38 results about "Bipolar ablation" patented technology

A medical probe assembly, tissue treatment system, and method are provided for ablating tissue. The probe assembly comprises an elongated member and electrode elements mechanically coupled to the distal end of the elongated member. The electrode elements are configurable as two bipolar electrode pairs with a common electrode element. At least one of the electrode elements comprises a plurality of electrodes (such as, e.g., needle electrodes) radially extendable from the elongated member. An ablation source, such as a radio frequency source, can be connected to the probe assembly in order to convey ablation energy to the electrode pairs, either simultaneously or sequentially.

Direct visualization bipolar ablation systems are described which utilize bipolar electrode arrangements. Such assemblies are configured to facilitate the application of bipolar energy delivery, such as RF ablation, to an underlying target tissue for treatment in a controlled manner while directly visualizing the tissue during the bipolar ablation process.

In one embodiment, the present invention provides a bipolar ablation device with multiple needle electrodes that penetrate a desired target tissue. These electrodes may be arranged in a variety of therapeutically effective arrangements, such as a comb-like shape, a multi-needle wheel, or an expanding bow design. By contacting and preferably penetrating the cardiac tissue with bipolar electrodes, a user can more precisely create ablation-induced scarring and thus electrical block at desired target locations without causing unwanted damage and related complications.

Visualization and ablation system variations are described which utilize various tissue ablation arrangements. Such assemblies are configured to facilitate the application of energy delivery, such as RF ablation, to an underlying target tissue for treatment in a controlled manner while directly visualizing the tissue during the bipolar ablation process.

Medical probe kits and methods for treating tissue regions (e.g. tumors) are provided. The kit comprises a delivery cannula and an ablation probe. The delivery cannula comprises a shaft, a lumen extending through the shaft, and a plurality of windows formed through a wall of the shaft in communication with the cannula lumen. The ablation probe is configured to be removably disposed within the cannula lumen. The ablation probe has a shaft and proximal and distal arrays of electrodes that are deployable from the probe shaft. The electrodes of the proximal array are configured to be deployed out from the respective windows when the ablation probe is disposed within the cannula lumen. The electrodes of the distal array may be configured to be deployed out from an axial opening at the distal end of the cannula shaft when the ablation probe is disposed within the cannula lumen. The method may comprise introducing the cannula within a patient, introducing the ablation probe through the cannula, deploying the electrode arrays into contact with the tissue region, and conveying ablation energy to the ablation probe to ablate the tissue region within the electrode arrays.

Methods, systems, and devices for enhancing the efficiency and efficacy of energy delivery and tissue mapping. One system includes a treatment element having a plurality of electrodes and an energy generator that is configured to deliver electric energy pulses to the electrodes in a variety of patterns. For example, electrodes may be arranged in closely spaced pairs. The energy generator may deliver mapping energy to each electrode in each pair individually to map tissue and may deliver ablation energy to the electrodes in each pair together, such that each pair is treated like a single electrode, to deliver ablation energy, such as bipolar ablation energy between adjacent pairs. One system includes at least one concave electrode, the configuration of which concentrates the energy and drives it deeper into the tissue. One system includes neutral electrodes between active electrodes, the energy generator selectively coupling the neutral electrodes to alter the ablation pattern.

A method of ablating a tissue site includes at least two stages. A first stage involves conducting bipolar ablation between a first pair of electrodes situated in an opposing arrangement on opposing sides of the tissue site to form a pair of opposing first stage ablation regions extending from respective sides of the tissue towards the center. A second stage involves conducting bipolar ablation between a second pair of electrodes situated in a diametrical arrangement with respect to the first stage ablation regions, which forms a second stage ablation region intermediate the pair of first stage ablation regions. The second stage completes the ablation through the entire depth of the tissue site. Since the overall process can accommodate incomplete ablation during the first stage, lower power, reduced ablation times or both may be used during the first stage, avoiding overheating and with a decrease in ablated tissue volume.

A medical probe kit and method of treating abnormal tissue within a patient is provided. The kit comprises a cannula having a shaft, a lumen extending through the cannula shaft, and a first ablation electrode disposed on the distal end of the cannula shaft. The cannula may have a handle mounted to the proximal end of the cannula shaft, and an optional fluid delivery port on the handle in fluid communication with the cannula lumen. The kit further comprises an ablation probe configured to be removably disposed within the delivery cannula lumen. The ablation probe has a shaft and a second ablation electrode disposed on a distal end of the probe shaft, wherein the first and second ablation electrodes are arranged in a bipolar configuration. Preferably, the ablation probe is slidable relative to the delivery cannula, whereby the distance between the first and second ablation electrodes can be adjusted. Thus, the delivery cannula can be used to interchangeably deliver the ablation probe and other medical elements, such as a biopsy needle, obturator, and chemotherapeutic agent.

In one embodiment, the present invention provides a bipolar ablation device with multiple needle electrodes that penetrate a desired target tissue. These electrodes may be arranged in a variety of therapeutically effective arrangements, such as a comb-like shape, a multi-needle wheel, or an expanding bow design. By contacting and preferably penetrating the cardiac tissue with bipolar electrodes, a user can more precisely create ablation-induced scarring and thus electrical block at desired target locations without causing unwanted damage and related complications.

The present invention is directed to bipolar ablation systems. A bipolar electrode system for ablation therapy is disclosed, including a pressure-sensitive conducting composite layer and a pair of electrodes in electrical conductive contact or communication with the pressure-sensitive conducting composite layer. Energy (e.g., ablation energy) is delivered via the pressure-sensitive conductive composition when sufficient pressure is applied to transform the pressure-sensitive conductive composite to an electrical conductor. An electrically insulative flexible layer, which may include a passageway for a fill material is also disclosed. In some embodiments, the systems can also be used for targeted delivery of compounds, such as drugs, using a bipolar electrode.

Aspects of the present disclosure are directed to flexible catheters for both electrophysiology mapping and ablation using a high-density array of electrodes. These catheters may be used to detect electrophysiological characteristics of tissue in contact with the electrodes, and conduct monopolar and bipolar ablations of the tissue.

Method and apparatus for ablating target tissue adjacent pulmonary veins of a patient. The ablation device can include a lower jaw assembly including a proximal jaw having a proximal electrode and a distal jaw having a distal electrode, and an upper jaw assembly including an upper jaw having an upper electrode. A proximal actuator can be movable between a first position in which the proximal jaw is open and a second position in which the proximal jaw is clamped with respect to the upper jaw. A distal actuator can be movable between a third position in which the distal jaw is open and a fourth position in which the distal jaw is clamped with respect to the upper jaw.

Method and apparatus for ablating target tissue adjacent pulmonary veins of a patient. The ablation device can include a lower jaw assembly including a proximal jaw having a proximal electrode and a distal jaw having a distal electrode, and an upper jaw assembly including an upper jaw having an upper electrode. A proximal actuator can be movable between a first position in which the proximal jaw is open and a second position in which the proximal jaw is clamped with respect to the upper jaw. A distal actuator can be movable between a third position in which the distal jaw is open and a fourth position in which the distal jaw is clamped with respect to the upper jaw.

Methods, systems, and devices for enhancing the efficiency and efficacy of energy delivery and tissue mapping. One system includes a treatment element having a plurality of electrodes and an energy generator configured to deliver electric energy pulses to the electrodes in a variety of patterns. For example, electrodes may be arranged in closely spaced pairs. The energy generator may deliver mapping energy to each electrode in each pair individually to map tissue and may deliver ablation energy to the electrodes in each pair together, such that each pair is treated like a single electrode, todeliver ablation energy, such as bipolar ablation energy between adjacent pairs. One system includes at least one concave electrode, the configuration of which concentrates the energy and drives it deeper into the tissue. One system includes neutral electrodes between active electrodes, the energy generator selectively coupling the neutral electrodes to alter the ablation pattern.

A balloon expanding renal artery sympathetic nerve ablation catheter comprises spiral electrodes, a balloon, an outer catheter and a functional handle, wherein the spiral electrodes are a pair of electrodes in parallel and are fixed on the outer surface of the balloon, the electrodes can be tightly attached to the blood vessel wall after the balloon is full to carry out double-electrode ablation on the sympathetic nerves on the blood vessel, a plurality of temperature sensors are connected below the electrodes, and the temperature of an ablation area can be monitored in the ablation process in real time. Micropores are formed in the balloon, and cool saline filling cooling can be carried out on the blood vessel tissue outside the ablation area in the ablation process to avoid excessive ablation. One end of the outer catheter can be bent freely, and thus operation and control in the blood vessel can be carried out conveniently. The functional handle can control the bending of the outer catheter, the moving of the balloon relative to the outer catheter and is connected with an external ablation device. According to the balloon expanding renal artery sympathetic nerve ablation catheter, the double-electrode ablation is carried out, ablation points are connected in a spiral mode, and all the sympathetic nerves of the renal artery are isolated effectively. Meanwhile, the ablation temperature is controllable, and due to the fact that the contact between the electrodes and the blood is isolated by the balloon, the purpose of ablating the sympathetic nerves of the renal artery can be achieved with low energy.

A medical probe kit and method of treating abnormal tissue within a patient is provided. The kit comprises a cannula having a shaft, a lumen extending through the cannula shaft, and a first ablation electrode disposed on the distal end of the cannula shaft. The cannula may have a handle mounted to the proximal end of the cannula shaft, and an optional fluid delivery port on the handle in fluid communication with the cannula lumen. The kit further comprises an ablation probe configured to be removably disposed within the delivery cannula lumen. The ablation probe has a shaft and a second ablation electrode disposed on a distal end of the probe shaft, wherein the first and second ablation electrodes are arranged in a bipolar configuration. Preferably, the ablation probe is slidable relative to the delivery cannula, whereby the distance between the first and second ablation electrodes can be adjusted. Thus, the delivery cannula can be used to interchangeably deliver the ablation probe and other medical elements, such as a biopsy needle, obturator, and chemotherapeutic agent.

A catheter adapted for ablation has multiple dedicated irrigation tubings to supply fluid to their respective electrode or set of electrodes. The tubings provide parallel flow pathways through the catheter where irrigation fluid is delivered to irrigated tip and / or ring electrodes which can accomplish uni-polar or bi-polar ablation. Such separate and dedicated fluid pathways allow fluid to be delivered to the corresponding electrode or set of electrodes at different flow rates. An integrated ablation system using such catheter has an ablation energy source and an irrigation pump with multiple pump heads that can operate independently of each other. An integrated irrigation tubing set is included to extend between the fluid source and the catheter, with each pump head being able to act on a different tubing that delivers fluid to a different electrode or set of electrodes.

The present disclosure describes devices and methods for treating disorders in a hollow body organ by ablating the tissue therein. At least one set of bipolar electrodes is deployed in the hollow bodyorgan to contact the inner wall of the organ. In the deployed position, each positive electrode is positioned in a location substantially opposite each negative electrode. The tissue contact areas ofthe positive and negative electrodes are substantially the same and the electrodes are separated from one another by a distance of at least 10 times the width of each of the electrodes. The electrodes thereby produce lesions that are substantially identical to one another and also similar to those produced with mono-polar electrodes. The electrodes are used to produce an ablation pattern that canelectrically isolate regions of the hollow body organ, thereby treating the disorder(s).

Medical probe kits and methods for treating tissue regions (e.g. tumors) are provided. The kit comprises a delivery cannula and an ablation probe. The delivery cannula comprises a shaft, a lumen extending through the shaft, and a plurality of windows formed through a wall of the shaft in communication with the cannula lumen. The ablation probe is configured to be removably disposed within the cannula lumen. The ablation probe has a shaft and proximal and distal arrays of electrodes that are deployable from the probe shaft. The electrodes of the proximal array are configured to be deployed out from the respective windows when the ablation probe is disposed within the cannula lumen. The electrodes of the distal array may be configured to be deployed out from an axial opening at the distal end of the cannula shaft when the ablation probe is disposed within the cannula lumen. The method may comprise introducing the cannula within a patient, introducing the ablation probe through the cannula, deploying the electrode arrays into contact with the tissue region, and conveying ablation energy to the ablation probe to ablate the tissue region within the electrode arrays.

The invention discloses a bipolar ablation system with dual perfusion and ECG output. The system comprises a single bipolar radio frequency system and a perfusion system. A control MCU in the single bipolar radio frequency system isolates a transmission controller and a radio frequency power amplifier driving circuit through a control signal. A radio frequency power amplifier circuit is connectedwith the radio frequency power amplifier driving circuit and a power amplifier power supply. A radio frequency output end is connected with a first ablation catheter output channel, a second ablationcatheter output channel and a back polar plate through a single bipolar channel switching circuit. The control MCU is connected with a filter circuit through a filter enable relay. The filter circuitis connected with an ECG analog port. The perfusion system comprises first and second perfusion pumps which are communicatively connected with the control MCU in the single bipolar radio frequency system through a perfusion pump isolation communication controller respectively. The bipolar ablation system controls the corresponding perfusion pump to output a high quality ECG signal according to different radio frequency outputs, can improve the ablation efficiency, and at the same time can reduce the surgical risk.

The invention discloses a water-cooling internal circulation type bipolar ablation needle for electroporation. The water-cooling internal circulation type bipolar ablation needle comprises a front electrode tube, a front insulating tube, a rear electrode tube and an outer insulating tube, wherein the front insulating tube sleeves the front electrode tube; a first end of the front electrode tube extends out of the front insulating tube to form a needle head part; a second end of the front electrode tube is connected with a first cable; the rear electrode tube sleeves the front insulating tube; the outer insulating tube sleeves the rear electrode tube; a first end of the rear electrode tube extends out of the outer insulating tube and has a discharging distance with a part, extending out of the front insulating tube, of the front electrode tube; and a second end of the rear electrode tube is connected with a second cable. According to the water-cooling internal circulation type bipolar ablation needle disclosed by the invention, the technical effects of reducing the needle distribution quantity of the electroporation ablation needle and simplifying needle distribution operation are realized; and the problems in the prior art that when electroporation ablation is adopted, a plurality of ablation needles need to be distributed, needle distribution is usually difficult at lesion positions or in narrow spaces of dense blood vessels, and the cooling efficiency of the electroporation ablation needle is relatively low are solved.

The invention discloses a novel bipolar ablation electrode. The electrode comprises an electrode tip, an electrode stem, a handle assembly, a weep pipe assembly and a cable assembly. The novel bipolarablation electrode is characterized in that the handle part of the electrode stem is connected with a built-in jack in the front end of the handle assembly; a built-in jack in the tail end of the handle assembly is connected with a buckle plug-in type cable assembly; a hollow tube structure is arranged in the electrode stem; a sealing ring (6) and a weeping tube are arranged between the electrodestem and the handle assembly; the sealing ring is connected with a capillary tube (4) at one end of the weeping tube arranged in the handle assembly; and a parallel silicone tube (12) is led out fromthe other end of the capillary tube (4) to be connected with the weeping tube assembly to form a built-in weeping pipeline. The novel bipolar ablation electrode is innovative in structure, reasonablein design, safe to use, convenient to operate, capable of achieving modular batch production, capable of saving cost and environmentally friendly in production process. The novel bipolar ablation electrode is suitable for medical instrument production enterprises to provide safe, reliable, convenient and fast hemostasis for surgical operations in batches.

Electrosurgical fibroid ablation systems and methods employ a probe (300) having at least two electrodes (320, 330) to perform bipolar ablation. The probe (300) is inserted into the uterine fibroid (50) along the long axis (B) direction of the ellipsoid fibroid (50) (direction approximately parallel to the uterine wall (14)) to enter the fibroid (50). Inserting the probe (300) in this direction facilitates the ablation of the fibroid (50) with a single probe (300) penetration, since the ablated area is often within a region having an ellipsoidal shape that aligns with that of the fibroid (50). Growth in volume. Furthermore, any scars (170B) left by the procedure often run in a direction parallel to the uterine wall (14), and are thus less likely to spread and cause rupture of the uterine wall (14) during pregnancy.

This application discloses an electroporation water-cooled internal circulation bipolar ablation needle, which includes a front electrode tube, a front insulating tube, a rear electrode tube and an outer insulating tube; the front insulating tube is sleeved on the front electrode tube, and the front electrode tube The first end extends out of the front insulating tube and forms the needle head, the second end of the front electrode tube is connected with the first cable; the rear electrode tube is sleeved on the front insulating tube, the outer insulating tube is sleeved on the rear electrode tube, and the rear electrode tube The first end of the first end extends out of the outer insulating tube, and has a discharge distance from the part of the front electrode tube extending out of the front insulating tube; the second end of the rear electrode tube is connected with a second cable. This application achieves the technical effect of reducing the number of needles for electroporation ablation needles and simplifying the operation of needles, and solves the problem of using multiple ablation needles in the related art when electroporation ablation is used in the lesion position or narrow space of dense blood vessels. Internally, there are often difficulties in needle placement, and there is also the problem of low cooling efficiency for electroporation ablation needles.