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149 results about "Physiological reaction" patented technology

Intelligent dialogue system and method based on AI multi-mode large model

The invention relates to an intelligent dialogue system and method based on an AI multi-mode large model. The method comprises the following steps: collecting biological characteristic data of a user in real time; cloning a personalized expression mode of the user by using the generative adversarial network; driving the audio avatar to perform multi-round dialogue interaction with the user, capturing a real-time physiological signal of the user through an expression recognition module, and generating a dynamic response content suggestion in combination with a dialogue context; and analyzing the interaction process based on the reinforcement learning model. The multi-modal deep fusion of the voice rhythm features, the language structure features and the facial dynamic features is realized, so that the limitation of single-modal or simple feature splicing in the prior art is broken through, the emotional state of the user can be accurately and comprehensively captured, the intention is expressed and the fine physiological reaction is expressed, and the user experience is improved. And a solid foundation is laid for constructing high-fidelity user representation.
Owner:NANCHANG YIJING INFORMATION TECH CO LTD

Interactive interface design parameterization method guided by tactile feedback

The invention provides an interactive interface design parameterization method guided by tactile feedback. The method comprises the following steps: acquiring physiological features, use habits and use scene information of a user, and presetting basic tactile feedback parameters according to a scene-parameter mapping rule; during interaction, touch parameters such as vibration frequency and amplitude are dynamically adjusted based on user operation behaviors, physiological reactions and scenes by using a deep learning model; and meanwhile, a multi-modal parameter fusion model is established, so that tactile, visual and auditory parameters have a synergistic effect, for example, when a button is clicked, the three parameters are mutually associated to enhance a feedback effect. After the operation is completed, the feedback effect is evaluated through objective indexes such as the subjective score of the user and the operation accuracy, and the user personalized model and the parameter adjustment model are optimized. According to the method, the problems that traditional parameters are fixed, and multi-modal fusion is insufficient are solved, accurate and personalized man-machine interaction is achieved, and the user experience is improved.
Owner:CITY COLLEGE WENZHOU UNIV

Sensory nerve quantitative detection method and system based on electroencephalogram characteristics

The invention discloses a sensory nerve quantitative detection method and system based on electroencephalogram characteristics, and relates to the technical field of electroencephalogram measurement, and the method comprises the steps: building detection files in one-to-one correspondence with users; respectively wearing the current stimulation module and the electroencephalogram detection module on the wrist and the head of the user; current stimulation is applied to a user step by step through a current stimulation module, and gamma waves in electroencephalogram signals of the user are collected in real time through an electroencephalogram detection module; gamma waves in the electroencephalogram signals of the user are analyzed, and whether the intensity of current applied to the user by the current stimulation module exceeds a physical stimulation sensing threshold value of the subject or not is judged; and analyzing severity grades of sensory disorders. The method has the advantages that detection is carried out through brain wave signals without relying on subjective feedback of a patient, interference of factors such as emotion and psychology is avoided, and even a special patient who cannot carry out self-perception report can complete sensory nerve quantitative detection through objective physiological reaction of brain waves.
Owner:HEFEI ZHONGKE HEALTHCARE MEDICAL TECHNOLOGY CO LTD

Method and system for merging bio-electrospraying, cell electrospinning merged with 3D multimaterial microfluidic bioprinting fabricate human tissues for drug discovery applications

PendingUS20250243452A1Bioreactor/fermenter combinationsBiological substance pretreatmentsHuman bodyAlternatives to animal testing
The present invention provides a method and system for fabricating complex human tissues by integrating bio-electrospraying, cell electrospinning merged with 3D multi material microfluidic bioprinting, and future additions of magnetic and acoustic levitation technologies. The fabricated tissues serve as an alternative to animal testing in drug discovery processes, aiding in the prediction of human physiological responses to various drug compounds.
Owner:OUROBIONICS BV

Classroom student concentration degree monitoring system and method based on computer vision

The invention provides a classroom student concentration degree monitoring system and method based on computer vision. The system comprises a vision collection module, an edge calculation unit and a cloud analysis platform. A multi-dimensional sensing mode combining head posture analysis, eye state tracking, facial expression recognition and body movement detection is adopted to evaluate the concentration degree, through a dynamic feature fusion mechanism, the system can intelligently adjust the weight ratio of different modal features, the limitation of single-dimensional analysis in a traditional method is effectively solved, and the accuracy of the system is improved. The system adopts edge calculation and cloud analysis, ensures high efficiency of data processing, ensures reliability of complex algorithm operation, and has important value for improving classroom teaching quality and learning efficiency. According to the invention, through multi-modal visual analysis, behavior characteristics and physiological reactions of students in class are monitored in real time, the concentration level of the students is comprehensively evaluated, and objective teaching feedback and improvement basis are provided for teachers.
Owner:SUZHOU HAIZHOU INTELLIGENT TECHNOLOGY CO LTD

Exertion-driven physiological monitoring and prediction method and system

Automated systems and methods are presented for determining the physiological response of human or suitable animal subjects to physical exertion. The methods and systems can include monitoring sensors that capture the motion of the subject along with corresponding physiological data, and can track such motion for the duration of a period of physical exertion. The system is able to acquire an initial stream of physiological data from the subject during a range of physical exertion activities that are representative of the events intended to be monitored with the proposed method and system, enabling a corresponding dynamic physiological response model to be created. The motion tracking system and physiological response model can then be used to predict the physiological response to physical exertion events under a prescribed framework, including applications during real-time event monitoring.
Owner:SALUTRON INC

Remote data acquisition and analysis method and system for stroller

The invention provides a remote data acquisition and analysis method and system for a baby stroller, and the method comprises the steps: synchronously acquiring environmental stimulation and passenger physiological reaction data through multiple modules on the baby stroller, locally processing the environmental data into cumulative stress indexes, and processing the physiological data such as sound production into state classification labels. And when the passenger has negative stress states such as crying, screaming and the like, the system automatically packs the accumulated stress index sequence in the previous period of time to form a stress event data packet. And the data packet and baseline data in a normal state are transmitted to a remote server together, and a specific environment mode causing the negative stress of the passenger is identified through comparative analysis. According to the method, through event-triggered data acquisition and comparative analysis, specific external factors causing discomfort of infants can be accurately identified and understood.
Owner:HUBEI RUIZHI CHILDRENS PROD CO LTD

Acute pain assessment method and system based on EDA signal

ActiveCN121867707AReal-time quantitative assessmentReal-time analysis and real-time quantitative evaluationSensorsDiagnostic recording/measuringPattern recognitionSympathetic nerve
The invention relates to the technical field of signal analysis, in particular to an acute pain assessment method and system based on an EDA signal, and the method comprises the following steps: collecting a skin electrical activity EDA signal of a subject; calculating an individual time-varying sympathetic nerve activity TVSymp curve; the method comprises the following steps: constructing a priori knowledge base containing a standardized pain response sympathetic nerve SpainSymp template; inputting the EDA signal and the individual TVSymp curve into a PCVAE model, fusing features and decoupling the features into pain common features and individual specific features; carrying out pain intensity classification, and reconstructing and generating a standardized SpainSymp curve of which individual specific characteristics are removed; and outputting the pain intensity classification result and the dynamic change trend of the standardized SpainSymp curve in real time. By adopting the method, the pain-induced physiological reaction and individual baseline variation can be effectively decoupled and separated from the mixed EDA signal, the interference of individual difference is avoided, and the method has the characteristics of high accuracy and strong real-time performance.
Owner:GUANGDONG UNIV OF TECH

VR motion sickness state detection method based on multi-modal physiological parameter fusion

The invention is applied to the technical field of intelligent health and biological feedback, and discloses a VR motion sickness state detection method based on multi-modal physiological parameter fusion, and the detection method comprises the following steps: S1, carrying out data acquisition through a data acquisition module: fixing an electrocardiosignal around a heart in the form of three-lead number electrode points, setting the sampling frequency to be 1024Hz, and setting the sampling time to be 1h; the skin electric signal acquisition is arranged at the tail end of a finger in a 2-lead number electrode point form, the sampling frequency is 64Hz, and the central electric signal and the skin electric signal in the VR operation process are respectively acquired from a heart signal and a finger skin surface layer signal of an operator. According to the VR motion sickness state detection method based on multi-modal physiological parameter fusion, the activity of an autonomic nervous system and the activity of a sympathetic nerve are reflected through electrocardio signals and skin electric signals respectively, physiological reactions of motion sickness are captured from different dimensions, and physiological state information when the motion sickness occurs is extracted more accurately through multi-modal fusion analysis.
Owner:SHENZHEN UNIV

Physiologically-driven standardized intelligent patient simulation system

The invention discloses a physiologically-driven standardized intelligent simulation patient system, which comprises an adult simulation patient, a computer, a computer, a computer, a computer, a computer, a computer, a computer and a computer, wherein the adult simulation patient is made of a simulation man-made high polymer material, is environment-friendly and pollution-free, has obvious anatomical marks, touches two nipples, ribs, sternum and xiphoid processes, is flexible in joints, and realizes various operation body positions; wherein the physiological data comprises the heart rate, the blood pressure and the respiratory rate, the data is combined with a built-in physiological model to simulate the physiological state of a patient in real time, a monitor is simulated, real-time physiological data monitoring and feedback are provided, and the vital signs, the heart rate, the blood pressure and the oxyhemoglobin saturation of the simulated patient are displayed; the system has strong physiologically-driven standardized intelligent comprehensive simulation patient, can perform situational teaching according to a real clinical environment, effectively assesses the clinical thinking and personal operation skills of students, can greatly improve the team cooperation spirit of the students, and simulates the real physiological response and clinical scene.
Owner:WEIFANG MEDICAL UNIV

Acupuncture data monitoring system based on brain-computer interface

The invention discloses an acupuncture data monitoring system based on a brain-computer interface, which belongs to the field of acupuncture data monitoring and comprises a data acquisition module, an acupuncture difference analysis module, a brain wave judgment module and an acupuncture scheme dynamic adjustment and feedback module. The data acquisition module is used for acquiring WorldClim temperature data, Ketz climate classification data, brain wave basic value data of people of different regions and ages, real-time electroencephalogram signals of patients and acupuncture and moxibustion parameters; according to the acupuncture data monitoring system based on the brain-computer interface, acupuncture sensitivity degrees, brain wave threshold values and acupuncture suggestions of patients under different resident climates can be rapidly obtained, accurate matching of personalized treatment schemes is achieved, pertinence and effectiveness of acupuncture treatment are improved, meanwhile, doctors are assisted in dynamically adjusting strategies according to physiological responses of the patients, and the accuracy of acupuncture treatment is improved. And the treatment process is simplified.
Owner:山东海天智能工程有限公司

Adaptive stimulation device with integrated feedback mechanism and proxy measurement

PCT designated stageWO2026097013A1Machine learningExternal electrodesStimulus patternPhysical medicine and rehabilitation
An adaptive stimulation system optimizes pain relief, pleasure enhancement, and healing through closed-loop physiological effectiveness monitoring. The system comprises a stimulation device, sensors measuring physiological responses indicative of stimulation effectiveness, and a processor implementing real-time adaptive control. The system measures unconscious physiological responses that users cannot voluntarily control and involuntary reactions to objectively assess whether stimulation achieves desired outcomes. Through proxy learning, system sensors correlate with sophisticated clinical measurements via machine learning, enabling clinical-grade optimization using accessible devices. The system continuously explores multidimensional parameter spaces to discover optimal stimulation patterns personalized to individual users, automatically adapting parameters based on measured physiological effectiveness rather than subjective user control or preset patterns. Applications include medical devices, wellness products, and intimate stimulation systems.
Owner:HABERMAN SETH

Kit and method for administering an active ingredient to elicit a physiological response

A kit (100) and method (200) are provided for administering an active ingredient (112) to a subject to elicit a response. The kit comprises a first container (110) with an active ingredient (112) and a second container (120) with an adjuvant (122). The containers permit the ingredients to be admixed to form a compounded preparation for delivery into the subject's tissue. The active ingredient can comprise an allergen. The kit can also include temperature control and mixing components, potentially involving a third container (130). The method comprises providing the kit (100), admixing the ingredients, and injecting the compounded form into the subject's tissue such as a lymph node. The injection can be monitored and repeated. The approach can elicit various responses such as desensitization according to the type of active ingredient used. Overall, the kit (100) and method (200) provide targeted delivery of active ingredients to efficiently provoke a localized response in the subject.
Owner:ALLERGY UNLIMITED LLC

Adaptive artificial intelligence system for identifying behaviors associated with mental illness and modifying treatment plans based on emergent recognition of aberrant reactions

One or more embodiments described herein relate to predicting, using adaptive artificial intelligence techniques, typical and aberrant physiological reactions of a patient to psychiatric counseling. Treatment plans can be determined and calculated based on previously-gathered demographic and / or biometric data, and / or modifications to treatment plans can be determined and / or implemented based on emergent recognition of reaction types, such as reclassifying reactions that would previously have been deemed typical as aberrant (or vice versa).
Owner:GRANATO GROUP INC

Portable equipment with artificial intelligence for monitoring respiration and heart condition and system for this

PendingDE102025126833A1Health-index calculationInertial sensorsCardiac statusControl system
A portable respiration and cardiac monitoring device includes a detection finger band and a wearable heart rate relay watch. The detection finger band comprises a light emission unit for emitting a detection light beam and a response light receiver unit for receiving a physiological response signal. The detection light beam enters the user's fingertip to generate the physiological response signal. The wearable heart rate relay watch is connected to the detection finger band via a connecting cable. The wearable heart rate relay watch receives the physiological response signal and includes a gravitational accelerometer. The gravitational accelerometer detects the acceleration of the wearable heart rate relay watch to generate an acceleration detection signal. A detection datum comprises the acceleration detection signal and the corresponding physiological response signal.The wearable heart rate relay watch transmits the detection data to an external device. A wearable, artificial intelligence-based system for monitoring respiration and cardiac status includes a control system that communicates with the wearable respiration and cardiac status monitoring device.
Owner:CHANG KUO YUAN

Visceral function detection device, control method thereof, diet management method and system

This application relates to a device for detecting organ function and its control method, as well as a dietary management method and system, belonging to the technical field of medical device testing. The control method compares and analyzes changes in the microscopic features of the same area of ​​the tongue before and after eating, and calculates the corresponding metabolic index change rate, constructing a mapping relationship between the tongue's microscopic morphology and organ function, providing a basis for assessing internal physiological function through external characterization. Simultaneously, the dietary management method uses physiological responses before and after eating as real-time biofeedback signals to generate dynamically adjusted dietary management plans, forming a personalized health management closed loop of "monitoring-assessment-intervention-remonitoring," achieving precise adaptive adjustment of intervention strategies.
Owner:HANGZHOU XINBENLE CULTURAL INTELLIGENT TECHNOLOGY CO LTD

An environment perception-based smart watch multi-source data fusion method and system

PendingCN122634468APersonalizationOriginal data
The application relates to the technical field of intelligent sensors and big data processing, in particular to a smart watch multi-source data fusion method and system based on environment sensing. The method comprises the following steps: obtaining an original data set through a smart watch; generating a data frame sequence according to a preprocessing result of the original data set, and generating a fusion feature vector based on the data frame sequence; inputting each fusion feature vector into a preset health mode classification model, and outputting an initial recognition result; generating a health risk level and an environmental influence factor according to the initial recognition result, and outputting user feedback information; extracting features such as a heart rate variation interval, a body temperature change rate and an air quality fluctuation cycle, constructing a fusion feature vector, combining a pre-trained health mode classification system, analyzing a linkage relationship between environmental changes and physiological reactions, and accurately identifying a stress mode caused by environmental pollution; and finally outputting personalized health prompt information based on a risk score mechanism and a historical mode library.
Owner:SHENZHEN KINGWEAR TECH DEV

Interaction events based on physiological response to illumination

Various implementations disclosed herein include devices, systems, and methods that determine an interaction event during presentation of an interaction element. For example, an example process may include obtaining physiological data associated with a pupil during presentation of an interaction element, determining, based on the obtained physiological data, a pupillary response during the presentation of the interaction element, determining that the pupillary response corresponds to attention response characteristics associated with attention of a region of the regions of the interaction element based on the different illumination characteristics of the regions, and determining an interaction event during the presentation of the interaction element based on determining that the pupillary response corresponds to directing attention to the region during the presentation of the interaction element.
Owner:APPLE INC

Food quantification method and system for digestive nursing patient

The invention relates to the technical field of data processing and data analysis, in particular to a food quantification method and system for a digestive nursing patient, and the method comprises the following steps: obtaining multi-source heterogeneous time sequence data related to the adjustment of the food of the digestive nursing patient, and carrying out the integration and standardization processing of the obtained multi-source heterogeneous time sequence data, the data after integration and standardization processing are obtained; on the basis of the integrated and normalized data, individual time sequence correlation characteristics between meal adjustment events and subsequent physiological reactions or symptom changes of the digestive nursing patient are mined, and the individual time sequence correlation characteristics are obtained; the problems that real-time or near-real-time individualized adjustment is difficult to realize and an effective feedback optimization mechanism is lacked in the prior art are solved by acquiring multi-source data, mining individualized time sequence correlation features, setting dynamic influence factor weights, generating individualized suggestions and optimizing the weights based on feedback iteration.
Owner:南京市高淳人民医院

Momentary Stress Algorithm for a Wearable Computing Device

A method of monitoring stress of a user includes receiving a plurality of time-series data inputs from a plurality of biometric sensor electrodes of a wearable computing device. The time-series data inputs includes continuous electrodermal activity data and at least one of heart rate data, skin temperature data, and heart rate variability data. The method also includes processing the time-series data inputs using a plurality of filtering techniques in sequence. Further, the method includes selecting a model from a plurality of models based on types of data inputs received as the time-series data inputs to calculate an indicator of a physiological response of the user at a certain time. Thus, the selected model is tailored to use all of the time-series data inputs in the calculation of the indicator of the physiological response. Further, the method includes controlling a function of the device when the indicator of the physiological response exceeds a threshold.
Owner:GOOGLE LLC

Systems, devices and methods for anxiety treatment using vestibular nerve stimulation

Methods, systems and devices are provided to stimulate the vestibular system in such a way as to influence the neurological components of the autonomic nervous system and reduce an anxiety level in a subject. A device with one or more electrodes placed over a subject's scalp provides vestibular nerve stimulation (VeNS) to the vestibular nerve, which is then carried into the vestibular nucleus in the brainstem and thereafter transmitted to the neurological components of the autonomic nervous system to reduce a physiological reaction to an anxiety event. The characteristics of the stimulation signal and duration of the treatment are configured to allow the treatment to be delivered before, during or after an anxiety event to potentially prevent or at the very least reduce an anxiety response in the subject.
Owner:NEUROVALENS LTD

Physiologic response monitor mouth wearable

PendingUS20260248442A1DentistryBiomedical engineering
Various components, methods, and systems are provided herein for monitoring physiological responses associated with force-impact events using a mouth-wearable sensing device positioned within an oral cavity of a subject. In some embodiments, the device integrates inertial sensing, force sensing, temperature sensing, and optical physiological sensing on a compact intraoral substrate and transmits physiological data wirelessly to an external computing device for analysis and reporting. In some embodiments, the mouth-wearable sensing device is customized using intraoral scan data to generate a three-dimensional oral cavity model and to position one or more sensors to align with anatomical landmarks when worn.
Owner:UNIV OF SOUTH FLORIDA

A chronic disease risk management and control method based on community gridding

This invention relates to the field of health and medical data processing technology, and particularly to a method for chronic disease risk management based on community grids. The method includes constructing an initial spatial environmental potential field based on point-of-interest weights; calculating the risk exposure integral sequence and instantaneous potential gradient by combining user trajectories; if the gradient exceeds a threshold, adjusting parameters and using a matrix contour algorithm to extract stress-related abnormal motifs from physiological monitoring data; reconstructing the potential field by statistically analyzing the frequency of group motif attacks; finally, calculating the cross-correlation between the exposure integral and the attack frequency sequence to obtain a causal index; and combining this with health records to output a chronic disease risk rating and intervention instructions. In this invention, by introducing an instantaneous potential gradient to feedforward and regulate the extraction parameters of physiological motifs, the technical problem of traditional fixed-parameter sampling easily missing environmental stress physiological responses is solved, enabling the underlying algorithm to accurately capture users' stress-related abnormal physiological motifs during sudden environmental changes.
Owner:MINXIAN PEOPLES HOSPITAL

Intravenous anesthesia instantaneous dose regulation and control method and device based on operation stage recognition

The invention relates to an intravenous anesthesia instantaneous dose regulation and control method and device based on operation stage recognition, and belongs to the technical field of medical big data and intelligent control. A deep learning model is used for carrying out high-dimensional feature fusion and time sequence mode analysis, current and future surgical operation stages are dynamically and accurately identified and predicted, an ideal target drug concentration is dynamically set by querying a built-in knowledge base generated by big data mining, and a model prediction controller is driven to calculate an optimal instant infusion rate, so that the optimal instant infusion rate is obtained. Advanced and accurate drug regulation and control are achieved, a closed-loop feedback mechanism is introduced, parameters are adaptively adjusted on line according to actual physiological reactions, and control individualization and safety are ensured. According to the invention, the crossing from passive feedback to active predictive control is realized, the stability and safety of anesthesia depth are obviously improved, and the method has great clinical application value.
Owner:PEKING UNIVERSITY THIRD HOSPITAL (THE THIRD CLINICAL MEDICAL SCHOOL OF PEKING UNIVERSITY)

Device for mitigating motion sickness and other responses to inconsistent sensory information

Embodiments disclosed herein mitigate motion sickness by disrupting, controlling, or influencing anatomy of the vestibular system. An embodiment may induce vibrations in the vestibular system, including otoliths and / or semicircular canals of the inner ear, causing noisy or unreliable sensory information to be sent to the brain from the vestibular system. Due to the noisy or unreliable quality, the brain, as part of a normal physiological response, may rely less on sensory information from the vestibular system and rely more on other sources, thereby mitigating the motion sickness response, vertigo, vestibular migraines, and other physiological responses to inconsistent sensory information. Vibrations in the vestibular system may be induced by an agitator placed on an individual's head near the vestibular system, or by a transducer placed near the eardrum or directly on an individual's head. Some embodiments may optionally include implantable components in addition to extracorporeal components.
Owner:OTOLITH SOUND INC

Unsafe behavior monitoring equipment for coal mine operating personnel

The utility model belongs to the field of safety of coal mine workers, particularly relates to equipment for monitoring unsafe behaviors of coal mine workers, and aims to solve the problems of low sponge falling speed, poor simulation authenticity, single simulation form, low collapse scene reduction degree, high safety and the like in the prior art that a fixed rod is rotated to drive a connecting rope to enable a sponge to fall off. In order to solve the problems that in the prior art, in the prior art, behaviors of workers in an unsafe scene are difficult to effectively monitor, according to the scheme, a clamping assembly is used for containing a sponge block, when the sponge block is suddenly opened, the scene of coal mine collapse can be modeled, meanwhile, recovery and re-release of the sponge block are achieved through a winding roller, and the situation that the sponge block is damaged is avoided. The device has the advantages that the simulation effect of collapse is more real, vibration in coal mine operation, coal mine collapse, poisonous gas leakage and various sounds in a collapse site are simulated, the simulation scene is more real, and the authenticity of physiological response and psychological change data of coal mine workers in an unsafe behavior environment is effectively improved.
Owner:CHINA NAT COAL GROUP CORP

Enhanced secure authentication system utilizing dynamic avatar interaction and advanced multimodal biometric analysis

PendingUS20250363197A1Digital data authenticationEngineeringIdentity fraud
This invention extends its capabilities in digital authentication by incorporating sophisticated behavioral and fraud detection analyses alongside dynamic avatar interaction and multimodal biometric assessments. By analyzing a wide range of user behaviors, physiological responses, and interaction nuances, the system provides a comprehensive solution that not only detects traditional forms of identity fraud but also subtle signs of coercion or evasion. This multifaceted approach ensures a highly secure and user-responsive authentication process, making it exceedingly difficult for fraudsters to manipulate or bypass.
Owner:ABRAMS LUKE +1

Exercise load control device and exercise load control method

The present invention is provided with: an exercise physiological response acquisition unit (105) that acquires data indicating an exercise physiological response of an exerciser; a control parameter calculation unit (106) that calculates a control parameter for controlling an exercise load on the basis of the data indicating the exercise physiological response acquired by the exercise physiological response acquisition unit (105); and an exercise load control unit (107) that, on the basis of the data indicating the exercise physiological response acquired by the exercise physiological response acquisition unit (105) and the control parameter calculated by the control parameter calculation unit (106), uses the control parameter to control the exercise load such that the exercise physiological response reaches a target value.
Owner:MITSUBISHI ELECTRIC ENG CO LTD +1

Adaptive radiotherapy system with biophysical real-time monitoring of tissue response

An adaptive radiotherapy system (100) with biophysical real-time monitoring of the tissue response, wherein the system (100) comprises: a module (1) for real-time biophysical tissue response monitoring, configured to acquire live data on the physiological response and tissue response from a treatment area of ​​a patient during irradiation; a module (2) for localizing patient anatomy and motion detection, configured to detect position changes, organ movements and target shifts in real time; an engine (3) for adaptive treatment planning and dose recalculation, configured to dynamically update a radiotherapy treatment plan based on data received from the module (1) for real-time biophysical monitoring of tissue response and from the module (2) for localizing patient anatomy and motion detection; an engine for predictive modeling of tissue response (4) configured to estimate short-term tissue response, tumor response and normal tissue tolerance using patient data from current and previous sessions; an interface for controlling and modulating the beam (5) which is functionally coupled to a radiation delivery device and configured to modify one or more beam parameters in real time; a safety check and treatment lock control (6) configured to compare current treatment conditions with one or more allowable thresholds and selectively interrupt, stop, or release radiation delivery; and a module (7) for clinical review, data logging and treatment evaluation, configured to store treatment response data, generate session-related adjustment protocols and provide one or more recommendations for subsequent fractions, wherein the system (100) adaptively modifies the radiation output in response to continuously monitored biophysical tissue conditions of the patient.
Owner:ABDELMOHSEN SHAIMAA ABDELRAOF MOHAMED +6

Health condition treatment via adaptive loop stimulation patch

A system for real-time management of a health condition in a patient. The system includes a wearable sensor including at least one sensor for measuring physiological responses, electrodes configured to stimulate and record a nerve, and a sensor processing module for receiving the physiological responses and the nerve response and transmitting them to a computing device, as well as actuate the electrodes to stimulate the nerve. The system further includes the computing device configured to actuate the sensor device to deliver an initial stimulation, receive the physiological responses and the nerve response, generate a response profile specific to the patient, actuate the sensor device to deliver subsequent stimulations according to the response profile, receive subsequent physiological responses and a subsequent nerve response, and adjust, based on a change, the response profile. The steps of subsequent stimulation, receiving responses, and adjusting the response profile may be repeated until a target point.
Owner:RGT UNIV OF CALIFORNIA