120results about How to "Promote infiltration" patented technology

The invention discloses a porous substrate reinforced anion exchange membrane and a preparation method and application thereof, and relates to the technical field of anion exchange membranes. The porous substrate reinforced anion exchange membrane is prepared by the following steps: uniformly mixing a polyarylene alkylene type cationic polymer solution and a C1-C10 alcohol solvent, then coating two sides of a porous substrate with the mixture, and drying to obtain the porous substrate reinforced anion exchange membrane. And removing the solvent to obtain the product. According to the method, the porous substrate can be well infiltrated by the cationic polymer solution without pre-treating the porous substrate, so that the porous substrate reinforced anion exchange membrane with a sandwich-like structure is obtained. The film has outstanding swelling resistance and excellent mechanical properties, has good electrochemical properties, and has good application prospects in alkaline film energy conversion devices.

The invention discloses a centella asiatica plant extraction repairing agent and application thereof in cosmetics. The centella asiatica plant extraction repairing agent comprises the following components: an olive leaf extract, a centella asiatica root extract and an oat kernel extract. According to the preparation process of the centella asiatica plant extraction repairing agent, plant water-soluble active ingredients are obtained by adopting enzymolysis and alcohol extraction modes, plant oil-soluble active ingredients are obtained by adopting critical CO2 extraction, and then a novel preparation is prepared by adopting an ultrasonic emulsification technology, so that the repairing agent can permeate into skin cuticles more easily, the effect of active matters can be brought into full play, and the repairing agent has a good application prospect. When the composition is applied to cosmetics, a good repairing effect can be realized.

The invention provides a tumor cell exosome, an anti-tumor immune drug delivery system and a preparation method and application of the anti-tumor immune drug delivery system, the tumor cell exosome is derived from starved and stimulated tumor cells, the tumor cell exosome is coated with nano drug particles for delivery, and the exosome has the effects of enhancing immune cell infiltration and remodeling an immune microenvironment; due to the homing effect of the exosome, the medicine and the exosome are more easily accumulated in the tumor, and the targeting property is improved; due to coating and camouflage of the biological membrane of the exosome membrane, the exosome membrane is prevented from being recognized, attacked and removed by an organism, and the biological safety is improved, so that the exosome and the nano-drug act on the tumor together to achieve a synergistic effect.

The invention relates to the technical field of reverse osmosis membranes, in particular to a polyamide reverse osmosis membrane for high-salinity wastewater treatment and a preparation method of the polyamide reverse osmosis membrane. The invention solves the problem that the polyamide reverse osmosis membrane cannot give consideration to both desalination rate and water flux. The polyamide reverse osmosis membrane comprises a polyester non-woven fabric layer, a polysulfone porous layer, a transition layer and a polyamide layer. The polysulfone porous layer is prepared, and the modified pore-forming agent is added to improve the water flux of the reverse osmosis membrane; the hydrophilicity of the reverse osmosis membrane is improved by preparing the transition layer and adding a hydrophilic auxiliary agent when the polyamide layer is prepared; the flux attenuation rate of the polyamide reverse osmosis membrane is reduced by preparing the polyamide layer; the desalination rate of the reverse osmosis membrane is improved by introducing a composite ion complexing agent and graphene quantum dots into the polyamide layer.

The invention provides an aluminum-based composite material reinforced by nickel-coated silicon carbide through a magnetron sputtering dry method and a preparation process of the aluminum-based composite material, and relates to the technical field of metal-based composite materials and advanced electronic packaging thermal management materials. Comprising the following steps that S1, silicon carbide particles coated with nickel through a magnetron sputtering dry method and aluminum powder are put into a mold to be subjected to compression molding, and an initial blank is obtained; and S2, the initial blank prepared in the step S1 is placed in a re-pressing sintering furnace under the inert gas protection condition, continuous re-pressing is conducted under the temperature condition ranging from the temperature lower than the aluminum melting point by 50 DEG C to the temperature higher than the aluminum melting point by 200 DEG C, and the nickel-coated silicon carbide reinforced aluminum-based composite material obtained through the magnetron sputtering dry method is obtained. The aluminum-based composite material reinforced by magnetron sputtering dry nickel-coated silicon carbide disclosed by the invention is excellent in heat-conducting property and mechanical property and long in service life.

The invention provides a composite gel electrolyte membrane and a preparation method thereof, belongs to the technical field of solid-state batteries, and aims to solve the technical problem of low ionic conductivity of solid-state electrolyte. The preparation method of the composite gel electrolyte membrane comprises the following steps: (1) dissolving a polymer precursor, an ionic liquid and a composite lithium salt in an organic solvent to obtain a gel electrolyte precursor solution; (2) dispersing an inorganic oxide on the surface of the polymer matrix, and performing hot-pressing compounding to obtain an oxide-based membrane; and (3) coating the surface of the oxide-based membrane with the gel electrolyte precursor solution, and carrying out curing treatment to obtain the composite gel electrolyte membrane. The composite gel electrolyte membrane provided by the invention is prepared in a simple in-situ polymerization manner, forms an organic / inorganic compact composite membrane, forms dual-ion synergy, has good mechanical elasticity, high ionic conductivity and high flame retardance, and can effectively inhibit the growth and puncture of lithium dendrites in a lithium metal negative electrode.

The invention relates to the technical field of medicine, in particular to a preparation method and application of a photodynamic-chemotherapy nano platform targeting tumor endogenous YAP1. The nano platform is hollow mesoporous silica nanoparticles (M (at) O-VNPs) loaded with oxaliplatin and VP of a macrophage membrane coating. The preparation method comprises the following steps: S1, synthesizing hollow mesoporous silica nanoparticles; s2, preparing the organic silicon nanoparticles loaded with the Verteporfin, and preparing the organic silicon nanoparticles loaded with the Verteporfin; s3, loading of the oxaliplatin; and S4, extraction and coating of a macrophage membrane. According to the invention, the macrophage membrane wrapped on the surface of the nano platform is utilized to provide good tumor targeting for the M (at) O-VNPs, and by camouflaging the macrophage membrane and the M (at) O-VNPs, not only are recognition and removal of an organism immune system successfully avoided, but also Verteporfin (VP) and oxaliplatin (OXA) can be delivered to a tumor site in a targeting manner, so that the tumor targeting of the drug is remarkably enhanced, and the drug has a good application prospect. The non-specific distribution in healthy tissues is reduced, and the systemic toxicity is reduced.

The invention provides a negative pole piece and a lithium ion battery, the negative pole piece comprises a current collector, a first electrode material layer and a second electrode material layer, the first electrode material layer and the second electrode material layer are sequentially stacked on the current collector along a direction far away from the current collector, and the first electrode material layer and the second electrode material layer both comprise active materials. The active material comprises first active material particles and second active material particles, the particle size of the first active material particles is larger than that of the second active material particles, and the total mass of the first active material particles in the first electrode material layer is smaller than that of the second active material particles; the total mass of the first active material particles in the second electrode material layer is greater than the total mass of the second active material particles. The cycle performance and the electrical performance of the battery cell can be improved by regulating and controlling the ratio of the first active material particles to the second active material particles in the first electrode material layer and the second electrode material layer.

The invention provides a negative electrode plate and a preparation method thereof, and the preparation method specifically comprises the following steps: (1) providing first negative electrode slurry containing a first binder and second negative electrode slurry containing a second binder; (2) coating one side or two sides of a current collector with the first negative electrode slurry, and coating the first negative electrode slurry with the second negative electrode slurry; (3) drying and rolling to obtain a negative pole piece; the swelling ratio of the first binder is S1, the swelling ratio of the second binder is S2, and 1.5 < = S2 / S1 < = 4. According to the invention, the performance of the battery cell is improved by reducing the adverse effect of overlarge compaction of the surface of the pole piece on electrolyte infiltration. According to the method for preparing the negative pole piece, new equipment and production procedures do not need to be added, the method is compatible with an existing process technology, and the effect is obviously improved.

The invention belongs to the technical field of talc, and provides a method for detecting fluorescent substances in talc raw ore, which comprises the following steps: S1, carrying out ball milling on the talc raw ore in a ball mill, sieving to obtain sieved powder, and adding deionized water into the sieved powder to obtain slurry; s2, adding the slurry into the mixture to enable the pH value of the slurry to be 5, stirring, and standing in a water bath for 2-3 hours to obtain a first precipitate; s3, adding a thiourea-ascorbic acid solution into the first precipitate to obtain a second precipitate; and S4, carrying out secondary ball milling on the second precipitate, and spreading the second precipitate in an enamel plate to detect whether the talc raw ore contains the fluorescent substances or not. The hydrochloric acid can dissolve quartz and mica to avoid generation of background fluorescence or quenching effect, and the nonionic surfactant polyethylene glycol can be adsorbed on the surface of the mineral to reduce interfacial tension, so that the hydrochloric acid is easier to infiltrate tiny pores, the pit defect caused by local over-corrosion is reduced, the pickling uniformity is improved, and the detection sensitivity is improved.

The invention discloses a cooling assembly, a heat dissipation device and a vehicle. The cooling assembly comprises a shell and a partition plate. The partition plate is arranged in the shell to divide the shell into a first sub-cavity and a second sub-cavity, and a plurality of spraying holes are formed in the partition plate to spray a cooling medium in the first sub-cavity to the second sub-cavity, so that bubbles generated by the second sub-cavity are separated from the shell. Therefore, the cooling medium is introduced through the first sub-cavity and forms jet flow in the jet hole, so that the jet flow can break bubbles generated by the second sub-cavity, the bubbles are changed into small bubbles, the bubbles are prevented from gathering to form large bubbles, the cooling medium can always infiltrate the bottom surface of the circulation channel, and the heat dissipation capability of the cooling assembly is enhanced.

The invention discloses a porous carbon fiber supported black phosphorus / nitrogen-doped carbon composite material as well as a preparation method and application thereof, and belongs to the field of new energy materials and devices. A nitrogen-doped carbon-coated porous carbon fiber conductive frame is prepared by using a metal-assisted chemical etching technology, then red phosphorus is converted into black phosphorus by adopting a solvothermal and confinement growth strategy, and the black phosphorus grows in a pore channel of the nitrogen-doped carbon-coated porous carbon fiber frame in an in-situ confinement manner, so that the high-performance self-supporting phosphorus / carbon heterostructure electrode material is constructed and obtained. The three-dimensional nitrogen-doped carbon-coated porous carbon fiber conductive framework realizes high-speed electron / ion transmission and limits the expansion of the electrode structure; abundant nitrogen doping defects are beneficial to abundant reaction active sites and enhancement of reaction kinetics; the in-situ formed phosphorus / carbon heterogeneous interface can promote electron transfer and ion diffusion, stabilize the electrode structure and realize stable, rapid and reversible sodium storage.

The present application relates to the field of pharmaceutical preparation and nanomedicine, and particularly relates to a kind of nano-drug composition, its combined drug delivery system and application.The nano-drug composition comprises alpha 1-AR blocker and amphiphilic nano-carrier;The alpha 1-AR blocker is loaded in the hydrophobic core formed by amphiphilic nano-carrier;The alpha 1-AR blocker is selected from one or more of prazosin, terazosin, doxazosin;The average particle size of the nano-drug composition is 220-260 nm, the polydispersity index is less than 0.3, and the encapsulation efficiency is greater than 50%.The nano-drug composition of the present application has dual functions of anti-tumor proliferation and immune microenvironment remodeling, improves the dispersion stability of the drug in physiological medium, effectively reduces the in vivo clearance rate, prolongs the circulation time, and realizes the efficient in vivo delivery of the drug.The preparation process of the nano-preparation is stable and can be produced on a large scale.

The application discloses a kind of nano-permeable resin coating for construction in high-humidity water environment of desulfurization chimney lining anticorrosion, chimney lining includes reducing agent layer, reinforcing agent layer, primer layer, topcoat layer in turn from inside to outside, nano-permeable resin primer and topcoat can be permeated into the concrete matrix to form the anticorrosion layer of "matrix-coating", "mixing element integration", so that it not only has excellent acid corrosion resistance, but also has high and low temperature alternation and airflow scouring performance, solve the problem that chimney lining anticorrosion layer fails due to stress corrosion, also has good construction performance, solve the difficult problem that chimney lining anticorrosion layer construction period is short.

The application discloses a kind of high-efficiency super-soft organic solar cell of top incidence structure, it includes flexible substrate, anode, anode modification layer, active layer, cathode modification layer, cathode and antireflection layer from bottom to top, wherein the cathode is based on the transparent electrode of ultrathin silver.Especially by preferred cathode modification layer and introducing not more than 2nm thick gold as seed layer, make ultrathin silver surface more smooth and uniform, the transparent electrode can further improve the photoelectric energy conversion efficiency (PCE) of organic solar cell.Meanwhile, using the wide adaptability of top incidence structure to different substrates, the organic solar cell can also achieve comparable PCE (17.32%) with mm level rigid glass substrate on the polyimide flexible substrate with thickness of only 1.3 μm.Therefore, the highest efficiency of super-soft organic solar cell so far is obtained, and the highest power density (39.72W g ‑1 ) in all photovoltaic technologies at present is also obtained.

This application discloses an electrolyte solute, its preparation method, and its application. The electrolyte solute comprises an olefinic cyclohexene carboxylic acid compound obtained by the reaction of conjugated diene carboxylic acids. The conjugated diene carboxylic acid includes at least one compound having the structure shown in Formula III: wherein X and Y are each independently selected from H, -RO-COOH, substituted or unsubstituted C1-10 saturated hydrocarbon groups, etc., and at least one of X and Y is -RO-COOH; RO represents a directly bonded or C1-10 saturated hydrocarbon group. The electrolyte solute of this application, comprising an olefinic cyclohexene carboxylic acid compound with unsaturated hydrocarbon functional groups, can both improve the flash voltage of the electrolyte and maintain low viscosity and high conductivity.

The utility model discloses a polygonal road structure which comprises a roadbed structure, an assembly type concrete prefabricated slab is laid on the top of the roadbed structure, and the roadbed structure comprises a plain soil covering layer laid on the ground in a tamping mode and a stone powder laying layer covering the left side of the surface of the top of the plain soil covering layer. The right side of the top surface of the plain soil covering layer is covered with the dry hard ash filling layer. According to the scheme, through trapezoidal concave-convex interlocking and L-shaped hooking, quick assembly and top leveling are achieved, the leveling procedure is reduced, the laying efficiency is improved, a reinforcing mesh is arranged in the prefabricated slab, mechanical meshing and curbstone coating are combined, and the compression resistance and displacement resistance are enhanced; the symmetrical prefabricated plates support length expansion, and the curbstone notches and the protruding blocks are coupled to adapt to various road layouts. The water permeable bricks are higher than the prefabricated slabs and matched with the dry hard ash filling layer, rainwater infiltration is promoted, waterlogging is relieved in combination with the green belt design, and the service life of the plates is prolonged through the double-lock-catch design.

The application discloses application of human umbilical cord-derived mesenchymal stem cell apoptosis vesicles in preparation of drugs for treating uveitis, and relates to the technical field of biological medicine.The application first applies human umbilical cord-derived mesenchymal stem cell apoptosis vesicles to preparation of drugs for treating uveitis, and the human umbilical cord-derived mesenchymal stem cell apoptosis vesicles can significantly improve eye inflammation and retinal tissue damage of a mouse with uveitis, significantly reduce the proportion of Th1 and Th17 proinflammatory cells in a spleen, and increase the proportion of Treg anti-inflammatory cells.Compared with stem cell exosomes, the human umbilical cord-derived mesenchymal stem cell apoptosis vesicles can more effectively reduce inflammatory cell infiltration in a vitreous cavity and a retinal layer, relieve retinal folds and detachment, reduce damage to photoreceptor cells, reduce fundus clinical scores and retinal pathological scores, and the immunoregulation effect is significantly better than that of stem cell exosomes, and the human umbilical cord-derived mesenchymal stem cell apoptosis vesicles overcome technical bottlenecks of storage, transportation and batch consistency of living cell preparations, and provide a safer, more stable and more efficient new strategy for uveitis treatment.

The utility model provides a kind of farmland type ecological buffer zone structure, it is related to agricultural ecological environment management technical field, including land buffer area one, ecological regulation pond, land buffer area two and concave green land, land buffer area one, ecological regulation pond, land buffer area two and concave green land are sequentially distributed from farmland side to river embankment side, land buffer area one and land buffer area two are planted with arbor shrub and grass flower mat, the ecological regulation pond is sequentially provided with impermeable layer, adsorption layer and plant layer from bottom to top, the concave green land is laid with buffer base, the concave green land is planted with herbaceous plant and shrub. This structure effectively intercepts farmland non-point source pollution, reduces river pollutant, helps to strengthen river self-purification capacity, promotes aquatic animal and plant diversity development, and guarantees ecological benefit to play well.

The invention discloses a novel application of a tetrastigma planicaule water extract in preparation of a medicine for preventing or treating hyperuricemia and related metabolic diseases, the treatment effect and action mechanism of the tetrastigma planicaule water extract on HUA are discussed by establishing a PO and HX induced rat HUA model, and the result shows that the tetrastigma planicaule water extract can be used for preparing a medicine for preventing or treating hyperuricemia and related metabolic diseases. The tetrastigma planicaule water extract can reduce the uric acid level in a rat body by adjusting uric acid transporter protein, promote uric acid excretion, remarkably improve liver and kidney injury and inflammatory cell infiltration induced by PO and HX, relieve a series of reactions caused by hyperuricemia and improve the curative effect of hyperuricemia. And a theoretical basis and a clinical basis are provided for new medicines for clinically treating hyperuricemia and related metabolic diseases thereof.

A multifunctional rainwater garden system for urban inland inundation treatment comprises a rainwater garden, an ecological pool and an underground water storage tank. The rainwater garden is arranged along the hardened ground, the ecological pool is arranged at the low-lying position of the inner side of the rainwater garden, a clear water tank of the underground water storage tank is connected with the ecological pool through a perforated pipe at the bottom, filtered rainwater is collected through the perforated pipe, and a rainwater tank of the underground water storage tank is connected with the ecological pool through an overflow grating and a pipeline on the bank. Overflowed rainwater is collected through the overflow pipe. According to the system, the rainwater infiltration speed and infiltration amount can be increased, the rainwater quality is preliminarily purified, the purified rainwater is collected for simple life use and flower and tree irrigation, the rainwater utilization rate is increased, rainfall flood regulation and storage and rainwater drainage are integrated, the drainage pressure of urban pipelines is relieved, and the risk and probability of urban inland inundation are reduced.

The utility model provides a permeable pavement structure suitable for a high underground water level area, which is a laminated structure and sequentially comprises a soil base layer, an impermeable layer, a drainage base layer, a leveling layer and a permeable surface layer from bottom to top, permeable geotextile is arranged between the drainage base layer and the leveling layer; the drainage base layer is of an assembly type splicing structure and is composed of an assembly type concrete frame with the thickness being 200-300 mm, graded broken stone and a drainage pipe. According to the utility model, infiltrated rainwater in the laminated structure layer can be drained in time, and the effect of reducing the runoff peak value of the permeable pavement is fully exerted; the anti-seepage layer can effectively prevent rainwater runoff from seeping into underground water or underground water from seeping into facilities, so that the risk of polluting the underground water is avoided; and the structure is simple, construction is convenient, and good economical efficiency and practicability are achieved.

The present invention relates to 2-heteroaryl-3-oxo-2,3-dihydropyridazine-4-carboxamide compounds of general formula (i), wherein x, r1, r2, r3, r4, and r5 are as defined in the description. The invention also relates to methods for preparing said compounds, intermediate compounds useful for preparing said compounds, pharmaceutical compositions and combinations comprising said compounds, and the use of said compounds for manufacturing pharmaceutical compositions for the treatment or prophylaxis of diseases, in particular cancer or diseases with dysregulation of immune responses or other disorders associated with aberrant AHR signals, as monotherapy or in combination with other active ingredients.

The application discloses a method for preparing lithium pre-doped amine coordination manganese iron phosphate precursor from lithium manganese iron phosphate, and belongs to the field of battery recycling. The method comprises the following steps: stirring and reacting lithium manganese iron phosphate battery material with a high-valence iron salt solution and a surfactant, and filtering to obtain filtrate and phosphorus iron residue; mixing the filtrate with a phosphate, adjusting the pH of the solution to 2-6, then mixing with an oxidizing agent A, and adding a mixed solution containing an organic amine compound to perform nucleation precipitation reaction, and aging to obtain the lithium pre-doped amine coordination manganese iron phosphate precursor. The application utilizes the surfactant and the high-valence iron salt to efficiently replace divalent iron under acid-free or weak acid conditions, generates a metal solution containing Li + , Fe 2+ , Mn 2+ , performs oxidation to form nucleation precipitation, adds an organic amine compound to control the morphology of the generated particles in the solution, generates the lithium-doped amine coordination manganese iron phosphate precursor, the reaction condition is mild, the energy consumption in the treatment process is low, and the economic utilization value of a manganese byproduct is improved.

The invention relates to the technical field of garden seedling raising, in particular to garden integrated seedling raising equipment which comprises cultivation boxes, a partition cavity is formed in the middle of an inner cavity of each cultivation box, cultivation cavities are formed in the left side and the right side of each partition cavity respectively, the interiors of the two cultivation cavities are both filled with water, and liquid guide units are installed on the cultivation boxes respectively. Each liquid guide unit is used for being communicated with the interior of the corresponding cultivation cavity, a cultivation device is installed above the cultivation cavity, a plurality of seedling raising units are installed on the cultivation device, and plant seedlings are cultivated in each seedling raising unit. According to the garden integrated seedling raising equipment, integrated cultivation of garden seedlings can be achieved, simultaneous cultivation of multiple seedlings can be completed at the same time in the cultivation process, the seedlings can be protected during cultivation, damage to seedling root systems is greatly reduced during transplanting after the seedlings grow up, and the survival rate of seedling transplanting is indirectly increased.

The invention discloses a preparation method of an insulating hot wire and a preparation device of the insulating hot wire, and the preparation method of the insulating hot wire comprises the following steps: S1, coating the outer surface of the hot wire which is wound into a required shape with an insulating layer blank; and S2, electrifying the hot wire processed in the step S1, and directly heating the hot wire and the insulating layer blank coated on the hot wire by utilizing the heat effect of the current, so that the insulating layer blank is sintered and attached to the hot wire, and the insulating hot wire is further prepared. The insulating layer of the insulating hot wire prepared by the preparation method is not easy to fall off, the service life of the product is longer, the heating power is greatly reduced, the energy consumption is low, the process time is short, the requirement on equipment is lower, the insulating hot wire is easy to obtain, the test is convenient, the cost is low, and the yield is high.

The utility model discloses a tool for improving liquid injection efficiency, which relates to the technical field of battery cell liquid injection and comprises a constant-temperature heating water tank, a water heating pipe, a vertical liquid injection pipe, a transverse liquid injection pipe I and a transverse liquid injection pipe II, a semicircular bent pipe is arranged between the first transverse liquid injection pipe and the second transverse liquid injection pipe, a switch control valve is arranged on the semicircular bent pipe, a hollow pipeline with the closed upper end is arranged on the top of the vertical liquid injection pipe, and a water heating pipe is arranged on the outer wall of the vertical liquid injection pipe in a winding mode. Two ends of the water heating pipe are respectively communicated with a water inlet and a water outlet of the constant-temperature heating water tank. The utility model aims to shorten the temperature difference between the processes so as to shorten the process time on one hand, and promote electrolyte infiltration on the other hand.

The invention relates to a preparation method and application of a novel TIL with a TOX gene knocked out, in particular to an engineered immune cell, and the TOX gene in the engineered immune cell is knocked out or knocked down. The ferroptosis resistance of the immune cell provided by the invention is remarkably enhanced, the immune cell can be better infiltrated into a tumor microenvironment, and the immune cell has a remarkable anti-tumor effect.

The invention belongs to the technical field of biology, and particularly relates to application of an Mgst2 gene serving as a target to preparation of a product for treating rheumatoid arthritis related interstitial lung diseases. According to the invention, it is found for the first time that Mgst2 can be used as a biomarker for treatment of rheumatoid arthritis related interstitial lung diseases, targeted knock-down is carried out on Mgst2 in neutrophils through an AAV9-shRNA vector (AAV9-shRNA-Mgst2) driven by a Cd11b promoter, and lung lesion progress can be effectively relieved by inhibiting NET formation. The Mgst2 inhibitor provided by the invention can directly intervene in the occurrence and development process of diseases from a molecular level, and has the advantages of accurate effect, remarkable curative effect, low side effect and the like. Compared with a traditional non-specific treatment mode, the product takes effect only aiming at specific molecular targets, damage to normal cells and tissues is remarkably reduced, and therefore the risk of toxic and side effects is reduced.

The invention relates to a preparation method of a high-temperature-resistant cellulose diaphragm for a lithium ion battery, the diaphragm and the battery. The preparation method comprises the following steps: carrying out ball-milling pretreatment on a bacterial cellulose dispersion liquid to obtain a pretreated dispersion liquid; filtering the pretreated dispersion liquid, and dropwise adding a pore-forming agent to the pretreated dispersion liquid to obtain a bacterial cellulose membrane; and carrying out hot pressing treatment on the bacterial cellulose membrane to obtain the bacterial cellulose diaphragm. According to the scheme provided by the invention, the high-temperature resistance of the diaphragm can be improved, relatively good dimensional stability and structural integrity can still be kept at relatively high temperature, meanwhile, the diaphragm has a rich and appropriate pore structure, and a large number of channels can be provided for migration of lithium ions, so that a battery keeps relatively high charge-discharge efficiency and relatively good safety performance.