20 results about "Sexual impotence" patented technology

This invention belongs to the field of traditional Chinese medicine, specifically relating to a topical delay spray and its preparation method. The invention uses the dried epidermis of the Huaxi toad (with the toad venom removed), and extracts it efficiently through a combination of water and alcohol extraction. Male silkworm moth oil can nourish and strengthen the body, tonify the liver and kidneys, and combat fatigue; studies have shown that male silkworm moth oil can effectively treat kidney yang deficiency. This invention combines the synergistic effects of toad skin extract and male silkworm moth oil to prepare a delay spray that can significantly treat premature ejaculation and erectile dysfunction in men. This preparation has the advantages of direct action, sustained release, avoidance of drug contact, and simple operation. This invention further improves the rational utilization system of toad resources, provides a practical solution for the efficient development of toad medicinal resources, and significantly reduces production and clinical application costs.

The present invention relates to a crystalline form I represented by Formula 1, which may be characterized by XRD patterns, DSC profiles, and / or TGA profiles, a method for preparing the same, and a pharmaceutical composition comprising the same, useful for the treatment of prevention of obesity, diabetes, inflammation, or erectile dysfunction. (see formula 1) wherein R1 is C2-C5 alkyl.

This invention discloses a traditional Chinese medicine composition for erectile dysfunction due to deficiency of both heart and spleen, and its application, belonging to the field of traditional Chinese medicine technology. The composition consists of a basic formula and modified formulas. The basic formula includes a spleen-tonifying and qi-boosting group, a heart-nourishing and blood-nourishing group, and a blood-activating and aphrodisiac group. The modified formulas are adjusted according to different concurrent symptoms. It can be prepared into various dosage forms such as decoctions and granules. This traditional Chinese medicine composition precisely addresses the core pathogenesis of erectile dysfunction due to deficiency of both heart and spleen—namely, "insufficient heart blood, deficiency of spleen qi, and malnourishment of the reproductive organs"—achieving spleen-tonifying and heart-nourishing, qi-boosting and blood-nourishing, and blood-activating and aphrodisiac effects, without causing stagnation or greasiness. Clinical trials have demonstrated definite efficacy, high overall effective rate, few adverse reactions, and low long-term recurrence rate. It can comprehensively improve patients' erectile function and accompanying symptoms, and is suitable for preparing drugs to treat erectile dysfunction due to deficiency of both heart and spleen.

This invention relates to a restraint-free wearable intelligent sensing device and method for patients with erectile dysfunction (ED), belonging to the field of medical monitoring equipment and technology. The device includes an underwear-like main structure, a data acquisition unit, a micro-control module, a power supply module, and an electrical stimulation module. The underwear-like main structure has a data acquisition and monitoring area composed of multiple annular fiber sensing units arranged in a columnar elephant trunk structure. Each annular fiber sensing unit has an independent pressure-sensitive fiber sensing module. The data acquisition unit collects the wearer's pressure and temperature data in real time. The micro-control module is connected to the data acquisition unit to process and transmit the data collected. The method employs a multi-sensor signal processing stage algorithm and a cloud-based monitoring and closed-loop control stage algorithm. Based on the acquired loop-level monitoring data, it provides real-time feedback and prompts for adjustments, improving treatment convenience and personalization, and providing a more comprehensive, precise, and restraint-free solution for ED monitoring.

A body implantable reservoir assembly has a reservoir body adapted to contain the liquid and an electronic assembly disposed in the reservoir body and adapted to move the liquid between the reservoir body and an implantable prosthesis. The electronic assembly has a printed circuit board and a battery hermetically sealed inside a canister, a pump assembly having a motor electrically coupled with the printed circuit board and the battery, a pump coupled with the motor, and a valve assembly coupled with the pump. When the reservoir body contains the liquid, the motor, the pump, and the valve assembly are immersed in the liquid.

The application discloses an external use delayed cream with natural ingredients and a preparation method thereof, belongs to the field of traditional Chinese medicine, and particularly relates to an external use delayed cream containing dry toad extract and toad oil and a preparation method thereof. The application is based on the local anesthetic properties of the dry toad extract and the toad oil, and an external use delayed cream is prepared by quantitatively controlling the dosages of the dry toad extract and the toad oil, which is used for treating male premature ejaculation and erectile dysfunction. The preparation has the advantages of direct action, sustained release and simple operation, and the preparation cost is low because the toad killed in breeding is used as a raw material. The application realizes the transformation of toad oil from waste to treasure, fully excavates the medicinal value of the toad oil, further perfects a reasonable utilization system of toad resources, and provides a practical scheme for efficient development of toad medicinal resources.

The application belongs to the field of traditional Chinese medicine, and particularly relates to an external use delayed oil agent and a preparation method thereof. The dried skin of the Visternotus limnocharis which has scraped toad venom is combined with the male silkworm moth which has the functions of tonifying liver and kidney, strengthening yang and astringing essence to significantly improve male premature ejaculation and erectile dysfunction through water extraction and alcohol extraction. The male silkworm moth oil has unique promotion potential and development potential. The application combines the toad skin and the male silkworm moth oil to prepare the delayed oil agent, significantly improves male premature ejaculation and erectile dysfunction, and has the characteristics of direct action and simple operation. The preparation cost is low.

The present application relates to the technical field of medical equipment, and discloses a conformal wireless LIPUS erectile dysfunction treatment device based on a photoacoustic transducer, which comprises a pulsed light source emitter and a photoacoustic conversion composite material, and a use method of the treatment device, which comprises the following steps: uniformly applying the photoacoustic conversion composite material to a penis part of a patient, and allowing the photoacoustic conversion composite material to solidify to form a flexible conformal film layer; turning on the pulsed light source emitter, and irradiating the conformal film layer with far-infrared pulsed light emitted by the pulsed light source emitter; after the conformal film layer absorbs light energy of the far-infrared pulsed light, the light energy is converted into heat energy, then thermal expansion of the conformal film layer is caused, so that LIPUS is generated, and rehabilitation treatment is performed on the penis part of the patient. The present application provides a more portable, more comfortable and lower-cost LIPUS ED treatment device and method, and helps the clinical promotion and market application of LIPUS in the ED treatment field.

The invention provides a novel pharmaceutical composition comprising a phosphodiesterase type 5 (PDE5) inhibitor other than sildenafil and a dopamine agonist and method of use thereof for treating erectile dysfunction and / or male hypogonadism.

Microparticles that contain miRNA that controls the production of nitric oxide and are an agent for promoting the production of nitric oxide are new microparticles that enable controlling the expression of a protein and / or a gene related to erectile dysfunction; a preventive drug or a therapeutic drug for erectile dysfunction; a method for improving erectile dysfunction; it is preferable that the microparticles be exosomes; and it is preferable that the microparticles of the present disclosure contain miRNA targeting a gene concerning the expression of nitric oxide synthase as the miRNA that controls the production of nitric oxide, and be an agent for promoting the expression of nitric oxide synthase.

This invention relates to a novel method for treating erectile dysfunction by injecting an embolic or sclerosing agent into the corpora cavernosa or corpus spongiosum of the penis. The invention also relates to a novel method for treating erectile dysfunction by injecting an embolic or sclerosing agent into one or more veins of the penis, wherein the embolic or sclerosing agent penetrates into the corpora cavernosa or corpus spongiosum.

This invention relates to a men's growth underwear, which adopts an innovative three-dimensional spiral design for the coronal sulcus, combined with 3D three-dimensional tailoring, an innovative buckle design, and an innovative three-dimensional underwear structure design technology. This allows the underwear to be worn comfortably for a long time, and is especially beneficial for men with short penises or phimosis, preventing premature ejaculation, erectile dysfunction, and other conditions that may affect marital happiness.

The present invention relates to a compound or a pharmaceutically acceptable salt thereof for use in the treatment of erectile dysfunction in combination with at least one second erectogenic agent.

The application discloses a kind of oyster-derived bioactive peptides for enhancing male reproductive health, and belongs to the technical field of functional peptides.The peptide product prepared by the method provided in the application has the bioactivity of improving male sperm quality (increasing sperm quantity and survival rate) and erectile dysfunction, and enhancing male reproductive health;It is convenient to eat, has no toxic side effects, and no adverse effects on volunteers and mice involved in the test were observed during the test;The oyster-derived bioactive peptides for enhancing male reproductive health are prepared from high-quality, edible oysters cultured artificially, no toxic and harmful reagents are used in the preparation process, and the added or used components are all beneficial or harmless to the body or components existing in the body / atmosphere, so the safety is very high.

This invention belongs to the field of traditional Chinese medicine, specifically relating to a delay towel containing dried toad extract and toad oil, and its preparation method. Based on the local anesthetic properties of dried toad extract and toad oil, this invention prepares a topical delay cream by quantitatively controlling the dosage of both, for the treatment of premature ejaculation and erectile dysfunction in men. The delay towel prepared by this invention has the advantages of direct action, individual packaging, immediate use, low cost, and minimal volatility of the active ingredients. This invention not only turns toad oil into a valuable resource and fully explores its medicinal value, but also further improves the rational utilization system of toad resources, providing a practical solution for the efficient development of toad medicinal resources.

This invention relates to the field of medical device technology and discloses an external vibration-electric stimulation device for erectile dysfunction (ED), comprising a shell, a fixing chamber fixedly connected to the top of the shell, a flexible heating layer fixedly connected to the inner diameter of the shell, multiple vibration motors fixedly connected inside the flexible heating layer, multiple ultrasonic transducers fixedly connected inside the flexible heating layer, a shape memory alloy support frame disposed within the inner diameter of the flexible heating layer, multiple micro-airbags disposed within the inner diameter of the shape memory alloy support frame, an inner bonding layer fixedly connected between the multiple micro-airbags, and an electrical stimulation electrode and a bioimpedance detection electrode disposed within the inner diameter of the inner bonding layer. By integrating multiple stimulation methods such as vibration stimulation, electrical stimulation, ultrasonic stimulation, and thermotherapy stimulation in the same external stimulation device and its corresponding method, and by having a controller uniformly schedule each stimulation component, multiple stimulation methods can be executed collaboratively in the same stimulation session.

The present invention relates to a novel compound and a use thereof for treatment of dysuria, cough and erectile dysfunction. More specifically, the present invention relates to a novel diphenyl ether derivative compound capable of ameliorating and treating dysuria, cough, and erectile dysfunction related thereto by effectively activating a BKCa channel.

The application belongs to the field of traditional Chinese medicine, and particularly relates to an external use delayed time towel agent and a preparation method thereof. The dried skin of the Chinese toad from which the toad venom has been scraped is selected, water extraction and alcohol extraction are combined, toad skin extract is efficiently extracted, and the toad skin extract is combined with male moth oil to prepare the delayed time towel agent. It is found that through the synergistic effect of the toad skin extract and the male moth oil, male premature ejaculation and erectile dysfunction can be significantly improved, and the synergistic effect of the two is much higher than that of single medicine, the medicinal effect is optimized, the core requirement of clinical application is met, the towel agent is prepared, independent packaging is achieved, and the towel agent has the characteristics of low cost, direct effect, simple operation, and difficulty in drug pollution.

This invention provides a strain of Akkermansia myxophilus ( Akkermansia muciniphila The present invention provides a probiotic preparation comprising the aforementioned Akkermansia myxophilus or its post-genetically modified organism (PGA). The Akkermansia myxophilus or its post-genetically modified organism (PGA) of the present invention can improve vascular endothelial cell function, increase testosterone secretion, and thus improve erectile dysfunction and reproductive capacity. The probiotic preparation of the present invention may comprise the aforementioned Akkermansia myxophilus or its post-genetically modified organism (PGA) and yohimbine. This preparation can improve erectile dysfunction caused by vascular endothelial dysfunction, improve reproductive function in aged mice, and the components in this preparation have a synergistic effect.

The application discloses a ginseng, cistanche and rhizoma polygonati composition with improved erectile dysfunction caused by aging and a preparation method thereof, and belongs to the field of food processing. The preparation method comprises the following steps: (1) sealing the processed product raw material after adjusting the water content of the processed product raw material to 60-80%; (2) carrying out heat preservation on the sealed raw material; (3) taking out the heat preserved raw material and drying the heat preserved raw material until the water content of the heat preserved raw material is reduced to 15-40%; (4) sealing the raw material treated in the step (3) and carrying out heat preservation on the sealed raw material; and (5) taking out the raw material treated in the step (4) and drying the raw material to obtain the processed product. The ginseng, cistanche and rhizoma polygonati raw materials are pretreated to increase the glucose and maltose content in the raw materials, and finally, a functional food ingredient with a total content of AFG and FruArg of 2.5-8% and a mass ratio of AFG to FruArg of 5:1-1:3 is prepared through water content regulation, sealing and heat preservation and the like. The functional food ingredient is verified through experiments and has an obvious effect of improving the erectile dysfunction caused by aging.