This invention belongs to the field of functional
probiotic screening and application technology, specifically involving a novel strain of *
Lactobacillus plantarum* (…). Lactiplantibacillus plantarum The *
Lactobacillus plantarum* strain was deposited on January 15, 2026, at the China Center for Type Culture Collection (CCTCC), Wuhan University, Wuhan, China, with accession number CCTCC NO: M202026133. This strain exhibits strong
antioxidant capacity, significant inhibitory and flocculating effects against hemolytic streptococci, and can significantly reduce the levels of pro-inflammatory cytokines IL-6 and IL-1β induced by hemolytic streptococci while increasing the level of the anti-inflammatory
cytokine IL-22. It has no toxic effects on the body, good
safety profile, and can be used to prevent colonic polyps and colon
cancer caused by hemolytic streptococci, showing broad application prospects.