52 results about "Parasympathetic nerve" patented technology

A method is provided, including identifying that a subject is at risk of suffering from atrial fibrillation (AF). Responsively to the identifying, a risk of an occurrence of an episode of the AF is reduced by coupling an electrode device to a site of a subject containing parasympathetic nervous tissue; driving, by a control unit, the electrode device to apply an electrical current to the site not responsively to any physiological parameters sensed by any device directly or indirectly coupled to the control unit; and configuring the current to stimulate autonomic nervous tissue in the site. Other embodiments are also described.

A sleep state measuring apparatus includes an autonomic nerve index obtaining unit that obtains a user's autonomic nerve index; and a sleep periodicity index calculating unit that calculates a sleep periodicity index based on a temporal change of the autonomic nerve index and a change in a user's sleeping cycle, wherein the sleep periodicity index indicates whether the user is sleeping or not according to a user's ideal sleeping cycle as an index, or a dominance index calculating unit that calculates a parasympathetic nerve dominance index which shows dominance of a parasympathetic nerve index included in the autonomic nerve index with respect to a sympathetic nerve index included in the autonomic nerve index for a user during sleep.

The invention relates to a method and device for measuring the autonomic nerve heart regulation and control function. The wearable device, an autonomic nerve heart regulation and control function mathematical model and an autonomic nerve heart regulation and control system parameter calculation method are involved in the method. The wearable device is used for measuring motion data, continuous blood pressure and a heart rate value sequence in a human body standing-up or inclining test. The autonomic nerve heart regulation and control function mathematical model is used for quantitatively describing the blood pressure and heart rate regulation and control process in the standing-up process. According to the autonomic nerve heart regulation and control system parameter calculation method, a series of autonomic nerve heart regulation and control system parameters such as pressure sensor sensitivity and sympathetic nerve and parasympathetic nerve activity are solved based on the autonomic nerve heart regulation and control function mathematical model and the continuous blood pressure and the heart rate value sequence measured in the standing-up or inclining test through the wearable device. Autonomic nerve regulation and control disorders are represented by reduction of the pressure sensor sensitivity and reduction of the sympathetic nerve and parasympathetic nerve activity, which are the occurrence origins and independent indexes of many lethal cardiovascular diseases. Quantitative measurement of the pressure sensor sensitivity and the sympathetic nerve and parasympathetic nerve activity is of great significance on effective diagnosis and prevention of cardiovascular diseases, evaluation of treatment effects and recovery of patients.

The invention provides a biological feedback control method and system based on HRV heart rate variability training. The biological feedback control method comprises the steps that S1, mode options of any one or more combinations including a breathing guiding mode, a breathing training mode and a state evaluating mode are provided for a user to select; and S2, a corresponding mode interface is entered according to the selecting operation of the user, and heart rate variability analyzing is conducted on the current user when the user selects the breathing training mode or the state evaluating mode. The biological feedback control method has the advantages that the biological feedback control method is not limited to simple evaluation any longer, by conducting pointed breathing trainings with different rhythms on the user, impaired parasympathetic nerves (or sympathetic nerves) can recover to be balanced, and the purpose of effective preventing or relieving some diseases is achieved.

Methods and devices are provided for inhibiting nerves when activating brown adipose tissue (BAT). In general, a first nerve type (e.g., sympathetic nerves) innervating BAT can be activated while at least one other nerve type (e.g., parasympathetic nerves and/or sensory nerves) innervating BAT is being suppressed. A first neuromodulator (e.g., an electrical signal, a chemical, a light, cooling, etc.) can be applied to activate the first nerve type, and a second neuromodulator can be applied to inhibit the at least one other nerve type. In this way, parasympathetic nerves and/or sensory nerves innervating BAT can be inhibited when activating sympathetic nerves innervating BAT.

A sleepiness judging device for judging a strong sleepiness before a subject comes to doze. Sleepiness judging device (1) is characterized by comprising a sympathetic parameter acquiring unit (2,11) for acquiring a parameter concerning the sympathetic nerve of a subject, a parasympathetic parameter acquiring unit (2, 11, 16) for acquiring a parameter concerning the parasympathetic nerve of the subject, a sympathetic increase judging unit (13, 14) for judging whether or not the magnitude of the sympathetic parameter is larger than a sympathetic threshold, and a sleepiness judging unit (19) forjudging the sleepiness of the subject from the increase/decrease relation between the sympathetic parameter and the parasympathetic parameter if the magnitude of the sympathetic parameter is judged tobe larger than the sympathetic threshold.

A device covering for controlling blood flow includes a cuff configured to be mounted to an extremity of a patient. The cuff includes a plurality of electrodes electrically connectible to a stimulation power supply. Upon receipt of power from the stimulation power supply, the electrodes supply electrical impulses to the anatomical site in order to stem or stop blood flow. In some cases, the stimulation power supply is an interferential therapy power supply, and a pair of electrodes supplies electrical impulses at two different frequencies, the electrical impulses provided at two different frequencies giving rise to at least one beat impulse having an interference frequency. The beat impulse activates the sympathetic nerves to induce vasoconstriction in the local blood vessels. Alternatively, the beat impulse can be programmed to target the parasympathetic nerves if vasodilatation is desired.

Methods and devices are provided for activating brown adipose tissue (BAT) using electrical energy. In general, the methods and devices can facilitate activation of BAT to increase thermogenesis. The BAT can be activated by applying an electrical signal thereto that can be configured to target sympathetic nerves that can directly innervate the BAT. The electrical signal can be configured to target the sympathetic nerves using fiber diameter selectivity. In other words, the electrical signal can be configured to activate nerve fibers having a first diameter without activating nerve fibers having diameters different than the first diameter. Sympathetic nerves include postganglionic unmyelinated, small diameter fibers, while parasympathetic nerves that can directly innervate BAT include preganglionic myelinated, larger diameter fibers. The electrical signal can be configured to target and activate the postganglionic unmyelinated, small diameter fibers without activating the preganglionic myelinated, larger diameter fibers.

The invention provides a pharmaceutical composition preparation. The pharmaceutical composition preparation comprises an anticholinergic drug tiotropium or a hydrate thereof, a beta 2-receptor agonistarformoterol or a salt thereof, and an inhaled glucocorticoid fluticasone or an ester derivative thereof; tiotropium bromide acts on a muscarinic receptor on bronchial smooth muscles, the cholinergiceffect of acetylcholine released by the tail ends of parasympathetic nerves can be inhibited, and muscular tension is blocked; the arformoterol acts on a beta 2-receptor on an airway smooth muscle cell membrane, so that the release of degranulation and media of mast cells and basophils is reduced, the permeability of capillaries is reduced, and swinging of airway epithelial cilia is increased; the fluticasone is an effective anti-inflammatory drug, and when the three drugs are combined for use, the three mechanisms jointly exert the bronchus relaxing effect and the anti-inflammatory effect; the application range of the triple therapy is wider on the important clinical indexes of reducing acute exacerbation of patients suffering from chronic obstructive pulmonary disease, reducing total-cause mortality rate, improving the lung function of the patients suffering from chronic obstructive pulmonary disease, improving the living quality and the like.

A using method and apparatuses of foramen catheter needle scope of the present invention uses a new approach, new sites and set of apparatuses to block sacral nerves or nerve plexus to reduce pain during operating. The present invention uses an endoscopic video system with foramen catheter needle scope to introduce anesthetic agents via catheter through foramen of sacral bone to block the sympathetic and parasympathetic nerve fibers of lower pelvis, which includes the innervation of uterus, vaginal canal and perineum.

The invention provides a pharmaceutical preparation containing tiotropium bromide and arformoterol. The pharmaceutical preparation comprises tiotropium bromide or hydrate thereof, and the administration range is 2.5-200 [mu] g; the administration range of the arformoterol or the salt thereof is 4-200 [mu] g; the tiotropium bromide acts on a muscarinic receptor on bronchial smooth muscle, can inhibit cholinergic effect of acetylcholine released at the tail end of parasympathetic nerve, blocks muscular tension, and generates bronchiectasis; the arformoterol acts on beta 2-receptors on airway smooth muscle cell membranes, so that airway smooth muscles are relaxed, release of mast cells, basophilic cell degranulation and media is reduced, permeability of capillaries is reduced, and swing of airway epithelium cilia is increased; when the two medicines are combined for use, the bronchial relaxation effect is achieved through different mechanisms, and on the important clinical indexes of reducing acute exacerbation of a patient suffering from chronic obstructive pulmonary disease, reducing the all-cause mortality, improving the lung function of the patient suffering from chronic obstructive pulmonary disease, improving the living quality and the like, the two medicines are combined for use, so that the application range of the pharmaceutical preparation for indications is wider than that of a single medicine.

The invention discloses a method and a device for testing heart rate deceleration capacity. The method and the device calculate RR interval from a recorded electrokardiagram, and draws an RR interval graph taking the frequency of the RR interval as a horizontal coordinate and the RR interval as a vertical coordinate; a central point is selected from the RR interval graph, L points are taken from the front of the central point and the back of the central point respectively to form RR interval sequence with the length of 2L+1; points with the same subscript in all sequences are calculated to obtain an average value, and the average value is taken as a value of a point corresponding to the subscript in average sequence; and the heart rate deceleration capacity is calculated from the obtained average sequence. The method and the device can be used for testing the activity evaluating index of parasympathetic nerve of the heart rate deceleration capacity, and provide a reliable tool for clinically researching an autonomic nervous system.

The invention belongs to the field of bioengineering-electronic medical equipment, in particular relates to a biological negative electricity insomnia recovery therapeutic apparatus equipment system which comprises a host computer, a biological negative electricity conveyer and a biological negative electricity stimulator. A recovery therapeutic method of the biological negative electricity insomnia recovery therapeutic apparatus equipment system comprises the steps of: generating a direct current negative potential same with a potential of a cell membrane of the human body by using the system, placing an insomniac in a biological negative electric field, enabling the in vivo tissue to generate a physical effect through the action of the negative electric field to the insomniac, regulating the cerebral cortex, the autonomic nervous system and the incretion function; and stimulating meridian points related to the autonomic nervous system by using a biological negative electricity stimulator according to the principle of meridian science and science of acupuncture and moxibustion in traditional Chinese medicine to activate weak parasympathetic nerve, restore the function of inhibiting the excitation, improve the sleep and cure the insomnia.