5results about How to "Improve lung function" patented technology

The application belongs to the technical field of traditional Chinese medicines, and particularly relates to a traditional Chinese medicine compound for treating pulmonary fibrosis of diabetes and application thereof. The traditional Chinese medicine compound comprises 70-90 parts of Huangqi, 20-40 parts of Danshen, 10-30 parts of Chuanxiong, 20-40 parts of Beishashen and 40-60 parts of Shanyao. The application also discloses application of the traditional Chinese medicine compound in preparation of a medicine for treating pulmonary fibrosis of diabetes of the type of deficiency of both qi and yin and blood stasis. The traditional Chinese medicine compound has reasonable formula, and uses the traditional Chinese medicine theory scientifically. The raw materials are matched according to the principle of monarch, minister, assistant and guide, and the traditional Chinese medicines are synergistically used, so that the traditional Chinese medicine compound can not only supplement deficiency of both qi and yin of diabetes, but also dredge stasis of collaterals of long-term disease, and achieve good clinical test effect by considering both the symptoms and the root cause.

The invention belongs to the technical field of traditional Chinese medicines, and particularly relates to a traditional Chinese medicine composition capable of eliminating pulmonary nodules and a preparation method thereof. The traditional Chinese medicine comprises astragalus membranaceus, codonopsis pilosula, poria cocos, roasted rhizoma atractylodis macrocephalae, honey-fried licorice root and the like, treats both symptoms and root causes, breaks through the limitation of traditional pulmonary nodule treatment, and can accelerate blood flow and condition physique while treating pulmonary nodule; the traditional operation method is broken through by eliminating phlegm, removing dampness, promoting blood circulation to remove blood stasis and softening hardness to dissipate stagnation, and pulmonary nodules caused by imbalance of viscera and imbalance of yin and yang can be adjusted; according to the traditional Chinese medicine composition, a plurality of medicines are combined and comprehensively attacked, the lung function is improved, yin-yang balance is corrected, and nodules are eliminated.

The application belongs to the technical field of traditional Chinese medicines, and particularly discloses a traditional Chinese medicine composition for treating Klebsiella pneumoniae pneumonia and a preparation method thereof. The traditional Chinese medicine composition is prepared from eight raw medicinal materials of Zhejiang fritillary bulb, white mulberry bark, Chinese plume-pod seed, dandelion, platycodon root, lily, apricot kernel and poria cocos. The composition has the effects of promoting lung and clearing heat, relieving cough and reducing sputum, and strengthening body resistance and eliminating pathogenic factors. Pharmacodynamic experiments show that the composition has a significant therapeutic effect on Klebsiella pneumoniae pneumonia.

This invention provides a DNA nanowire capable of breaching the mucus barrier in COPD, its preparation method, and its application in the preparation of drugs for preventing and treating lung infections, belonging to the field of nanomedicine technology. The DNA nanowire of this invention utilizes a strongly positively charged antibiotic AMK and a divalent cation Mg²⁺. + The synergistic effect of streptavidin and biotin forms a stable DX tile structure. Subsequently, utilizing the high affinity between streptavidin and biotin, the biotin-modified Biotin-NAC is precisely anchored to the 5' end of the M chain, achieving a combined loading of mucolysis and subsequent immunomodulatory functions. Through a strain-induced azido-alkyne cycloaddition reaction, the DBCO-modified L chain is covalently linked to the azido-modified neutrophil chemotactic peptide Ac-PGP to form a stable triazole structure, endowing the platform with chemotactic ability for CXCR2-overexpressing neutrophils. The DNA nanowires of this invention can effectively prevent and treat lung infections in COPD patients.

This invention provides an application of 1-O-acetyl-Inula japonica lactone, which is used to prepare drugs for improving acute lung injury. This invention utilizes network pharmacology, molecular docking, and molecular dynamics simulations to analyze that the Keap1-Nrf2 signaling pathway is a key potential target for Inula japonica in treating acute lung injury. The characteristic component of Inula japonica, 1-O-acetyl-Inula japonica lactone, exerts antioxidant and anti-inflammatory effects by targeting Keap1 and activating the Nrf2 signaling pathway. This invention provides important evidence for the application and new drug development of 1-O-acetyl-Inula japonica lactone.