Kidney stone removal system is disclosed having components including a
handle mechanism, a
nozzle tip, and a guiding device. The
handle mechanism employs a trigger that enables control of
irrigation and vacuum / suction. Depression of a trigger in the trigger mechanism conveys status of vacuum / suction and
irrigation to a user by providing increased resistance at different points of depression. When the trigger is in a home (undepressed) position,
irrigation and vacuum / suction are turned off. When the trigger is in a fully depressed position, irrigation and vacuum / suction are turned on. When the trigger is in an intermediate position, irrigation may be turned on, while vacuum / suction remains turned off. The
nozzle includes one or more irrigation ports positioned at a distal end of the
nozzle and having an irrigation port departure angle of 30 to 60 degrees for directing irrigation fluid forward and laterally from the distal end of the nozzle. The guiding device is configured to be removably positioned in the nozzle for receiving a debris fragmentizing device, such as a
laser device. The guiding device is configured to prevent an
unintended movement of the fragmentizing device when the fragmentizing device is positioned in the nozzle while allowing fluid and debris to flow past the fragmentizing device and through a
vacuum tube.