40results about "Skin piercing electrodes" patented technology

Measurements are performed on biological subjects by using microstructures to penetrate the functional barriers of the target. [Solution] A system for performing measurements on a biological object, comprising: at least one substrate 511 including a plurality of plate microstructures 512.1, 512.2 configured to penetrate the stratum corneum of the object; at least one sensor operably connected to at least one microstructure and configured to measure a response signal from at least one microstructure; and one or more electronic processing devices configured to perform at least one of the following: determine the measured response signal, provide an output based on the measured response signal, perform an analysis using at least part of the measured response signal, and store data indicating at least part of the measured response signal.

Providing an electrode array for electroporation, as well as related systems and methods. [Solution] An electrode array for use with an electroporation device includes a support member having an upper surface and a bottom surface, defining a plurality of injection channels extending from the upper surface to the bottom surface. The plurality of needle electrodes are coupled to the support member such that the distal ends of the plurality of needle electrodes extend to a needle depth below the bottom surface. The plurality of needle electrodes are arranged in a matrix pattern having rows and columns of needle electrodes arranged along the support member. The plurality of injection channels are dispersed within the matrix pattern.

This skin aesthetic device allows for precise adjustment of the degree to which multiple needles are inserted, ensuring sufficient skin aesthetic effects, and enables easy correction of errors in needle insertion during use. [Solution] The skin beauty device 100 has a transfer mechanism that screws onto the ball screw rotating shaft of a stepping motor (SM) and moves forward from the origin position, then moves backward to return to the origin position. The transfer mechanism moves forward by a distance corresponding to the forward signal of the SM, pushing the needle bundle, so that multiple needles fixed to the needle bundle are precisely inserted into the skin to an extent corresponding to the forward signal, and alternating current supplied via the transfer mechanism is passed through the multiple needles for a predetermined time inside the skin to promote skin regeneration by forming tiny wounds. When it senses that the transfer mechanism has moved backward by a distance corresponding to the backward signal of the SM and returned to the origin position, the transfer mechanism is moved forward again by a distance corresponding to the origin correction drive signal of the SM to correct the origin position.

According to the present disclosure, it is possible to precisely adjust a degree of insertion of the plurality of needles fixed to the needle bundle in consideration of skin thickness (for example, a thickness from epidermis to dermis of the skin) to an extent that a sufficient skin beautification effect is expected, and when an error occurs in the degree of insertion of the needles due to forward or rearward movement of the conveyor during use, the error in the degree of insertion of the needles can be easily corrected by correcting the starting point position of the conveyor using a starting point position detector.

The hybrid stimulation system is an electrical stimulation system serves to delivered an electrical stimulation impulse to the heart (human or animal heart) , using a combination of internal (intravascular) and external (body surface) electrodes, the hybrid electrical stimulation system can be used for pacing of the heart during slow heart beat (bradycardia), or shocking the heart during fast heart beat (Tachycardia) , or to terminate fast abnormal heart beat (tachy-arrhythmia) by means of override pacing (Anti-tachycardia pacing). This hybrid system can be used and introduced into the body without the need for imaging guidance such as fluoroscopy or echocardiography to insert the internal component, and does not require direct contact between the internal pacing wire and the myocardium (internal heart surface).

Systems and methods are provided for applying electrical stimulation to a body by an electrode spaced from a target nerve of passage. It has been discovered that pain felt, or perceived to be felt, in a given region of the body can be treated by stimulating muscle close to a “nerve of passage” in a region that is superior (i.e., cranial or upstream toward the spinal column) to the region where pain is felt, such as in a case of post-amputation residual limb pain, or purportedly felt in the case of post-amputation phantom limb pain.

This subject discloses a method and apparatus for treating gastrointestinal disorders, the method comprising implanting a pulse generator and a plurality of electrodes subcutaneously in the abdomen of a patient, wherein the electrodes are in electrical contact with a target region in the abdomen of the patient, and activating the target region by applying electrical stimulation.

An electrochemical sensor device for introducing a needle electrode into the skin of a subject to contact a target body fluid or tissue and detect a target analyte. The device has a movable part for biasing the needle electrode against the skin of the subject and a power management function for supplying operating power to the sensor electronics before and after the device is disposed.

The invention relates to an acupuncture needle (1) comprising a needle body (2), wherein the needle body (2) has a penetrating region (3), wherein, during use of the acupuncture needle (1), the penetrating region (3) penetrates into the body and comes into direct contact with the subcutaneous tissue (4). The aim of the invention is to provide an acupuncture needle having enhanced therapeutic properties. This aim is achieved in that the acupuncture needle (1) comprises at least one first material (5) and at least one second material (7), wherein the first material (5) and the second material (7) are arranged, at least in certain regions, in the penetrating region (3) such that the first material (5) and the second material (7) come into direct contact with the subcutaneous tissue during use, and wherein the first material (5) and the second material (7), during use, form a galvanic element together with the subcutaneous tissue.

The present invention relates to a needle device (105) configured for placement or placement on the auricle and / or earlobe, wherein the needle device (105) has a handle device (400) and / or a placement unit (400) for placing the needle device (105) on the auricle and / or earlobe.

The disclosed system and method provides a mobile defibrillator system which may include a mobile defibrillator (AED) unit configured to be operablely connected to a device capable of running an application. The mobile AED unit may include a circuit for delivering an electric shock to a person and one or more pads. Each pad may include one or more needles electrically connected to the circuit and may be configured to puncture the person's skin, be present in the person's body, and deliver an electric current from the electric shock to the person.

Disclosed are a treatment tip, a hand tool and a needle treatment device. A treatment tip includes a needle plate portion, an adapter board portion and a first flexible circuit board. The needle plate portion is provided with a plurality of needles. The needle plate portion is slidably connected to the adapter board portion. The driving end of the handpiece drives the needle plate portion to move in the first direction relative to the adapter board portion. The first flexible circuit board is connected to the needle plate portion and the adapter board portion respectively. The radio frequency energy output by the handpiece passes through the adapter board portion, the first flexible circuit board and the needle plate portion, and the plurality of needles are controlled to generate heat in different zones. The present application is intended to increase the service life of the treatment tip, reduce the size of the treatment tip, and improve the stability and safety of the use of the treatment tip.

Methods and apparatus for the reproducible, consistent and efficacious delivery of a therapeutic agent to a subject. The present disclosure comprises apparatus for the controlled administration of the therapeutic agent through an orifice to the subject, a plurality of penetrating electrodes arranged with a predetermined spatial relationship relative to the orifice, and an electrical signal generator operatively connected to the electrodes.

A microblade for electrostimulation for use in a skin treatment procedure, includes a tip portion formed to be gradually reduced in outer diameter toward a tip and a body portion extending outward from the rear end of the tip portion and having a constant outer diameter. The tip portion includes a first tip edge portion formed by a pair of first tip inclined surfaces, a second tip edge portion formed by a pair of second tip inclined surfaces, and a pair of tip connection surfaces, each interconnecting two adjacent first and second tip inclined surfaces. The body portion includes a first body edge portion formed by a pair of first body inclined surfaces, a second body edge portion formed by a pair of second body inclined surfaces, and a pair of body connection surfaces, each interconnecting two adjacent first and second body inclined surfaces.

Example apparatuses and systems are disclosed for providing controlled delivery of electrolysis treatment and cellular permeabilization treatment to a site in tissue. A system disclosed may include an electrode, a power supply, and a controller. The controller may control a charge applied to the electrode to induce a direct current through the aqueous matrix to produce electrolysis products and a voltage to produce electroporation. The duration and magnitude of the charge applied may determine the dose of the products and the degree of the permeabilization of cells in the treatment site. The composition of the electrodes may be chosen in accordance with the desired products produced and electro -poration effects. An apparatus is disclosed that may be in the form of electrodes for electrolysis and electrodes for electroporation applied to the tissue. An apparatus is disclosed that may be used for treating internal tissue.

This invention discloses a treatment head and handle for scalp care. The treatment head of this invention includes: a cover portion having a front end face with a plurality of needle insertion and exit holes; a cooling plate portion mounted on the cover portion; and a pair of channel portions located on both sides of the cover portion for receiving the two ends of the cooling plate portion. The treatment head of this invention has the following advantages: it provides the function of effectively cooling the skin at the treatment site during high-frequency invasive treatment, and its compact design enables convenient storage, distribution, management, and assembly of consumables.

In an illustrative embodiment, methods and system for increasing coagulation potential and / or triggering a higher platelet activation rate in a subject via auricular neurostimulation include contacting skin of the subject with one or more therapeutic electrodes, each electrode positioned in a respective region of nerve structures of the auriculotemporal nerve (ATN), nerve structures connected to the ATN, nerve structures of the auricular branch of the vagus nerve (ABVN), or nerve structures connected to the ABVN, applying, to the electrodes, one or more stimulation patterns.

To provide a treatment tip and handpiece for scalp care that include this tip, while also featuring a cooling function that cools the skin of the treatment area during high-frequency immersion treatment, tightening skin tissue, alleviating pain, and providing a soothing effect on the skin, all while being compact in design for easy storage, distribution, management, and assembly. [Solution] The treatment tip of the present invention includes a cap portion having a tip surface formed with multiple needle entry and exit holes, a cooling plate portion attached to the cap portion, and a pair of terminal portions located on both sides of the cap portion and accommodating both ends of the cooling plate portion, and is characterized by its ability to effectively cool the skin of the treatment area during high-frequency immersion treatment, and its compact design makes it easy to store, distribute, manage, and assemble as a consumable item.

The present disclosure relates to, in part, devices that allow for the delivery of an antibody or a therapeutic protein, or a fragment thereof, in vivo, and the devices are useful for treatment of cancer, inflammatory diseases, and infectious diseases.

Disclosed herein are patches, methods, devices, and systems for delivering a non-aggregating peptide, such as alcadein and its fragments, into a subject. In some aspects, the patch includes a backing, a matrix comprising a non-aggregating peptides disposed within the matrix, and a release liner. In other aspects, the method includes opening at least one channel in the subject's skin, applying the patch described herein, thereby treating a disease or disorder associated with the brain, such as Alzheimer's disease.

Described herein are methods and systems for using the treatment tip apparatuses and high-voltage connectors with robotic surgical systems. For example, retractable treatment tip apparatuses (e.g., devices, systems, etc.) including one, or more preferably a plurality, of electrodes that are protected by a housing (which may be retractable) until pressed against the tissue for deployment of the electrodes and delivery of a therapeutic treatment, are disclosed. In particular, these apparatuses may include a plurality of treatment needle electrodes and may be configured for the delivery of nanosecond pulsed electric fields. Also described herein are high-voltage connectors configured to provide high-voltage energy, such as nsPEF pulses, from a generator to the retractable treatment tip apparatuses.

Disclosed are a treatment tip for a scalp care handpiece and a handpiece including the same. The treatment tip includes a cap part having a tip surface formed with a plurality of needle entry / exit holes, a cooling plate part mounted on the cap part, and a pair of terminal parts located on both sides of the cap part and accommodating both ends of the cooling plate part. The treatment tip provides a function capable of effectively cooling the skin of a treatment site during a radio-frequency invasive treatment, and facilitates storage, distribution, management, and assembly as a consumable by compact design.

According to the present invention, the insertion depth of multiple needles fixed in the needle cluster can be precisely adjusted to a level that can fully expect cosmetic skin effects, taking into account skin thickness (e.g., the thickness from the epidermis to the dermis). Furthermore, when errors in the needle insertion depth occur during use as the mover moves forward or backward, the origin position of the mover can be corrected using an origin position sensor, thereby easily correcting the error in the needle insertion depth.