50 results about "Radiofrequency ablation" patented technology

The invention discloses a vein radiofrequency ablation system based on parallel thermocouple temperature measurement, and relates to the field of medical instruments, the vein radiofrequency ablation system comprises a host control module, a temperature signal transmission module, a thermocouple temperature measurement module, a radiofrequency energy generation module and a catheter heating module, the thermocouple temperature measurement module at least comprises two parallel thermocouples; the host control module is used for fusing the temperature data of the plurality of temperature measuring points and calculating an average temperature, performing abnormal judgment on the average temperature according to a temperature abnormity automatic power-off control strategy, and dynamically triggering a radio frequency energy closing instruction; on the premise of not changing the original size and structure of the catheter and the operation method of a doctor, in a heating unit with a finite length of the catheter, real-time monitoring of local temperature distribution is realized and temperature abnormity is judged by adopting a multi-point parallel temperature measurement scheme, so that when the temperature of a local temperature measurement point is abnormally increased, radio frequency energy output is quickly closed, and the heating efficiency is improved. Further temperature rise is avoided, and adverse events such as tube burning or blood tube burning are prevented.

The invention discloses an endoscopic soft plasma radiofrequency ablation operation electrode tool bit, and relates to the technical field of minimally invasive medical equipment, the endoscopic soft plasma radiofrequency ablation operation electrode tool bit comprises an electrode assembly, an outer insulation sheath tube and a handle, the electrode assembly comprises an electrode holder, four mounting grooves are formed in the front end of the electrode holder in the circumferential direction of the electrode holder, and an electrode slice is fixedly mounted in each mounting groove; a conductive wire is fixedly arranged at the bottom of each electrode plate, a water outlet hole is formed in the center of the electrode holder in the length direction in a penetrating mode, a slidable cutting electrode is arranged in the water outlet hole, a water outlet gap is reserved between the cutting electrode and the electrode holder, and a ball head is arranged at the front end of the cutting electrode. The ball head is used for lifting tissue in the operation process, and a plurality of water inlets are formed in the rear end of the electrode holder in the circumferential direction. By means of the arranged electrode assembly, minimally invasive operation can be achieved through an endoscope channel under endoscope visibility, and vaporization, cutting, ablation shrinkage and hemostasis can be carried out on pathological tissue parts such as digestive tract mucosa, respiratory tract mucosa and polyp.

A wireless radiofrequency ablation (RFA) system for medical treatment, comprising: an implanted system including: a receiving coil configured to wirelessly receive power, and one or more electrodes operably coupled to said receiving coil to deliver thermal energy to a target when powered by the wirelessly received power; and an external control system including: a radiofrequency (RF) generator, a transmission coil configured to wirelessly transmit power to the receiving coil, and a user interface configured to allow transmit power parameters to be input in order to control the RF generator.

A system for packaging a kit for a radiofrequency ablation procedure protects a radiofrequency ablation kit without compromising its sterile barrier system through the hazards of handling, distribution, and storage. The system includes: an introducer tray configured to hold at least one introducer; a probe tray configured to hold at least one radiofrequency ablation probe; an outer carrier tray, a pouch configured to hold a tubing kit; and a dispenser carton. The introducer tray and the probe tray are held within the outer carrier tray, and the outer carrier tray and the pouch are configured to be held within the dispenser carton. A method of packaging a radiofrequency ablation kit is further described.

The utility model provides a sandbag used after radiofrequency ablation. The sandbag used after radiofrequency ablation comprises a sandbag body. The first fixing part is arranged on the face, close to the skin of the patient, of the sandbag body and comprises a fixing band, the middle of the fixing band is fixedly connected with the sandbag body, the two ends of the fixing band extend out of the sandbag body, the two ends of the fixing band are each provided with a connecting piece, and the face, close to the skin of the patient, of each connecting piece is provided with a sterile patch. And a dustproof film is arranged on the adhesive surface of the sterile patch. According to the application, the possibility of sandbag displacement can be reduced, the risk of local hematoma is reduced, and the workload of nurses is reduced.

The invention discloses a radio frequency treatment comfort optimization method based on multi-modal data driving, and aims at solving the problems that in the prior art, subjective dependence of comfort evaluation is high, and systematic data support and optimization strategies are lacked. A multi-mode sensor is configured through a cloud server, treatment scheme data including thermal imaging, power output and pressure data are collected, and patient condition and environment data obtained from an authorization evaluation platform are combined. A preset comfort level analysis rule set and a multi-dimensional decision table are utilized to perform objective comfort level division and scoring on the treatment process, and based on the division result and the environment data, an ablation system technology is adopted to simulate and calculate the expected influence of different environment parameter combinations so as to determine the comfort level of the treatment process. And generating personalized environmental parameter optimization suggestions under the condition of meeting security constraints. According to the invention, objective and quantitative evaluation and intelligent environment regulation and control of the radio frequency treatment comfort are realized, and the standardization level of treatment and the patient experience are improved.

The application belongs to the technical field of biological medicine, and discloses an oxidation-reduction response type nanoparticle as well as a preparation method and application thereof. The nanoparticle takes a cationic lipid compound and an amphiphilic block polymer containing a disulfide bond as a composite carrier, and co-encapsulates active ingredients siPD-L1 and N-acetyl cysteine. The nanoparticle can be responsively disintegrated in a high-reduction microenvironment of a tumor, synchronously release the two active ingredients, realize the dual effects of reversing immunosuppression and scavenging active oxygen respectively, and synergistically inhibit the growth and metastasis of residual tumors after radiofrequency ablation of liver cancer. The preparation process is simple, the nanoparticle has good stability, high targeting and high biological safety, and provides a new effective strategy for the treatment of residual tumors after radiofrequency ablation of liver cancer.

The invention discloses an automatic DR detection method for an aero-engine conduit, electronic equipment and a storage medium, and the detection method comprises the steps: obtaining 3D point cloud data, carrying out the segmentation detection of the point cloud data, obtaining the coordinates of a grabbing point of a mechanical arm, enabling the mechanical arm to move to a DR detection region after grabbing the conduit, placing a welding line in the center of the DR detection region, and carrying out the detection of the DR. X-rays are started to carry out first DR detection, after the first DR detection is completed, a certain angle is rotated to carry out second DR detection, and after the second DR detection is completed, the mechanical arm moves the catheter to a detected area to be placed. According to the detection method, two DR detection images are obtained for one guide pipe welding seam, the detection efficiency is improved through automatic detection, and the labor intensity during detection is reduced.

The invention discloses a water-cooled needle-shaped radiofrequency ablation electrode which comprises a positive electrode needle body, a needle core, an insulating layer, a negative electrode layer, a negative electrode plate, a handle and a switching button module. The positive electrode needle body is a hollow long needle and is used for puncturing and transmitting radio frequency energy, and a discharge ablation section is arranged at the front end of the positive electrode needle body. The insulating layer and the negative electrode layer are sequentially solidified and attached to the outer side of the needle body to form a bipolar ablation circuit. A switching button module is arranged on the handle and can be switched between the negative electrode layer and the negative electrode plate, so that a bipolar or monopolar ablation circuit is formed. According to the system, two modes can be quickly switched on the same needle body, the supply pressure of cold saline water is adjusted through linkage of the mode detection module, it is ensured that the optimal cooling effect can be obtained in different modes, and the flexibility, accuracy and safety of an operation are improved.

The invention discloses a multi-pole water-cooling radiofrequency ablation needle, and relates to the technical field of medical instruments. Comprising a needle body, the two ends of the needle body are the tip end and the tail end respectively, two electrodes are arranged on the needle body in the axial direction and are the positive electrode and the negative electrode respectively, and the needle body is hollow; the handle is arranged at the tail end of the needle body; the insulating coating is arranged on the surface of the needle body, and the insulating coating is located between the positive electrode and the negative electrode; the power lines are arranged in the needle body, the first ends of the two power lines are connected with the positive electrode and the negative electrode respectively, and the second ends of the two power lines penetrate through the handle to be connected with a power connector. The multiple electrodes are arranged on the needle body, currents can flow between the adjacent currents on the needle body, a negative plate is not needed, the risk of injury to a patient is reduced, meanwhile, energy can be concentrated, the local heat production efficiency is higher, the heat diffusion range is controllable, and small focuses or fine parts can be accurately ablated.

The invention discloses an endoscopic single-electrode plasma radiofrequency ablation operation electrode tool bit, and belongs to the field of digestive and respiratory departments. The electrode tool bit comprises a flexible part, an electrode tip and a handle, one end of the flexible part is connected with the electrode tip, and the other end of the flexible part penetrates through a protective sleeve to be connected with the handle; a water injection connector is arranged on the handle and connected with a water injection hose, and a protective sleeve is arranged at the front end of the handle. A plurality of water outlet holes are formed in the side face of the electrode tip, the flexible part comprises a plastic-coated multi-strand steel wire, a spring tube and an outer sheath tube, and one end of the inner side of the electrode tip extends into the flexible part and is connected with the plastic-coated multi-strand steel wire through a connecting tube; a through groove is formed in the connecting pipe, and cavities are formed between the plastic-coated multi-strand steel wires and the inner wall of the flexible part and between the outer wall of the connecting pipe and the inner wall of the flexible part. The flexible supporting design of the spring tube and the outer sheath tube is combined, the multi-angle steering requirement of an endoscope is met, the endoscope can go deep into a bent cavity or a complex anatomical site, and mechanical damage of rigid instruments to the cavity is avoided.

The invention relates to the field of anti-tumor drugs, and discloses a nano medical drug taking FABP5 as a target as well as a preparation method and application of the nano medical drug. The nano medical drug is prepared by integrating a lipid nano shell with pH response, cycloarginine-glycine-aspartic acid and an erythrocyte membrane, and encapsulating nano particles of superparamagnetic iron oxide and sgFABP5. The nano medical medicine has the application potential of synergistically enhancing the tumor treatment effect after the liver cancer radiofrequency ablation operation.

The invention discloses a flexible anal fistula radiofrequency ablation electrode, which belongs to the technical field of anal fistula disease treatment medical instruments and comprises a flexible electrode, the flexible electrode is connected to a control handle through an electrode terminal, the control handle is connected with a plug through a wire, and the head end of the flexible electrode is arranged as an electrode metal head. The inner side of the electrode metal head is of a hollow structure and is fixedly provided with a thermocouple temperature sensor, the electrode metal head and the thermocouple temperature sensor are connected to the electrode wiring end through a flexible lead assembly, and the outer side of the flexible lead assembly is coated with an inner-layer insulating sleeve used for indicating the insertion depth. And the outer side of the inner-layer insulating sleeve is coated with an outer-layer transparent insulating sleeve of which the head and the tail are tightly attached to the electrode metal head and the electrode wiring end respectively. According to the flexible anal fistula radiofrequency ablation electrode, the clinical requirement of an anal fistula radiofrequency ablation electrode catheter used under an anal fistula mirror can be met, the electrode position and the ablation state can be accurately controlled conveniently, and the ablation treatment effect is guaranteed.

This invention relates to the field of endometrial radiofrequency ablation technology, specifically to an intelligent optimization method for endometrial radiofrequency ablation parameters based on real-time impedance feedback. This method synchronously acquires the instantaneous total power and instantaneous total admittance of the radiofrequency circuit in real time and constructs a sliding time window sequence; it performs local extremum normalization to eliminate dimensional differences, obtaining a two-dimensional phase space point cloud set; it uses the Vietoris-Rips algorithm to extract one-dimensional continuous coherence features, obtaining closed-loop feature values ​​of the point cloud; based on the closed-loop feature values ​​of the point cloud, window energy consumption, and admittance drop, it obtains the tissue dehydration characteristic index; finally, based on the real-time instantaneous total admittance, combined with admittance drop and the dehydration characteristic index, it makes a decision and outputs energy processing instructions. This invention can accurately distinguish between pseudo-high impedance caused by air bubbles and true deep dehydration penetration, ensuring thorough ablation while avoiding the risk of thermal damage.

The invention belongs to the field of biomedical engineering industry, and provides a low-temperature plasma radiofrequency ablation power regulation system based on vocal cord leukoplakia treatment, which comprises the following steps of: firstly, constructing an impedance topographic map of a vocal cord lesion and non-lesion area, planning an ablation route through clustering analysis, monitoring an impedance jump point during an operation, and judging an electrode pollution state; when pollution exists, an impedance jump point-pollutant area coupling model is established, pollution interference is stripped, the real impedance of the tissue is reversely deduced, and then the radiofrequency ablation power is adjusted in real time based on the model; the system realizes dynamic adaptation of power and real impedance of tissue, improves ablation accuracy, reduces normal vocal cord tissue damage, reduces postoperative recurrence rate, and ensures safety and effectiveness of surgery.

This application discloses a method, system, device, and medium for predicting thermal damage from radiofrequency ablation. The method involves inputting multiple ablation parameters to be predicted into a trained bi-branch prediction model. The bi-branch prediction model extracts linear features from the input ablation parameters through a first branch and performs feature cross-transformation on the input ablation parameters through a second branch to obtain nonlinear features. A fusion module then fuses the linear and nonlinear features to output a thermal damage prediction result including both a first and second dimension. In this application, linear feature extraction is performed through the first branch, and feature cross-transformation is performed through the second branch to capture nonlinear features. The fusion of the two branch outputs enables differentiated feature modeling for different dimensions of thermal damage prediction, effectively overcoming the shortcomings of existing models that struggle to accommodate the differences in multi-dimensional damage features, and significantly improving the accuracy and reliability of simultaneous multi-dimensional prediction of thermal damage.

The invention discloses a radio frequency ablation power supply system and a control method, the radio frequency ablation power supply system comprises an AC / DC circuit, a pre-stage DC / DC circuit, a DC / AC circuit, a filter circuit and a radio frequency electrode which are electrically connected in sequence, the radio frequency ablation power supply system further comprises a control circuit, and the control circuit is electrically connected with the pre-stage DC / DC circuit, the DC / AC circuit and the filter circuit. The control circuit is composed of a microcontroller and a logic gate array, due to the fact that the microcontroller controls sequential execution and has many parallel execution requirements for the radiofrequency ablation technology with the high safety requirement, the logic gate array is a field programmable hardware circuit, all signals are executed in parallel, and the safety of the radiofrequency ablation technology is greatly improved. And the requirement of the microcontroller on parallel execution is met.

1. The name of the design product: the graphical user interface of the display of radio frequency ablation operation of electronic equipment. 2. The use of the design product: for an electronic equipment. 3. The design points of the design product: the interface content of the graphical user interface. 4. The picture or photo that best shows the design points: change state figure 5. 5. The electronic equipment is of conventional design, and other views are omitted. 6. The use of the graphical user interface: for parameter setting and information display of radio frequency ablation operation. 7. Other circumstances that need to be explained: the front view of the design product displays the start-up interface, the front view displays the start-up self-checking progress, the system time is automatically detected after starting up, if the system time display error is detected, change state figure 1 is entered, change state figure 1 can set the system time, after clicking confirmation, change state figure 2 is entered, change state figure 2 can turn on / off the key prompt sound and set the screen brightness, after clicking "return", the electrode is automatically verified, if the electrode verification fails, change state figure 3 is entered, change state figure 3 prompts to replace the electrode, after removing the old electrode, change state figure 4 is entered, after installing the electrode and clicking the "confirmation" button in change state figure 4, change state figure 5 is entered, change state figure 5 displays the electrode type and life, after clicking the "confirmation" button in change state figure 5, whether the foot switch is connected is automatically detected, if the foot switch is not connected, change state figure 6 is entered, after connecting the foot switch and clicking "confirmation", change state figure 7 is entered, change state figure 7 can set the parameters, the activation switch on the radio frequency ablation instrument is turned on (not shown in the drawing), change state figure 8 is entered, change state figure 8 displays the treatment interface, if the activation switch is not released after the treatment time is over, change state figure 9 is entered, change state figure 9 prompts to release the activation switch.

This invention provides a vascular interventional robot for transcatheter radiofrequency ablation of the heart, relating to the field of cardiac radiofrequency ablation technology. The vascular interventional robot is configured to acquire historical ablation navigation path planning data and collect real-time ablation vessel data for navigation path planning, forming real-time ablation navigation path data; collect real-time mapping data for abnormal location identification; collect real-time ablation monitoring data and perform real-time monitoring analysis based on process control, forming real-time ablation monitoring results information; and acquire postoperative electrocardiogram data for matching and comparative analysis, forming postoperative test results data. This vascular interventional robot provides a reasonable and easily implemented method for path planning, ensuring smooth and efficient implementation of catheter path navigation in the early stages.

The utility model discloses a plasma radiofrequency ablation electrode which comprises a connecting rod used for being placed in a human body and a handle used for installing the connecting rod, an electrode tip is arranged at the end of the connecting rod, the outer surface of the connecting rod is in sliding connection with a scraping knife tube, one end of the scraping knife tube is placed in the handle, and the handle can drive the scraping knife tube to slide in the axial direction. Meanwhile, the scraping knife tube rotates in the radial direction; when the scraping knife tube is located at the initial position, the scraping knife tube is far away from the electrode tip, so that the electrode tip is arranged outside the scraping knife tube; and when the scraping knife tube is driven to move to the electrode tip, the scraping knife tube covers and contacts with the electrode tip to remove human tissues adhered to the outer surface of the electrode tip. According to the electrode tip cleaning device, the scraping knife tube is controlled by the handle to move in the axial direction and rotate, when the scraping knife tube makes contact with the electrode tip, the outer surface of the electrode tip is cleaned by repeatedly driving the scraping knife tube to move, and an operator does not need to repeatedly take out the electrode tip from the human body, and ablation treatment can be conducted on human tissue for a long time.

The invention relates to the technical field of medical instruments, and particularly discloses an atrial fibrillation patient radiofrequency ablation postoperative compression hemostasis system and method.The atrial fibrillation patient radiofrequency ablation postoperative compression hemostasis system comprises a bandage body, a compression hemostasis assembly is arranged in the bandage body, and the compression hemostasis assembly is connected with an integrated control unit through a connecting assembly; the compression hemostasis assembly comprises a contact layer, a permeation alarm layer, a pressure buffer layer, an air bag compression layer and a flexible tensile strain belt which are sequentially arranged in a layered manner; the connecting assembly comprises an air pipe and a wire. The air pipe is provided with an air pressure sensor, a stop valve and a deflation valve. The integrated control unit comprises a controller, a power supply module, a micro air pump and an alarm circuit, two ends of the air pipe are respectively connected with the air bag pressurizing layer and the micro air pump, and the alarm circuit is connected with the permeation alarm layer; according to the invention, not only can the inflation pressurization and compression force detection functions of the air bag pressurization layer be automatically controlled, but also the functions of errhysis monitoring, intelligent control and remote information transmission are achieved, and the workload of medical staff is effectively reduced.

The utility model discloses a puncture stabilizing support for radiofrequency ablation. The puncture stabilizing support comprises a disc base, a guide rod and a protractor. One end of the guide rod is universally connected to the circle center of the disc base, the other end of the guide rod is supported by the protractor, one end of the protractor circumferentially slides around the circle center on the upper surface of the disc base, and the guide rod is clamped on the protractor and slides along the protractor; according to the utility model, on the basis of the disc base, a 360-degree range on a horizontal plane is covered, and the needle inserting direction on the horizontal plane can be determined through circumferential sliding of the protractor regardless of the determined needle inserting direction; on the basis, the arc-shaped ruler of the protractor is used as a positioning basis in a vertical plane of the guide rod; according to the device, the needle inserting angle is adjusted from the two dimensions of the horizontal plane and the vertical plane, all needle inserting routes are basically covered, any falling line guiding of the puncture needle can be achieved, and compared with a traditional supporting and stabilizing device, a surgeon can keep the needle inserting angle for a long time, and the one-time puncture success rate is increased.

The utility model discloses a thyroid radiofrequency ablation postoperative mirabilite bag, and relates to the technical field of medical nursing materials, an outer-layer bag is filled with a flexible support, an inner-layer bag is divided into a plurality of filling cavities through separation lines, and each filling cavity is used for filling mirabilite; the length direction of the outer layer bag and the length direction of the inner layer bag are the same, the width direction of the outer layer bag and the width direction of the inner layer bag are the same, the outer layer bag and the inner layer bag are mutually stacked and fixed in the thickness direction, a flexible supporting object in the outer layer bag provides certain supporting performance, and the packaging bag is flexible and easy to bend and avoids deformation of filling cavities formed by separation of the inner layer bag. During use, the inner-layer bag is filled with mirabilite, the inner layer is in contact with neck skin, fixing parts used for fixing are arranged at the two ends of the outer-layer bag and / or the two ends of the inner-layer bag, the mirabilite surrounds the neck through opposite connection of the two fixing parts, and the mirabilite is used for making the inner-layer bag in contact with the neck skin to achieve external application. The method is better suitable for external application of the neck saltpeter.

This utility model discloses a foldable lead protective screen for DR (radiofrequency ablation) examinations. The screen comprises a protective screen assembly and electrically controlled support legs. The protective screen assembly includes a main screen and side screens connected by hinges, allowing for folding and unfolding. The main screen has an observation window for medical personnel. The electrically controlled support legs consist of a fixing block, a traction arm, a lower electric push rod, a triangular block, an upper electric push rod, and feet. The extension and retraction of the upper and lower electric push rods drive the traction arm and feet to rotate, enabling the support legs to unfold and retract, providing stable support for the screen and saving space when retracted. The screen is also equipped with omnidirectional casters for easy movement. This technical solution solves the problem of high center of gravity and poor stability of traditional protective screens, improving flexibility and convenience of use while meeting radiation protection requirements.

This invention discloses the preparation and application of radiofrequency thermoresponsive platinum ion crosslinked black phosphorus nanogel. The nanogel has a core-shell structure, comprising a core composed of a radiofrequency thermosensitive agent and chemotherapeutic drugs, and a shell constructed from a thermosensitive nanopolymer. The thermosensitive nanogel BP-Pt@PNA prepared using the above components exhibits radiofrequency thermosensitive properties. Simultaneously, the introduction of the thermosensitive nanopolymer improves the stability of the radiofrequency thermosensitive agent and chemotherapeutic drugs, enabling long-term drug retention and fully leveraging the synergistic effect of non-invasive radiofrequency thermotherapy and chemotherapy. This drug-loaded nanogel can achieve multimodal treatment applications, including non-invasive radiofrequency thermotherapy-chemotherapy synergistic antitumor therapy and invasive radiofrequency ablation-chemotherapy-vascular embolization synergistic antitumor therapy, demonstrating significant clinical translational potential.

The utility model discloses a plasma radiofrequency ablation electrode which comprises an ablation portion of a tubular structure and a holding portion used for installing the ablation portion, the holding portion has a negative pressure extraction function, one end of the ablation portion is provided with an electrode disc and an electrode base used for fixing the electrode disc, the electrode base is of a tubular structure, and the electrode base is provided with a negative pressure extraction function. An electrode catheter with a conductive function is integrally connected to the middle of the electrode disc, an electrode wire is further fixed to the curved surface of the electrode catheter, and the electrode disc is fixed to the end of the ablation part through glue injection between the electrode catheter and the electrode base. Wherein the electrode catheter conveys tissue fluid in a human body and ablates fallen tissues through the electrode disc. The electrode wire is fixed on the electrode catheter, the electrode catheter and the electrode disc are integrally connected, the firmness of the electrode disc is further improved under the fixation of the electrode holder and the electrode wire, and meanwhile, the phenomenon that ablated tissue adheres to the surface of the electrode disc is reduced.

The utility model relates to the technical field of medical instruments, and provides a radiofrequency ablation electrode needle which comprises a handle, a guide needle seat movably arranged on the handle and a connecting structure arranged on the guide needle seat and used for connecting the handle and the guide needle seat, the connecting structure comprises a clamping piece, the clamping piece is provided with an elastic body, and a certain included angle is formed between the elastic body and the clamping piece. The handle is provided with a clamping groove, the clamping groove is provided with a limiting groove corresponding to the elastic body, and the clamping piece is matched with the clamping groove, and the elastic body is in elastic clamping connection with the limiting groove, so that the handle is connected with the guide needle seat. According to the utility model, the handle part and the guide needle seat part are designed in a split manner and are connected through the connecting structure, so that the handle and the guide needle seat are quickly inserted and kept in a locking state, and when one part is damaged, the part is convenient to replace, thereby ensuring that the injection electrode needle can be normally used.

A wireless radiofrequency ablation (RFA) system for medical treatment, comprising: an implanted system including: a receiving coil configured to wirelessly receive power, and one or more electrodes operably coupled to said receiving coil to deliver thermal energy to a target when powered by the wirelessly received power; and an external control system including: a radiofrequency (RF) generator, a transmission coil configured to wirelessly transmit power to the receiving coil, and a user interface configured to allow transmit power parameters to be input in order to control the RF generator.

Disclosed in the present invention is use of a doxorubicin-tetrahedral framework nucleic acid in preparing a drug for reducing electric conduction recurrence after radio frequency catheter ablation. The doxorubicin-tetrahedral framework nucleic acid is prepared from doxorubicin and a tetrahedral framework nucleic acid, and the molar ratio of the doxorubicin to the tetrahedral framework nucleic acid is (80-120):1. The doxorubicin-tetrahedral framework nucleic acid provided by the present invention enables targeted accumulation in an ablation site area after radio frequency catheter ablation, and can successfully induce the death of cells in the area, thereby effectively avoiding electric conduction recurrence caused by cell survival at an ablation site.