The invention provides moisturizing cream and a preparation method thereof. The moisturizing cream comprises: by mass, 5-40%, preferably 10-25%, more preferably 15-35%, of a grease; 2.1-20%, preferably 2.5-10%, more preferably 3-8%, of an emulsifier; 1-40%, preferably 5-30%, more preferably 10-25%, of a humectant; 0-2%, preferably 0.1-2%, more preferably 0.1-1%, of a thickener; 1-10%, preferably 2-10%, more preferably 5-10%, of a skin conditioner. The emulsifier is a composite emulsifier composed of polyglyceryl-6 stearate, jojoba esters, polyglyceryl-3 beeswax, and cetyl alcohol. The moisturizing cream can form a constantly moisturizing protective film with better moisturizing degree on the skin surface, which is a bionic skin sebum film.