13427 results about "Companion animal" patented technology

A method and system for physiological gating is disclosed. A method and system for detecting and predictably estimating regular cycles of physiological activity or movements is disclosed. Another disclosed aspect of the invention is directed to predictive actuation of gating system components. Yet another disclosed aspect of the invention is directed to physiological gating of radiation treatment based upon the phase of the physiological activity. Gating can be performed, either prospectively or retrospectively, to any type of procedure, including radiation therapy or imaging, or other types of medical devices and procedures such as PET, MRI, SPECT, and CT scans.

The sensitivity of a motion sensor or detector in a security system is adjusted by a remotely-transmitted signal, such as from a user interface device in the security system. In another approach, a pet wears a transmitter on its collar that transmits a wireless signal to command the motion sensor to adjust its sensitivity, e.g., by entering a pet immune mode, when the pet is in the room that is protected by the motion sensor. In another approach, a remote monitoring site sends instructions to the motion sensor via a communication interface. The sensitivity can be adjusted by adjusting a pulse count, optical gain, or electrical or optical sensitivity of the motion sensor.

A body scanning system includes a CT transmitter and a PET configured to radiate along a significant portion of the body and a plurality of sensors (202, 204) configured to detect photons along the same portion of the body. In order to facilitate the efficient collection of photons and to process the data on a real time basis, the body scanning system includes a new data processing pipeline that includes a sequentially implemented parallel processor (212) that is operable to create images in real time not withstanding the significant amounts of data generated by the CT and PET radiating devices.

A virtual interactive environment enables a surgeon or other medical professional to manipulate implants, prostheses, or other instruments using patient-specific data from virtual reality models. The patient data includes a combination of volumetric data, surface data, and fused images from various sources (e.g., CT, MRI, x-ray, ultrasound, laser interferometry, PET, etc.). The patient data is visualized to permit a surgeon to manipulate a virtual image of the patient's anatomy, the implant, or both, until the implant is ideally positioned within the virtual model as the surgeon would position a physical implant in actual surgery. Thus, the interactive tools can simulate changes in an anatomical structure (e.g., bones or soft tissue), and their effects on the external, visual appearance of the patient. CAM software is executed to fabricate the implant, such that it is customized for the patient without having to modify the structures during surgery or to produce a better fit.

Disclosed are compositions, systems and methods for treating a subject's body, body part, tissue, body fluid cells, pathogens, or other undesirable matter involving the administration of a targeted thermotherapy that comprises a bioprobe (energy susceptive materials that are attached to a target-specific ligand). Such targeted therapy methods can be combined with at least one other therapy technique. Other therapies include hyperthermia, direct antibody therapy, radiation, chemo- or pharmaceutical therapy, photodynamic therapy, surgical or interventional therapy, bone marrow or stem cell transplantation, and medical imaging, such as MRI, PET, SPECT, and bioimpedance. The disclosed therapies may be useful in the treatment of a variety of indications, including but not limited to, cancer of any type, such as bone marrow, lung, vascular, neuro, colon, ovarian, breast and prostate cancer, epitheleoid sarcomas, AIDS, adverse angiogenesis, restenosis, amyloidosis, tuberculosis, cardiovascular plaque, vascular plaque, obesity, malaria, and illnesses due to viruses, such as HIV.

Safety systems for vehicles, primarily passenger vehicles, comprising automated systems and methods for preventing entrapment of children, disabled, aged or infirm persons, or pets from being trapped in closed vehicles left in the sun, so that they will not suffocate from the heat. The invention is characterized by use of one or more systems to sense the occupancy state and temperature inside the vehicle passenger or load space, and provide one or more outputs which can selectively be employed to provide interior and exterior warning of a trapped passenger in a dangerously hot car to permit rescue, and/or to activate vehicle electro-mechanical systems to relieve the heat, such as rolling down windows, unlatching seat belts, unlocking doors, starting the car and/or fans or air conditioning systems and the like. The exterior warnings may be any suitable warning, such as sounding the car horn or alarm siren, flashing head, tail or special lights, placing an emergency call via a vehicle dedicated cell phone, CB radio, GPS system, or the like.

A highly palatable and long lasting dog chew for pets has been developed by combining a formulation and processing sequence which results in a highly palatable meat based filling being incorporated into the center of a preformed rawhide stick or rawhide roll. Such outside rawhide fraction is extremely tough and chewy which results in a dog chew which takes a long period of time for the dog to consume. The inside meat filling is highly palatable which results in the animal maintaining interest in the treat until nearly the entire chew has been consumed. The interior meat filling is preserved by reduced water activity to below 0.85 as a result of incorporating of salt, sugars and natural humectants. Said filling is formulated and processed in such a manner that the water phase is bound within the filling and does not pass by capillary action to the outside rawhide fraction. This results in the outer rawhide shell maintaining a tough and chewable texture until such point as the dog is offered the finished chew.

The invention relates to the field of a pet device, and especially relates to an intelligent pet food emitter. The intelligent pet food emitter comprises a matrix, the matrix is internally provided with an emission channel communicating with the outside, the emission channel is straight, the emission channel is internally provided with an impact rod, and a compression spring is arranged between the tail end and of the impact rod and the matrix; and the matrix at the upper end of the emission channel is provided with a food chamber for containing food, a discharge port at the bottom of the food chamber communicates with the emission channel, the matrix is internally provided with a reciprocating motion mechanism, and the reciprocating motion mechanism is connected with the impact rod through a disengagement mechanism. According to the intelligent pet food emitter, through arrangement of a mobile phone APP, real-time distribution of the food can be remotely controlled, the food is thrown to a certain distance by use of the emission channel, interaction fun with a pet can be realized, the pet status can be remotely observed, and remote conversation with the pet can be realized.

A space-efficient substantially transparent mutual capacitance touch sensor panel can be created by forming columns made of a substantially transparent conductive material on one side of a first substantially transparent substrate, forming rows made of the substantially transparent conductive material on one side of a second substantially transparent substrate, adhering the two substrates together with a substantially transparent adhesive, bringing column connections down to the second substrate using vias, and routing both the column and row connections to a single connection area on the second substrate. In addition, in some embodiments some of the row connections can be routed to a second connection area on the second substrate to minimize the size of the sensor panel.

The apparatus and method are designed to compute the optimal spatial and temporal characteristics for combating tumor growth within a body on the basis of cytological (as provided by biopsies, etc.) and anatomical data (as provided by CT, MRI, PET, etc.), as well as the electric properties of the different elements. On the basis of this computation, the apparatus applies the fields that have maximal effect on the tumor and minimal effect on all other tissues by adjusting both the field generator output characteristics and by optimal positioning of the insulated electrodes or isolects on the patient's body.

A method and apparatus for rapidly soliciting the help of nearby people in a crisis situation such as a kidnapping is disclosed. The invention allows a person such as a parent to alert people who are within a specified radius of the person to voluntarily assist in looking for a missing child, pet, elderly person or other party in the area immediately surrounding the site where the party was last seen. The system allows for this assistance to be solicited within seconds of recognition of the fact that the party is missing. The system operates over the public mobile phone network using available location based services (LBS) technology such as those mandated by the FCC for enhanced 911 mobile emergency calls. Users, once notified of the missing child, could log their locations into the system if they spot the child at a specific time after they receive the alert. The resultant child tracking record is reported to the initial caller periodically by mobile. In addition, local “hot spot” wireless networks based at retail stores, museums, amusement parks etc can also be used to specify the users' location. The alert signal received from a particular wireless hot point in a retail store, for example, would initiate a request for help in searching for the missing person to be broadcast to the same hot point in the same retail store or nearby hotspots over a network managed by a wireless hot spot aggregator or a wireless carrier.

Rather than trying to immobilize a living, moving organ to place the organ in the fixed frame of reference of a table-mounted robotic device, the present disclosure teaches mounting a robot in the moving frame of reference of the organ. That task can be accomplished with a wide variety of robots including a miniature crawling robotic device designed to be introduced, in the case of the heart, into the pericardium through a port, attach itself to the epicardial surface, and then, under the direct control of the surgeon, travel to the desired location for treatment. The problem of beating-heart motion is largely avoided by attaching the device directly to the epicardium. The problem of access is resolved by incorporating the capability for locomotion. The device and technique can be used on other organs and on other living bodies such as pets, farm animals, etc. Because of the rules governing abstracts, this abstract should not be used in construing the claims.

The present invention discloses a system and a method to locate moving objects, such as people, pets and vehicles, over a wide area, by attaching small wireless devices, such as Bluetooth transceivers, to said objects and determining the location of said devices. The location of said wireless devices is determined by achieving ad-hoc short range wireless connectivity between said devices and communication devices such as Bluetooth enabled mobile phones that pass by, where said latter communication devices can be located by other means, such as GPS or network-based techniques.

A method of selectively removing fluorocarbon layers from overlying low-k dielectric material is described. These protective plasma treatments (PPT) are delicate alternatives to traditional post-etch treatments (PET). The method includes sequential exposure to (1) a local plasma formed from a silicon-fluorine precursor followed by (2) an exposure to plasma effluents formed in a remote plasma from a fluorine-containing precursor. The remote plasma etch (2) has been found to be highly selective of the residual material following the local plasma silicon-fluorine exposure. The sequential process (1)-(2) avoids exposing the low-k dielectric material to oxygen which would undesirably increase its dielectric constant.

Compounds of Formula I-a

and all pharmaceutically-acceptable forms thereof, are described herein.

The variables R₁, R₂, R₃, Z₁, Q, and A shown in Formula I-a are defined herein. Pharmaceutical compositions containing one or more compounds of Formula I-a, or a pharmaceutically acceptable form of such compounds, and one or more pharmaceutically acceptable carriers, excipients, or diluents are provided herein. Methods of treating patients suffering from certain diseases responsive to inhibition of tyrosine kinase activity are also given. In certain embodiments the diseases are responsive to inhibition of Btk activity and/or B-cell proliferation. Such methods comprise administering to such patients an amount of a compound of Formula I-a effective to reduce signs or symptoms of the disease. These diseases include cancer, an autoimmune and/or inflammatory disease, or an acute inflammatory reaction. Thus methods of treatment include administering a sufficient amount of a compound or salt as provided herein to decrease the symptoms or slow the progression of these diseases. Other embodiments include methods of treating other animals, including livestock and domesticated companion animals, suffering from a disease responsive to inhibition of kinase activity. Methods of treatment include administering a compound of Formula I-a as a single active agent or administering a compound of Formula I-a in combination with one or more other therapeutic agent. A method for determining the presence of Btk in a sample, comprising contacting the sample with a compound or form thereof of Formula I-a under conditions that permit detection of Btk activity, detecting a level of Btk activity in the sample, and therefrom determining the presence or absence of Btk in the sample.

The invention relates to an intelligent and automatic delineation method for a gross tumor volume and organs at risk, which includes the following steps: (1) tumor multi-modal (mode) image reconstruction, de-noising, enhancement, registration, fusion and other preprocessing; (2) automatic extraction of tumor image features: automatically extracting one or more pieces of tumor image group (texture feature spectrum) information from CT, CBCT, MRI, PET and/or ultrasonic multi-modal (mode) tumor medical image data; and (3) intelligently and automatically delineating a gross tumor volume and organs at risk through deep learning, machine learning, artificial intelligence, regional growing, the graph theory (random walk), a geometric level set, and/or a statistical theory method. A gross tumor volume (GTV) and organs at risk (OAR) can be delineated with high precision.

The invention consists in structuring scintillation radiation detectors as Photonic Bandgap Crystals or 3D layers of thin filaments, thus enabling extremely high spatial resolutions and achieving virtual voxellation of the radiation detector without physical separating walls. The ability to precisely measure the recoil electron track in a Compton camera enables to assess the directions of the gamma rays hitting the detector and consequently dispensing with collimators that strongly reduce the intensity of radiation detected by gamma cameras. The invention enables great enhancements of the capabilities of gamma cameras, SPECT, PET, CT and DR machines as well as their use in Homeland Security applications. Methods of fabrication of such radiation detectors are decribed.

Image data obtained by image-capturing by a pet robot is stored in a memory, and any of conditions whether the memory capacity is scarce, a captured image transfer instruction is made, or the battery capacity of the pet robot is scarce is satisfied, the pet robot is controlled to move to the charging apparatus. When the pet robot arrives at the charging apparatus, the image data is transferred to the charging apparatus. When the completion of transfer of the image data is detected, the image data already transferred is erased depending upon selection by the user.

Embodiments of the invention relate to omni-tomographic imaging or grand fusion imaging, i.e., large scale fusion of simultaneous data acquisition from multiple imaging modalities such as CT, MRI, PET, SPECT, US, and optical imaging. A preferred omni-tomography system of the invention comprises two or more imaging modalities operably configured for concurrent signal acquisition for performing ROI-targeted reconstruction and contained in a single gantry with a first inner ring as a permanent magnet; a second middle ring containing an x-ray tube, detector array, and a pair of SPECT detectors; and a third outer ring for containing PET crystals and electronics. Omni-tomography offers great synergy in vivo for diagnosis, intervention, and drug development, and can be made versatile and cost-effective, and as such is expected to become an unprecedented imaging platform for development of systems biology and modern medicine.

Devices, systems, and methods for responding to emergency situations of infants, children and pets left unattended in a vehicle. The device comprises a control module for short range RF transmission housed in a lightweight, portable unit plugged into a vehicle accessory power outlet. The system may additionally comprise sensors in communication with the module to detect and trigger alarms, including: when a vehicle has been in a collision; whether a child has climbed out of a car seat while the vehicle is in motion; when the temperature within the vehicle is unsafe; whether an infant has been left unattended in a vehicle; and whether children are playing in a parked vehicle (e.g. trunk) in unsafe temperatures. The portable device may also be configured with an “SOS” button housed within a key fob, wristband, or necklace, to transmit GPS coordinates of the wearer in emergency situations (such as kidnappings).

The present invention relates to identification documents and smart cards. In one implementation, we provide a smart identification document including a document core. The document core is printed and laminated. The laminated core is milled to create a cavity. An integrated circuitry module is provided in the cavity. In one implementation, the cavity includes an upper cavity and a lower cavity. A laminate layer houses the upper cavity while the lower cavity extends into the document core. The upper cavity's aperture exceeds the aperture of the lower cavity resulting in a ledge in the laminate layer. A portion of the module may rest on the ledge, while another portion of the module may extend into the lower cavity. In another implementation, we provide a contactless smart card including a multi-layered structure. The structure includes a carrier layer including the smart card electronics. The carrier can be permeable (like a mesh or scrim) so that additional layers may be laminated into or through the carrier layer. A multi-layer structure provides a enhanced durability and helps protect the smart card electronics. In still another implementation, we provide a PET-based identification document. The PET-based document includes favorable durability and earth-friendly characteristics.

A wireless operating system (10) utilizing a multi-functional wall station (12) for a motorized door/gate operator includes an operator (50) for controlling the movement of a door/gate (54) between various positions. The system has an operator with a receiver (56) and a wall station transmitter (12) for transmitting a signal (42) to the receiver. The signal initiates separate operator functions in addition to opening and closing of the door/gate. A remote transmitter (70) may send a remote signal (74) received by the receiver, wherein the receiver is capable of distinguishing between the wall station signal (42) and the remote signal (74). The wall station includes a transmitter programming button (24), wherein actuation of the transmitter programming button places the wall station transmitter in a learn mode, and wherein subsequent actuation of the remote transmitter positively identifies the remote transmitter for use with the wall station. A light (66) powered by the operator and a light actuation button (18) provided by the wall station transmitter is included in the system. Actuation of the light actuation button (18) functions to switch the light on or off. A pet height button (22), provided by the wall station transmitter, selectively positions the height of the gate/door (54) from its fully closed position to allow ingress and egress of a pet. A delay-close button (20) closes the door/gate after a predetermined period of time. Actuation of a door installation button (28) sequences the door/gate and said operator through various operational parameters to establish a door operating profile. A keyless entry transmitter (80) and a second wall station may also control the operator.