6results about How to "Low affinity" patented technology

This invention relates to the field of polymer materials technology, specifically disclosing a flame-retardant thermoplastic elastomer compound and its preparation method. The flame-retardant thermoplastic elastomer compound comprises 50-80 parts SEBS, 10-30 parts PP, 5-15 parts compatibilizer, 10-30 parts composite flame retardant, 3-10 parts plasticizer, 0.2-1 parts antioxidant, and 0.1-0.5 parts lubricant. The composite flame retardant is prepared by reacting and mixing an intumescent flame retardant, barium metaphosphate, boron nitride, triallyl isocyanurate, and SEBS. The flame-retardant thermoplastic elastomer compound of this application possesses good flame retardancy, mechanical properties, and water resistance stability.

This invention discloses a class of polypeptide ligands that can specifically bind to and / or significantly promote the assembly of Holliday linkers and their applications, belonging to the field of biomedical technology. The general formula for the amino acid sequence of the polypeptide ligand is: AX₄BQX₃CXn, where A and B are each independently selected from any one of phenylalanine, tryptophan, tyrosine, lysine, and arginine; C is selected from any one of arginine and lysine; X represents any amino acid; and n is an integer ranging from 0 to 4. The advantages of this invention are: the polypeptide provided by this invention has a high affinity for Holliday linkers (HJs), a strong ability to promote HJ formation, and exhibits certain antitumor activity against human liver cancer cells A549.

The present disclosure relates to a positive electrode active material, a battery, and a method for manufacturing a positive electrode active material. The positive electrode active material includes an olivine-type phosphate compound including at least one selected from lithium manganese phosphate and lithium manganese iron phosphate, and a coating that coats at least a portion of a surface of the positive electrode active material and includes carbon and iron.

The application discloses an integrated composite acid emulsion applied to fracturing fluid and acid liquid and a preparation method thereof, and belongs to the technical field of oil and gas field exploitation. The preparation steps of the emulsion are as follows: S1, organic solvent and composite emulsifier are mixed, stirred, dispersed and uniformly distributed to obtain an oil phase; S2, quaternary ammonium salt unsaturated monomer, sodium benzenesulfonate unsaturated monomer, methacryloyloxyethyl phosphate and a complexing agent are added into water, mixed uniformly and adjusted to have a pH value of 7-9 to obtain an aqueous phase; S3, under the condition of stirring, the aqueous phase is added dropwise into the oil phase to form a water-in-oil emulsion; S4, after nitrogen is passed through the water-in-oil emulsion to remove oxygen, an initiator is added, the temperature is increased to 40-60 DEG C, and stirring reaction is carried out for 4-8 h to obtain the integrated composite acid emulsion. The composite acid emulsion prepared by the inverse emulsion polymerization method has the characteristics of strong thickening, high resistance, high temperature resistance, crosslinking and on-line viscosity change when applied to water and acid liquid, and is an integrated composite acid thickening agent emulsion suitable for fracturing fluid and acid liquid.

The present invention relates to a glycosylated Fc variant with improved selective binding affinity to FcγRIIIa. Novel human antibody Fc domain variants of the present invention have reduced binding affinity to FcγRIIIb, which is an immuno-inhibitory receptor, compared to antibodies approved as conventional antibody therapeutic agents, and have improved binding affinity to FcγRIIIa (an increase in the A / I ratio), which is an immuno-activating receptor, and thus have a significantly improved ability to induce ADCC, and have the effect of maximizing the immune action mechanism of therapeutic protein drugs, and thus can be effectively used as antibody drugs.

This invention discloses an organofluorosilicone emulsion deepening agent, which is made from the following raw materials in parts by weight: 3-9 parts of hexamethylcyclotrisiloxane, 2-4 parts of trifluoropropylmethylcyclotrisiloxane, 1-3 parts of hexamethyldisiloxane, 3-9 parts of vinyldisiloxane, 1-3 parts of emulsifier, 0.1-0.6 parts of catalyst, and 2-6 parts of acrylate monomer. The organofluorosilicone monomer is prepared by ring-opening reaction of hexamethylcyclotrisiloxane, trifluoropropylmethylcyclotrisiloxane, and hexamethyldisiloxane under the action of trifluoromethanesulfonic acid catalyst. Then, the emulsifier is used to emulsify the monomer to obtain organofluorosilicone emulsion I. This invention has a simple preparation method, can reduce dye affinity, and inhibit dye migration. Furthermore, by changing the amount of emulsifier, the particle size of the emulsion can be adjusted, and emulsions of different particle sizes can be mixed together to form a film with different roughness, thus achieving a deepening effect.