearly-spherical zirconium oxide feeding powder and preparation method thereof

The invention belongs to the technical field of advanced ceramic material preparation, and particularly discloses high-performance nearly-spherical zirconium oxide feeding powder and a preparation method thereof, and the method comprises the following steps: (1) preparing composite precursor liquid; (2) graded controllable thermal conversion; and (3) post-treatment: carrying out heat treatment on the product obtained in the step (2) in an oxidizing atmosphere at 500-700 DEG C for 0.5-3 hours to obtain the zirconium oxide powder. The special structure powder with the dense outside and the inner holes is prepared. The smooth and compact surface endows the powder with excellent fluidity; the internal uniform closed nano-pores properly reduce the particle density and further facilitate flowing, and more importantly, the pores can partially absorb a binder during feed preparation and play roles in'internal stress buffering 'and binder distribution optimization, so that higher powder loading capacity is allowed under the same viscosity, and the feed preparation efficiency is improved. Or lower viscosity and better rheological property can be obtained under the same loading capacity.
Owner:JINYE NEW MATERIAL TECH (KUNSHAN CO LTD

A Multi-Service Broadcast Optical Reception Scheduling Method and System Based on Wavelength Allocation

This application discloses a multi-service broadcast optical reception scheduling method and system based on wavelength allocation, relating to the field of optical network communication technology. The method includes: for broadcast WDM multi-service concurrent reception scenarios, jointly modeling the service request category, time limit, and data size constraints with wavelength resource occupancy status and interference risk; firstly, dynamically grouping available wavelengths based on service category load prediction to achieve adaptive resource boundaries according to service attributes; then constructing a comprehensive priority index including the latest reception time limit, service category, and interference risk of candidate wavelengths, performing ordered cross-priority scheduling, and arranging reception time slots on the target wavelength to generate a wavelength scheduling table and a reception scheduling table; finally, driving the receiver to tune and receive according to time slots using scheduling commands. This improves wavelength utilization while reducing reception conflicts and latency jitter and strengthening critical service assurance.
Owner:SUZHOU AIXIONGSI COMM TECH CO LTD