61results about How to "Reduce pain levels" patented technology

A compact lancing includes a housing, a moveable lancet holder disposed within the housing and configured to hold a lancet, a launching mechanism disposed within the housing, and arming and trigger mechanisms disposed at least partially within the housing. In addition, the launching mechanism includes a launch spring and a retraction spring. The lancet holder, launching mechanism, arming mechanism and trigger mechanism are operatively connected to lance a target site with a lancet held by the moveable lancet holder. In addition, the retraction spring is configured in an essentially concentric arrangement with the launch spring, thereby providing for compactness in design.

Described and illustrated herein is an exemplary lancing device. The exemplary lancing device comprises: a first housing having spaced apart proximal and distal ends disposed along a longitudinal axis; a chassis disposed in the first housing in a fixed relationship with the first housing; a movable member disposed in the chassis and configured for movement along the longitudinal axis and in the first housing; a lancet coupled to the movable member; and a lancet depth adjustment member retained by both the first and chassis so that the lancet depth adjustment member is rotatable relative to both housings to provide for a plurality of stop surfaces to the movable member. Other embodiments and methods are also described.

Described is a device and method for administration of molecules to tissue in vivo for various medical applications, the device comprising a single-needle electrode which provides for the ability, when the needle is inserted into tissue, such as skin or muscle, to pulse tissue with a non-uniform electric field sufficient to cause reversible poration of cells lying along or in close proximity to the track made by the needle upon its insertion into said tissue

Described herein are methods for neuromodulating brain activity of one or more target brain regions, the methods using Transcranial Magnetic Stimulation (TMS) to produce robust analgesia. In particular, described herein are systems for arranging one or more (e.g., a plurality) of TMS electromagnets in a configuration and applying sufficient energy to neuromodulate the dorsal anterior cingulate gyrus relative to cortical brain regions to significant modulate pain, including the pain of fibromyalgia.

An electrode arrangement, in particular for the intracardial discharge of defibrillation pulses in the atrium of a heart, comprising an electrode line which in the region of its distal end has a plurality of electrically conductive surface portions as electrodes which can be electrically connected by way of the electrode line to an electrical pulsedischarging device such as defibrillator, wherein the electrode line is adapted to be split in the electrode-bearing region of its distal end into at least two respectively electrode-bearing branches.

An electrical current pulse generator causes a magnetic coil attached to a human patient to create magnetic pulses within that patient's body. By Faraday's Law, the magnetic pulses cause electrical current pulses within the patient that provide pain relief with essentially zero adverse side effects. The electrical current pulse generator has dials that allow the operator to adjust several significant parameters including magnetic pulse strength, the time between pulses and the total number of pulses for a pain treatment.

Described herein are methods for neuromodulating brain activity of one or more target brain regions, the methods using Transcranial Magnetic Stimulation (TMS) to produce robust analgesia. In particular, described herein are systems for arranging one or more (e.g., a plurality) of TMS electromagnets in a configuration and applying sufficient energy to neuromodulate the dorsal anterior cingulate gyrus relative to cortical brain regions to significant modulate pain, including the pain of fibromyalgia.

A physiological parameter system has one or more parameter inputs responsive to one or more physiological sensors. The physiological parameter system may also have quality indicators relating to confidence in the parameter inputs. A processor is adapted to combine the parameter inputs, quality indicators and predetermined limits for the parameters inputs and quality indicators so as to generate alarm outputs or control outputs or both.

The invention provides modified antibodies directed against GD2 that have diminished complement fixation relative to antibody-dependent, cell-mediated cytotoxicity, which is maintained. The modified antibodies of the invention may be used in the treatment of tumors such as neuroblastoma, glioblastoma, melanoma, small-cell lung carcinoma, B-cell lymphoma, renal carcinoma, retinoblastoma, and other cancers of neuroectodermal origin.

Described is a device and method for administration of molecules to tissue in vivo for various medical applications, the device comprising a single-needle electrode which provides for the ability, when the needle is inserted into tissue, such as skin or muscle, to pulse tissue with a non-uniform electric field sufficient to cause reversible poration of cells lying along or in close proximity to the track made by the needle upon its insertion into said tissue

The invention provides an external medicine for treating tinea manuum and athlete's foot, which is a liniment prepared by immersing solomonseal, kuhseng, broom cypress fruit, cnidium fruit, stemona root, yellow-corktree bark, cotex dictamni, ageratum and dandelion in mature vinegar for 7 to 15 days, sterilizing and sealed-packaging the filtrate. The medicine clears away heat and toxic material, removes dampness to relieve itching, dries damp, expels the wind, destroys parasites, and has strong epiphyte killing function and infiltration function. The medicine can effectively eliminate pathogenic dermatophyte, has good curative effect on tinea manuum and athlete's foot, and has little irritation, low pain degree, light side effect and good curative effect; tinea manuum and athlete's foot have little possibility of relapsing. 100 cases of clinical experiments show that the effective rate of the medicine is 90%.

This invention relates to a topical gel drug product preparation containing a composition comprising an isolated polypeptide having a carboxy-terminal amino acid sequence of an alpha connexin (ACT peptide), peptide stabilizers, excipients, buffering agents, and the like. A formulation and preparation steps are disclosed for the manufacturing of a stable, elegant, and pourable topical gel. The resulting formulation possesses long term stability suitable for aesthetic as well as therapeutic applications including the prevention of scaring and accelerated healing of wounds. Methods for treatment of chronic wounds, including chronic ulcers, are also provided.

The invention discloses a sugar-free heart-supplementing dragonhead granule, which is produced by following raw material of weight proportion: dragonhead extraction 1 to 10, starch1 to 10, calcium carbonate 1 to 10, dextrine 1 to 10, xylo-oligosaccharide 0.5 to 3, xylose 1 to 10, polyvinyl pyrrolidone solution and fruit flavor; preparation technology is as below: dragonhead extraction, starch, calcium carbonate, dextrine, xylose and fruit flavor are measured according to proportion, mixed evenly and crushed and sifted out through 80 mesh sieve, moistened using 0.01% to 0.05% of PVP ethanol solution before non-slurry pelletized at granulation machine and then dried, thereby producing the granule in pharmacy. The sugar-free heart-supplementing dragonhead granule has the advantages of having good taste, improving increment environment of bifidobacteria for intestines and stomach, improving digestion and absorption function for intestines and stomach and being suitable for adjuvant therapy of diabetic patients with cardio-cerebrovascular disease caused by diabetes.

The invention belongs to the field of molecular biology and particularly relates to a kit for early screening of liver cancer and a using method of the kit. The invention firstly discovers that SCAND3can serve as a methylation marker for detecting the liver cancer. Sequences of primers for detecting SCAND3 methylation are as follows: the sequence of a forward primer is shown as SEQ ID NO. 1; thesequence of a reverse primer is shown as SEQ ID NO. 2; the sequence of a fluorescence probe is SEQ ID NO. 3; the 5' terminal of the probe is labeled with FAM, and the 3' terminal of the probe is labeled with MGB. The SCAND3 is the methylation marker for early screening of the liver cancer, is used for liver cancer diagnosis, and has the advantages of high sensitivity and strong specificity, and particularly in a patient having the AFP (Alpha-Fetoprotein) of less than 400 ug / L, the SCAND3 methylation incidence reaches 60%. Therefore, the kit disclosed by the invention takes the SCAND3 as the methylation marker, is applicable to diagnosis of the liver cancer, and is particularly applicable to diagnosis of early liver cancer.

The invention discloses a vertical obstetric table, belonging to a gynecology medical appliance. The vertical obstetric table comprises a table rest, a mattress and table legs, wherein the back of the table rest is provided with supporting posts; the table rest is backwardly inclined, has a radian and is fixedly connected with the mattress; one edge of the mattress is in an arc shape; the outer edge of the mattress is connected with auxiliary rods which are in the same plane with the mattress; the two auxiliary rods outwardly and obliquely stretch; and the mattress and the auxiliary rods are connected with the table legs. The invention is scientifically designed, meets human physiology, effectively protects safety of a mother and a son, lightening labor intensity of medical workers and is applied for being promoted and used in vast gynecology medical institutions.

The invention discloses a treatment and rehabilitation instrument for cervical spondylosis. The treatment and rehabilitation instrument comprises a base, a sliding plate and a traction mechanism, wherein the middle of the base is bulged upwards to form an indent cavity body; the sliding plate is arranged on the indent cavity body; an inclined plate which inclines downwards is arranged at the outer lateral end of the sliding plate; and the traction mechanism is connected with the sliding plate. In the treatment and rehabilitation instrument, the sliding plate supports heads and necks to drag forwards in the state of keeping cervical vertebra physiological curvature by utilizing the self weight of the heads and the necks of users through the traction mechanism and stretches naturally according to the cervical vertebra physiological curvature to promote the recovery of the cervical vertebra physiological curvature and relieve and remove symptoms at lesion sites gradually, so that the symptoms are treated and relieved. The treatment and rehabilitation instrument has the advantages of simplicity in operation, easiness to understand and accept by patients and the like, is controlled automatically by utilizing the self weight of the heads and the necks and is safe and effective.

A method of reducing the level of pain experienced by a patient during a pain-inducing dermatological treatment by using non-pharmacologic means is described. The method employs the use of multiple bursts of a gas to stimulate a touch sensation in or near the tissue to be treated using the dermatological treatment in order to reduce and / or relieve pain. The method can be used alone or can be used in combination with other non-pharmacologic and / or pharmacologic methods of relieving pain in order to make a patient more comfortable during or following the dermatological treatment.

The invention belongs to the technical field of medical caring articles, and particularly relates to a multifunctional turnover device. The multifunctional turnover device solves the technical problem that practicability is poor in the prior art and comprises an inflatable air sac cushion made of flexible materials. The inflatable air sac cushion is connected with an inflating / deflating mechanism. The inflatable air sac cushion is provided with a middle cushion which is arranged in the middle and extends in the axial direction. A left wedge-shaped cushion and a right wedge-shaped cushion are arranged on the two sides of the middle cushion respectively. The middle cushion, the left wedge-shaped cushion and the right wedge-shaped cushion are respectively connected with the inflating / deflating mechanism. The middle cushion is provided with a horizontal middle plane when being in the inflated state, the left wedge-shaped cushion is provided with a left slope of which the height decreases gradually from the left side of the left wedge-shaped cushion to the middle cushion when the left wedge-shaped cushion is in the inflated state, and the right wedge-shaped cushion is provided with a right slope of which the height decreases gradually from the right side of the right wedge-shaped cushion to the middle cushion when the right wedge-shaped cushion is in the inflated state. The multifunctional turnover device has the advantages that practicability is high, pressure can be reduced effectively, and pressure sores can be effectively prevented.

The invention discloses a traditional Chinese preparation for treating ulcers, and the traditional Chinese preparation is prepared by the following medicinal materials by weight ratio: 10-30g of Chinese gall, 8-20g of Chinese violet, 10-18g of Mongolian dandelion herb, 10-20g of figwort root, 8-15g of golden thread, 10-30g of baical skullcap root, 10-25g of vietnamese sophora root, 20-30g of natural indigo and 6-12g of borneol. The medicament is mainly used for treating oral ulcers, peptic ulcers, ulcerative colitis and other mucosal ulcer diseases, and can rapidly stop pain and astringe the ulcer surfaces, the treatment course is short, the individual differences are avoided and the treatment effects are significant. The medicament is simple in ingredients, belongs to pure traditional Chinese medicine preparations and has no toxic or side effects. The medicament powder can be effectively adsorbed on the ulcer surfaces for directly acting on focuses, the medicament effect is sustained, the adsorption of the medicament on the ulcer surfaces has not been reported in the aspect of traditional Chinese medicine theory, and the formula still belongs to the first time.

A bloodless glucose measuring and monitoring device which comprises a main computer and a PCB with a LCD display; a microprocessor; a blood glucose detection circuit connected to the microprocessor which includes a blood glucose detection module; and a memory module, a power module and a timekeeping module connected to the microprocessor. The PCB comprises a body resistance acquisition circuit with a body resistance acquisition module electrically connected to the microprocessor for measuring a body resistance between two points of skin of a human body and communicates with the microprocessor such that the body resistance obtained by the body resistance acquisition module is translated into a blood glucose value through the microprocessor and then the blood glucose value is displayed through the LCD display of the main computer.

The invention comprises componentry and devices for light therapy application to a patient in need thereof. The present invention relates to controllers for light therapy devices, light delivery elements, light guides, light guide arrangements configured to deliver personalized light therapy to one or more patients, with related componentry, dosage, and configurations of light therapy delivery elements (e.g., bandages, garments, braces, inserts etc.) suitable to deliver light therapy to one or more patient body areas and associated tissues, as well as sensors for monitoring treatment progressand dosage optimization. Methods of delivering light therapy to a patient and treatment of associated medical indications are also set out herein. Personalized LLLT dosage configurations and telemedicine LLLT treatment platforms and systems are also provided herein.

The invention discloses a Chinese medicinal composition for treating trigeminal neuralgia. According to pathogeny of trigeminal neuralgia, the Chinese medicinal composition is prepared from Chinese medicinal herbs of dahurian angelica root, szechuan lovage rhizome, raw liquorice root, aconite main root and Chinese angelica which have the effects of activating blood, promoting Qi, expelling wind and cold, freeing orifices and easing pain through scientific compatibility; more than ten years of clinical trails prove that after a patient takes the Chinese medicinal composition, the symptom of trigeminal neuralgia rapidly disappears; normal physiological function of trigeminal neuralgia is restored; and therefore, the Chinese medicinal composition achieves the aim of addressing both the symptoms and root causes, has high cure rate, and prevents relapse.

The invention discloses oral traditional Chinese medicine composition for treating migraine, belonging to the field of the traditional Chinese medicine. The oral traditional Chinese medicine composition for treating migraine comprises the following raw Chinese herbal medicine by weight: 10 grams of saposhnikovia divaricata, 10 grams of white atractylodes rhizome, 12 grams of chrysanthemum, 12 grams of Chinese angelica, 10 grams of notopterygium, 10 grams of poria, 10 grams of radix rehmanniae, 10 grams of ligusticum wallichii, 10 grams of rhizoma anemarrhenae, 6 grams of asarum, 10 grams of red paeonia, 15 grams of codonopsis pilosula, 10 grams of cassia seeds, 20 grams of uncaria and 20 grams of pinellia. The oral traditional Chinese medicine composition has the definite efficacy of calming liver wind, reducing the phlegm and activating the collaterals and can take effect quickly to treat both the primary aspect and the secondary aspect of the migraine.

The invention discloses frankincense-myrrh compound volatile oil and its preparation method and use. The preparation method of the frankincense-myrrh compound volatile oil comprises that crude frankincense and crude myrrh are mixed according to a weight ratio of (1: 50) to (50: 1) and the frankincense-myrrh compound volatile oil is extracted from the mixture. The frankincense-myrrh compound volatile oil can be extracted by a steam distillation technology, an organic solvent immersion extraction technology or a supercritical extraction technology. A result of an experiment shows that the frankincense-myrrh compound volatile oil has good effects of resisting isoprenaline-caused rat myocardial ischemia, protecting cardiocytes cultured in vitro from anoxia / reoxygenation, relieving angina and reducing angina attack frequency or reducing a pain degree in an angina attack, has treatment effects which are obviously better than treatment effects of crude frankincense-myrrh powder and a frankincense-myrrh water decoction, can be utilized for preparation of medicinal preparations for treating myocardial ischemia and / or angina, and especially can be utilized for preparation of a medicinal preparation for treating heart blood stasis-caused angina.

The invention discloses a patella inferior pole fracture internal fixing device and a screw fixing method, the patella inferior pole fracture internal fixing device comprises an arc-shaped fixing plate, the arc-shaped fixing plate is attached to a patella; effectively wraps and fixes the subpatellar comminuted fracture block and limits the displacement of the subpatellar comminuted fracture block,and meanwhile, tightly contacts the patella body with the subpatellar comminuted fracture block and pressurizes and fixes the patellar body; the locking between the screw and the steel plate can effectively improve the pull-out resistance of the screw, so that the stability of the fracture block and the internal fixation device is further enhanced, and the looseness and failure of internal fixation are reduced; besides, suture tension reduction protection can be achieved, suture tension reduction stress and patellar ligament traction fracture block stress are kept in dynamic balance, fractureblock displacement or internal fixation failure during early knee bending movement is effectively avoided, meanwhile, damage interference to patellar tendons can be relieved, the tension band principle is considered, the mechanical principle is better met. And a more effective internal fixation choice is provided for treating patella inferior pole fracture, especially comminuted patella inferiorpole fracture.

A surgically invasive pointed article for skin penetration and its fabrication method are presented. The present invention comprises a protruding sharp end portion and a body portion, the protruding sharp end portion comprising at least one penetration tip that can be disabled after use. The tip disablement after use is an effective safety measure in eradicating accidental injuries and re-use. The tip disablement can be carried out manually by the user or automatically if the article is used with a custom-made tip-disabling applicator. The skin penetration device can be used as a lancet for blood sampling, a needle for immunization and skin allergy testing, or a skin breaching device for transdermal drug delivery. The second aspect of the invention is a method for preparing the surgically invasive pointed article for skin penetration. The preparation method includes injection mould the articles into at least two body segments, the first body segment comprising at least one protruding end for skin penetration, and the second body segment being hollow forming a handle for handling purpose or an adaptor for fitting into an applicator. The third aspect of the invention is an over-moulding process for packaging purposes, wherein the articles moulded with a first material mentioned above are over-moulded with a second softer and cheaper material to form various additional functional parts.