The invention discloses a multiple-working-condition hydraulic design method for a guide vane type 
centrifugal pump. The multiple-working-condition hydraulic design method for the guide vane type 
centrifugal pump mainly comprises the following steps that 
specific speed solution is conducted on the design working conditions of the guide vane type 
centrifugal pump, and the design working condition with the 
specific speed as an intermediate 
specific speed is selected and designed; multiple-scheme design is conducted on an 
impeller and guide vanes through an experiment design method, and the CFturbo style is adopted; 
mesh generation is conducted on a model, numerical 
simulation is conducted on a scheme through CFX, the lift and the efficiency value are read, and function fitting is conducted between the lift and a flow; function fitting is conducted between the lift and the flow of a design parameter point, the coefficient of a fitting function is used as a design goal, input main geometrical parameters are used as input values, an approximate 
response model is established through the 
Kriging model, rapid computation is conducted on the approximate 
response model through a multiple-target 
genetic algorithm, and then the optimal value is obtained. By the adoption of the multiple-working-condition hydraulic design method for the guide vane type centrifugal pump, the requirement for multiple-working-condition hydraulic design of the guide vane type centrifugal pump can be met; the multiple-working-condition hydraulic design method for the guide vane type centrifugal pump can also be used for multiple-working-condition hydraulic design of other guide vane type centrifugal pumps.