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31 results about "Colon polyps" patented technology

Fleshy growths on the inside the large intestine.

Method for the early detection of breast cancer, lung cancer, pancreatic cancer and colon polyps, growths and cancers as well as other gastrointestinal disease conditions and the preoperative and postoperative monitoring of transplanted organs from the donor and in the recipient and their associated conditions related and unrelated to the organ transplantation

A method for the early diagnosis of breast, lung, pancreatic and colon growths and cancers as well as conditions associated with donor and recipient organ transplants, both before and after transplantation to identify and allow treatment of possible transplanted organ rejection and other disease conditions related and unrelated to the transplantation, compares the gene expression patterns from a patient's peripheral blood monocytes-lymphocyte's gene system with either the similar gene expression patterns of a normal person, or with the similar gene expression patterns of a person known to have the condition being screened for. Differences between the patient's gene expression patterns for particular genes and the normal patterns indicates the presence of the condition with the number of differences indicating the probability of the condition. Similarities between the patient's gene expression patterns for those particular genes and the patterns of a person known to have the condition indicates the presence of the condition with the number of similarities indicating the probability of the condition. For example, particular genes for use in identifying pancreatic cancer are disclosed.
Owner:BAUER A ROBERT

CT colonography system

A method and system of CT colonography is presented that includes the acquisition of energy sensitive or energy-discriminating CT data from a colorectal region of a subject. CT data is acquired and decomposed into basis material density maps and used to differentiate and enhance contrast between tissues in the colorectal region. The invention is particularly applicable with the detection of colon polyps without cathartic preparation or insufflation of the colorectal region. The invention is further directed to the automatic detection of colon polyps.
Owner:GENERAL ELECTRIC CO

Heat diffusion based detection of structures of interest in medical images

A method for detecting and identifying structures of interest such as colonic polyps or similar structures like lung nodules in volumetric (medical) images data is provided. The method includes obtaining a heat diffusion field (HDF) by applying a heat diffusion scheme to a volume of interest that includes structures. The obtained heat diffusion field is then used for identifying a structure of interest from the structures in the volume of interest using a geometrical analysis of the heat diffusion field. The heat diffusion scheme is, at least partly, governed by non-linear diffusion parameters. The identification includes two parts: (i) the computation of a spherical symmetry parameter, and (ii) the performance of a local analysis of the volume of interest and computation of a triangulization parameter.
Owner:THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIV

Methods of diagnosing and prognosing colonic polyps

InactiveUS20120309697A1Increased likelihood of deathPeptide/protein ingredientsMuscular disorderColorectal PolypAdenocarcinoma polyps
Methods of diagnosing or prognosing a disease or condition associated with increased or over expression of macrophage inhibitory cytokine-1 (MIC-1) are disclosed. The methods typically involve detecting a change in the amount of MIC-1 in a test body sample from a subject taken at two or more timing points. The change in the amount of MIC-1 may be adjusted for the effect of at least the following factors as appropriate: the gender of the subject, the age of the subject, the body mass index (BMI) of the subject, the subject being a smoker, the subject being a user of NSAIDs, and the waist-to-hip ratio where the subject is female. The methods are particularly suitable for diagnosing or prognosing the presence of one or more colorectal polyp(s).
Owner:ST VINCENTS HOSPITAL SYDNEY +1

Method and system for wavelet based detection of colon polyps

A method of identifying colon polyps in a digital volume, wherein the volume includes a plurality of values corresponding to a domain of points in a 3D space, is provided. The method includes selecting a mother wavelet scaling function that corresponds to a polyp; performing a forward wavelet transformation on the volume to obtain a set of wavelet coefficients, wherein each wavelet coefficient is associated with a length scale; determining, for each length scale, a transformation magnitude; and forming, for each length scale, a transformed set of wavelet coefficients associated with the length scale. An inverse wavelet transform is performed on the transformed wavelet coefficients for each length scale to obtain a reconstructed volume, and the reconstructed volume is analyzed for the existence of polyps.
Owner:SIEMENS MEDICAL SOLUTIONS USA INC

Virtual colonoscopy via wavelets

Various techniques can be used to improve classification of colon polyps candidates found via computed tomographic colonography computer aided detection (CTCCAD). A polyp candidate can be classified as a true positive or a false positive. For example, a two-dimensional projection image of the polyp can be generated from a three-dimensional representation and classified based on features of the projection image. An optimal viewpoint for the projection image can be found via techniques such as maximizing viewpoint entropy. Wavelet processing can be used to extract features from the two-dimensional projection image. Feature extraction can use a piecewise linear orthonormal floating search for locating most predictive neighbors for wavelet coefficients, and support vector machines can be employed for classification. The techniques can be useful for improving accuracy of CTCCAD techniques.
Owner:US DEPT OF HEALTH & HUMAN SERVICES

Method and system for using structure tensors to detect lung nodules and colon polyps

A method of identifying spherical objects in a digital image is provided. The image comprises a plurality of 3D surface points. The method includes computing, at each point in a domain of the image, a gradient of the image; computing an elementary structure tensor at each point in the domain of the image; determining a structure tensor for each point in the domain of the image; finding the eigenvalues of the structure tensors; and calculating an isotropy measure for each structure tensor, wherein said isotropy measure is defined by a ratio of a smallest eigenvalue of said structured tensor by a largest eigenvalue of said structure tensor, wherein a spherical object correspond to an isotropy measure equal to unity.
Owner:SIEMENS MEDICAL SOLUTIONS USA INC

Deep learning for real-time colon polyp detection

ActiveUS20210133964A1Reduce false positive falseReduce false false negativeImage enhancementDetails involving processing stepsPattern recognitionIntestinal polyp
A set of enhancements to further improve the performance of deep learning artificial intelligence algorithms trained to detect and localize colon polyps. The enhancements spanning training data mining efficiencies and automation, training data augmentation, early detection of polyps enable a more performant colon polyp detection solution for use on colonoscopy procedure recordings or live procedures in endoscopy centers.
Owner:ENDOVIGILANT INC

Method for the early detection of breast cancer, lung cancer, pancreatic cancer and colon polyps, growths and cancers as well as other gastrointestinal disease conditions and the preoperative and postoperative monitoring of transplanted organs from the donor and in the recipient and their associated conditions related and unrelated to the organ transplantation

A method for the early diagnosis of breast, lung, pancreatic and colon growths and cancers as well as conditions associated with donor and recipient organ transplants, both before and after transplantation to identify and allow treatment of possible transplanted organ rejection and other disease conditions related and unrelated to the transplantation, compares the gene expression patterns from a patient's peripheral blood monocytes-lymphocyte's gene system with either the similar gene expression patterns of a normal person, or with the similar gene expression patterns of a person known to have the condition being screened for. Differences between the patient's gene expression patterns for particular genes and the normal patterns indicates the presence of the condition with the number of differences indicating the probability of the condition. Similarities between the patient's gene expression patterns for those particular genes and the patterns of a person known to have the condition indicates the presence of the condition with the number of similarities indicating the probability of the condition. For example, particular genes for use in identifying pancreatic cancer are disclosed.
Owner:BAUER A ROBERT

Narrow-band imaging detection method in colonoscope operation based on image recognition

The invention discloses a narrow-band imaging detection method in a colonoscope operation based on image recognition. The method comprises the following steps: detecting a colonoscope video through abuilt colonoscope polyp detection and recognition model, and judging whether polyps exist or not; and if the polyps are detected, judging the relationship between an R channel average value of intestinal images and a threshold value by utilizing an OpenCV image processing technology, and giving a prompt of whether NBI observation needs to be carried out or not according to the relationship betweenthe R channel average value of the intestinal images and the threshold value. The method is used for detecting colonic polyps in real time; when polyps are found, whether an operator observes the polyps through the NBI technology or not is judged through the OpenCV image processing technology; and if not, a prompt is given to standardize the operation method of the operator, so the missed diagnosis rate of polyps is reduced to the maximum extent, and therefore, the death rate of patients is reduced.
Owner:杨国珍

Method for diagnosing colon tumor via bacterial metagenomic analysis

The present invention relates to a method for predicting the incidence of a colon tumor, such as a colon polyp and colon cancer, and a causative factor thereof through metagenomic analysis of a bacterium-derived vesicle present in a human body-derived substance. More particularly, the present invention relates to a method for diagnosing a causative factor of a colon tumor and the risk of the incidence thereof by sequencing a metagenome present in a bacterium-derived vesicle present in excrement or urine. There are trillions of bacteria in an intestine, and the bacteria secrete vesicles out ofthe cells thereof for the purpose of information exchange. The bacteria are not absorbed into epithelial cells in a colon, but the vesicles secreted therefrom pass through the mucous membrane, are absorbed into the colonic epithelial cells, are distributed throughout the body via blood, and then are excreted through a liver and a kidney. The bacteria-derived vesicles may increase or decrease the occurrence of inflammation and cancer, and the present invention can be useful as a method for diagnosing the risk of the incidence of a colon tumor or a causative factor thereof by sequencing a genetic metagenome of a bacterium-derived vesicle present in a human body-derived substance. Further, an early diagnosis can still be made even after the incidence of a colon polyp or the onset of colon cancer, and the incidence of colon cancer can be lowered, and the treatment effect can be enhanced.
Owner:MD HEALTHCARE INC

Methods and nucleic acids for the analysis of colorectal cell proliferative disorders

Various aspects of the present invention provide novel diagnostic and prognostic methods for detecting, or for detecting and differentiating between or among colorectal cell proliferative disorders. Preferably, said colorectal cell proliferative disorders are selected from the group consisting of colorectal carcinoma, colon adenomas, and colon polyps. The inventive methods are based on analysis of differential CpG dinucleotide methylation of genomic DNA between or among normal and disease states. Additional embodiments provide nucleic acids and oligomers (including oligonucleotides and peptide nucleic acid (PNA)-oligomers), nucleic acid arrays and kits useful for practicing said methods, and in otherwise detecting, or detecting and differentiating between or among colorectal cell proliferative disorders.
Owner:EPIGENOMICS AG

Colon polyp image data processing method based on virtual colonoscopy

The invention discloses a colon polyp image data processing method based on virtual colonoscopy. The method comprises the following steps performed in a graphics processor: S1, collecting 3D image data of a colon part, carrying out image preprocessing on the image data to get a fitted contour surface of the colon wall, and selecting W seed points reflecting the characteristics of colon polyps from the fitted contour surface; S2, gradually moving the seed points, and shadowing the moved seed points onto a real contour surface of the image, and forming W curvature lines; S3, spreading the curvature lines and generating a curvature line set; and S4, screening out characteristic curvature lines reflecting the shape characteristics of colon polyps from the curvature line set, and drawing the characteristic curvature lines onto the fitted contour surface to highlight a colon polyp. The technical problem that the overall three-dimensional shape characteristics of polyps cannot be described accurately in the prior art is solved.
Owner:SUZHOU INST OF BIOMEDICAL ENG & TECH CHINESE ACADEMY OF SCI

Assessing and treating mammals having polyps

PendingUS20200263258A1Increased riskEnhance diagnosis and risk assessment and managementMicrobiological testing/measurementHeavy metal compound active ingredientsBiologyGastroenterology
This document relates to methods and materials for assessing and / or treating mammals (e.g., humans) having one or more polyps (e.g., one or more colon polyps). For example, this document provides methods and materials for determining if a polyp (e.g., a polyp within a mammal having one or more polyps) is likely to recur and / or likely to progress to a cancer. This document also provides methods and materials for treating a mammal having one or more polyps.
Owner:MAYO FOUND FOR MEDICAL EDUCATION & RES

Colon polyp image processing method and apparatus, and system

A colon polyp image processing method and apparatus and a system are disclosed in the embodiments of this application to detect a position of a polyp in real time and determine a property of the polyp, and thereby improve the processing efficiency of a polyp image. Embodiment of this application provide a colon polyp image processing method that can include detecting a position of a polyp in a to-be-processed endoscopic image by using a polyp positioning model, and positioning a polyp image block in the endoscopic image. The polyp image block can include a position region of the polyp in the endoscopic image. The method can further include performing a polyp type classification type on the polyp image block by using a polyp property identification model, and outputting an identification result.
Owner:TENCENT TECH (SHENZHEN) CO LTD

Compositions and methods for treating inflammatory bowel disease and fusobacteria-caused or related diseases and conditions

Provided herein are pharmaceutical compositions, therapeutic combinations, devices and methods for treating, ameliorating, reversing, causing the remission of, and / or preventing (acting as a prophylaxis, or preventing the initiation of) an inflammatory bowel disorder (IBD) or inflammatory bowel disease (IBD), Ulcerative Colitis; Crohn's disease; J-pouch; fistulising Crohn's disease; a Colitis which can be microscopic, lymphocytic or collagenous; an eosinophilic colitis; indeterminate colitis; idiopathic colitis; diverticulosis and diverticulitis; relapsing diverticulitis; constipation associated inflammatory bowel disease and / or small intestinal bacterial overgrowth; Irritable Bowel Syndrome (IBS) with or without diarrhoea, constipation or pain predominant IBS; periodontitis; rheumatoid arthritis; respiratory infections, appendicitis, vascular disorders such as thrombophlebitis; bacteremia; osteomyelitis; septic shock; Alzheimer's disease; Lemierre syndrome (postanginal sepsis); colonic polyps or adenomas (optionally hyperplastic, adenomatous or serrated adenomas) or preventing the growth of colonic polyps or adenomas, bowl cancer, or metastases (optionally preventing the initiation or promotion of bowl cancer or metastasis); pharyngitis; otitis; sinusitis; and any disease, symptom or condition caused or exacerbated by a Fusobacteria (optionally, a F. nucleatum or F. varium) infection. In alternative embodiments, pharmaceutical compositions comprise rifaximin alone or in combination with other antibiotics or drugs.
Owner:托马斯·朱利叶斯·波洛迪

Colon image recognition method and device and related equipment

The invention discloses a colon image recognition method. The method comprises the steps of obtaining a to-be-detected colon image; detecting the colon image to be detected through a single-target detector to obtain a first detection result; wherein the detection target of the single-target detector is polyp tissue; detecting the colon image to be detected through a multi-target detector to obtaina second detection result; wherein the detection target of the multi-target detector comprises polyp tissue and interference tissue; determining polyp information in the colon image to be detected according to the first detection result and the second detection result. The colon image recognition method can effectively improve the accuracy of colon polyp recognition. The invention further discloses a colon image recognition device, colon image recognition equipment and a computer readable storage medium, which all have the above beneficial effects.
Owner:浙江核睿医疗科技有限公司

Traditional Chinese medicine composition for treating intestinal polyps

The invention provides a traditional Chinese medicine composition for treating intestinal polyps. The traditional Chinese medicine composition is prepared from, by weight, 5-10 parts of nodus nelumbinis rhizomatis, 5-10 parts of fructus mume, 5-15 parts of bombyx batryticatus, 1-5 parts of alumen, 1-5 parts of dried alum, 5-10 parts of bile, 20-40 parts of fructus mume preparata, 2-10 parts of rhizoma coptidis, 6-15 parts of stir-baked amur cork tree bark, 3-10 parts of aconitum carmichaeli debx, 2-10 parts of baked ginger, 3-12 parts of ramulus cinnamomi, 2-10 parts of herbal asari, 2-10 parts of dried peel of zanthoxylum schinifolium or zanthoxylum bungea, 3-15 parts of stir-baked radix codonopsis, 9-15 parts of radix angelica sinensis, 9-30 parts of rhizoma curcumae, 3-12 parts of stir-baked squama manitis, 9-15 parts of radix aucklandiae, 9-15 parts of semen arecae and 20-50 parts of all-grass of patrinia scabiosaefolia. The traditional Chinese medicine composition can be used for preparing medicine for treating colon polyps and rectal polyps and has the advantages of removing slough and promoting growth of tissue regeneration, cooling blood, stopping bleeding, stopping pain, taking effect quickly and being capable of achieving radical treatment and the like.
Owner:刘黎明

Compositions and methods for treating inflammatory bowel disease and fusobacteria-caused or related diseases and conditions

Provided herein are pharmaceutical compositions, therapeutic combinations, devices and methods for treating, ameliorating, reversing, causing the remission of, and / or preventing (acting as a prophylaxis, or preventing the initiation of) an inflammatory bowel disorder (IBD) or inflammatory bowel disease (IBD), Ulcerative Colitis; Crohn's disease; J-pouch; fistulising Crohn's disease; a Colitis which can be microscopic, lymphocytic or collagenous; an eosinophilic colitis; indeterminate colitis; idiopathic colitis; diverticulosis and diverticulitis; relapsing diverticulitis; constipation associated inflammatory bowel disease and / or small intestinal bacterial overgrowth; Irritable Bowel Syndrome (IBS) with or without diarrhoea, constipation or pain predominant IBS; periodontitis; rheumatoid arthritis; respiratory infections, appendicitis, vascular disorders such as thrombophlebitis; bacteremia; osteomyelitis; septic shock; Alzheimer's disease; Lemierre syndrome (postanginal sepsis); colonic polyps or adenomas (optionally hyperplastic, adenomatous or serrated adenomas) or preventing the growth of colonic polyps or adenomas, bowl cancer, or metastases (optionally preventing the initiation or promotion of bowl cancer or metastasis); pharyngitis; otitis; sinusitis; and any disease, symptom or condition caused or exacerbated by a Fusobacteria (optionally, a F. nucleatum or F. varium) infection. In alternative embodiments, pharmaceutical compositions comprise rifaximin alone or in combination with other antibiotics or drugs.
Owner:BORODY THOMAS JULIUS

Colon-released preparation of Melocicon and beta-cyclodextrin or its derivative composition

The invention relates to capsules, matrix tablets and micropill preparations for colon-localized release of meloxicam / β-cyclodextrin or derivatives thereof. The preparation utilizes the principle that the colonic flora can degrade the polysaccharide cyclodextrin, combined with the pH-sensitive coating material or carrier, enables the drug preparation to achieve the precise positioning effect of specific release in the colon, and solves the problem of the drug before reaching the colon. The problem of burst release and the problem of rapid release in the mucous environment of the colon. The preparation of the invention is beneficial to the treatment of meloxicam on local diseases of the colon, such as ulcerative colitis, colon cancer, colon polyps and the like.
Owner:INST OF PHARMACOLOGY & TOXICOLOGY ACAD OF MILITARY MEDICAL SCI P L A
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