50results about "Subcutaneous electrodes" patented technology

The present application relates to an apparatus (100) for stimulating a peripheral nerve. The apparatus comprises: an implantable electrode assembly (102), which can be implanted in the body of a patient, and is configured to apply a stimulation signal to a nerve. The implantable electrode assembly (102) comprises: a stimulation electrode (102a), which is fixed to a predetermined position of the body of the patient and is adjacent to a nerve therein, and is configured to operably apply a stimulation signal to the nerve; and an electrode circuit (102b), which is coupled to the stimulation electrode (102a), and is configured to receive stimulation energy in the form of an electromagnetic field, convert the stimulation energy into the stimulation signal and provide the stimulation signal to the stimulation electrode (102a), wherein the stimulation energy is from the outside of the implantable electrode assembly (102). The apparatus further comprises: a stimulation energy generator (104), which can be worn outside the body of the patient, so as to provide stimulation energy to the implantable electrode assembly (102) by means of electromagnetic field coupling. The stimulation energy generator (104) comprises: a generator circuit (658), which is used for generating stimulation energy in the form of an electromagnetic field; and a power source (660), which is coupled to the generator circuit (658), and is configured to supply power to the generator circuit (658).

A defibrillation generator for an implantable defibrillation system comprises a housing, a connector block for connecting an electrode lead assembly to be non-transvenously implanted in a patient, and control device for controlling the operation of the defibrillation generator. The connector block has two connectors, to each of which an electrode lead of the electrode lead assembly, said electrode leads having at least one defibrillation electrode pole, is connectable, wherein the control device is configurable to assume a first operating state if an electrode lead is connected to just one of the two connectors, or a second operating state if electrode leads are connected to each of the two connectors.

Alternating electric fields (e.g., tumor treating fields, a.k.a. TTFields) may be applied to a target region in a subject's body via sheets of graphite that are implanted in the subject's body. One or more ports configured for affixation to the subject's body include or connect to one or more mating electrical connectors. Electrical conductors are positioned to route electrical signals between the electrical connector(s) and the sheets of graphite. The alternating electric fields are applied to the target region by applying (via the ports) an alternating voltage between two sheets of graphite that are positioned on opposite sides of the target region.

In some examples, a tool for, e.g., creating a sub-sternal tunnel in a patient or other use, is described. The tool may include a handle and a tunneling shaft coupled to the handle. The tunneling shaft extends from a proximal end to a distal end, and at least a portion of the tunneling shaft extends in a curved orientation between the first end to the distal end. The distal end of the tunneling shaft includes a cutting tool having a sharp edge. The cutting tool is moveable from a recessed position in which the sharp edge of the cutting tool is recessed into the distal end of the tunneling shaft to a deployed position in which the sharp edge of the cutting tool extends beyond the distal end of the tunneling shaft in the deployed position, e.g., to cut pericardium, scar tissue, and / or connective tissue with the sharp edge.

Systems and methods involving implants positioned within implant pockets through minimally invasive entrance incisions, along with related neurostimulatory implants. In some implementations, implants may be folded, rolled, or otherwise compressed to fit within subcutaneous implant pockets, after which they may be decompressed to fit within an implant pocket having one or more dimensions substantially larger than the entrance incision. Such implants may be used for a variety of purposes, including generating electrical energy for various other implants, including neurostimulatory implants located throughout the body.

The present invention provides a method to reduce pain using electrical stimulation of peripheral nerves in or near the spine. This approach involves an electrical stimulation device including at least one electrode adapted for insertion within a human body and at least one pulse generator operatively coupled with the at least one electrode, wherein the pulse generator delivers electrical stimulation activating at least one peripheral nerve in or near the spine, such as the dorsal rami and its distal branches (e.g., the medial branch nerves, cluneal nerves), the ventral rami and its distal branches (e.g., sacral nerves, gluteal nerves), and those accessed via the paravertebral space (e.g., peripheral spinal nerves), to produce pain relief.

We provide implantable medical devices, particularly subcutaneous devices. [Solution] The device, which can be implanted subcutaneously, comprises a housing, a clip attached to the upper surface of the housing, an electrode, and a circuit within the housing that is electrically in communication with the electrode. The clip includes an upper part, the upper part of the clip is configured to be pressed down onto the xiphoid process and / or the sternum in order to fix the device to the xiphoid process and / or the sternum, with the xiphoid process and / or the sternum between the upper part of the clip and the housing.

A medical device is configured to sense electrical signals and determine that a signal-to-noise ratio criterion is satisfied based on stored electrical signal segments in response to sensed electrophysiology events. The medical device is configured to determine, from one of the stored electrical signal segments, an increased-gain signal segment in response to determining that the signal-to-noise ratio criterion is satisfied. The medical device determines a noise metric from the increased-gain signal segment. In response to the noise metric satisfying a noise detection criterion, the stored electrical signal segment associated with the increased-gain signal segment can be classified as a noise segment.

This invention relates to the use of an alternating electric field to increase the permeability of the blood-brain barrier. [Solution] Many drugs and other molecules cannot normally pass through the blood-brain barrier (BBB). However, when an alternating current field of a specific optimal frequency (e.g., 100 kHz) is applied to the brain, the BBB becomes permeable to those molecules. When the alternating current field is stopped, the BBB eventually returns to its original impermeable state. The BBB is then reopened by reapplying the alternating current field at the optimal frequency. Typically, many frequencies of the alternating current field (e.g., 200 kHz) are ineffective or less effective in inducing permeability than the optimal frequency. However, once the BBB has been opened by applying an alternating current field at the optimal frequency, alternating current fields at non-optimal frequencies can maintain the permeability of the previously opened BBB.

Many drugs and other molecules cannot ordinarily traverse the blood brain barrier (BBB). However, when alternating electric fields at certain optimum frequencies (e.g., 100 kHz) are applied to the brain, the BBB becomes permeable to those molecules. When the alternating electric fields are discontinued, the BBB eventually recovers to its original impermeable state. Subsequently, re-application of alternating electric fields at the optimum frequencies will re-open the BBB. Ordinarily, many frequencies (e.g., 200 kHz) of alternating electric fields are either ineffective or less effective at inducing permeability than the optimum frequencies. But once the BBB has been opened by applying alternating electric fields at the optimum frequencies, alternating electric fields at non-optimum frequencies can maintain the permeability of a previously-opened BBB.

A cardiac pacing system that includes an a pulse generator configured to generate appropriate therapeutic electrical pulses for pacing a heart of a patient from the region of an intercostal space at the cardiac notch, where the therapeutic electrical pulses have one or more of amplitudes, pulse widths, frequencies, or electrode polarities specified by therapy protocols for pacing one or more atria or ventricles of the heart of the patient from the region of the intercostal space at the cardiac notch. The system also includes bifurcated lead having a plurality of cores configured to be advanced in different directions and configured to transmit the therapeutic electrical pulses generated by the pulse generator to pace the heart of the patient from the region of an intercostal space at the cardiac notch.

Provided herein are neural interface systems for a patient, the systems comprising an implantable sensor device and an external processing device. The implantable sensor device comprises: an implantable lead assembly for implantation above the skull and below the skin of the patient, and for recording physiologic parameter information of the patient; and an implantable transmitter for receiving the physiologic parameter information from the implantable lead assembly and for transmitting patient data that is based on the physiologic parameter information. The external processing device receives the patient data from the implantable transmitter. Methods of provided a neural interface are also described.

The present invention provides devices, systems, and methods for pain management (e.g., motor pain management, sensory pain management, etc.), vasodilation, and / or arteriovenous fistula maturation. [Solution] The injection lead assembly 100 comprises a housing 140 having a needle receptacle, a housing lumen, a pin receptacle, and a housing conductive trace; a connector having a connector needle, an internal lumen, a metal pin, and a connector conductive trace; and an injection lead body 110 having an injection lumen, an outlet port, an internal wire, and a tip electrode 112. The injection lead assembly forms an electrical path for transmitting electrical signals across the connector conductive trace, the metal pin, the housing conductive trace, the internal wire, and the tip electrode. The injection lead assembly forms a fluid path for transmitting fluid across the internal lumen, the connector needle, the injection lumen, and the outlet port 118.

A system is provided for driving an implantable neurostimulator lead, the lead having an associated plurality of electrodes disposed in at least one array on the lead. The system comprises an implantable pulse generator (IPG), the IPG including an electrode driver, a load system for determining load requirements, an IPG power coupler, and an IPG communication system. The system also includes an external unit, which includes an external variable power generator, an external power coupler, an external communication system, and a controller for varying the power level of the variable power generator.

The present application relates to a cardiac therapy apparatus. The cardiac therapy apparatus comprises: a subcutaneous defibrillation assembly, which comprises a first control component and is configured to sense a global activation event of a heart, generate a far-field sense signal indicative of the global activation event, and deliver a defibrillation wave to a patient when the patient has malignant arrhythmia; and a leadless myocardial stimulation assembly, which comprises a second control component and is configured to sense a local activation event of myocardium at a predetermined stimulation position, generate a local sense signal indicative of the local activation event, and apply to the predetermined stimulation position an electrical stimulation impulse for enhancing the myocardial contractility, wherein the first control component is coupled to the second control component through wireless communication, and the first control component and / or the second control component are / is configured to determine, at least according to the far-field sense signal and the local sense signal, whether to apply the electrical stimulation impulse to the predetermined stimulation position.

The invention relates to a nerve stimulation set (10) comprising a nerve stimulation device (100) with a distal end (100a), wherein the device (100) includes an electrically conductive stimulation element and a channel for supplying a fluid, and an indwelling cannula (200) with an indwelling cannula tube (240) having a distal end (240a) and a proximal end (240b), wherein the device (100) has a first connector part (180) and the indwelling cannula (200) has a second connector part (280) complementary to the first connector part (180), wherein by connecting the first connector part (180) and the second connector part (280) the device (100) can be fixed in an axial position in which the distal end (100a) of the device (100) extends beyond the distal end (240a) the indwelling cannula (200) protrudes,wherein in the connected state of the first connector part (180) and the second connector part (280) the first connector part (180) and the second connector part (280) are connected to each other in such a way that a circumferential first seal (500) is formed.

Implantable cardiac pacing systems and methods for providing substernal pacing are described. In one example, a cardiac pacing system includes a pacemaker implanted in a patient and an implantable medical electrical lead. The implantable medical electrical lead includes an elongated lead body having a proximal end and a distal portion, a connector configured to couple to the pacemaker at the proximal end of the elongated lead body, and one or more electrodes along the distal portion of the elongated lead body, wherein the distal portion of the elongated lead body of the lead is implanted substantially within an anterior mediastinum of the patient and the pacemaker is configured to deliver pacing pulses to a heart of the patient.

A medical device system is provided for guiding implantation of a medical electrical lead. The system includes processing circuitry configured to receive first patient body image data and second patient body image data and register the first patient body image data and the second patient body image data. The processing circuitry may be further configured to receive a signal from at least one location sensor disposed at a known distance from a feature of a removable outer sheath of a delivery tool configured to deliver an extravascular lead to an implant site of a patient via a non-transvenous pathway. The processing circuitry may determine from the location sensor signal a location of a feature of the removable outer sheath in a coordinate system space corresponding to the second patient body image data.

The invention provides an implantable nerve stimulation electrode and a preparation method thereof, and relates to the technical field of implantable medical instruments, and the implantable nerve stimulation electrode is constructed to be used for transmitting stimulation signals to columnar nerves located at the lower jaw and / or neck position of a human body. The electrode comprises a stimulation end, an extension section and a connection end. The connecting end is arranged at the near end of the electrode and used for receiving a stimulation signal; the extension section is connected between the stimulation end and the connection end, the extension section comprises a protection sleeve and a wire, the wire is configured to be used for transmitting stimulation signals, the wire is arranged in the protection sleeve in a penetrating mode and is of a spiral structure, and the spiral structure has elasticity and can extend in the length direction of the protection sleeve when being pulled; after the tension is eliminated, the protective sleeve retracts along the length direction of the protective sleeve; the range of the ratio of the outer diameter of the spiral structure to the diameter of the wire is set to be 3-10. The stimulation end is arranged at the far end of the electrode, fixed to the columnar nerve and used for outputting stimulation signals to the columnar nerve. The defect that the ductility of the electrode is insufficient in the prior art is overcome.

An implantable cardioverter-defibrillator including: a housing, wherein the housing includes a stimulation unit and a sensing unit; a combined defibrillation and sensing electrode for delivering stimulation pulses to a patient in need thereof and for sensing electrocardiogram signals of the same patient, wherein the combined defibrillation and sensing electrode is electrically connected to the stimulation unit and to the sensing unit. The combined defibrillation and sensing electrode includes an electrode pole that serves for delivering stimulation pulses to a patient in need thereof and for sensing electrocardiogram signals of the same patient. In addition, the sensing unit includes a circuitry enabling the sensing unit to tolerate a post-potential of a stimulation pulse delivered by the combined defibrillation and sensing electrode.

This disclosure relates to curved medical electrical leads. For example, the medical electrical lead includes a lead body and a high-voltage electrode located on the lead body, the high-voltage electrode including a proximal coated portion, a distal coated portion, and an uncoated portion. Furthermore, the medical electrical lead includes a first low-voltage electrode and a second low-voltage electrode distal to the first low-voltage electrode, wherein a first wire passes through the first and second low-voltage electrodes, wherein a second wire passes through the first low-voltage electrode and the uncoated portion, the second wire forming a first angle with the first wire, and wherein a third wire passes through the second low-voltage electrode and the uncoated portion, the third wire forming a second angle with the first wire.

The subcutaneously implantable device includes a clip configured to secure the subcutaneously implantable device to muscle, bone, and / or a first tissue, a clip secured adjacent to the clip, and a first prong having a proximal end and a distal end extending away from the clip and configured to contact an organ, nerve, and / or a second tissue. A first electrode on the first prong is configured to contact the organ, nerve, and / or second tissue. A cable is conductively coupled to the first electrode, the cable configured to be connected to a remote device for electrically coupling the subcutaneously implanted device to the remote device. The remote device is a pacemaker device or a defibrillator device disposed within the patient's body.

The present disclosure relates to synchronization of anti-tachyarrhythmia pacing in an extravascular implantable system. An extravascular implantable cardioverter defibrillator (ICD) system receives cardiac electrical signals through an extravascular sensing electrode vector by an electrical sensing circuit and senses cardiac events from the cardiac electrical signals. The ICD system detects a tachyarrhythmia from the cardiac electrical signals and determines a tachyarrhythmia cycle length from the cardiac electrical signals. The ICD system determines an ATP interval based on the tachyarrhythmia cycle length and sets an extended ATP interval that is longer than the ATP interval. The ICD delivers ATP pulses to the patient's heart via an extravascular pacing electrode vector that is different from the sensing electrode vector. The ATP pulses include a lead ATP pulse delivered at the extended ATP interval after a cardiac event is sensed from the cardiac electrical signals and a second ATP pulse delivered at the ATP interval after the lead ATP pulse.

An implantable medical device includes a housing, a lead connector connected to the housing that is configured to connect a lead to the housing, and circuitry in the housing that is configured to provide monitoring, therapeutic, and / or diagnostic capabilities with respect to an organ, a nerve, and / or a first tissue. The circuitry includes sensing circuitry and / or therapy circuitry, a first power source, and a transceiver. The implantable medical device further includes an antenna attachment including a head configured to be subcutaneously positioned in a patient and an arm extending between the housing and the head, wherein the head is in electrical communication with the first power source and the transceiver, and wherein the antenna attachment is flexible.

A stimulation system includes: a mouthpiece including one or more sensors to intraorally sense physiological data of a subject; and a subcutaneously implantable device to be in communication with the mouthpiece and including one or more stimulators to stimulate at least one of a nerve or a muscle of the subject to treat apnea.

An endovascular device includes an elongated body, an expandable structure, and an electrode array. The elongated body is configured to be introduced into a blood vessel of a patient. The electrode array includes a flexible polymer packaging and one or more electrodes electrically coupled to the elongated body. The flexible polymer packaging is coupled to expandable structure and the one or more electrodes. In some examples, the expandable structure is a non-tubular expandable structure configured to bend around a longitudinal axis. In some examples, the expandable structure is a tubular expandable structure, and the one or more electrodes are embedded in the flexible polymer packaging. In some examples, the expandable structure is mechanically coupled to the elongated body and configured to be positioned within a stent.

A system for stimulating a tissue target in a body with an injectable electrode, either fully or partially implanted, may employ a protection device to prevent over-voltage or over-current from an external pulse generator (EPG) to the injectable electrode. Current is supplied from the EPG transcutaneously to the fully implanted injectable electrode and percutaneously to the partially implanted injectable electrode by various electrical connectors.

A subcutaneously implantable device includes a housing, a clip attached to the housing that is configured to anchor the device to a muscle, a bone, and / or a first tissue, and circuitry in the housing that is configured to provide monitoring, therapeutic, and / or diagnostic capabilities with respect to an organ, a nerve, the first tissue, and / or a second tissue. The circuitry includes a first power source, and a transceiver. At least one antenna on the device is in electrical communication with the first power source and the transceiver. The at least one antenna is configured to be subcutaneously positioned in a patient.

Systems, devices and methods are disclosed related to shapeable lead assemblies. Such lead assemblies can be configured to be shaped in a desired manner before and / or during a procedure, such as, for example, after the lead assembly has been at least partially placed within the anatomy of a subject. The shapeable lead assembly can be shaped during a neuroregenerative procedure to contact and / or otherwise interface with a targeted nerve.

An injectable wire structure electrode can assimilate with surrounding tissues after injection, inducing in-growth of blood vessels, collagen and other tissue. Assimilation secures the electrode to the tissue without sutures and prevents relative motion which can lead to inflammation and scarring. Associated methods of manufacturing and injection are disclosed, as well as systems including a dermal multiplexer for power delivery.