The invention discloses an evaluating system of depressive disorder degree quantization. The system comprises an electrocardio and pulse wave integral detection device, a data transmission device and a data processing platform. The invention further discloses an evaluating method of depressive disorder degree quantization. The method comprises the following steps that firstly, human physiological information under different states is acquired through a multi-state comprehensive test platform; secondly; HRV characteristic parameters under the different states are obtained on the basis of the heart rate variability analysis principle; thirdly, the function balance states of sympathetic nerves and pneumogastric nerves in the automatic nervous system are evaluated; fourthly, a depressive disorder degree quantization evaluation model is built, and the depressive disorder degree level of a tested person is evaluated fast and objectively. The system and method belong to the technical field of computer-aided diagnosis, depressive disorder degree quantization evaluation is achieved, the blank of the technical field of depressive disorder inspection is filled up, and the system and method are easy and convenient to implement, save medical resources and have the good clinic practicality.