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A pharmaceutical composition and its use in the preparation of a medicament for inhibiting ethanol self-administration preference
Pending
CN122097379A
Nervous disorder
Heterocyclic compound active ingredients
Alcohol ethyl
Pharmaceutical drug
The application discloses a kind of pharmaceutical composition and its purposes in preparation for inhibiting the autonomous intake preference of
ethanol
. The pharmaceutical composition includes
lorcaserin
and
midazolam
. The pharmaceutical composition for inhibiting the autonomous intake preference of
ethanol
provided by the application can effectively reduce the desire of body to
alcohol
, is used to treat
alcohol
dependence, and has significant long-acting characteristics. When the pharmaceutical composition is administered to mice, the
absolute amount
of active
ethanol
intake of mice and the relative proportion of ethanol intake compared with the amount of drinking water can be significantly reduced, and the
inhibitory effect
can last at least 6 days, which is expected to update the
treatment plan
for
alcohol
addiction
in clinic.
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Owner:
XUZHOU MEDICAL UNIVERSITY
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Pharmaceutical Substances
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Inhibitory effect
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