36 results about "Virtual colonoscopy" patented technology

A system for performing a virtual colonoscopy includes a system for generating digital images, a storage device for storing the digital images, a digital bowel subtraction processor coupled to receive images of a colon from the storage device and for removing the contents of the colon from the image and an automated polyp detection processor coupled to receive images of a colon from the storage device and for detecting polyps in the colon image.

A system, method, software arrangement and computer-accessible medium for performing electronic cleansing of CT colonography images are provided. In this system, method, software arrangement and computer-accessible medium, the digital bowel cleansing can be performed to remove tagged bowel contents from the images. The digital bowel cleansing can apply a local shape analysis throughout the images and use a shape-based speed function to detect the folds and polyps structures while removing the tagged bowel contents region. The system, method, software arrangement and computer-accessible medium can enable a medical examiner to perform an accurate virtual colonoscopy on a patient, without the need for thorough patient preparation.

An ingestible pill platform for colon imaging is provided, designed to recognize its entry to the colon and expand in the colon, for improved imaging of the colon walls. On approaching the external anal sphincter muscle, the ingestible pill may contract or deform, for elimination. Colon recognition may be based on a structural image, based on the differences in diameters between the small intestine and the colon, and particularly, based on the semilunar fold structure, which is unique to the colon. Additionally or alternatively, colon recognition may be based on a functional image, based on the generally inflammatory state of the vermiform appendix. Additionally or alternatively, pH, flora, enzymes and (or) chemical analyses may be used to recognize the colon. The imaging of the colon walls may be functional, by nuclear-radiation imaging of radionuclide-labeled antibodies, or by optical-fluorescence-spectroscopy imaging of fluorescence-labeled antibodies. Additionally or alternatively, it may be structural, for example, by visual, ultrasound or MRI means. Due to the proximity to the colon walls, the imaging in accordance with the present invention is advantageous to colonoscopy or virtual colonoscopy, as it is designed to distinguish malignant from benign tumors and detect tumors even at their incipient stage, and overcome blood-pool background radioactivity.

The present invention provides agents and methods for dual modality virtual colonoscopy that gives both anatomical and functional information using hybrid CT / PET scanning. In preferred embodiments, the present invention provides radiolabeled tumor-specific agents and methods for distinguishing benign polyps from malignant tumors. In further embodiments, the present invention provides compositions and methods useful for distinguishing morphological and functional subregions of a selected region of tissue based on relative levels of phospholipid metabolism. Preferred radiolabeled tumor-specific agents are phospholipid ether analogs labeled with a halogen radioisotope. In certain preferred embodiments, the compositions including radiolabeled phospholipid ether analogs have therapeutic actions in addition to functionally identifying malignant tissue.

An embodiment of the invention is method, which can be implemented in software, firmware, hardware, etc., for virtual fly over inspection of complex anatomical tubular structures. In a preferred embodiment, the method is implemented in software, and the software reconstructs the tubular anatomical structure from a binary imaging data that is originally acquired from computer aided tomography scan or comparable biological imaging system. The software of the invention splits the entire tubular anatomy into exactly two halves. The software assigns a virtual camera to each half to perform fly-over navigation. Through controlling the elevation of the virtual camera, there is no restriction on its field of view (FOV) angle, which can be greater than 90 degrees, for example. The camera viewing volume is perpendicular to each half of the tubular anatomical structure, so potential structures of interest, e.g., polyps hidden behind haustral folds in a colon are easily found. The orientation of the splitting surface is controllable, the navigation can be repeated at another or a plurality of another split orientations. This avoids the possibility that a structure of interest, e.g., a polyp that is divided between the two halves of the anatomical structure in a first fly over is missed during a virtual inspection. Preferred embodiment software conducts virtual colonoscopy fly over. Experimental virtual fly over colonoscopy software of the invention that performed virtual fly over on 15 clinical datasets demonstrated average surface visibility coverage is 99.59+ / −0.2%.

Embodiments of the invention provide a system and method for using an electro-pneumatic insufflator for magnetic resonance imaging, such as for virtual colonoscopy. Embodiments of the invention further provide a MRI imaging suite and a method for distension of a body part to be imaged. As an alternative to the complete redesign of an electro-magnetic insufflator, embodiments of the current invention utilize a standard electro-pneumatic insufflator that operates in a location impervious to electromagnetic radiation using an electromagnetically inactive connection tube.

A method for determining an estimation of a topological support of a tubular based structure comprising an inner wall and a plurality of distinct regions, the method comprising (a) obtaining image data representative of the tubular based structure; (b) placing an initial seed in an initial region selected from one of the distinct regions; (c) performing an initial region growing until an initial resulting area comprises at least a portion of the inner wall and at least a portion of a neighboring region corresponding to one of the distinct regions; (d) starting a tree comprising an initial tree node corresponding to the initial region; (e) for each neighboring region: placing a subsequent seed in the neighboring region; performing a corresponding subsequent region growing until a subsequent resulting area comprises at least a portion of the inner wall and at least a portion of an additional neighboring region; and adding a tree node corresponding to the neighboring region in the tree; (f) performing processing step (e) for each of the additional neighboring regions; and (g) filtering the tree according to predetermined topological parameters to thereby determine the estimation of the topological support of the tubular based structure. Applications of the method for estimating a colon topology for virtual colonoscopy are also disclosed.

A method for automatic virtual endoscopy navigation, including: (a) using a fisheye camera to generate an endoscopic image and a depth image from a current position of the camera in lumen computed tomographic (CT) data; (b) segmenting a first region and a second region from the depth image, wherein the first region identifies a view direction of the camera and the second region is an area through which the camera can be moved without touching an inner surface of the lumen; (c) moving the camera from the current position, while pointing the camera in the view direction, to a next position in the second region; and (d) repeating steps (a-c) in sequence using the next position in step (c) as the current position in step (a).